I have so many of my friends that just

literally have everything except their

health and I just don't want that. You

know, there's a limited amount of time.

I'm not trying to live forever. I'm just

trying to live well. So, this week I'm

going to explore some questions that I

have about my health and I suspect that

many people out there have about theirs.

>> That's great so far.

My father lived a really unhealthy life.

He struggled with alcoholism for

decades. He was diabetic. He had heart

issues. And in the end, he died of a

cardiac arrest. We were expecting his

death, but he still left my mom, my

siblings, and me, honestly, to pick up

the pieces.

When my friend Dave died of a heart

attack, I wasn't expecting it. To me, he

seemed perfectly healthy and that was my

real wakeup call.

We were in Mexico and he had a heart

attack and it was a real tragedy to be

totally honest. But on the heels of

that, his wife asked his four best

friends just to like really try to, you

know, take care of ourselves better and

specifically to start going and seeing a

cardiologist.

Hey, welcome back.

>> Thanks. It's great to see you.

>> It's great to see you online on X, we

saw some uh interest about statins.

>> So, Dr. Carlsburg, he is the best

interventional cardiologist in the

United States.

>> When he discovered some plaque in my

arteries, he put me on statins. They're

supposed to lower bad LDL cholesterol,

reduce the risk of heart attack, and

stabilize plaque. But to some they are

controversial.

>> Well, you posted basically trying to do

something

um for cardiac health across all of

America and you tagged me and Bobby, but

the amount of commentary in Twitter or

in X rather was all about the whether or

not I should be on a statin and whether

or not it was just completely um

pseudocience. Look, what I've learned in

my career is I could talk about

anything. I could say the sky is blue

and there will be opinions that say it's

not. So, to be honest with you, I kind

of ignored most of it except to say that

the few people who are very thoughtful

in there brought up, I thought, a very

legitimate question. A lot of my

followers feel like statins might help

them in some areas, but also hurt them

in others. That's one of the reasons why

I've been coming to Dr. Carlsburg so

regularly to help me figure all of this

out. What's the most difficult part of

doing all this testing, would you say?

>> To be honest with you, it's the

cognitive load before you start it

because I think there's so many

incentives. There's little voices inside

of many people's heads that says don't

even start because of what you could

find.

>> And I do this test every four or five

years called a CT angagram with

contrast. [music] It's basically a way

of injecting a die into your veins and

then imaging your heart so that you can

see all the arteries.

>> Breathe in. Hold your breath.

>> What it's also able to do now is image

it in such a way where you can take that

corpus of data and send it into a

machine learning model and then now you

can start to extract an even more

detailed sense of what's happening.

>> That young lady is a perfect study.

>> Absolutely beautiful.

>> I mean it's weird when the contrast goes

in your body.

>> Yeah.

>> Um I've had it done a couple times

before obviously

>> but I really I forget each time.

The heart is important, but it's only

part of the story. If you want a more

complete sense of your overall health,

you really need a prenal scan.

>> Good morning.

>> Hi,

>> how are you? Good. How are you?

>> Good, thanks. So, I reached out to

Chimath when we had just opened a clinic

in Silicon Valley during CO and I

thought I knew he was a bit of a hacker,

a biohacker, and I really wanted him to

experience what we were doing. He was

nice enough to come in. We developed the

friendship and he's been in for several

scans. Click. You [music] accept right

there.

>> In the 5 years since I met Chamath,

we've now imaged about 150,000 people.

We've saved or made about 4,000

life-saving diagnosis. And every day we

get stories from folks where we might

have saved their life or gave them

clarity or delivered peace of mind. So,

it's really great to be building a

company and at the same time having

positive impact.

>> Okay, let's do it.

So what makes us unique compared to

others is we operate our own customuilt

research grade MRI hardware. We have AI

that enables us to enhance image

quality. And then we have this

incredible team of radiologists and

medical professionals now over 100 that

deliver a tremendous [music] stand of

care for our patients.

So I just did a full body advanced MRI

scan. Took like an hour and 15 minutes.

But it really didn't feel that way cuz I

just was lying in the machine watching

Netflix. So, it's actually like a really

it's really great actually.

>> Okay. Yeah. So, we just got in the car.

We are uh headed to Toronto Tech Week.

>> Our first stop is at the Shopify

headquarters for a fireside chat with my

friend Farhan Thoir.

>> Good. How is the AI?

What's up?

>> Being on stage is something I like

because it allows me to tell people what

I think is going on right now and what

will go on. [music]

>> I hate to say it this way, but like the

more success that you can have, the

easier it is to detach yourself from

real life. And then you start to miss

out on people.

>> And if enough people, you know, find

that truth credible, some subset of

those people will self- select and say,

"Hey, I want to work with you on this."

And then I, you know, feed them into

those businesses. It's a great

opportunity for them. But it's also how

we get one step closer to achieving our

dreams.

>> Now, we're going to jump in the car and

uh go to the 8090 office and have lunch.

>> Yeah. Just trying to say hi. Good to see

you again. Good to see you.

[music]

>> Okay, let's talk because I don't want to

run out of time. So, what do we have

till 3:00?

>> What I found is that early on,

especially when you're trying to do

something extremely ambitious like the

8090 team is trying to do, the biggest

problem is drift. Meaning, you just kind

of drift away. Everybody just drifts

away. they lose an understanding

and I think the responsibility of the

CEO in that early phase when you're in a

build cycle is to minimize the drift.

The way that I think a [music] good CEO

can do that is just reminding people of

what they're there to do. And so, you

know, in Toronto is just a chance to

just take everybody and sit them down,

whiteboard something, just talk to them

so that they could feel a sense of what

was happening. It's one thing to hear it

on a Zoom or see it in slides, but it's

another to just be in the room and feel

that connection.

>> Super excited. Thank you guys.

[music]

>> Okay, so what's the plan today? We're

going to go and get a little readout of

the pre-nuvo scan. Um, and hopefully

everything is, you know, relatively

straightforward there. These health

tests may seem a bit like overkill, but

I feel strongly that people need to

advocate for their health and ask a lot

of questions.

>> What we know is that you lose about 3%

of your brain volume every decade on

average.

>> Is that right? [music]

>> Yeah. And so the question is, how do you

compare?

>> Honestly, my stomach fell a little bit

when Andrew mentioned brain volume loss

because I knew the FDA label on statins

warns about memory loss.

>> All right, Sean, over to you. Tell me

the good news or the bad news. So, um,

this [clears throat] is the enhanced

scan now. And so, what what we're

looking at here is just blood flow

throughout all the, uh, higher

functioning brain tissue. And this is

all very symmetric and normal.

>> Um,

>> well, I think what Dr. London is saying

is you're on a normal curve here.

>> Suck it, people. All the all the haters

out there.

>> Nothing worrisome, no change when it

comes to my brain. I'm really relieved.

But something that did confound me is

that I have some muscle loss, which is

concerning. This is the main thing I

wanted you to to focus on and to

highlight was the muscle the muscle mass

because we know how important

maintaining muscle mass is particularly

for you know brain health too over time

and it's [music] harder to maintain as

we get older.

>> Plus the internet internet thinks that I

don't work out that I should be doing

more leg day. So this is going to really

feed the [laughter] whole conspiracy.

>> I mean take everything with a grain of

salt too. You know like

>> they're going to love it.

>> I mean it it's not like a a terribly

concerning decrease. Yeah,

>> it was just it was just more notable

than the than the other uh fluctuations.

>> But the trolls are going to love it.

[laughter]

Like I told you, you don't work out your

legs.

>> It's not true, guys. I'm just tall. I

mean, every time I come, it just gets a

You're doing a better and better job

building this thing. It's so great. I

love being a guinea pig for stuff

[music] like this.

>> Yeah.

>> And it's been really valuable for me.

The next like 10, 11, 12 years. I really

want to make sure I pack as much muscle

as possible. [music]

>> Insulate myself going into my 60s and

70s. Seems like the right goal. Thank

you.

>> Thank you very much. Thanks for

visiting.

>> Great to see you.

>> Yeah.

>> Now it's time to check back in with Dr.

Carlsburg and face the music on my

heart.

>> Welcome back.

>> Thank you. Good to see you.

>> Uh you had a really busy day yesterday,

didn't you?

>> Busy day,

>> but a good day.

>> What I'm going to do now is present

something that's quite astonishing. You

have a zero calcium score and you still

have a zero calcium score.

>> Let's get out of here. [laughter]

Not so fast.

>> We see that over the 10 years you had a

370%

increase in that material, which means

that you are on a pathway to

atheroscerosis,

but you're one of the few peoples on the

planet that have this kind of

information

>> and you're going to take advantage of

it. And so what we're looking at here

was a percent change that went from

total plaque volume fell from 24% a year

to 10% a year, which is consistent with

what we found in much bigger studies.

Now, given the first level of tears,

which is listen to your audience and

come off the drugs because they're

dangerous, or stay on the drugs, the

first level of decision on your part

based on what you heard is going to be

what?

>> Obviously, we're going to stay on the

drug. So,

>> okay, that's your decision.

>> Yeah.

>> Okay.

>> I think what I'm hearing from you is

[snorts]

>> we started [music] this statin a decade

ago. It seems to have had a pretty

meaningful impact. we

>> in all of these other things that we

never would have known to look for had

this stuff not existed.

>> Exactly.

>> So, what I'm learning from you actually

is a big deal. You've done some good

stuff and that was actually pretty

preventative and good, but there's

[music] now an even better leading edge

for you because you're fighting against

a genetic trend that will eventually

catch up with you.

>> It that's a secret. That's fantastic. I

want to know the secret. I want to know

the answer. Now,

>> there are no standard treatments for

you. I think that you could choose to

wait. Your calcium score is zero. Your

[music] outcome is going to be fine for

the next 5, 10 years. Chances of you

having a cardiac event [music] are very,

very close to zero.

>> No risk of a cardiac event in the next

five years. Hopefully 10.

>> Uh that's my prediction. All right.

>> You're doing a great service. Thank you.

Thank you. See you soon. Have a great

summer.

>> Byebye.

You know, if there's one thing I've

learned through this process, it's that

there's no finish line. Honestly,

optimal health isn't a destination. It's

a journey. But at the end of the day, we

all face [music] the same choice. Do we

wait until something breaks or do we

start listening now? Starting [music]

the health journey can be scary. But in

my opinion, I think it's worth it

because living well is the best return

there is.

>> Well, we're home. It's been a long week.

I hope you enjoy following me around,

but now it's time to get the out of

here. [music]