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Dr Sampson: Your Oral Microbiome Is Linked To This Disease!

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Dr Sampson: Your Oral Microbiome Is Linked To This Disease!

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2778 segments

0:00

Is there a link between our oral health

0:01

and our fertility?

0:02

Yes. This is some of the newest research

0:04

that's coming out and they found that

0:06

over 90% of men who wasn't able to

0:08

conceive with their partners had an oral

0:10

disease. With those who got treated,

0:11

there was a 70% improvement in

0:13

pregnancy. Now, research has also found

0:15

that if a woman has gum disease, it

0:16

takes them 2 months longer to conceive.

0:19

And I'm the only one who's talking about

0:20

it.

0:21

And who are you?

0:22

I am the saliva queen.

0:23

Dr. Dr. Victoria Samson is the

0:25

trailblazing dentist

0:26

whose datadriven research has uncovered

0:28

the shocking link between our mouths

0:30

and some of the world's most destructive

0:31

conditions. More than 90% of diseases

0:34

can be traced back to our microbiomes.

0:36

And we now understand that having an

0:37

imbalanced oral microbiome increases

0:39

your risk of high blood pressure, heart

0:41

disease, Alzheimer's, rheumatoid

0:43

arthritis, and even men who have gum

0:45

disease are 2.85 times more likely to

0:47

have erectile dysfunction.

0:48

Really?

0:49

Yeah. And then another study also showed

0:51

there's oral bacteria that can make

0:53

cancer more aggressive and harder to

0:55

treat as well.

0:55

But what is it that causes all of this?

0:57

Poor oral hygiene, sugar, stress, but

0:59

also some of us genetically will have

1:01

mutations which can cause disease. But

1:04

there's ways to fix it. For example, I

1:05

had a patient who had terrible arthritis

1:07

and terrible gum disease. And when I

1:09

treated the gum disease, her rheumatoid

1:10

arthritis got better to the point where

1:12

she was actually able to walk again.

1:14

Wow.

1:15

Yeah.

1:15

So, let's talk about what we can do

1:16

about it. Is there any time where I

1:18

shouldn't brush my teeth? Do I spit or

1:20

rinse after I've brushed my teeth?

1:21

Chewing gum, coffee, mouthwash, good or

1:24

bad for me?

1:25

Let's go through all of that. So,

1:27

weirdly,

1:29

this has always blown my mind a little

1:31

bit. 53% of you that listen to the show

1:33

regularly haven't yet subscribed to the

1:35

show. So, could I ask you for a favor

1:37

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1:38

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1:45

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1:48

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1:52

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1:55

continue to do what we do. Thank you so

1:57

much.

2:01

Dr. Victoria Samson, what is the mission

2:05

that you're on?

2:07

Um, my mission is to show people that

2:09

the mouth is the gateway to the rest of

2:11

the body. And if they really want to

2:13

achieve full body health, it starts with

2:14

the mouth first.

2:16

I've never heard of the term oral

2:18

microbiome

2:19

really until I met you and went through

2:22

all of your work and your research and I

2:25

think many people listening to this now

2:26

also probably aren't familiar with that

2:28

term or and also the importance of that

2:30

term. So if you had to make a case to

2:32

someone like me who's really unfamiliar

2:33

with this subject as to why it's so

2:35

important from a very topline

2:37

perspective,

2:38

what would you say? I think everyone

2:41

knows that their gut has a microbiome.

2:43

And for the past 10 years, we've always

2:44

talked about how you can change your

2:46

diet, probiotics, prebiotics for the gut

2:48

microbiome. But what a lot of people

2:50

don't understand is that the oral

2:52

microbiome is the second largest and

2:54

most diverse microbiome after the gut.

2:56

It's also a lot easier to change and

2:58

actually it's been shown to have a

3:00

massive impact on general health. So,

3:02

uh, having an imbalanced oral microbiome

3:04

increases your risk of oral diseases

3:07

like gum disease and decay, but also can

3:09

increase your risk of other systemic

3:11

diseases like high blood pressure, heart

3:13

disease, infertility, Alzheimer's. Um,

3:16

and it's something that is so easy to

3:18

manage and balance.

3:20

How many people does this impact and how

3:22

many people is it relevant to? So, an

3:24

understanding of my or oral microbiome

3:26

is going to help me in a number of ways

3:28

as it relates to my overall health. But

3:29

how many people does it really really

3:31

have an impact on?

3:33

I think it depends on what you're trying

3:34

to get out of the oral microbiome

3:36

testing. Um, I would argue that it

3:39

benefits everyone. We all have teeth. We

3:41

all have mouths. Um, and everything that

3:44

we do, every time we breathe, we eat, we

3:46

drink, we kiss, uh, we are impacting our

3:49

oral microbiome every single time. And

3:51

then every time we swallow or we breathe

3:53

that bacteria that is putting into our

3:56

mouth will travel elsewhere to the rest

3:57

of the body and cause problems

3:58

elsewhere.

3:59

You said it's the second biggest

4:01

microbiome in the body.

4:02

Yeah.

4:02

How many bacteria are in my oral

4:04

microbiome?

4:05

So you have 700 approximately 700

4:08

different bacteria which make up two

4:09

billion bacteria overall. And what's

4:11

also very weird about the oral

4:13

microbiome compared to any of the other

4:14

microbiomes is that you've got lots of

4:17

different environments or niches within

4:19

the same mouth. So, if you think about

4:20

the bacteria that would like to live

4:23

under the gums or at the back of your

4:25

throat or on your teeth, they're all

4:28

very different environments. Some are

4:29

hot, cold, you know, wet. And so, you've

4:32

got lots and lots of different parties

4:34

of bacteria within the same microbiome

4:36

in the mouth.

4:37

Okay. And you mentioned a second ago

4:40

that things like kissing, breathing,

4:42

swallowing have an impact on my oral

4:44

microbiome.

4:45

Yes.

4:45

In a significant way that I need to know

4:47

about.

4:48

Uh, yes. So, it's more about how often

4:50

you're doing those certain habits. So,

4:52

you know, for example, with kissing, the

4:54

research has shown that you need to kiss

4:56

more than 11 times a day for you to be

4:58

sharing the same bacteria or microbiome

5:00

as your partner. Um, but also even the

5:02

habits that we have, um, the air quality

5:04

that we have, everything will dictate

5:07

the environment that our mouths are

5:09

living in and therefore what bacteria

5:11

will live in our mouths. And on the

5:13

subject of oral diseases and things like

5:15

tooth decay, how many people are

5:17

impacted globally by oral diseases?

5:21

So the World Health Organization has

5:23

come out um saying that 3.5 billion

5:25

people have some sort of oral disease.

5:28

They've also found that 10% of our world

5:31

population are suffering from severe gum

5:33

disease which makes gum disease one of

5:36

the most prevalent inflammatory

5:37

conditions um in the whole body. this

5:40

conversation around the oral microbiome.

5:41

Have you seen it developing over the

5:43

over recent years, have you seen it

5:45

become more sort of pertinent to people

5:47

in society?

5:49

Massively. I think I've been doing this

5:50

for for years. It's been something that

5:53

I've loved. Um, and no one really knew

5:55

what I was talking about most of the

5:56

time. They all thought I was a bit of a

5:57

dreamer. Even dentists, patients, they

5:59

all thought, okay, well, doesn't really

6:01

matter, does it? But in the last year or

6:03

two, I've had people traveling from all

6:05

around the world just to get their oral

6:07

microbiome tested to understand more

6:09

about what's going on in their body. And

6:10

I think we're seeing a shift in the

6:12

generations in terms of this new

6:14

generation want to understand their

6:16

health a lot more. So we're all sitting

6:18

there wearing, you know, trackables,

6:20

wearables. We're, you know, calculating

6:22

how much sleep we have, how much we're

6:23

eating. And for uh now we're actually

6:26

also wanting to understand our oral

6:28

health. So that trust between a dentist

6:31

and the patient is not necessary

6:34

anymore. We want to actually understand

6:35

what's going on in their mouths and

6:37

actually, you know, be able to track

6:38

things, see what bacteria we have, how

6:40

much inflammation we have, our risk of

6:42

diseases, and what we can do to change

6:44

that.

6:45

Last question before I ask you a more

6:47

sort of personal question about

6:48

yourself. Um, what other diseases in my

6:50

body or sort of implications in my body

6:52

are linked and can be traced back to the

6:54

oral microbiome? We now understand that

6:57

more than 90% of diseases can be traced

7:00

back to an imbalanced microbiome. Uh if

7:02

we zone into just the oral microbiome,

7:05

it's got connections with infertility,

7:08

heart disease, diabetes, Alzheimer's,

7:10

rheumatoid arthritis. Um and the list

7:14

goes on. Erectile dysfunction. Um and

7:17

what's also very interesting going back

7:18

to your question about you know is there

7:20

been a new interest in this in the last

7:22

few years we've actually been able to

7:25

show that there is a strong connection

7:27

and causation between the oral

7:29

microbiome and general diseases whereas

7:31

prior to maybe 5 years ago there was a

7:34

lot of kind of is this correlation is it

7:36

just that okay there's the same risk

7:38

factors with gum disease and with heart

7:40

disease for example smoking and now

7:42

we're actually seeing that no it's not

7:44

just correlation there is strong

7:46

causation between the two.

7:47

And who are you?

7:49

Um, I am Victoria Samson. I'm a dentist.

7:53

Um, I do a lot on the oral microbiome.

7:56

Um, people call me the saliva queen.

7:58

That's my name on the streets.

8:00

And what's your sort of what

8:01

professional experiences and education

8:04

have brought you here today? And how

8:06

long have you been doing that? How many

8:07

mouths and how much saliva have you

8:08

seen? Give me a a sort of a a big view

8:11

on the the wealth of experience you have

8:12

on this subject. Um so originally I

8:16

trained as a dentist. Um and that's six

8:19

years of training. Um I would say I was

8:21

a pretty traditional conventional

8:24

dentist as I graduated. Um I'd done some

8:27

training um at the Karolinska Institute

8:29

during my university and the the

8:32

Karolinska Institute is the best dental

8:34

school in the world. Um but they're very

8:36

focused on the mouthbody connection on

8:39

testing saliva. Um, and what they

8:41

thought was that, you know, you go to

8:43

your doctor and you have a blood test.

8:44

Why don't you go to your dentist and get

8:45

a saliva test? So, from even dental

8:48

school, I had this in the back of my

8:49

mind, but I still didn't have the

8:52

training. And so, I just became a

8:53

dentist. Um, I was working half NHS,

8:56

half private, and then as time evolved,

8:59

I then, um, shifted to fully private.

9:02

Um, and then when COVID happened, um, I

9:05

started doing a lot of research and all

9:06

the dental practices were closed across

9:09

the country. Um, and I thought that was

9:11

crazy because basically the government

9:13

was saying dental practices, uh, or

9:15

dentistry is not a necessity. So, uh, I

9:18

thought that was insane. And so I

9:21

decided to do a lot of research and I

9:23

wrote a paper which was connecting, um,

9:26

oral health with poor with CO

9:28

complications. So what we found was that

9:30

patients who had poor oral health or gum

9:32

disease were at a much higher risk of

9:34

COVID complications. Um and then that

9:38

evolved into me doing some studies with

9:39

universities and hospitals. But the

9:42

issue was that we couldn't go into um

9:45

hospitals and check people's teeth and

9:47

gums because they had CO. So instead

9:49

what we did was we would collect their

9:50

saliva and we would take it to the lab

9:53

and we had this beautiful snapshot of

9:55

what was going on in a patient's mouth

9:57

at that moment in time just from their

9:59

saliva. So we did a lot of research and

10:01

we found that uh COVID sufferers or

10:04

patients who had gum disease were nine

10:06

times more likely to have COVID

10:07

complications. But also what I took from

10:10

that was that why aren't we using saliva

10:12

you know more regularly? Why don't we

10:14

use this in more commercial aspect and

10:16

for our patients. So after that I

10:19

devoted a lot of time into developing

10:21

oral microbiome testing. We had gut

10:24

microbiome testing. you've got urinary

10:26

microbial, you've got every single

10:27

microbiome has a test, but the oral

10:29

microbiome didn't really have one. So, I

10:32

built one of the first oral microbiome

10:33

tests in Europe um and that was a couple

10:35

of years ago and then now have come out

10:38

and uh kind of left and created my own

10:41

one um about a couple of weeks ago.

10:45

That research you mentioned,

10:46

specifically the research paper which

10:48

was titled, could there be a link

10:49

between oral hygiene and severity of co

10:52

infections

10:53

was the first research paper to link gum

10:55

disease with worse co complications and

10:59

I was reading that it was the most cited

11:02

research paper by the one of the sort of

11:05

dentistry publications.

11:06

Yeah. Yeah. So the British dental

11:08

journal is one of the most cited and

11:09

viewed articles. Um and what it also

11:12

helped do was um the World Health

11:14

Organization and SAGE picked that up and

11:17

they said, "Oh, wait a second. I think

11:19

that oral health is really important for

11:21

general health and also we should reopen

11:23

dental practices." So this also paved

11:25

the way for dental practices reopening

11:27

later on.

11:28

What's going on there? Can you explain

11:29

that to me like a 10-year-old? So if I

11:32

have a bad or a unhealthy oral

11:35

microbiome, I'm nine times more likely

11:38

to end up in ICU with CO complications.

11:41

What what's the link?

11:43

So there's a few. So the first one is

11:45

inflammation. So CO we know um it

11:49

releases a lot of inflammatory markers.

11:51

So it's what we call the cytoine storm.

11:53

So it's essentially the storm of lots

11:55

and lots of inflammatory markers. And

11:57

gum disease separately um is essentially

12:00

inflammation of the gums. And so what

12:02

gum disease does is it releases lots of

12:04

inflammatory markers from the mouth

12:06

elsewhere to the rest of the body. So

12:07

then when you add those together and you

12:09

have your cytoine storm from COVID and

12:11

you've got your inflammatory markers

12:13

from gum disease, it's just adding

12:15

petrol to the fire. So you're just

12:16

making that cytoine storm even worse.

12:19

Um but then on the separate side, it's

12:20

also bacteria. So if you look at the um

12:23

autopsies and the research of CO uh

12:26

patients um most of them didn't die from

12:28

the virus itself. You no one really died

12:30

from COVID 19. They died from

12:32

complications. So the number one

12:34

complication was actually a bacterial

12:36

infection. So imagine your body you've

12:38

got COVID you are really unwell and your

12:41

immune system is on absolute overdrive.

12:44

This is the prime time for bacteria to

12:46

come into your body and to cause what we

12:48

call a bacterial super infection. And so

12:50

actually when you looked at the

12:51

autopsies of a lot of these patients,

12:53

they had oral bacteria from their mouth

12:56

traveling to their lungs and causing

12:58

bacterial super infections which would

13:00

result in things like pneumonia. And

13:02

that's actually the cause of death for

13:03

most patients.

13:05

You don't really think that your oral

13:07

microbiome can be fatal. It can kill

13:10

you.

13:11

No. And even I think as a dentist we

13:15

weren't really taught how important

13:17

bacteria was or how important the mouth

13:20

was for the rest of the body. Uh the

13:22

number the only one that we ever learned

13:24

um and a lot of people would know this

13:26

one is that if you um have heart surgery

13:30

you can't actually have a hygiene for

13:32

about 6 months after the heart surgery.

13:34

A dental hygiene.

13:35

Yes. And the reason for that is because

13:37

you're at a very high risk risk of

13:39

something called infective endocarditis.

13:41

So this is oral bacteria which travels

13:43

down to a faulty heart valve um and can

13:46

actually cause death. Um so we know that

13:48

but we never really look at it for other

13:51

diseases or other problems.

13:53

I want to um I want to take a step back

13:55

before we go through the links between

13:57

our oral microbiome and all of these

13:59

diseases. But also I really want to also

14:00

talk about how what we can do about it

14:02

because I've got so many questions

14:03

around it. I've got all of these

14:05

products down below my chair from

14:06

mouthwashes to toothpaste to all these

14:08

kinds of things which I want to talk

14:09

about as well. But just taking a step

14:11

back to something that one of my guests

14:12

previously was telling me about. I think

14:14

it was James Nester. He was telling me

14:16

that the the mouth itself and the jaw

14:19

because of processed foods is an

14:22

abnormal shape. And when I say abnormal,

14:24

I mean um in relation to how it was

14:26

supposed to develop because we're eating

14:28

so many processed foods which aren't,

14:30

you know, which are designed to be easy

14:31

to chew. the mouth itself and the jaw

14:34

have changed. Is there any truth in

14:35

that?

14:36

Yeah, 100%. So, there was a man called

14:39

Western Price um and he was a dentist

14:42

and he basically suspected that and he

14:44

was like, "This is strange. Why is it

14:46

that um people who are in more

14:49

industrialized and westernized areas

14:52

have higher levels of decay and they

14:53

have loads of crowding?" So, they had

14:55

basically lots of crowding of the teeth

14:58

um and sper jaws. And so he basically

15:00

traveled around the world and he looked

15:02

at lots of different um tribes,

15:05

villages, countries and he compared the

15:08

teeth of uh for example twins. One twin

15:11

would be in a very industrialized

15:13

westernized area and the other one was

15:15

not. And what he found was that in the

15:18

twins who were in these

15:19

non-industrialized areas, they were

15:21

eating harder foods. Uh they were having

15:24

less sugar and actually their jaws

15:26

developed a lot better. So they didn't

15:27

have crowding. They had perfect teeth

15:29

actually and they had no decay compared

15:32

to the children or the the twins who are

15:34

in more industrialized areas and it is

15:37

because our food now has become so

15:39

processed. A lot of children are not

15:41

having hard foods. Um and so we don't

15:44

develop the jaws and the muscles at an

15:46

early age and so the teeth haven't

15:48

changed size. The teeth are exactly the

15:49

same size as they were previously. But

15:51

what we're seeing is that those teeth um

15:54

don't have any space to grow anymore and

15:55

that's when we're getting crowding. And

15:57

can you see that in any of those models?

15:59

So, uh, yeah, in this model you can

16:02

actually see at the very back. So, a lot

16:03

of people will have wisdom teeth. Um,

16:05

and, uh, one of the biggest issues at

16:08

the moment is that a lot of people have

16:09

impacted wisdom teeth. So, this is

16:11

basically, imagine your teeth are all

16:13

upright. Your wisdom tooth is coming out

16:15

at a completely horizontal angle and

16:17

it's pushing on the rest of the teeth.

16:19

It's an absolute nightmare as a dentist

16:21

to take out. It's even more of a

16:22

nightmare for a patient to have to

16:24

endure. But also we're seeing that there

16:26

are a lot more impacted wisdom teeth um

16:29

in the last 30 40 years than there were

16:31

previously

16:32

uh because the diets have changed.

16:33

Because the diets have changed a lot

16:34

more children are needing orthodontic

16:36

treatment now as well just because they

16:38

have crowded teeth. Teeth are

16:40

overlapping um and so they need braces

16:42

to straighten those teeth out. If you

16:44

think about cavemen, cavemen didn't have

16:47

dentists. They didn't have braces. They

16:49

didn't even use toothpaste. But they

16:51

didn't die from gum disease or decay or

16:54

crowded teeth. So, it's been something

16:56

in our industrialized or more kind of

16:59

westernized diet that has changed that.

17:02

My wisdom tooth is coming through on my

17:04

left side at the moment and I think

17:05

actually also my right side at the same

17:06

time. And I'm 32 years old now. So, I'm

17:09

like, why why the hell am I growing

17:10

teeth at 32 years old? I thought I was

17:12

on my way out or something. Um, so I got

17:14

two questions just before we crack on,

17:16

which is what the hell is a wisdom

17:17

tooth? Why is it called a wisdom tooth

17:18

and why is it coming through at 32 years

17:20

old?

17:21

Um, so we have teeth erupting at

17:24

different kind of times of our lives. So

17:28

usually you have your baby teeth, they

17:30

will erupt up to the age of about 6 or 7

17:32

years old. Um, and then you have your

17:34

adult teeth coming through and usually

17:36

they will stop erupting around 12 years

17:38

old. Um, and then you have nothing.

17:40

You're chilling. You have nothing,

17:41

nothing, nothing nothing until about

17:43

maybe 18, 19 years old. And that's where

17:46

you start to get your wisdom teeth. The

17:49

name behind wisdom teeth from what I

17:51

understand is because it's it erupts

17:54

when you're older. It's when you have

17:55

more wisdom and you're more wise. So I'm

17:57

wise now.

17:57

So you're just very wise.

17:59

Okay, makes sense.

18:00

And so some people will get it at 18.

18:03

Some people don't have any wisdom teeth.

18:05

Some people will have wisdom teeth which

18:06

erupt perfectly and are all completely

18:08

fine. and others will have their wisdom

18:10

teeth tooth erupt at 32 years old and

18:12

maybe be a little bit impacted or cause

18:14

problems. So, they're also very strange

18:18

teeth. Um, they're very unpredictable

18:20

the way that they are.

18:21

Is there any evolutionary basis for why

18:23

we need them? There must be some kind of

18:25

evolutionary reason for them.

18:27

Not that I understand. What is also

18:30

happening is that um apparently and this

18:32

is some research is that less people are

18:34

having wisdom teeth because more

18:37

children or or adults are getting their

18:39

wisdom teeth taken out and as evolution

18:42

goes um eventually some people are

18:45

actually not having wisdom teeth at all

18:46

because their ancestors haven't had

18:48

wisdom teeth so why would they have

18:49

wisdom teeth? Um but overall no there's

18:52

no real need for wisdom teeth. I never

18:56

like to take them out unless needed

18:58

because I mean more teeth

19:00

the better

19:00

the better and you never know if you

19:02

have to have something taken out and we

19:04

can use your wisdom teeth for something.

19:06

If I were to look at my ancestors from

19:09

500 years ago, you said they don't have

19:11

dentists, they don't have toothpaste and

19:12

all those kinds of things. But you also

19:14

said they don't have tooth tooth decay.

19:16

Yeah.

19:16

Does that not therefore mean that I

19:19

shouldn't need a dentist and I shouldn't

19:20

need toothpaste or mouthwash or floss?

19:23

If you had a caveman diet, then

19:26

potentially you might not need

19:28

toothpaste, floss, or even a toothbrush.

19:31

Um, and there's a lot of argument as to,

19:33

you know, there's a lot of people out

19:34

there saying, you know, you don't need

19:36

to use any toothpaste, you don't need

19:37

floss, anything like that. And fine, go

19:40

ahead, do that. But only if you are

19:42

going to be eating, you know, meat, raw

19:45

meat sometimes, and you're only drinking

19:47

water and you're not having anything in

19:50

your diet which has any sugar or

19:52

carbohydrates in it.

19:53

I mean, doesn't that speak to what the

19:54

perfect diet is supposed to be? Can't we

19:56

tell what the perfect diet is supposed

19:58

to be by looking at the mouth?

19:59

Yeah. So, uh, another issue is that with

20:02

a lot of the food that we eat now, um,

20:05

they have a lot more sugar in them and

20:07

that will impact the acidity of your

20:08

saliva. And essentially what decay is

20:11

is, uh, you have sugar or you have some

20:14

sort of carbohydrates and you've got

20:16

this bacteria in your mouth and they

20:18

feed on that sugar. And as they feed on

20:20

that sugar, they release acid. Um, and

20:23

if that acid is left there, then it can

20:25

cause demineralization of your teeth.

20:27

and that demineralization will end up

20:29

with decay.

20:31

Okay. So, let's talk about the personal

20:35

oral microbiome. Um, is my oral

20:37

microbiome different from say Jack's

20:39

over there and from my girlfriends?

20:42

Yes. Massively.

20:43

Massively different.

20:44

Yes. Maybe massively I would say. Um, so

20:48

one of the issues that I used to have

20:50

was I was doing lots of oral microbiome

20:52

testing. Um, and I would have, you know,

20:55

let's say you and your girlfriend do an

20:57

oral microbiome test and both of you, I

20:59

would see your results and they would

21:00

come out pretty much the same because

21:02

we're only looking at certain bacteria.

21:04

We can't look at all 700. So, we would

21:06

look at the top 20 bacteria that cause

21:08

problems. So, I would look at both of

21:10

them and then I would look inside your

21:11

mouth and one of you, I don't know in

21:14

this case, had raging gum disease and

21:16

terrible, terrible oral health and the

21:19

other person would be completely fine.

21:20

So then I realized that actually it's

21:22

not just bacteria that causes disease or

21:25

problems, it's how your body responds to

21:27

that bacteria and the strains of

21:29

bacteria that you have as well. So for

21:31

every bacteria um there'll be multiple

21:34

strains and some of those strains can be

21:36

really aggressive and really horrible

21:37

for your mouth and other strains are

21:39

completely fine and are not going to

21:41

cause you any problems. So when I

21:43

developed my test, what we did is we

21:45

looked at strains. So we looked at the

21:46

strains of certain bacteria um and we

21:49

would be able to differentiate between

21:50

patients who had the really bad strains

21:52

and the really good strains. But then

21:54

also we looked at the ratio of good and

21:56

bad bacteria in someone's mouth. So

21:58

their diversity as well as their genetic

22:00

mutations and also their inflammation.

22:02

So when you put all of it together and

22:04

you it's like a puzzle piece then you

22:06

can actually have a better insight into

22:08

someone's oral health. So, I guess my

22:11

answer is that everyone's oral

22:13

microbiome is a little bit different,

22:14

but it's also how your body responds to

22:16

that microbiome and bacteria that really

22:18

dictates whether or not you're going to

22:20

have disease or problems.

22:21

So, you could be someone who takes care

22:23

of their teeth really, really well, but

22:24

still have a bad oral microbiome

22:27

relationship with the rest of your body

22:29

effectively.

22:30

Yeah. And I see it every day. And we

22:31

have a lot of patients who suffer from

22:33

terrible gum disease and they come to me

22:35

and they brush three times a day.

22:36

They've never touched a cigarette. They

22:38

have immaculate oral hygiene. They eat

22:41

very well, but they have terrible gum

22:43

disease. And for those patients, they

22:44

might have genetic mutations that

22:46

predispose them to gum disease and to

22:49

inflammation. So even the smallest

22:51

amount of bacteria, their body responds

22:53

in a very aggressive and inflammatory

22:56

destructive way, which can cause

22:57

disease.

22:58

When I was speaking to I think it was

22:59

Tim Spectre about the gut microbiome, he

23:01

was telling me that the gut microbiome

23:03

turns over, i.e. the bacteria dies every

23:06

couple of days or weeks or something.

23:09

How often does the oral microbiome die

23:14

turn over and why does that matter?

23:16

So, what's interesting or different

23:19

between the oral and gut microbiome? The

23:20

oral microbiome, if someone doesn't go

23:23

in there and mechanically disrupt the

23:25

bacteria and the plaque in your mouth,

23:28

then that bacteria can stay forever. So,

23:30

the gut, what happens is you've got

23:31

something called paristelis. got

23:33

movement. So the bacteria moves, it it

23:35

changes, it regenerates, there's

23:37

turnover in the mouth. So the teeth are

23:39

the only non-shedding surfaces in the

23:41

whole body. So that

23:42

non-shedding surfaces.

23:44

So imagine if you if you never had a

23:46

shower in your life. Uh you would still

23:49

selfwash because the skin cells would

23:51

shed.

23:52

Mhm.

23:53

But if you never brushed your teeth,

23:55

then your teeth are not shedding.

23:56

They're going to stay like that. So that

23:58

bacteria will just keep on growing and

24:00

growing and growing and growing and

24:02

you'll get this really thick plaque. So

24:05

that's why actually the oral microbiome

24:07

you need to mechanically remove that

24:09

bacteria and that's why brushing your

24:10

teeth is super important or um using the

24:13

correct toothpaste or etc. going and

24:15

seeing your hygienist because you need

24:17

to mechanically remove that bacteria

24:19

quite regularly.

24:21

Okay. And the the two ways I was reading

24:23

in your work it said that the two ways

24:24

that oral health impacts overall health

24:26

are by the spreading of bacteria and the

24:28

other sort of central issue is it causes

24:30

inflammation.

24:31

So on this point of spreading bacteria

24:34

I'm always concerned this is a bit of a

24:36

superstitious thing but anytime that I'm

24:38

sick I'm always like don't part of me is

24:40

like don't swallow because in my head I

24:42

think if I'm sick in my mouth or if I've

24:44

got um like a sore throat or something

24:46

I'm like if I swallow it the rest of my

24:48

body is going to get sick. It's super

24:50

super superstitious, but is there any

24:52

truth to any of this?

24:54

Um, so not from just being sick like a

24:56

common cold. And it's actually really

24:58

interesting. I had a patient yesterday

24:59

and bless him, he's very young, 7 years

25:01

old. Um, and he had exactly that same

25:05

mindset. He just randomly woke up one

25:07

day and he said, "This is kind of gross.

25:09

Why am I swallowing my saliva? There's

25:11

all these bad bugs and gross things in

25:13

my saliva and I'm swallowing it every

25:14

day and it's traveling to the rest of my

25:16

body at seven." And so what he ended up

25:20

doing was refusing to swallow his own

25:22

saliva. And so he would basically just

25:24

dribble and he would just wipe his the

25:27

saliva off with a sleeve or he'd carry a

25:29

towel with him and just wipe it. So

25:31

bless him, he had a big rash around his

25:32

his um his face. Um and it it was a bit

25:37

of a weird moment for me because I was

25:39

like, you're kind of right. Like I mean

25:41

it is a bit weird especially as a child

25:43

to sit there and think like yeah you've

25:45

got 700 different bacteria two billion

25:47

bacteria overall and then you're

25:49

swallowing it and it can travel

25:50

elsewhere to the rest of the body. So

25:52

yes in in short yes bacteria from your

25:55

mouth when you swallow it can travel

25:57

elsewhere to the rest of the body.

25:59

However a lot of the bacteria um dies.

26:02

So the acid in the stomach can kill a

26:05

lot of the bacteria. So it's only the

26:06

really really bad bacteria that are able

26:09

to survive and cause problems. And

26:10

that's why it's so important that you

26:12

have a good oral microbiome and you

26:13

balance it well.

26:14

And the other central way that it can

26:16

cause

26:18

negative impacts to your overall health

26:19

is via inflammation. What is the link

26:22

between inflammation and my my oral

26:24

microbiome? So it's uh something that we

26:28

call lowgrade chronic inflammation and

26:30

imagine so you've got this delicate

26:32

balance of bacteria in your mouth which

26:34

is your microbiome and we all have bad

26:36

bacteria in our mouths but most of us

26:39

hopefully have better levels or higher

26:42

levels of the good bacteria. So there's

26:44

always that balance and what happens in

26:46

an imbalanced oral microbiome is that

26:48

shift changes. So you get higher levels

26:50

of bad bacteria and you don't have

26:52

enough good bacteria. These bad bacteria

26:55

firstly yes they can travel elsewhere to

26:56

the rest of your body as you discussed.

26:58

The second is that they can release

27:00

inflammatory markers. So they basically

27:02

release inflammation and this

27:04

inflammation can travel from your mouth

27:06

to the rest of your body and contribute

27:08

to inflammation elsewhere. So for

27:10

example if you had rheumatoid arthritis

27:12

and then you had inflammation from your

27:14

gums that inflammation from your gums is

27:17

making your arthritis in your wrists

27:19

worse. So it's contributing to it. Now

27:22

what's also interesting and that's why

27:24

it's called lowgrade chronic

27:25

inflammation is often you wouldn't even

27:27

know that you have it. I have so many

27:29

patients who say oh you know my gums

27:31

bleed but that's normal. If your eye

27:33

bled or if your foot was bleeding every

27:36

day you would be worried and you would

27:38

think actually there's inflammation

27:40

here. There's a problem here. But so

27:42

many people have bleeding gums and they

27:43

don't understand that bleeding gums is a

27:46

sign. It's your gums screaming to you

27:47

saying that I have inflammation and that

27:49

inflammation can travel. And then the

27:52

third mechanism as well. So there's one

27:54

more is um it's damage to your blood

27:56

vessels. So again the same bad bacteria

27:58

in your mouth. It releases these

28:00

enzymes, these toxic enzymes and they

28:03

can travel through the rest of your body

28:04

through your blood vessels and they can

28:06

actually damage your blood vessels. So

28:08

these blood vessels are not able to

28:10

dilate and constrict as well as they

28:12

used to.

28:13

On that point of arthritis, I read a

28:15

stat which um I believe is true. I think

28:17

it actually came from some of your

28:18

research that said people with

28:19

rheumatoid arthritis are eight times

28:21

more likely to develop gum disease than

28:23

patients without rheumatoid arthritis.

28:26

Yes.

28:27

Which is shocking.

28:28

Yeah. So there's a really strong um

28:30

birectional relationship between

28:32

rheumatoid arthritis and gum disease. So

28:34

that means that if you have really bad

28:36

rheumatoid arthritis, you will have

28:38

pretty bad gum disease. And if you treat

28:40

your rheumatoid arthritis, your gum

28:42

disease will get better. and vice versa.

28:44

If you have if you treat the gum

28:46

disease, your rheumatoid arthritis will

28:47

get better. And that was actually one of

28:49

the um first patients that really got me

28:53

on my journey of the mouthbody

28:55

connection. So like yeah, I was doing

28:56

the saliva testing. I got it. You know,

28:58

I was like, "Okay, cool. We are

29:00

quantifying oral health. We're tracking

29:02

things." But even me, I wasn't really

29:06

fully sold on this whole mouthbody

29:08

connection, how our mouth is connected

29:09

to the rest of the body. So, I had a

29:11

patient who was sent to me by um her

29:13

functional medicine practitioner and she

29:16

had been seen by uh four or five

29:18

different practitioners. She had

29:20

terrible rheumatoid arthritis and she um

29:23

went to this final guy and he was the

29:25

first guy to ever ask her, "Have you

29:27

ever had your teeth checked? What's

29:28

happened?" And she said, "Oh, I've had a

29:30

few teeth taken out in the last year or

29:32

two, about six teeth, but you know, it's

29:34

just it is what it is." And he was like,

29:36

"I I don't think that's normal." So he

29:39

sent her to me and he was like, "Can you

29:40

do your saliva stuff that you do and see

29:42

if there's anything up going on there?"

29:44

And we did do a saliva test, we saw that

29:46

she had super high levels of

29:48

inflammation, of collagen breakdown, um

29:51

high levels of bad bacteria. And what

29:54

was the most important was that when I

29:56

treated her gum disease, she had

29:57

terrible gum disease and that's why she

29:59

was losing her teeth. When I treated the

30:01

gum disease properly and aggressively,

30:03

um, yes, her gums healed, but more

30:05

importantly, her rheumatoid arthritis

30:07

got better to the point where she was

30:09

actually able to get off steroids and

30:11

medication and be able to walk again.

30:14

Wow.

30:14

Yeah.

30:16

By treating her gum disease.

30:17

Yeah. And I think that, you know,

30:19

sometimes as a dentist, we treat a lot

30:22

of gum disease and we treat a lot of

30:23

things and we don't necessarily see the

30:26

systemic consequences because the

30:28

patient doesn't come back or you know um

30:31

or it's such a small impact that you

30:33

don't necessarily see it. But this was

30:35

the one time where I was like wow like

30:37

what we do is actually really really

30:40

insightful and really important. And you

30:42

mentioned alongside that um inflammation

30:44

also has an impact on cardiovascular

30:46

functioning and health. I believe it's

30:49

the case that cardiovascular disease is

30:51

the biggest killer in the world from

30:52

what I understand. Um so I was wondering

30:55

if if you knew any of the stats that

30:57

show the impact or the the increased

31:00

likelihood of me having a heart attack

31:01

or a stroke or something based on my

31:03

oral microbiome.

31:06

So um the research has shown that if you

31:08

have gum disease you are at a 20% higher

31:11

chance of high blood pressure. Um but

31:13

also they are now saying that up to 30

31:16

to 40% of cardiac um issues in hospital

31:21

can be traced back to an oral bacteria

31:25

um causing problems in the heart valve.

31:27

Um so the reason for this connection so

31:30

yes inflammation but also going back to

31:33

that third mechanism I told you which

31:35

was about the vasoc constriction so the

31:37

blood vessels constricting and dilating.

31:40

So these toxic enzymes which are being

31:41

released by the bacteria they travel

31:43

through the blood um and they basically

31:46

stop the blood vessels from being able

31:48

to widen and lots of blood to travel to

31:51

the heart and also to constrict and that

31:53

also is um one of the biggest

31:55

connections with uh heart disease.

31:57

I found this stat which might well be

31:59

from your work or someone else's. It's

32:00

from the study called the association

32:01

between parodontitis and blood pressure

32:04

highlighted in systemic systemically

32:06

healthy individuals.

32:08

Not mine but okay. And it found that

32:10

people with gum disease were twice as

32:12

likely to have a heart attack and three

32:14

times as likely to have a stroke than

32:16

those without inflammatory gum disease,

32:18

which is absolutely staggering.

32:21

Yeah. And then another study also showed

32:23

that when you treated someone's gum

32:25

disease, their levels of CRP, and CRP is

32:28

an inflammatory marker that you can

32:30

check in your blood, the levels of CRP

32:32

significantly reduced. And for a lot of

32:34

patients who suffer from heart

32:36

conditions, they will get their CRP

32:37

quite regularly checked through blood

32:39

testing.

32:40

And so this is a way of reducing their

32:42

inflammation is just by having a a

32:43

simple hygiene. And I've even seen um

32:46

particularly in America, there's a lot

32:48

of um uh cardiac surgeons and um doctors

32:52

related to to heart health um who are

32:55

now actually working with dentists

32:58

because they understand that if they

32:59

work together, then they're going to

33:01

have far better results for their

33:02

patients. And this is this is that

33:05

swallowing thing we're talking about.

33:06

This is because you're swallowing that

33:07

bad bacteria.

33:08

Yeah. And your heart valve um imagine if

33:10

it's been it's faulty. Imagine you just

33:12

had surgery. I always think of it like

33:15

it's sticky. It's like velcro. So it's

33:17

really prone to infection and problems.

33:19

It's just like if you fell over and you

33:21

had a scab and you were rolling around

33:23

in mud all the time, you would get

33:25

bacteria going into that scab and

33:26

causing problems. There's the same thing

33:28

with your heart valves.

33:29

Doesn't the bacteria just travel on its

33:30

own anyway? Cuz I feel like it's in my

33:32

mouth. So I feel like it I don't know

33:34

these are living organisms don't they

33:35

just like find their way down even if I

33:37

don't swallow.

33:38

Yeah even through your blood um and also

33:41

through your gums as well. So you can

33:43

swallow your bacteria breathe it or it

33:46

can go through your blood.

33:47

At the start of this conversation we're

33:48

talking you mentioned the sort of

33:50

implications for your cardiovascular

33:51

system and one of the things you said

33:52

was erectile dysfunction and that was

33:55

slightly alarming to me as a man

33:57

um who's trying to stay away from

33:59

erectile dysfunction. What is what is

34:00

the research that supports this idea

34:03

that my oral microbiome can have an

34:04

impact on my erectile functioning?

34:08

So men who have periodontal disease are

34:10

2.85 times more likely to suffer from

34:12

erectile dysfunction.

34:14

2.8 times.

34:15

Yeah.

34:16

Is I'm pretty sure that's 280% isn't it?

34:18

Yeah.

34:19

Okay. So what is this perodontal

34:20

disease?

34:21

Gum disease. Okay. So uh it's kind of I

34:24

would say it's a bit of a spectrum. So

34:26

the early stages of perodontal disease

34:29

or gum disease is just gum inflammation.

34:31

So that's that patient who is brushing

34:33

their teeth, spits in the basin and sees

34:35

blood. So that's the you know the early

34:37

inflammation. If they don't get that

34:39

checked out and sorted that will just

34:40

continue and continue and continue to

34:43

what we call gum disease. Um and that's

34:45

where yes you've got inflammation but

34:47

actually you have really high levels of

34:49

bad bacteria now. And this bacteria is

34:51

essentially eating away the gums and

34:53

also your bone. And uh it's it's now

34:57

become irreversible.

34:58

I'm just going to have a swig of this

35:01

for your thought this

35:06

and then at the very end of the spectrum

35:08

is people who are losing their teeth

35:10

having really terrible gum infections

35:12

and all of these kind of mouthbody

35:14

connections that we're talking about.

35:16

Okay. And that can you just explain

35:19

again as if I'm 10 the how my how that

35:23

gum disease that parodontitis is it

35:24

called

35:25

has an impact on my penis I don't

35:27

understand like I don't understand the

35:28

link it makes all of my blood vessels

35:30

exactly

35:31

yes so it essentially stops your blood

35:33

vessels from dilating

35:35

and so you've got reduced blood flow to

35:37

your penis

35:38

okay

35:38

and therefore

35:41

doesn't work

35:41

okay so this is an emergency this stuff

35:43

this is really is important

35:44

that's the one statistic whenever I have

35:46

a and in the chair and he's like, "Oh, I

35:48

don't want to brush my teeth." I'm like

35:49

2.85 times more likely to have erectile

35:51

dysfunction. They usually will go

35:52

straight to the bathroom to brush their

35:54

teeth.

35:54

The other thing, no, but it's true, but

35:56

also the other thing that I I read in

35:57

your research, which I found really

35:58

really um shocking is the link between

36:03

my oral health, my oral microbiome, and

36:06

cancer.

36:07

Yeah.

36:08

I was reading specifically about female

36:10

breast cancer,

36:11

um which I know is affects a lot of

36:13

women. um what is the link there between

36:15

breast cancer cancer generally and our

36:17

oral microbiome.

36:19

So this is um I would say some of the

36:21

newest emerging research that's coming

36:23

out. So with breast cancer um I didn't

36:26

know this before this research came out

36:28

but your breast has uh its own

36:30

microbiome. So that tissue within the

36:32

breast um different bacteria are able to

36:35

grow. And what they found was that in

36:37

women who had breast cancer, they had

36:40

high levels of certain oral bacteria in

36:42

their breast microbiome. So the oral

36:44

bacteria is called fusobacterium

36:46

nucleatum. And they compared the breast

36:49

microbiomes of patients who didn't have

36:52

breast cancer versus those who had

36:53

breast cancer.

36:54

Sorry, what's an oral what's a breast

36:56

microbiome?

36:57

Just the collection of bacteria in your

36:58

breast.

36:59

Okay.

36:59

Yeah. Um I didn't even know there was a

37:01

microbiome in your breast either, but

37:03

apparently so. And um so when they

37:05

compared a healthy um woman uh her

37:09

breasts to a woman who had breast

37:11

cancer, the woman who had breast cancer

37:13

had very high levels of the specific

37:15

oral bacteria called fusobacterium

37:17

nucleotum in their breast. Um there's

37:20

also been research on colurectal cancer.

37:23

Um and actually Apple News came out with

37:26

something couple of months ago which was

37:28

nice to see them kind of just spreading

37:30

the word. But what they found was that

37:32

in patients who had colarctal cancer um

37:36

more than 50% of them had the the exact

37:39

same oral bacteria from the breast

37:40

cancer study that fusobacterium

37:42

nucleotum in the colons and what they

37:45

found was that oral bacteria uh made the

37:49

cancer more aggressive and harder to

37:51

treat as well.

37:53

I was reading about a study in mice um

37:55

that linked that oral bacteria to tumor

37:58

growth. Mhm.

37:59

Are you familiar with that study?

38:01

Yes. And it's that specific oral

38:02

bacteria. So the fusacter nucleotum

38:05

which has been shown to accelerate tumor

38:07

growth um within mice but also um for

38:10

colorectal cancer and breast cancer as

38:12

well.

38:14

And what's your belief there? I know

38:15

this research is fairly new but do you

38:17

think there is a a causal relationship a

38:19

significant causal relationship between

38:20

the health of our oral microbiome and

38:22

our probability of developing some form

38:24

of cancer?

38:25

I wouldn't yet say causal. I think that

38:30

for most cancers it is multiffactorial

38:34

and there are a lot of things that can

38:37

impact whether or not you get the cancer

38:39

and how aggressive the cancer is. Um I

38:42

do think that oral health and some

38:44

specific oral bacteria um are risk

38:47

factors and can definitely increase the

38:50

um aggression of those cancers or even

38:53

the initiation of them. Um there's also

38:55

been research and I think I'm waiting

38:57

for the research to be published on what

39:00

they're doing is they've created a

39:01

antibiotic which only kills that oral

39:04

bacteria that I was talking about. So

39:06

fusobacterium nucleiatum and they are

39:08

going to be issuing that uh antibiotic

39:11

to those patients who have the colctal

39:13

cancer which has the oral bacteria to

39:16

see whether or not it slows down their

39:18

progression or improves their their

39:20

prognosis. So if I see those results and

39:22

it shows it, then there's for sure a

39:25

strong positive link between the two.

39:27

But for now, I would say that it's

39:29

multiffactorial and it's definitely a

39:30

risk factor.

39:31

That oral bacteria that you're

39:33

describing that you called it fuzo

39:35

bacterium.

39:35

Yeah.

39:36

What is it that causes that? Is it

39:38

something that I'm eating? Is it a

39:39

lifestyle choice I'm making?

39:41

Uh multiple things. Poor oral hygiene.

39:44

Um some of us genetically will have

39:46

higher levels of it. Um it's what we

39:48

eat. It's who we're kissing. It's what

39:50

we're breathing in.

39:51

Does my girlfriend have it?

39:54

So, we would have to see. Um, but it's

39:56

uh and that's the thing. That's the

39:57

beauty of being able to test these

39:59

things now is that you can actually see

40:00

and also what's it's strange is that

40:03

green tea um you know something so

40:05

simple is extremely effective at killing

40:08

fusoacterium nucleotum. So, it's just

40:10

knowing those types of things, being

40:11

able to do the test, knowing the right

40:13

treatment plans and recommendations

40:15

based from that. We know green tea is

40:17

good for us and now we can really

40:19

understand why.

40:20

Okay, that's interesting. You you have

40:22

actually tested Jack over there, right?

40:23

And you said to me before we started

40:24

recording that he's got a ton of that

40:26

fuzo bacterium.

40:28

Uh yes, he does. Yeah.

40:29

And it's really getting out of control.

40:31

That's what you said.

40:31

Really badly out of control. Yeah. So,

40:33

I've um

40:36

I've given him a big vat of green tea as

40:38

a gift.

40:39

Green tea?

40:40

Yes,

40:41

green tea.

40:43

This guy's going to edit that out. This

40:44

is the problem.

40:48

me up.

40:51

Green tea.

40:51

Yeah,

40:52

that's good for my own microbiome.

40:53

Yeah, really good. Stains, but really

40:55

good. Um, it's anti-inflammatory. Um, it

40:59

helps with what we call oxidative

41:00

stress. So, this is um, basically stress

41:03

of for the body. Um, and it's

41:05

antibacterial. So, it actually is very

41:07

effective at killing fusobacterium

41:09

nuclei.

41:10

What is your opinion of the impact that

41:12

coffee has on my oral microbiome? I'm

41:15

slightly biased because I love coffee.

41:17

Okay.

41:18

But there is no negative impact of

41:21

coffee on the oral microbiome directly.

41:25

Um coffee does dry your mouth out. Um

41:28

and so you have reduced saliva and that

41:30

can actually cause problems for the oral

41:33

microbiome. So the saliva is super

41:36

important in your mouth. It provides all

41:38

of the food, the proteins, everything

41:41

for the bacteria in your mouth. So, it's

41:42

kind of like this delivery service. Your

41:45

delivery roots traveling around

41:46

providing all the food and bacteria um

41:49

sorry, food to the bacteria and that's

41:51

what keeps the good bacteria alive and

41:53

happy. So, when you have a dry mouth,

41:55

let's say you're drinking lots of coffee

41:57

or you're very nervous or you are on

41:59

anti-depressants for example, um which

42:01

are a big one, then you just don't have

42:03

as much saliva. So you those bacteria

42:06

don't have as much food and those

42:08

bacteria die and then you get bad

42:10

bacteria growing in replacement.

42:12

What about tea? We're a nation of tea

42:14

drinkers in the UK.

42:16

Um similar. So it also does dry your

42:18

mouth. Not as bad as coffee, but

42:19

otherwise no problems other than

42:21

staining.

42:22

What about if I put loads of sugar in

42:23

it? Cuz a lot of people put a lot of

42:24

sugar.

42:25

Okay. Yeah. No, no, no. Never. No. No.

42:26

So actually sugar in your tea is even

42:29

worse than you having a biscuit for

42:32

example. Um so because the sugar

42:34

dissolves in your hot tea and the tea is

42:37

hot when you drink it um it can actually

42:39

cause more problems. Uh another thing

42:42

with sugar is um I have a sweet tooth. I

42:45

love sugar. But it's about how you eat

42:46

your sugar. So let's say if you have

42:48

your hot tea with five lumps of sugar in

42:51

there and you're sipping it over an hour

42:53

or two, that's where you start to see a

42:55

lot of problems. So actually you need to

42:57

be having a sugar attack. So just all

43:00

the sugar in one go. And that way your

43:02

mouth has all the sugar in one go and

43:04

it's able to neutralize the saliva and

43:06

get back to a good state as quickly as

43:08

possible. Every time you sip your your

43:11

tea with sugar, what happens is that the

43:13

saliva has to go from acidic back to

43:16

neutral, acidic, back to neutral,

43:17

acidic, and then it starts to just not

43:19

work properly and the saliva just stays

43:21

acidic and that's where you start to see

43:23

decay.

43:23

So you want to just down the tea,

43:25

down the tea or I don't know if you're a

43:27

M&M guy, have all your M&M's in one go.

43:30

Don't snack on M&M's every 10 minutes.

43:32

What about other drinks like, I don't

43:33

know, you know, Coca-Cas and these other

43:35

sort of fizzy drinks that might have

43:38

artificial sweeteners in things like

43:39

that.

43:40

So, they're not as bad as your natural

43:43

sugars. Um, but for example, something

43:46

like your Coke or or Fanta or whatever,

43:48

it's also um very acidic. Um, and it can

43:52

actually cause erosion as well. So this

43:54

is essentially where the outer layer of

43:56

your tooth, so the enamel is just worn

43:58

away from having lots and lots of these

44:00

fizzy drinks.

44:01

Okay. So that it's not going to cause

44:02

decay in the same way, but it might

44:04

change the acidic balance which then

44:06

decays my tooth, which makes me more

44:08

susceptible to when I eat sugar to

44:10

having a problem. Okay, got

44:12

so going back to what we were talking

44:13

about the the implications of an oral

44:15

microbiome and the rest of my body,

44:16

brain health is one thing that I was

44:17

really curious about. Um, we've had lots

44:19

of conversations on this show about

44:21

Alzheimer's and dementia and just

44:23

general sort of optimal cognitive

44:25

performance as I age. Something I'm

44:26

thinking a lot about. I want to have a

44:28

sharp brain. It's quite important

44:29

because of what I do. Um, so is there a

44:31

link between my oral microbiome and my

44:33

cognitive and brain health?

44:35

Yes. Um so if we look at actually just

44:39

the the occurrence of Alzheimer's um and

44:42

gum disease or oral health, a lot of

44:45

research has shown that um if you have

44:49

gum disease for more than 10 years, you

44:52

have a 70% increased chance of

44:54

developing Alzheimer's. So that was a

44:56

study that was done on over 20,000

44:58

people and they followed them for 20

45:01

years and they saw okay if you had gum

45:03

disease um at baseline whether or not

45:06

you get Alzheimer's at 10 years or 20

45:08

years so a 70% increased chance of it um

45:11

they've also done a lot of research

45:13

where uh they've been looking at oral

45:16

bacteria and what they found was that

45:18

there are certain oral bacteria so uh

45:21

one called p gingeralis that's one of

45:23

the worst oral bacteria I would say out

45:25

of all of them. So this penjavalis is

45:28

able to travel from your mouth to your

45:30

brain. It's only it's quite close by

45:32

anyway. And what's unique about this

45:34

bacteria is it's able to cross the

45:36

barrier between uh in your brain. So the

45:39

bloodb brain barrier um and it releases

45:41

these toxic enzymes. So these enzymes

45:43

are called gingipes and they're imagined

45:45

these like horrible firefighter things

45:48

and they can break down neurons. They

45:50

can break down um a lot of brain tissue.

45:53

And so when they looked at the cerebral

45:55

spinal fluid and the brain fluid or

45:57

tissue of Alzheimer's sufferers, they

45:59

found that 97% of them had these toxic

46:03

enzymes, these ginger pains in their

46:05

brains compared to zero for the patients

46:08

who did not have Alzheimer's. So this

46:10

is, you know, the first study shows,

46:12

yes, there's some sort of correlation,

46:13

but there's a lot of other risk factors.

46:15

The second one, which is looking at your

46:17

ginger pains, is showing that there's

46:18

definitely a strong causitive factor um

46:21

between the two. And then another study

46:24

which was very interesting was um

46:26

looking at cognitive cognitive decline.

46:29

So okay fine you have Alzheimer's

46:31

unfortunately um is it is it too late

46:34

should you stop brushing your teeth or

46:36

what's the point? And so what they did

46:38

was they had uh patients um who had

46:40

Alzheimer's and they checked their

46:42

cognitive function and they also checked

46:44

their oral health. And then uh six

46:46

months later they reviewed them and they

46:49

found that the patients who had gum

46:50

disease had a much more rapid cognitive

46:53

decline than those patients who didn't

46:55

have gum disease. So again, it is still

46:57

important if you do get Alzheimer's that

46:59

you maintain your oral health, that you

47:01

have someone help you brush your teeth

47:03

because your cognitive decline um will

47:06

be faster.

47:07

How do they unpick that from other

47:09

causal factors that might be going on

47:11

like bad food choices? Because in my

47:14

head I was thinking, well, if someone's

47:15

drinking sugary, fizzy drinks every day,

47:19

they're more likely to have gum disease,

47:22

but maybe also that the chemicals within

47:24

that fizzy drink are impacting their

47:26

chances of dementia. Maybe they're also

47:28

someone that has an unhealthy lifestyle.

47:30

Maybe they're more sedentary. If they're

47:31

eating bad things, maybe they're more

47:33

sedentary. And maybe it's that that's

47:34

causing the rapid cognitive decline

47:37

versus the gum disease itself. Is it

47:39

possible to untangle all of this?

47:40

I mean, it is very difficult. I think

47:42

that for those types of things, you

47:44

either, you're right, diet, lifestyle is

47:47

super important and we know that

47:48

Alzheimer's is again multiffactorial. Um

47:51

I think it's really about the quantity

47:53

of patients that they check. So they

47:55

need to be looking at a huge number of

47:58

patients and they did um to check

48:00

whether or not there is a strong

48:02

correlation between them. Um, also going

48:06

back to the ginger pain study, so the

48:08

one about the bacteria that shows it

48:10

doesn't it's not diet or lifestyle or or

48:13

nutrition. It is a specific oral

48:15

bacteria that has traveled to the brain

48:17

and released these enzymes which are

48:18

then breaking down neurons. So there

48:21

there's definitely a strong positive um

48:24

effect.

48:24

That is um fascinating. It's really

48:26

really fascinating because dementia and

48:28

Alzheimer's still seem to be a bit of a

48:29

mystery. it is and and I work um with a

48:34

team for Alzheimer's and what they've

48:36

done similar to what you were saying is

48:38

that they've kind of separated all of

48:39

the the causes of Alzheimer's that we

48:42

know um or the risk factors and

48:44

thankfully they've put oral health as

48:46

one of them as well and I think from all

48:49

of the other risk factors so uh you know

48:51

for example if you have uh the genetic

48:54

mutations you got the APO4 or any of

48:57

those mutations that's you can't change

48:58

that unfortunately some of us have

49:00

mutations which means that we are at a

49:02

much higher risk of suff of getting

49:04

Alzheimer's in the future. But something

49:07

like that oral bacteria p gingalis and

49:09

those gingi pains you can get rid of p

49:11

ging javalis really easily again if you

49:13

tested it you can even test for gingi

49:15

pains um and then you can get rid of the

49:17

bacteria before it starts causing

49:19

problems.

49:21

The test that you offer does it test for

49:22

gingi pains?

49:23

It does. Yeah. So, we're the only ones

49:25

um on the market who do because that was

49:27

something that I thought was super

49:29

important. What's the point in us

49:31

telling you that you have a bacteria if

49:33

we can't tell you that that bacteria is

49:35

being really bad in your mouth and

49:37

causing a lot of problems?

49:38

And people think I'm joking, but you

49:40

have actually tested several members of

49:41

my team, including myself. So, I am

49:43

actually going to find out the results

49:44

today. Um on the subject matter of the

49:46

brain, is there a link between my mental

49:48

health, depression, anxiety, and my oral

49:53

microbiome?

49:54

So again, there's been a lot of

49:55

research. Um I think it's difficult for

49:58

something like mental health and um and

50:03

gum disease, which you know, with the

50:04

chicken and the egg, which one came

50:05

first? Um because one of the issues is

50:09

if you have a decline in your mental

50:11

health, you are less likely to take care

50:12

of your oral health. um and therefore

50:15

that can exacerbate issues. So there has

50:17

been a lot of research to show that you

50:19

know

50:20

uh there's a correlation between poor

50:22

mental health and poor oral health. But

50:24

in my personal opinion that causitive

50:27

connection is not there yet. Um there's

50:30

also been some research with things like

50:31

schizophrenia, but again it's the jury

50:35

still in my opinion.

50:37

Are you able to tell the state of

50:39

someone's mental health by looking at

50:40

their oral microbiome in your view?

50:43

um you can know if something's up. Like

50:46

for example, I I had a patient

50:48

relatively recently. I've been treating

50:50

her for five, six years now, and I know

50:52

that she takes good care of her her

50:54

teeth. She she takes good care of

50:55

herself. And a few weeks ago, she came

50:58

in and she was not taking care of her

51:01

gums or her teeth at all. Everything was

51:02

an absolute mess in there. And um so I

51:05

did pull her aside and I was like,

51:06

"What's wrong?" Like something's

51:08

happened here. And I think it is quite a

51:10

big um sign for a lot of people. It's

51:13

the first thing that they kind of let go

51:14

of is their oral health.

51:17

And is that because of, you know, they

51:19

start certain self soothing behaviors

51:21

because they're stressed in other parts

51:22

of their life. So if they're having a

51:24

bad time in their relationship or work

51:25

and they're stressed, they might start

51:27

eating sugar more or

51:29

or just not brushing,

51:30

smoking or drinking more. Okay.

51:31

Or just not brushing. Like with this

51:33

woman, she just wasn't brushing her

51:34

teeth anymore. Another thing that we can

51:36

also see, I mean it's kind of a bit on a

51:39

tangent, but also um eating disorders as

51:42

well. So things like bulimia um or even

51:45

sometimes anorexia, you can see in the

51:47

mouth. So there's a lot of times where

51:48

we'll see young teenagers um and I'll

51:51

know that they are bulimic because they

51:53

have certain issues in their mouth which

51:55

they shouldn't have and that again is a

51:57

telltale sign.

51:58

Is that because the stomach acid is

51:59

coming through their mouth?

52:01

Yeah. So they get a lot of erosion on

52:02

the on their teeth and then in some

52:04

cases you can also get these marks on

52:06

the roof of your mouth. So if they're

52:07

trying to force themselves to to vomit

52:09

then you can see that. Um and that's

52:12

something that you know you have to pull

52:13

the patient aside or tell their mother

52:15

and explain that to them as well.

52:17

And is there a relationship between

52:19

stress and my oral health? So if I'm

52:20

more stressed and my cortisol levels are

52:22

higher, is that going to make everything

52:24

in my mouth worse?

52:25

Yes.

52:26

Even outside of the lifestyle choices I

52:28

might make in such a state.

52:29

Yes. just that stress will increase your

52:32

inflammatory markers, your inflammation.

52:34

Um, it also will dry your mouth out and

52:36

all of those things will be linked. Um,

52:39

uh, we do a lot of testing at my clinic

52:42

and so one of the tests that we look at

52:44

is collagen breakdown. So, um, we have

52:47

lots of different types of collagen all

52:48

over our bodies and our gums are made up

52:51

of a certain collagen. So we look at an

52:53

enzyme called ammpn and this enzyme is

52:56

responsible for breaking down that

52:58

specific collagen. Um so we test the

53:01

coll that enzyme all the time with our

53:03

patients. It's a really nice way of

53:05

knowing like um whether or not someone's

53:07

about to have gum disease. Um how much

53:09

collagen breakdown is happening from a

53:11

biomolelecular level. So I had a woman

53:14

very healthy, always been fine. Um and

53:17

then she had her collagen breakdown

53:18

tested and her levels were through the

53:21

roof. her gums looked fine. She didn't

53:23

look like she had any problems, but I've

53:25

never seen such a high level in my life.

53:27

And so, you know, I'm trying to think of

53:29

what could be causing it. All of that.

53:31

And she had lost her baby a couple of

53:33

days before. And that type of intense

53:37

stress on someone's body can have so

53:39

many effects and impacts on the rest of

53:42

your body. Um, and that was one of them.

53:44

When we retested her six months later,

53:46

she was back to normal again. But you

53:48

can see even your mouth, you know,

53:50

stress can really impact you.

53:52

On this subject, I was thinking about I

53:54

mentioned Jame James Nester earlier who

53:56

was telling me about the research of um

53:58

how the the mouth has changed shape

54:00

because of the foods we're eating and

54:02

how that that's caused a bunch of

54:03

downstream implications for us. One of

54:05

the also one of the other things he also

54:08

mentioned was about mouth breathing and

54:10

nose breathing. Yes.

54:11

And there's a lot of people that have

54:13

become incredibly interested in whether

54:14

we should be breathing through our

54:15

mouths or our nose. And I was wondering

54:17

if you had a perspective on that. Um,

54:21

and also the other thing that he

54:22

mentioned to me was that there's a link

54:24

between mouth breathing and things like

54:27

ADHD. What is your point of view?

54:30

Uh, completely agree with all of that.

54:32

So actually my sister, she is an

54:34

orthodontist. Um so she works at our

54:37

clinic and um we run it together with

54:40

our mother and um she is very very hot

54:42

on um mouth breathing. And what she um

54:47

mainly does is she basically tries to

54:50

stop children in particular from

54:51

breathing with their mouths open. And

54:53

what she has found is that most of her

54:55

patients um who come to her um are mouth

54:58

breathers. They often have some sort of

55:00

um ADHD. they have or some sort of

55:03

attention deficit. Um they are uh bed

55:07

wetters. They grind their teeth a lot of

55:09

the time. Um and they have a whole

55:11

cascade of other problems and uh she can

55:14

treat it then and it's relatively easy.

55:17

She would argue that it's very

55:18

difficult, but to me I think it's easy.

55:20

I'm like, "Yeah, there we go. You can do

55:21

what you do." Um and because the the

55:23

jaws of a child are very malleable, so

55:25

they haven't fully solidified, so you

55:27

can still move things. You can um get

55:29

the teeth to meet. So if you get the

55:30

teeth to meet correctly then uh the

55:34

child won't want to breathe with their

55:35

mouth open. The annoying thing is is

55:37

that uh a lot of adults are mouth

55:39

breathers because their teeth do not

55:41

meet correctly or their jaws are in the

55:43

incorrect position and uh at that point

55:46

it is quite difficult to move the jaws

55:48

into the correct position or to get the

55:50

teeth to close in a way so that the lips

55:53

are at rest and you breathe with your

55:55

nose instead of your mouth. But again, I

55:57

see those types of patients because they

55:59

all come to me with a lot of other

56:01

problems. So again, same thing. A lot of

56:03

them have uh a lot of them have suffered

56:05

from long COVID. A lot of them have

56:07

inflammatory conditions. Um are always

56:10

tired. They a lot of them chronic

56:12

fatigue. It you know there's a lot of

56:15

connections now uh between mouth

56:17

breathing and those types of issues as

56:18

well.

56:19

Is there a link between the health of my

56:21

oral microbiome and whether I breathe

56:23

through my nose or mouth? cuz James was

56:24

explaining to me that the nose is

56:26

effectively like a a filter system.

56:28

Yeah.

56:29

There's a certain temperature in there.

56:30

Yeah.

56:31

Um there's like sinuses and stuff which

56:33

are have some kind of mucus which helps

56:35

to catch bacteria. So if I'm breathing

56:37

through my mouth, am I more likely to

56:38

have unhealthy oral microbiome?

56:41

100%. So exactly the same thing. You're

56:43

you're you've got a filter in your nose

56:45

and so it will stop a lot of bad things

56:47

from coming through. But the mouth uh

56:50

there is no filter. I mean you breathe

56:51

it in, it goes straight into your lungs.

56:53

So, there's no way of stopping anything.

56:55

A lot of people now are starting to

56:57

mouth tape. Um, and that's become kind

56:59

of trendy and cool. Um, it's not the

57:02

easiest thing to do. If it seems a bit

57:05

weird to tape your mouth at night time,

57:08

um, but for anyone who's worried that

57:10

they breathe with their mouth open,

57:12

mouth taping, in my opinion, is a really

57:14

nice way of just like testing it out and

57:16

seeing whether or not you do breathe

57:17

with your mouth open because you'll do

57:19

some mouth taping and you can see

57:20

whether or not you sleep better. So, if

57:22

you have a wearable, you can see, "Oh,

57:23

wow. My oxygen levels are so much

57:25

better. I had such a deep sleep." And if

57:27

that's the case, you might be more

57:29

inclined to straighten your teeth or

57:31

sort out the reason that you're

57:33

breathing with your mouth open.

57:35

I I uh took notes of a study which kind

57:38

of is interconnected to the point we

57:39

were making about mouth brea breathing

57:41

which said in a six-year study of 11,000

57:43

children. It was found that children who

57:45

suffered from sleep disordered breathing

57:47

were 50 to 90% more likely to develop

57:50

ADHD like symptoms than were normal

57:53

breathers who breathe through their nose

57:55

correctly which is absolutely

57:57

staggering. 50 to 90% more likely to

58:00

suffer from ADHD like symptoms just

58:03

because they breathe through their mouth

58:05

at night and disordered breathing.

58:07

And it's it's mainly to do with also

58:08

oxygen being delivered to your brain,

58:11

right?

58:11

So there's not as much good oxygen um

58:14

like real rich oxygen, filtered oxygen

58:17

traveling to the brain and so that's

58:19

basically not allowing your brain to

58:21

function as well.

58:22

You mentioned kissing earlier on.

58:24

Yes.

58:24

Um I'm still supposed to kiss my

58:26

partner, right?

58:27

Yes. I hope you do many times.

58:29

You you said if I kiss her more than 11

58:31

times a day or something then our oral

58:33

microbiomes synchronize in some way.

58:36

Yeah. So there is um passage of bacteria

58:39

from you to her and her to you. Um they

58:42

have also shown that uh for example they

58:44

did a study where one uh partner chewed

58:47

lots and lots of probiotics or like good

58:49

bacteria and then had a super long

58:52

smooch with their partner and actually

58:55

was able to transfer nearly 60 or 70% of

58:58

that good bacteria into their partner.

59:01

So it's not necessarily longlasting. I

59:03

wouldn't say that um you know if you

59:05

kiss someone once on a night out that

59:07

you are going to terribly impact your

59:09

microbiome. it's fine. You can go and

59:11

kiss, but it's more for long-term

59:13

partners. If you're kissing regularly

59:14

and for a long time, then yes, your

59:16

microbiomes will start to um be quite

59:19

similar. Um, another factor as well is

59:21

that obviously your lifestyles are

59:22

probably pretty similar. You're probably

59:24

using the same toothpaste, eating the

59:26

same food. So, it's difficult to fully

59:28

put it on just kissing, but yeah.

59:30

What about oral sex and the implications

59:33

that will have? So, if we're if me and

59:35

my partner are doing oral sex on each

59:37

other, is that going to impact our oral

59:38

microbiome? Yes. So, actually there's

59:41

been a few case reports which have shown

59:43

um uh there's one in particular and I

59:46

had a patient as well who had this a

59:48

woman who um had a new partner and she

59:52

liked to perform oral sex on him and

59:55

then she came to me because she was

59:57

complaining of very inflamed gums and

59:59

she was getting gingivitis

60:01

and you know it's not something I really

60:03

ask like I'm not going to be like how's

60:04

your how's your sex life going these

60:06

days like so I didn't ask it but she

60:07

kept on coming back to me No, my gums

60:09

are still inflamed. No, my gums are

60:11

still inflamed. And then she asked, she

60:12

was like, "Is it maybe because I have a

60:13

new partner?" I was like, "Okay, maybe

60:15

you guys are kissing a lot." And she was

60:16

like, "No, no, no, no." And and then she

60:18

explained to me. Um, and then I was

60:19

like, "Okay, fine. Why don't you go and

60:21

test and ask him whether or not he has

60:23

any issues." Um, and it turns out that

60:25

he was having recurrent urinary

60:27

infections. And so, actually, they were

60:30

transferring bacteria and she was having

60:32

inflammation in her gums because she was

60:35

Yeah. performing her oral sex. So, yeah,

60:38

there is transfer. Again, I wouldn't be

60:40

scared and say never do it. Um, I once

60:43

made an ex-boyfriend do an oral

60:45

microbiome test uh just to check and

60:47

just to make sure everything was okay.

60:49

You made him do it.

60:50

Yeah. I don't It's not a It's not a um a

60:54

prerequisite anymore, but it was at the

60:56

time. I was like, "H, let me see. Let me

60:59

You must think that when you meet

61:00

people. You must think, God, I wonder

61:01

what their own microbiome is saying like

61:03

in a romantic context cuz you know the

61:05

significance of it."

61:06

Yeah. I think it's a, you know, I spend

61:07

a lot of time and energy making sure my

61:09

oral microbiome is very nice and

61:11

balanced. So, I wouldn't want anyone

61:12

messing that up for me. So, it's

61:14

important.

61:15

Are you in a relationship now?

61:16

Yes, I am.

61:16

Have you tested their oral microbiome?

61:18

I've been trying to, but he won't let

61:20

me.

61:21

You've asked him.

61:22

Yeah, of course I have.

61:23

And what did he say? Mind your own

61:24

business.

61:24

But I did give him an oral microbiome

61:27

test. So, hopefully he will just use it.

61:28

I said, "You can even use a fake name. I

61:30

don't care. I don't I'm not going to

61:31

test. I'm not going to check it. I just

61:33

want you to do the test for me.

61:35

For for you?

61:36

For me? Yeah.

61:37

And what's his what's his rebuttal? He's

61:39

like, I don't

61:40

He was like, what happens if you break

61:41

up with me if I have a really imbalanced

61:43

oral microbiome? And I was like, I hope

61:44

that our relationship is stronger than

61:46

just your oral microbiome. But there's

61:48

ways to fix it. And that's the beauty of

61:49

the oral microbiome is that it's

61:51

actually pretty easy to to fix and to

61:53

change.

61:54

If his results came back and he had a

61:56

terrible oral microbiome, one of the

61:57

worst you've ever seen.

61:58

Yeah.

61:59

Are you less likely to kiss him that

62:01

day? that day. Yes.

62:03

There you go. Don't do the test, my

62:05

friend.

62:05

No, no, no. Don't do the test that day.

62:07

Yes.

62:08

There's no upside to him doing this

62:09

test. I completely understand.

62:10

And then I would go and creep into his

62:12

bathroom and change all of his oral

62:14

products. This is what he's scared

62:15

about.

62:15

Personalize everything for him. And then

62:17

you've done that already.

62:18

I already have. He tests everything out

62:21

for me as well because I get a lot of

62:22

products sent to me. So, I'm always

62:23

getting him to to try things out for me

62:25

as well.

62:26

Okay. So, no if they've got um

62:29

issues down there.

62:30

Yeah. Okay.

62:32

And we don't really know if they've got

62:33

issues down there unless they admit it

62:34

or do some kind of test.

62:36

Yeah. Yeah.

62:37

Okay. What about fertility? Is there a

62:39

link between our oral health and our

62:40

fertility?

62:42

Yes. Um so if we look at men to start

62:46

with um there was a study done and they

62:50

found so they looked at a group of

62:52

subfertile men. So, men who um weren't

62:55

able to conceive with their partners and

62:57

they checked all of their mouths and

62:58

they found that over 90% of these men

63:01

had some sort of oral infection or

63:04

dental disease of some sort going on.

63:06

They split the group into two. Half the

63:08

group had the uh treatment that was

63:10

needed. So, I don't know if they had gum

63:12

disease or decay. They they got it fixed

63:15

and the other half were left to their

63:16

own devices. Um after eight months there

63:20

was a 70% improvement um in their

63:23

success for pregnancy. The men who'd had

63:26

their oral infection sorted um and they

63:28

had a much better improvement in their

63:30

sperm quality and motility as well.

63:33

And what did they do to those men in

63:34

that group where they saw the

63:36

significant improvement? So, for

63:38

example, if the man had um gum disease,

63:41

they would treat it with hygiene or if

63:44

they had an infected tooth, maybe they

63:46

would take it out or do a root canal or

63:48

etc. They would just have to treat that

63:49

infection. So, I speak a lot about gum

63:52

disease all the time, but actually

63:53

there's so many other oral diseases like

63:55

decay um or tooth a types of things that

63:59

can also contribute inflammation and

64:01

problems. In that study, 6 months after

64:03

that, their sperm had improved by 20%.

64:06

And after 8 months, 50% of their wives

64:08

were pregnant.

64:09

Yes.

64:10

That is staggering.

64:11

Yeah.

64:12

What about women though? Is is there a

64:14

similar sort of result as it relates to

64:16

women's fertility?

64:17

Yes. So, um research has also found that

64:20

if a woman has gum disease, um she is

64:23

less likely to ovulate. Um and also

64:26

she's going to have uh issues with

64:28

conception. So they found that women

64:30

with gum disease it takes them two

64:31

months longer to conceive versus a woman

64:34

who doesn't have gum disease. Um but

64:36

once the woman has conceived um the

64:39

issue is still not over. She still has

64:40

to maintain her gums. So firstly a lot

64:43

of women will have um pregnancy

64:45

gingivitis. So this is basically super

64:47

inflamed puffy gums because of all the

64:49

hormones. Um and so they should be going

64:52

very regularly to see their hygienist.

64:54

Um but also what the research has found

64:56

is that women who are pregnant and have

64:58

gum disease are at a much higher risk of

65:00

preterm birth so premature uh babies low

65:04

birth weight um and also preclampsia as

65:06

well. So they did a study in Malawi um

65:09

it was on 10,000 women. So Malawi has

65:11

the highest rate of preterm birth in the

65:14

world at just about I think

65:17

just under 20%. Um, and preterm birth is

65:21

a a big issue for for governments, for

65:24

hospitals. It's really expensive. You

65:26

need to keep the woman and the child in

65:28

the hospital for a lot longer, but also

65:30

that child will have a whole myriad of

65:32

problems afterwards as well. So,

65:34

weirdly, Wrigley's um the sugar the

65:37

chewing gum company sponsored this uh

65:40

study. They went to Malawi. They had

65:42

these 10,000 women. They split them up

65:43

into two. 5,000 of those women uh were

65:46

given sugar-free chewing gum,

65:47

toothbrush, and some toothpaste. And the

65:49

other half were left alone. And they

65:52

found that there was a 20% improvement

65:55

um or 20% sorry, reduction in preterm

65:58

birth in the woman who'd had the

65:59

sugar-free chewing gum compared to the

66:01

woman who hadn't had it. So something so

66:04

cheap and so easy like chewing gum was

66:07

able to actually reduce the risk of

66:08

preterm birth for these women.

66:10

How and why? So, if you look into the

66:13

research a little bit more, um you're

66:15

going to get your chewing gum now.

66:17

Yes.

66:18

Um so, sugar-free chewing gum um has

66:22

been shown to um stimulate your saliva.

66:25

So, it helps with what we were talking

66:26

about earlier, saliva is super

66:28

important, um and it provides all the

66:29

good food for uh your bacteria. Um but

66:32

then also, if it's sugar-free, um let's

66:34

say it's using xylitol, that's naturally

66:36

antibacterial, so it's killing a lot of

66:38

the bacteria in the mouth. And what they

66:40

found is that there are certain oral

66:42

bacteria that can travel down to the

66:44

placenta um and can also uh cause

66:47

problems there and essentially um

66:50

increase the chance of preterm birth.

66:52

You sufficiently convinced me that

66:53

saliva is an important thing and I

66:55

actually did one of your tests. Let me

66:57

go grab the results.

66:58

Okay.

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There may not be another one.

68:00

And here are

68:03

the results. Okay.

68:04

I've not actually seen them yet, so this

68:06

is exciting. Um, I'll give them to you

68:07

so you can explain them to me.

68:09

Okay.

68:09

Is that okay? So, this is the test that

68:11

I did, right?

68:12

Yes, you did. Yeah.

68:16

And the test I did contains

68:21

this little kit that basically in the

68:23

middle of the office one day, someone

68:24

came up to me and said, "Steve, can you

68:26

spit in this?" And I said, "Sure."

68:29

Yeah.

68:29

And then they took my spit away. Um, it

68:32

turns out it was upon request from you.

68:35

Yes, exactly. I wanted your saliva.

68:37

Yeah. Which is

68:37

just to check to make sure if I could do

68:39

this interview,

68:39

right? Okay.

68:41

So, this is the test that I did. I spat

68:43

in this little thing, sent it off back

68:45

to you. You ran the test. How long does

68:47

it take to do this test?

68:48

Uh, it would probably take you about 2

68:50

minutes to do spe yourself and then you

68:52

get the results three to four weeks

68:54

later.

68:55

What did you find out from doing my

68:57

test?

68:58

Well, okay,

68:59

let's go through your results. So um we

69:02

found that you have quite a diverse

69:04

microbiome. So that means that you have

69:06

a nice ratio of good bacteria versus bad

69:10

bacteria and this has been compared to

69:12

healthy and diseased subjects. So you

69:14

are really right on the top of the bell

69:16

curve. So very good with that. So happy.

69:19

Um then we predict your

69:21

diverse is better.

69:22

Uh arguably yes. Yeah.

69:23

Okay. Um then what we have is we've

69:26

created this algorithm that predicts

69:28

your risk of certain um issues or

69:30

diseases in the mouth. So those are

69:32

things like bad breath, gum disease, um

69:35

decay and general inflammation.

69:37

So your risk of bad breath was low. You

69:40

didn't have a high risk for that. Gum

69:43

disease was medium. So slight maybe

69:45

there's a bit of inflammation going on

69:47

there. Your risk for uh decay was also

69:50

medium. And your risk for general

69:52

inflammation. So this is inflammation

69:54

throughout the rest of your body. Um was

69:56

quite low. Um and then if we zoom in, we

70:00

then look at your good bacteria. So

70:02

we're also quite unique because we

70:05

thought that it was unfair that a lot of

70:06

tests don't look at the good stuff. So

70:09

we look at all of the bacteria which has

70:10

been shown to be the most beneficial in

70:12

the microbiome. So for you, you had

70:14

pretty much high to very high levels of

70:17

uh good bacteria, which is great. Uh no

70:20

problems with that. And then we look at

70:22

bad bacteria. So we actually uh look at

70:26

about 500 different bacteria, but then

70:28

we zoom into the top 20 bad ones which

70:31

are really associated with things like

70:33

gum disease, decay, bad breath. So for

70:35

you, out of all the bacteria that we

70:37

looked at, you only had quite high

70:39

levels of one bacteria which was bad for

70:41

you. Um and so this bacteria is very

70:44

strongly associated with basically a lot

70:47

of buildup of um plaque in your mouth.

70:50

So, having not looked in your mouth, I

70:53

have no idea about your dental health or

70:55

anything like that. I would assume that

70:57

basically um you're a bit overdue on a

70:59

hygiene. Maybe maybe there's a lot of

71:00

plaque buildup going on um from that

71:03

result. But the rest of the bad

71:05

bacteria, so all of these ones we're

71:06

talking about,

71:07

the erectile dysfunction,

71:08

your erectile dysfunction ones fine. Um

71:10

your pen javalis is fine, you know,

71:13

fucleatum, those ones were actually uh

71:15

very good. Um then also on top of that

71:19

going back to the Alzheimer's. So we

71:21

look at those virolence factors

71:22

associated with punjavalis and you had

71:24

none of those virilence factors which is

71:26

also really good.

71:28

Okay.

71:29

Then we look at your genetic mutations.

71:31

So uh we've identified about 10

71:34

different genetic mutations which

71:35

increase your risk of decay and gum

71:37

disease. So uh for the decay out of the

71:41

five genetic mutations we looked at four

71:43

out of five of them you hatch. So that

71:45

means that you and maybe you you have

71:48

stopped it, but you are at a higher

71:50

chance of having a sweet tooth, of

71:52

having more acidic saliva. On top of

71:55

that, it might be that you if you're

71:57

stressed out or you're really unhappy,

71:59

some people will run to the casino,

72:02

others will run to the bottle. And for

72:04

you, you might actually be someone who

72:05

goes and has a chocolate bar and

72:07

actually enjoys sugar.

72:08

No comment.

72:08

Um, on top of that,

72:10

make your business.

72:12

Let's say you've had your sugar because

72:13

you are stressed out or whatever. You

72:16

also have been shown to have a genetic

72:18

mutation which means that your taste

72:20

perception is lower. So you need two

72:22

bars of chocolate, not just one.

72:24

No comment

72:25

to make you feel

72:26

That's the end of this podcast.

72:27

That's the end of this episode. I'll

72:28

give you my card.

72:32

Close your document. How dare you?

72:35

No, I mean it all it all squares with

72:37

reality. So please do keep going.

72:39

Um so that's your decay. uh situation in

72:42

terms of gum disease. Again, we look at

72:45

um certain mutations. So, there are some

72:47

mutations that can triple your risk of

72:49

gum disease. Um they can increase the

72:52

amount of inflammation that you release

72:53

from your mouth. So imagine um you there

72:57

are some people who even the smallest

72:58

amounts of bacteria they might have

73:00

great hygiene they have a few small bad

73:02

bacteria in their mouths they have

73:04

mutations which means that they respond

73:05

in a very hyperinflammatory and very

73:08

aggressive way and they will be at a

73:10

very high chance of gum disease. So in

73:12

your case um you had one mutation and I

73:17

would say out of all of the mutations

73:19

for gum disease it was the best one. So

73:21

it basically means that you have um

73:24

genetically you're more predisposed to

73:26

bacteria collecting around your gums.

73:28

Okay?

73:28

So you might be someone who actually

73:30

needs to go really regularly for a

73:32

hygiene and it's kind of a bit annoying

73:33

because you keep on getting build up or

73:35

they keep telling you to come back

73:37

because actually genetically you have

73:39

that in your saliva.

73:40

Mhm.

73:41

Um then afterwards we give you

73:43

personalized recommendations. So, we

73:46

tell you based on um everything that

73:48

we've seen, the bacteria, your

73:49

mutations, what your input from the

73:51

questionnaire, we tell you what

73:52

toothbrush would be good for you, what

73:54

supplements you should be taking, what

73:56

uh toothpaste, floss, um everything

74:00

basically, even chew sugar-free gum, all

74:02

of those types of things to um improve

74:04

your oral health and rebalance your

74:06

microbiome.

74:07

And you could tell all of that just from

74:08

me spitting in a tube once.

74:10

Yes. And then at the very end, we have a

74:13

list of all of the detected organisms.

74:15

So, like I said, we look at the top 20,

74:17

which we know are really bad for you,

74:18

but actually sometimes in some patients

74:20

will have like weird bacteria, really

74:23

high levels of weird bacteria. So, I had

74:25

one patient, she had really bad breath

74:27

and her gums were kind of okay, her

74:29

teeth were okay, there were no problems,

74:31

but she was like, I don't know what's

74:32

going on. So, she did the saliva test

74:34

and she had 40% of her oral microbiome

74:37

was made out of one bacteria. So, uh I

74:40

was searching this bacteria. I was like,

74:42

I've never heard of this bacteria

74:43

before. It is extremely prevalent in

74:45

dogs. So then I get back to her. I'm

74:48

like, "Do you have any dogs?" And she

74:49

was like, "Yeah, yeah, I have four four

74:50

or five dogs at home." And I was like,

74:51

"Do you kiss your dogs?" She was like,

74:53

"Yeah, of course I do. Like they're my

74:54

they're my babies." So she was kissing

74:56

her dogs and she was getting transfer of

74:58

bacteria from her dogs into her mouth

75:00

and that was what was making up her

75:01

whole microbiome.

75:02

And that was giving her bad breath.

75:04

Yeah. Yeah.

75:04

So what I did was I gave her um a

75:08

treatment recommendation

75:10

and no I gave all of her dogs I said you

75:12

need to take the specific um it's not

75:14

medication it's like a supplement so it

75:16

basically stops uh like buildup of

75:19

plaque in dogs teeth. So I was like your

75:21

dogs have gum disease basically so they

75:23

need to be treated if you wants to get

75:25

better. And after everyone got treated

75:27

her bad breath went and so did her dogs

75:30

as well. Uh, so are dog owners more

75:33

likely to have bad breath?

75:35

If you are smooching your dog then,

75:37

yeah, kind of. And your dog has gum

75:39

disease.

75:39

If you're kissing your dog.

75:40

Yeah.

75:40

Okay. Interesting. So, what are the very

75:45

having seen my results, but generally

75:47

from seeing the thousands and thousands

75:48

of results that you've seen?

75:49

Yeah. What are some of the the easiest

75:52

things that I could do to help correct

75:55

that situation and have perfect oral

75:57

health and a perfect oral microbiome?

76:00

So, um, what we've done is if you were

76:03

to do the test, you would have all of

76:04

the personalized recommendations for

76:06

you. So, we tell you to have green tea,

76:08

to have honey, all of those types of

76:09

things which have been shown um through

76:12

research to benefit your microbiome in

76:15

your case specifically. But if we were

76:18

just talking about someone who hasn't

76:19

done the microbiome test and wants to

76:21

just make sure that they have as

76:23

balanced of a microbiome as possible, um

76:26

diet is obviously very important. So,

76:28

what we're talking about that sugar

76:29

attack, making sure that you only have

76:31

one sugar attack a day. Um you're not

76:33

having sugar consistently because it

76:35

does alter your saliva um pH. Uh the

76:38

type of toothpaste that you're using. I

76:40

like to keep it simple. You don't need

76:41

to we don't need to make things super

76:43

complicated. You don't have to spend

76:44

that much money. Having the right

76:46

toothpaste, right toothbrush, and the

76:48

right floss is honestly as much as is

76:51

the most necessary thing that you need.

76:54

Okay. So, in terms of brushing though,

76:56

you give some sort of practical advice

76:58

around when we should brush.

77:00

Mhm.

77:00

What is that? And is there any time

77:01

where I shouldn't brush my teeth?

77:03

Uh, you should never brush straight

77:05

after anything acidic or sugary. So,

77:07

what you end up doing is is grinding the

77:11

sugar or the acid into your teeth.

77:14

So, actually, you should wait 30 minutes

77:16

until you brush your teeth.

77:17

That's interesting because when I eat

77:18

something sugary, I feel like I need to

77:20

brush my teeth to get rid of it.

77:21

Yeah. No. No. So, you want to wait 30

77:24

minutes. So, instead, you can chew some

77:26

sugar-free gum or um there are lots of

77:29

pastals that we use. So, like I use like

77:30

chewable mints um and you can chew one

77:33

of those and it will actually neutralize

77:35

your saliva really quickly so that you

77:37

don't have that acid causing the

77:40

demineralization. And do I spit or do I

77:43

rinse after I've brushed my teeth?

77:45

Spit. So, you should never rinse your

77:46

mouth out with water after you brush

77:48

your teeth. So, brush, brush, brush,

77:50

spit into the basin, and that's it.

77:52

Reason being, again, going back to my

77:54

sunscreen analogy. Um, imagine you spend

77:56

2 minutes putting all this lovely

77:58

sunscreen all over your skin to then

78:00

just go and have a shower right before

78:02

you go into the sun. So, with the

78:04

toothpaste, you you spend 2 minutes

78:06

putting all of that on your teeth. And

78:08

then if you rinse it, then you're

78:09

actually removing all of that goodness

78:11

from your teeth and gums, and it's kind

78:13

of like you haven't done anything.

78:15

Toothbrushes.

78:16

Yes.

78:17

Which toothbrush should I use? This one

78:19

or an electric one?

78:21

Um, I generally prefer an electric

78:23

toothbrush.

78:24

Um, usually they kind of do the work for

78:27

you. So, it just means that patients

78:30

have better oral health because most

78:32

people don't know how to brush their

78:33

teeth properly. Actually, we're never

78:35

really taught or trained or we get

78:36

taught by our parents. Our parents don't

78:38

really know. They've been taught by

78:39

their parents. So, a lot of people don't

78:41

actually know how to brush their teeth.

78:42

Number one. Number two, we often don't

78:45

brush for as long as we think that we

78:46

are. So, we're meant to brush for 2

78:48

minutes. The average is 20 to 30

78:51

seconds. And we think that we're

78:52

brushing for 2 minutes, but we're not.

78:54

So, with an electric toothbrush, it

78:55

times you and then also a pressure

78:57

sensor. So, the electric toothbrush

78:58

often will have a pressure sensor which

79:00

will show you whether or not you're

79:01

brushing too hard or you're brushing at

79:03

the right pressure and that will reduce

79:05

your chance of recession.

79:07

Can you show me on one of those tooth

79:08

models in front of you the area of the

79:11

mouth and teeth that people most often

79:14

overlook?

79:15

Yes.

79:16

Can I have your teeth?

79:19

So, I would say the area that people

79:21

usually um struggle with the most is the

79:24

insides of their very back bottom teeth.

79:26

So inside where next to my tongue

79:28

basically. Yeah. Just near your tongue

79:30

basically. What a lot of people will do

79:32

is they'll kind of they'll go on the

79:34

inside and they brush their teeth like

79:35

this. Okay. Whereas actually you want to

79:37

get your elbow up and you want to brush

79:40

a lot more at like a a 90° angle when

79:42

you're getting there.

79:43

It looks like you're brushing the gums a

79:44

little bit.

79:44

A little bit. Yeah. So you actually do

79:46

want to brush the gums a little bit. And

79:47

then when we're on the outsides of the

79:49

teeth, uh we want to kind of brush at a

79:51

30° angle. So rotational movements and

79:54

at a 30° angle. So, not straight like a

79:56

90°, but kind of towards the gum margin.

79:59

And by doing circular mo movements,

80:01

we're essentially kind of massaging the

80:03

gums and getting rid of the bacteria

80:04

from under the gum and then flicking it

80:06

out.

80:07

Okay.

80:08

Yeah. So, just like that. And then I

80:10

always tell everyone it's really

80:11

important to kind of have um a method

80:14

behind your toothbrushing. So, don't go

80:15

like brush and then go there and then up

80:17

there and you know cuz you'll never

80:19

brush properly. Um, so always start,

80:21

let's say, on the left hand side, go do

80:23

all the outsides and then do all the

80:24

biting surfaces and then do all the

80:26

insides and then do the same on the top

80:28

teeth as well.

80:29

And that model there, you've got another

80:31

model in front of you which is like a

80:32

see-through model. What does that show

80:34

us?

80:35

Um, so this is to show you um what an

80:38

implant looks like. A lot of people

80:39

don't know what implants look like um

80:41

and how it looks like if it was within

80:42

your jaw.

80:43

Also what all the roots look like. And

80:45

then also if you look on the other side,

80:47

you can see um this tooth which has the

80:49

black within it.

80:50

Yeah.

80:51

Um and it's got like a red bubble at the

80:52

root of it. So this is a tooth that's

80:55

had a root canal done to it and has an

80:57

infection at the root of that tooth. So

80:58

that's an abscess. Um and a lot of

81:00

people don't actually know what that

81:02

looks like. Um they only feel toothache,

81:04

but this is what toothache is actually

81:06

in their jaw.

81:07

When our teeth get teeths, is that the

81:09

right word? Is that a plural? When our

81:11

tooths, what's the plural of teeth? It's

81:13

teeth. Is it teeth? Yeah.

81:14

Yeah. When our teeth get stained,

81:16

yes,

81:16

what we often do is we'll take some sort

81:18

of whitening toothpaste or we'll go to a

81:20

a dentist or a hygienist or something

81:22

and ask them to whiten our teeth.

81:23

Now, I've always been a bit scared of

81:25

that because there must be a cost to

81:28

this whitening industry. Should we be

81:30

whitening our teeth? Is there any

81:32

healthy way to whiten our teeth?

81:34

Yes. Um, so you've got two different

81:38

types of staining. One which is

81:39

extrinsic. So that's basically your

81:41

coffee, your tea, your smoking. super

81:43

easy to get rid of. Um you just have to

81:45

go to your hygienist and get a hygiene

81:47

done and they'll get rid of the stains

81:48

um pretty quickly. Um or you can try a

81:51

whitening toothpaste. Be very careful

81:53

with a lot of those whitening toothpaste

81:54

because they can be quite abrasive and

81:57

damage the enamel actually. So it's kind

81:59

of like exfoliating your teeth, but your

82:01

teeth don't grow back. So if you keep on

82:03

exfoliating and and getting rid of that

82:05

surface layer of enamel over a long

82:07

amount of time, that can be quite uh an

82:09

issue and quite problematic.

82:10

You get sensitive teeth. Yeah, sensitive

82:12

teeth and then the underlying um tooth

82:14

will start to shine through and that's

82:16

quite yellow. So, you actually start

82:17

ending up doing the the opposite of what

82:19

you wanted to do. Um then whitening. So,

82:22

you could you should do that

82:23

professionally. Um don't go and buy some

82:26

over the counter online thing. Um

82:28

because a lot of the time either they

82:30

don't have the the right percentages and

82:32

they can actually damage the teeth and

82:34

the gums uh really badly. So, you want

82:37

to get that done professionally. um if

82:39

you get it done by a good brand and even

82:41

within the professional world there are

82:43

some whitening um products out there

82:45

which are really bad for the teeth and

82:47

others which are actually really good

82:48

for the teeth. So we use one in

82:50

particular um it's called a niton and uh

82:53

the whitening for one day is the

82:56

equivalent of having a Coca-Cola. Um so

82:59

thinking about it I mean I'm sure

83:01

everyone has had one Coca-Cola in their

83:02

life. Having a Coca-Cola every day for

83:05

let's say five or six days is okay in

83:07

the grand scheme of things. is not going

83:09

to massively damage your your teeth at

83:10

all.

83:11

Okay. So, there is safe ways to do it.

83:13

Okay, good. And is there any way to

83:14

remove plaque yourself without having to

83:16

go to a dental hygienist?

83:18

Um, so you can try a water flosser. Um,

83:20

I've just bought one of those things,

83:21

but it doesn't feel powerful enough cuz

83:23

when I go to the hygienist, I don't know

83:25

what they're using, but it like it like

83:27

it's so strong.

83:29

Yeah.

83:29

That it like blasts my mouth off. My

83:31

mouth feels so different after.

83:33

Yeah.

83:33

And I wanted to know if I could buy one

83:34

of those for my home,

83:36

but I think it's a little bit dangerous.

83:37

Um well the reason I think that the

83:39

water flossers are not that high

83:41

intensity is because people can um

83:43

damage their teeth if they don't use it

83:45

correctly. So kind of no there are some

83:48

supplements that you can take to reduce

83:50

the amount of plaque that builds up um

83:53

and that actually does work quite

83:55

effectively.

83:56

I mean what are you there are two more

83:57

there there's a couple more things there

83:58

that you have in your pile that we not

84:00

talked about.

84:00

These are probiotics.

84:01

Okay.

84:02

So going back to our microbiome uh

84:04

probiotics are basically good bacteria.

84:07

So, um, not everyone needs them, but a

84:09

probiotic, uh, essentially will, uh, put

84:12

good bacteria into the microbiome, and

84:14

if it's got the right environment to

84:16

live in, then it will continue to grow

84:18

there. Basically,

84:18

if you're eating the right things,

84:20

Exactly. If you're eating the right

84:21

things, you've got prebiotics, you're,

84:22

you know, all of those types of things,

84:24

then, then this will be really

84:25

effective. So, these are two different

84:26

options. This is a mouthwash. Um and

84:29

again on the microbiome test that we've

84:31

created or Alice one um we look at all

84:34

the levels of good bacteria and then

84:35

we'll recommend a probiotic based on

84:38

what good bacteria you are missing. So a

84:40

lot of us are actually genetically we've

84:42

been born without certain good bacteria

84:45

in our microbiomes and so this is really

84:47

lovely to supplement them. So this is um

84:49

it's a mouthwash but it's in a powder

84:51

form. So, you take a teaspoon, you mix

84:53

it with some water, and that activates

84:56

the probiotic, and then you rinse it

84:58

around, um, and you swallow it. So, it's

85:00

a kind of a twoin one for your gut. This

85:02

is a pill, so it's a tablet. You chew

85:04

it, um, and then you can swallow it. So,

85:06

this is again, this is super easy, too.

85:08

Um, and and I love these as well. Very

85:10

easy to use.

85:12

Victoria, what's the most important

85:14

thing that we haven't talked about today

85:15

that we should have talked about today?

85:17

Uh the only thing that I think you

85:20

haven't mentioned that your viewers

85:21

might benefit from is the use of straws.

85:23

Straws are very very important to to use

85:26

um for sugar and also for acid. So

85:29

drinking through a straw actually helps

85:30

you bypass um all of your teeth. So if

85:33

you're having something acidic or really

85:35

sugary or even something staining, then

85:38

it bypasses the teeth and goes straight

85:39

to back of your throat so you can

85:41

swallow it. Um so this helps reduces

85:43

your chance of decay of tooth wear and

85:45

also staining as well. But specifically

85:47

if it's bad for you because you I'm sure

85:49

there's some things which are good for

85:50

the oral microbiome that you do want to

85:52

be in the mouth.

85:53

Yes. Yeah. Yeah. So if you're taking

85:54

your probiotics or whatever then of

85:55

course those are great. Um like for

85:57

example um you know I'm human. I like a

86:00

nice Coca-Cola once in a while and I'll

86:02

drink it through a straw. Um or if I

86:04

have alcohol I'll also drink that

86:06

through a straw as long as it's not

86:07

wine. But

86:08

about smoking and vaping.

86:11

Um so yeah smoking and vaping. Neither

86:13

of them are good for the oral

86:15

microbiome. Um it goes back to um dry

86:19

mouth. So smoking will dry your mouth

86:21

out and then you don't have the saliva

86:22

and the saliva can't do what it wants

86:24

to. It stops um vascularization. So it

86:27

stops blood flow to your mouth. And so a

86:30

lot of uh smokers actually will not have

86:33

bleeding gums. That doesn't mean that

86:34

they don't have gum disease, but because

86:37

they um are smoking so much, the blood

86:39

vessels are already really tight and

86:41

constricted from the nicotine. Um so

86:43

they don't ever get bleeding gums even

86:45

though they have gum disease. Um and

86:48

then the third thing is that actually we

86:49

know that smoking is very strongly

86:51

associated one of the biggest risk

86:52

factors for gum disease.

86:54

If someone's now curious about their own

86:57

microbiome and the work that you're

86:59

doing what is the sort of easiest entry

87:02

point to learn more to get themselves

87:05

checked or to I don't know to resolve

87:07

some of the issues that are causal or a

87:10

consequence of having an unhealthy

87:11

microbiome. Where where do they start?

87:12

How do they find you?

87:14

We have a clinic in central London

87:16

called the Health Society. Um we opened

87:18

about a year and a half ago now. And our

87:20

aim was to put their mouth back into the

87:23

body to explain to patients exactly

87:25

what's going on in their mouth. And we

87:27

can do that through microbiome testing,

87:29

other saliva tests. Um we look at your

87:32

blood glucose levels, your vitamin D

87:33

levels. We've got packages. We have an

87:35

infrared sauna. We have a nutritionist.

87:37

And the idea is that we're working all

87:38

together because one of the issues I was

87:41

seeing was that patients, they want to

87:43

understand what's going on in their

87:45

mouth and they want to optimize it, but

87:47

they don't understand a lot of what

87:49

dentistry is all about. We used to live

87:52

in a world where the dentist would say,

87:53

"Okay, you need two fillings and you've

87:55

got gum disease and you're not brushing

87:56

your teeth." And that was the end of it.

87:58

And you would just listen to them and

87:59

you get your work done. But now we are

88:01

trying to essentially decode dentistry

88:05

and explain it in a way that patients

88:07

can understand. So I would say I'm

88:08

biased but come over, come to the

88:10

clinic, we can explain everything. Um or

88:12

you can do an oral microbiome test and

88:14

you can actually understand yourself

88:16

what bacteria, what genetic mutations

88:18

you have, what inflammation you have,

88:19

what products you should start using and

88:21

then based on that decide on what

88:23

dentist you want to go to for any

88:25

treatment if needed.

88:26

What if I'm in Australia or Canada or

88:28

New Zealand or America? what can I do?

88:30

Um, so we're actually rolling out the

88:31

oral microbiome test to all of those

88:33

countries. Um, so you can actually buy

88:35

at the moment uh through that. Uh, you'd

88:38

have to email us, but otherwise that,

88:40

you know, I'm not the only one. There

88:41

are other people who are doing this type

88:43

of dentistry um, and are thinking in

88:46

this type of way. So, you would have to

88:48

do a little bit of research, but um, I

88:50

guess maybe follow me on Instagram and I

88:52

can give some top tips. I'll I'll link

88:54

all your your website, your social

88:56

channels below, and if anyone wants to

88:57

send you an email, you might get a

88:58

couple of emails warning you now. Um, so

89:02

you got to be careful what you wish for,

89:03

but but I'll I'll put all those details

89:05

below. Um, we have a closing tradition

89:07

on this podcast where the last guest

89:08

leaves a question for the next guest,

89:10

not knowing who they're leaving it for.

89:12

Okay.

89:12

And the question that's been left for

89:14

you is, what is the most important

89:17

relationship in your life and why?

89:21

Um

89:22

this is going to cause you problems.

89:24

Yeah, I know. So

89:26

um I would say um my mother I think that

89:30

is the most important relationship for

89:33

uh me. I think she um has been uh one of

89:37

my biggest mentors. She's been my

89:39

biggest cheerleader, my supporter. Um

89:41

she's hard on us, but that has led to me

89:45

being the person that I am. Um, and I

89:47

think that if I don't have a good

89:49

relationship with her, um, then I can't

89:52

have a good relationship with other

89:54

people. She's taught me respect. She's

89:55

taught me how to, you know, handle

89:57

myself around people. Um, so yeah, I

90:01

guess, uh, big up to my mom.

90:02

Is she Is she Iranian?

90:04

She is. Yeah,

90:04

she's Iranian. Yeah. And your father?

90:07

He is French American.

90:08

French American. And if we sit here in

90:11

10 years time, what are you hoping the

90:13

world looks like as it relates to the

90:14

oral microbiome, people's understanding

90:16

of it, the the regulations? What are you

90:18

hoping for? If you could wave a wand.

90:20

I am hoping that um the mouth is put

90:24

back into the body in the sense that

90:26

dentistry and medicine are fully

90:27

integrated within each other. So you can

90:29

go to your dentist and you can get a

90:31

saliva test and that could flag up

90:33

issues with your heart or diabetes and

90:36

you will go and see your diabetist. Um

90:39

and we link everything together. Uh also

90:42

my other dream is that people start

90:44

testing their saliva and they understand

90:46

that you know blood is not the only way

90:48

that we can understand things that are

90:49

going on within our body.

90:52

Dr. Victoria Samson, thank you so much.

90:54

Uh, I find this so unbelievably

90:55

fascinating in part because I've never

90:58

heard about any of this stuff before.

90:59

And I I do this job, you know, I've done

91:01

it quite a few times now. So, I've

91:02

spoken to a lot of health experts that

91:04

talk about the brain or I don't know,

91:06

infertility or um the gut microbiome,

91:09

but never one that looks at the body and

91:11

our overall picture of health through

91:13

the front door or the lens of our oral

91:16

microbiome. And so, it's really really

91:17

inspired me. And I think sometimes on

91:19

this podcast, I just love having these

91:20

conversations because sometimes it you

91:22

just need a little bit more information

91:23

about the importance of something to

91:26

make even a small change in your life.

91:28

And as it relates to our microbiomes,

91:30

our oral health, um our brain health,

91:32

and all of these things, even a small

91:34

change can have a big downstream impact

91:37

when we're talking about areas of our

91:38

health where things compound over time

91:41

and can either compound for us or

91:43

against us. And so, thank you so much

91:44

for doing the work that you do and

91:46

shining a light on this. work has been

91:47

really seinal in sort of driving the

91:49

conversation but also turning the lights

91:50

on to to the state and importance of our

91:53

oral health and I'm sure that if we sit

91:56

here in 10 years time you would have

91:58

impacted many many many millions of

92:00

people um and their overall picture of

92:02

health through the lens of the oral

92:04

microbiome because of the work you're

92:05

doing and the message you're putting out

92:06

there and that is quite something. So

92:08

congratulations well done and thank you.

92:10

Thank you so much. Thanks.

92:14

probably shouldn't be sharing this yet,

92:16

but you are our Diary of SEO community.

92:18

So, I wanted to give you a small first

92:20

look at a product that we're about to

92:22

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92:24

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92:27

one of the most uttered phrases in the

92:28

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92:32

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92:34

that has absolutely changed my life. And

92:36

if you ask me, it is the reason that

92:38

this podcast has grown in the way that

92:40

it has. By understanding the power of

92:43

compounding 1%s, you can absolutely

92:45

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92:47

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92:49

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92:52

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92:55

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92:57

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93:03

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93:07

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93:13

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93:15

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93:18

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93:20

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93:21

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93:23

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93:24

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93:26

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93:29

that is the diary.com.

93:32

[Music]

93:35

Heat. Heat. N.

93:36

[Music]

93:52

[Music]

Interactive Summary

Dr. Victoria Samson discusses the groundbreaking research linking our oral microbiome—the second largest and most diverse in the body—to our overall systemic health. She explains how an imbalanced oral microbiome can lead to, or exacerbate, severe conditions like heart disease, diabetes, Alzheimer's, rheumatoid arthritis, and even impact fertility and cancer progression. Dr. Samson emphasizes that the mouth is a gateway to the rest of the body and that proactive oral health management is essential for long-term well-being.

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