The Anti-Obesity Doctor: If You Don't Exercise, This Is What's Happening To You! - Gabrielle Lyon
3228 segments
To this day, everybody focuses on
obesity, but obesity is not our problem.
If you are in the lower 1/3 of strength,
you have a 50% greater risk of dying
from nearly anything. You have to
prioritize skeletal muscle. What is
that? This is the organ of longevity.
The only organ system that you have
voluntary control of. And there's only
two ways to stimulate skeletal muscle.
Number one, Dr. Gabrielle Lyon is a
pioneer of muscle science and the
board-certified physician for athletes,
CEOs, and Navy SEALs.
Transforming the way we think about
muscle and how it can prevent disease,
optimize your body, and completely
reshape how we age. When it comes down
to your health, it shouldn't be about
how you look. It should be about how you
perform. And there's no replacement for
resistance training and skeletal muscle
mass. But, only 6 to 8% of people are
meeting the resistance training
guidelines, and the majority of
individuals are sedentary. Can you
describe to me what my life will look
like as a 61-year-old if I just sit in
this chair and do zero resistance
training for the next 30 years?
you ready? You're 30. So, right now,
Alzheimer's disease and cardiovascular
disease is likely. Throughout your
lifespan, your testosterone is probably
low, and your sperm quality isn't as
good as it could have been.
So, there's a link between my fertility,
for men and women, and my muscle mass.
Yes. And then, probably going to be
extremely winded walking upstairs.
Likely have obesity and sleep apnea,
which means you're deteriorating your
brain and metabolic health, and it's all
going to come down to choices. Our
present choices will determine our
outcomes. So, run me through your day
cuz I'm just going to copy whatever you
do. Great. Okay, so, what time do you
wake up? What do you eat? How long do
you train for? Are you calorie counting
at this point? And what time is that
last meal typically? Well,
Question. If you could sit at a table
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[Music]
Dr. Gabrielle Lyon.
What is it that you do for people?
I believe that I take away any physical
restrictions.
And I certainly feel privileged to take
care of people that change the world.
And when you say physical restrictions,
give me some flavor and color as to what
I mean.
Yeah, you know, when we think about the
way in which humans are,
sometimes they have low energy or
hormonal problems or gastrointestinal
problems, you name it, but those things
limit their ability to show up in the
world.
No matter how high-performing or how
high-achieving,
the common denominator is their health.
And nobody will ever go higher than
their own personal health. It is the
great equalizer, that and age.
And who do you do it for? Give me a
flavor of the people you've worked with
and the walks of life they come from and
what they do.
Well, I've been a physician for 20
years, and there has been a number of
patients and kinds from geriatrics. I
did my fellowship in geriatrics and
aging.
And when I finished that, I started a
concierge medical practice.
And I take care of, right now, many of
the guests who have been on this
podcast, like, um, Evy Poumpouras and,
um, yeah, woman named Danica Patrick. I
don't know if you know who that is.
She's a race car driver extraordinary.
And many Tier 1 operators, like Navy
SEALs and CEOs,
individuals that are out there that are
mavericks, really trying to change the
world.
And one of the things that happens is
individuals have this capacity to push
through any way that they are feeling.
But, the cost of that is very
predictable.
And in my clinical practice, and part of
what I believe that I was put on this
earth to do, is to help people who help
change the world.
So, when people come to you and your
practice, what is it that they typically
say? What is it that the most typical
thing that they're searching for and how
do they articulate that?
That is a wonderful question, and one of
the things that they say is they feel
like they know they could feel better,
that they could have more energy, better
sleep, you name it, that they just have
this sense that something is still on
the table.
And we figure it out.
We go through whether it's environmental
testing, again, hormones, blood work. A
lot of my patients have been deployed
overseas. They come back, they've been
to Mayo Clinic and all these other
places, but
they still don't get better. And I think
wellness and health is very holistic
in
the approach.
And I am telling you, once that is taken
care of,
these people
are already making such an impact, but
then they can go on because they're not
encumbered
by
inflammation or not feeling well, or
let's say their body composition is off.
Let's say they are someone who's always
been a high achiever and high performer,
I don't know, they hit midlife and all
of a sudden things have changed.
It's my job to help remove any of those
physiological restrictions so that they
can do what they do best and not worry
about the other things.
Is it complicated
what you propose? Are your solutions
complicated or are they simple?
Another great question. It really
depends on what it is that we're looking
at.
The most complicated
of all of it is actually not the
physical.
It is definitely the mental.
Because you have to understand that I
think
a physician needs to be very good at
being able to
recognize patterns and diagnose patterns
of disease.
But, an effective physician is able to
recognize patterns of people.
Because people are extraordinarily
predictable in their nature. I'm going
to give you an example. You're looking
at me. There's an eyebrow raise. Mhm.
I had, I'll tell you about one one
patient in particular, and every year he
put on this massive event. This massive
event in Vegas, made millions of
dollars, did well, and every year I
would wait for the phone call.
I'm feeling depressed.
I just did so well. I don't know what's
wrong with me. I'm off my diet. I don't
work out. I All the litany of things.
And
what he failed to recognize was as high
as he was going,
was as low as he was going to fall.
And I see that with all my Type A
individuals. I wouldn't say that there's
a particular
demographic of patient, whether they're
SEALs or CEOs or moms, but it is
definitely a mindset.
And the individuals that I see, they
want the best out of themselves.
And the other side of that, and I'm sure
you know many of these high performers,
they drive really hard.
But, they fail to recognize that as high
as they go,
after a book launch, and maybe you
experienced this with your own book,
you work so hard,
you
launch this book into the world, or
maybe your first massively successful
episode, which now maybe a little bit
less because they're all massively
successful,
but right after that, there's this dip.
And you don't go back to a baseline.
It's not like any other Tuesday. It's
a very big high and a very big low.
And one has to recognize that nothing
will take someone off any kind of health
and wellness journey faster than those
lows. And is that psychology or is that
physiology? I is that my mind and my
thoughts or is that my biology and
what's going on in my head? My
perspective is that it's physiology.
There is an internal
recognition or interpretation of the
stress,
but from my perspective, there is a
physiological response.
And from what I can tell and what I
believe and what I've seen is this
dopamine drive. It's, and of course,
this is a simplistic way of
talking about it, but there's this
drive, and they are so excited, they're
amped up, they've
spent a ton of time in preparation
getting ready
to do this thing, and they've
deployed so much importance on this one
thing that when that thing is over,
they're constantly grasping for the next
thing.
And we all talk about burnout as this
thing, and burnout happens that way.
And it's this drive of more.
And once you can recalibrate that drive
and understand that you have to have a
very neutral mindset going into things,
then people are able to mitigate and
manage their own physiology.
The mindset component is probably the
most important because I could give you
the perfect plan,
but if you are unable to to execute
that, then it doesn't matter.
There must be so many millions of people
that listen to my podcast that have
heard all of this advice
in terms of how to better themselves,
their cognition, their performance in
various aspects, and they still haven't
put any of it into motion for whatever
reason. And you must experience that,
too, in your practice where someone
comes to you, you tell them what to do,
but the how part is
sort of contingent on them having some
kind of motivation or discipline or
whatever it is. Um,
from my perspective, it's worthiness.
Interesting. It's when it comes down to
the fundamentals, it's does this person
feel worthy of having the health and
wellness Really? that they they Yes,
that they desire.
And if a person doesn't feel worthy of
doing it or worthy of having it, they
will sabotage themselves.
Once I explained this predictable human
nature to this patient of mine,
the game plan was he was going to be
neutral. He didn't go too high, he
didn't go too low, and there's very
specific strategies that we can talk
about the way in which one maintains
neutrality,
but at the end of the day he felt worthy
of feeling really good.
We covered intermittent reward, we
covered not celebrating every win,
um conscious
uh conscious turning it on and turning
it off, very controlled dynamic
expression of what the goal was.
Turning it on, turning it off, right? I
see this My husband is a former Navy
SEAL. I see this in this group of
individuals all the time. They're able
to have controlled intensity.
But the other individuals that never
seem to get better, so the individuals
listening to this,
the one thing that they would have to
really settle in on is do they feel
worthy?
And if someone does not address at the
core that they feel worthy
of executing the information that you
and so many others are providing, they
will never make the change.
Discipline, motivation, discipline is
easy. It's not difficult.
There are constructs in our mind that
may tell us it's easier to
oversleep or not go to the gym, but at
the end of the day discipline can be
practiced. It's not hard. Motivation is
another thing, but who waits on
motivation to execute? Nobody.
I mean, you shouldn't because that is a
perishable feeling,
but understanding that this worthiness
has to be addressed before people are
going to make any kind of change
becomes critical.
And typically it comes back to
what they tell themselves on a daily
basis, how they interpret their
environment.
Maybe they experience everything as
stressful
and don't feel worthy of taking action
to get out of that distraction of
stress.
So if I came to you and I exhibited
worthy worthlessness, I didn't think I
was worth much in my corner and you
could start to pick up on it. Maybe I
was
I don't know, I was carrying myself in a
certain way, my body language, the way I
was talking about myself subtly. I was
putting myself down. Um
and maybe you maybe there's other things
going on and you go, "Do you know what?
This guy doesn't think he's worthy."
Where would you start with me? Well,
first of all, I would let you come to
that conclusion. Okay. The first thing
that I would do is I would say, "Steven,
how are you sleeping?
Are you really sleeping well?"
And I would guess maybe you're not.
Maybe you're staying up late, your mind
is always going, you're really thinking
about things.
I would ask you how you're sleeping, how
are you eating, how's your digestion,
what are you being exposed to?
And then I would give you a handful of
tasks.
I would tell you you got to get your
blood work done. You have to do a sleep
study.
You know, we have to address what's
going on gastrointestinally.
Are you reacting to certain foods?
And
maybe you'll get that done or maybe you
won't.
But if you came to me and said, "I am
not feeling the best version of myself."
I would say, "Are you ready to figure
out what this is?" And then I give you
lip service and I say, "Yes, I am,
doctor." Yeah, and then we would have to
have a real conversation.
Because there's this interesting kind of
segue.
CEOs, and again, a large portion of my
population are CEOs, is they will The
predictable course is they're too busy
to get it done.
It's not a worthiness
aspect, but it is they're too busy. But
again, health is the great equalizer.
There will come a point that is very
predictable
that they will call me.
Um again, many of your guests have
called me saying, "Hey, G, I'm not
feeling
well. My stomach is really bothering me.
I feel like it's sour, I'm not sleeping
well, you name it."
And I go, "Okay, well, did you knock out
these five tests that we had to get
done?" And they might say,
"No."
Six months,
they will come to a point where they
will have to get it done.
Once they get those testing done,
now we start seeing the worthiness
aspect.
Now we have evidence of what needs to
change.
And those individuals that execute on
those change typically will understand
the importance of
the long game, right? If you want to be
as successful as you can,
be a maverick and make a mark and do all
of your
potential, leave all of your potential
on the table.
The only way that you are going to be
able to do that is to liberate your
health.
You have to. You cannot push past how
you are feeling. This worthiness thing
is really interesting to me.
Um because I do I can relate when I
think about certain people in my life
that have been unable to make the change
despite having all the resources, the
time, but it's hard to know if they have
the time because sometimes people use
that as an excuse. Well, also, Steven,
if people don't have time for health and
wellness, how are they going to have
time for sickness?
Mhm. That's so much more time consuming.
Mhm.
But they just People don't assume that
they're going to get sick.
Getting sick is a surprise.
But is it? I mean, it is it appears to
be for most people. They just We all
kind of live in Think about how we live
and the decisions we make in the short
term, it's evident that we don't believe
we're going to either die or get sick.
Which is a huge failure of our culture.
Um you know, when I think about
longevity and I think about aging and I
think about the individuals that fall
and break their hip and end up in a
hospital bed because they haven't
trained or haven't taken care of this
this body which we only get one,
there is a predictable endpoint.
It is happening and we spend all this
time trying to
increase this concept of anti-aging. We
are aging. Aging is not a disease.
How we do it is largely up to us.
And if we can
condense this future version of
ourselves to now
and understand not just the
physical
attributes, but also the mental
attributes that will require us
to move forward, then
people would begin to take action.
Can you tell when you meet someone if
they're going to make the changes that
you describe and that you suggest very
quickly? Yes.
And what are the hallmarks of someone?
They're like archetypes. Okay. You know,
there is the CEO archetype which I'm
telling you they are going to put it off
for good 3 to 6 months
and eventually they will get it done.
And once they get it done, they will
stay on top of it. They will get it done
because they recognize that their
physicality is the common denominator
cuz they are in it to be the best
version of themselves. Mhm. And then
there are other people that have gone to
13 other physicians and
have lost hope in the system. Mhm. And
those individuals or maybe they had a
physician that said something to them
and it really scarred them.
Those individuals will be very resistant
to execution, but once you earn their
trust, they'll get the job done.
Mhm.
And then there are individuals that
really struggle with worthiness.
That part of them wants to evolve, maybe
they had an old trauma,
maybe they had a physical trauma or
something
that really
really shook them.
And the trauma can be like a little T
trauma or a big T trauma. Yeah. It could
be a small thing that dad left, they
Yeah. you know.
Or it could be something bigger,
more horrific. Absolutely. And one of
the things that we see is
there is this interpretation of stress.
And people think stress is all fight or
flight. And we should try to de-stress
and take a hot bubble bath, but we
actually evolved to
manage and mitigate stress as humans.
We're much stronger than
we recognize and there are additional
stress responses that we don't talk
about. And we know from work out of
Stanford and
uh other individuals' labs that what you
believe about an experience is how your
physiology will show up about that
experience. So for example, there was a
hotel caretaker study. So you could call
it
a maid study where they looked at two
groups of housekeepers.
One group they said, "What you're doing
is amazing.
You are definitely getting physical
activity. Here's all the positives." And
the other one the other group they just
went about their day and you know, maybe
they were told that they should do
physical activity or not, but at the end
of the the housekeeper study, those
individuals that were told that what
they were doing
was in part like physical activity
showed low and that they didn't need to
do any more of what they were doing was
amazing.
Those individuals had lower blood
pressure, they had better glucose
regulation, better
insulin, they had lost a little bit of
weight, and it was all their
interpretation of the environment they
were in.
We tell people that the world is so
stressful
and that everything your internal
response is fight or flight.
But we have one word to describe
a million different things and we call
that stress. I'll give you an example.
A pet dies
or you have um a white sofa and your
kids just spilled coffee all over it.
Or you break up with a loved one or
there's a death of a spouse. We have one
word
and we call that stress.
That's it. We have one word to define
a million different things.
We live in an environment where people
talk about I'm so stressed and this is
stressful, but
that
we don't have any other word in the
English language
to globally define something.
Maybe that word could be love, but
not really, not in the way that we talk
about stress. So,
people think about stress as fight or
flight. That severely limits both their
physiology and their capacity.
The other two stress responses, which
are much more enhancing, is tend and
befriend, which releases oxytocin, which
makes people more capable. It makes them
more connected. This is the they're
stressed, yet they go to help other
people immediately. That's also a stress
response.
Or the courage response. The courage
response, we see that with a lot of
military operators.
A moment of stress, they're immediately
taking action. I'll give you an example.
If both myself and my husband were
getting read ready to jump out of a
plane, I would be terrified, and he
would be excited to do it. He would be
eliciting courage.
We're both in the same experience, but
he is having one of courage, and I am
having one of fight or flight.
When we both jump out of the airplane,
who do you think is going to be more
capable to get up and do the next thing?
Your husband. That's right.
I would still be
in this fear response, probably take me
at least a couple hours to recalibrate,
if not
a day or a week.
Whereas he has a response, which is
courageous,
and can be cultivated.
His capacity to then not only experience
new things, but continue on
will mitigate much of the physiological
damage that would happen from these
other fight or flight responses.
And what I would say to that is fear is
a normal response,
but having courage is a choice. You must
have You must have met people in your
practice that walk in, and they've got
some kind of trauma, which has led to
their state of sort of unworthiness. How
does one do anything about that when you
can't go back and write the wrongs of
their past, and
you know, I I I don't know if how much
you want to
dig into their psychology and become
their their therapist to try and unpack
some of that stuff, but if these things
are so deeply hardwired into them in
some way, you know, some early childhood
trauma that's stopping them feeling
worthy, which is stopping them having
{quote} and {unquote} motivation to
change.
Do you just give up on the person?
Never. What could you do? And can you
give me a specific example when that's
happened? Well, the first thing that I
would tell you is
I would turn to a coach.
I have an extraordinary coach, and his
name is Jim Kwik.
He is
He's worked with myself, helped make
that book possible, as as well as other
individuals whom you know.
And
that requires someone who is really
willing to go in and dissect that.
I have to know where physiology ends and
psychology begins.
I will also say I trained in psychiatry
for 2 years.
And the mind was, of course, the most
fascinating part for me at first. That's
actually what brought me into my work
with the military that I do today.
I will tell you that if I were to think
of
a very particular
patient, I will.
She had a lot of trouble sleeping.
And this woman, we later found out we
did everything. We did a sleep test.
Didn't have sleep apnea.
Was extremely unsettled.
Really um
had hormonal problems, put her on
hormone replacement, still really
struggled with sleep.
Did all of the things that one would
need to do, like a dark room.
I know you had Andy Galpin on, he does
talks about sleep and has absolute rest,
and you know, we looked at her
environment, did everything.
At the end of the day, it turns out that
the reason she wasn't sleeping is cuz
she had been assaulted.
And she had forgotten.
But every time she would go to bed, her
heart rate would spike. Um and it was
something that
that wasn't my domain,
but I knew that she had to really
deconstruct that if she was ever going
to move forward.
Part of it is figuring out where
there are weaknesses and vulnerabilities
within a person.
Because we think about the way that
health care is set up, right, is that
it's you see a doctor for 15 minutes,
maybe it's a half an hour intake, and
then you're on to the next.
But a real therapeutic relationship is
exactly that. It is a real relationship.
It is not transactional.
If you are a physician, you know, being
a physician, it used to be a very
honorable thing, and they were on the
council for people. It was
you know, they were your right hand.
And we have really changed from that.
You know, I'm talking about maybe in the
1800s.
It was a very honorable, privileged
position, and I still believe it is
that.
And so part of moving people to from
where they are to a level of wholeness
requires being a teammate.
Do you try and motivate people? All the
time.
that's part of your your remit
as a physician to motivate them? Part of
my
job as a physician is seeing what they
are capable of. Mhm.
Is seeing what their true potential is.
And to push them? Yeah.
Do Do some Do sometimes people need a
bit more pain
before they
Yes. And then I mean, this speaks to
what what's going on with like
motivation and discipline, because if
you need a little bit more fear and a
little bit more pain, then it kind of
illuminates what this what's actually
going on with people's motivation. You
can almost put it into a formula where
like the strength of their their why
is at one side of the that equation, and
then there's some some other factors in
the equation, but it seems to start with
the strength of their why, and pain,
more fear, a bad result seems to amplify
their why to the point they go, "Okay,
[ __ ] it, I'm going to do something about
this now."
Yes.
And I think that there is a potential to
not wait till that happens, because it's
very predictable.
You know, and if someone is listening to
this or thinking about it, you don't
need to have to wait to get to that
point, because that point of breakdown's
going to come.
And you might as well get ahead of it.
You can only push so far.
Your original question is, do I think
that part of my job is to motivate
people? Yes.
Do I think it is also to see their
weaknesses and vulnerabilities?
Being a physician and and taking care of
some of the most extraordinary people
in the world, you get to see behind the
scenes.
And the people that are doing
extraordinary things,
their characteristics are actually not
that different.
They are often times extremely motivated
by service.
They are It's not a self-service, it's
an other service.
And when you can tap into say, "Hey,
listen, in order for you to really be
able to expand your reach,
grow this legacy, change the world,
then we have to fall back on
the things that you are completely
ignoring." And again, uh vulnerability
is hard for people,
but exposing that and letting them come
to those conclusions,
then
you see a full evolution of a person.
You How many I mean, how many patients
do you think you've seen over the last
Thousands. Why do you do what you do?
I
find the greatest joy,
aside from my kids and my husband and my
family,
being able to be of service. Why? Well,
I would say that I'm always I've always
been wired to be this way.
I have always been wired to take care of
people.
And I would say right now, when I think
about
my patients like Danica, or um some of
the other entrepreneurs that you've had
on,
I believe that no one is going to be
able to get the job done better than me,
and is going to care more.
And
it feels really good to be able to be
there for people.
Are you a happy person? Yes. For the
most part, I would say I have a very
positive disposition.
I do. What are the seasons of
unhappiness in your life?
I think during training was very hard
for me, during my fellowship.
Saw a lot of death.
That was really hard.
Work a lot of hours, see a lot of death.
That was hard.
You still remember that? Oh, yeah.
Changed you? Yeah.
That's why I got into social media.
I had just finished my fellowship, um
2015,
and I hadn't been on social media or
anything.
And I had just been, you know, you go
through
and you see patient after patient,
and
you know, none of them are getting out
of the hospital. They're all going to
die there.
Can you imagine?
So, you're seeing 30
30 patients a day.
This one is on pain meds, you know this
one is going to die. This one is
18, and she's going to die, and she's
planning her wedding, but she has um
She's planning her wedding? She was
never going to be able to She
had um cystic fibrosis.
There was nothing that they could do for
her.
And she was never going to have a chance
to get married or do anything. And she
was planning her wedding? She wanted to
pretend like she was going to be able to
get married.
Picked her dress to
have an experience she was never going
to have.
And um
you know, during that time
I
you know, as I was coming out of
fellowship in 2015
I was seeing all this BS on social
media.
These people talking about you know,
this cleanse and this fake diet and this
like all of this stuff and the
information was so bad.
That
I felt responsible. That if I had
the privilege to have, you know, had a
17-year education
and I've seen all of this stuff and then
to not say anything that I knew was
going to make a difference or be
impactful for people's health and
wellness.
The end comes.
The decisions you make become critical.
But where it really becomes critical is
in the beginning.
The children and then at the end.
And if you start hearing all of this
narrative of how we you know
um
should reduce our dietary protein and do
all these other things and destroy our
skeletal muscle based on this input that
we're getting.
The information was so wrong
that I felt a responsibility to say
something and if
I didn't, I would be contributing to the
same problem.
But it was very hard.
It was very hard.
Does that come at a cost? The the the
caring.
Yes. Yes. Yes, it does. Nobody has ever
asked me that.
Yes, it does.
It um and this might not be the best
trait, but I am
willing to
be there at midnight, at 1:00 if someone
needs something.
I got it.
And yes, does that come
at a cost to myself? It does. And my
family? It does.
I am very careful about protecting the
time. But um
yeah, it's
Is there an emotional cost to this as
well? Because if I if I was every day I
was waking up and I was
being involved with other people's
problems in such a way, other people's
challenges, their sickness, their
illness, their
their death.
I
I don't know if I'd need some strategies
to to cope with that. Like
getting invested in somebody and then
seeing a bad outcome. And feel that sort
of feeling of like, what could I have
done? Or
you know.
Well, luckily um
my patients are no longer, knock on
wood, life or death. We are dealing with
things like um
hey, you live in a toxic mold
environment or you have Lyme. Um we can
move past this or hey, you have COVID
and you're in Washington, let me get
some Paxlovid sent to you. Or
um maybe this person is going through a
bad breakup or
their thyroid is off.
It's light in that way. I mean,
sometimes I have to send people to the
hospital.
But it's no longer caring for end of
life, but
now
it is positive and
it is challenging.
But
again, I've been a physician for 20
years.
You build up capacity.
I was thinking the other day about some
of the like mind cuz
a good idea that infiltrates your mind
can change your life. Yeah. Because it's
kind of like corrective. It like it's
almost like it goes in there like a
vaccine and it attacks a a mind virus
that you had. Something that was holding
you back, some kind of limiting belief
about the nature of life.
In your work, what are those kind of
mind viruses, those myths that people
carry with them that ultimately inhibit
their chance of becoming this optimal
performer that you want them to be?
There's a handful of things and also we
have to recognize that we're talking
about two things, physiology and
psychology.
From a
physiology, from a physical perspective,
there is a one of the things that is
extremely detrimental is this
comparison.
Individuals that compare themselves
physically to other people will stay
hooked in.
That typically is a comparison of youth.
As individuals mature in their late 30s,
40s, I do see that dissipate. But if
that doesn't dissipate, they will
continue to hone in on this physical
readiness and that allows for certainty.
So, think about this.
We all see
amazing athletes or people that are in
incredible are incredible shape. And
your ultimate question is, what are the
things that limit, whether it's a mind
virus or something limiting to allow
somebody to become
the best version of themselves, an
uninhibited version of themselves or
unencumbered from a physical standpoint.
When an individual is solely focused on
the physicality Mhm.
and that can be from a looks perspective
that can be from, you know, my husband
always tells me stories about those guys
that go into SEAL training.
The first guys to wash out, this is what
he tells me, were always the great
athletes.
Because they had trained physically.
They were capable of dealing with
certainty.
You throw a ball, you know how to do
that.
They hadn't prepared themselves for
mental uncertainty or fortitude. And
this circles back to this. So, the
individuals that are fully focused on
this external comparison, it's about
looking good, it's about being fit, it's
about having more plastic surgery, less
wrinkles, whatever it is.
Those individuals are chasing a game
that they will never catch.
The perspective is wrong.
We all get older.
We all will at some point not be as
physically capable
as we are now. You're in your How old
are you? 31. Oof. Getting up there. Mhm.
You are 31.
getting up there? You mean I'm getting
old.
No, I cannot talk. Um
but there is this physical capacity that
if you were to just say, Gabriel
let's just focus on the physical.
Then we know by the time you are 50 and
listen, 50 is not a great number because
we I a ton of amazing fit 50-year-olds.
But when you are 80, if all you did was
look at that physically, by the time you
were
more mature
you
would become, and I don't want to say
more depressed, but this if your world
is purely external
there is an inevitable decline in that.
And you know what I'm talking about,
right?
Time is against you. It's going to
happen.
You know, your skin is going to sag,
whatever it is. Hopefully it doesn't,
but
those individuals that are fully
externally focused those individuals
really struggle with aging.
And you will not focus on the things
that matter.
And that is a virus that will happen.
You will always be comparing cuz it will
bleed over to everything.
How you manage your psychology will be
how you manage your physiology.
So, what should I be aiming at?
What should in if I'm not going to be
aiming at the physical attributes and
the comparison what what kind of measure
should I apply to myself to understand
if I'm doing a good job?
You should focus on physical readiness.
But it shouldn't be about how you look.
Okay. It should be about how you
perform.
When you think about gaining physical
readiness it should be about the
acquisition of skill the acquisition of
strength.
I talk a lot about muscle. I believe
skeletal muscle is the organ of
longevity.
You should be focused on becoming
physically strong.
But the physical performance
outcome, how you look, is not the end
point. The idea that you are training
for life able to, whether it is to run
or to squat or to bench press or to get
stronger in a meaningful tactical way
you should continue to move that needle.
A lot of people though, they we were
talking before we started recording
about how people are driven by like
short-term incentives.
And it's quite insane for someone to
focus on a long-term incentive in the
face of like a short-term incentive. So,
if I if my short-term incentive is for
someone in the office to think I'm hot
or, you know, to find a partner, I'm
going to be so focused on getting that
blow dry.
I'm going to want that like facial.
And I'm going to if I've got, you know,
an hour of free in a day, I'm going to
aim at the facial, the blow dry. How can
you convince me that that's a bad idea?
Versus aiming it at, I don't know,
building muscle or becoming physically
strong.
Time is finite.
And we are given time.
How we spend our time will determine our
outcomes. It will determine where we're
going. How globally strong we become
because strength is clearly not
physical. There is a level of global
strength, which means
becoming masterful at something. For
example, you're masterful at business,
at interviewing, at learning and
thinking about people.
If you were distracted and you could
totally choose a life of distraction
you could be distracted by the external
shiny objects.
Perfectly okay.
But that outcome, if that becomes
regretful
then that becomes devastating.
You know, um taking care of people at
the end of life
you hear a lot of regrets.
And it wasn't that they wish they'd had
another blow dry. And I know what you're
saying is that how do we think about
later life if we
can't identify in the short term or take
in the short term what makes us happy,
right? We are thinking about I want this
cake, I want this thing, I want to buy
this car. Shout out to my husband, no we
are not getting that Defender.
But the short term is very limited.
And we live in very fast-paced society
that will tell us to embrace that.
And to fight for that thing.
But it only takes a moment of spending
time with the elderly or the aging or
people that are wiser than us
to look back and say these are the
moments that you can fully develop
yourself. And again, from a physical
standpoint, should you focus on physical
readiness? Absolutely. You're 31, do you
think it's going to be easier at 41?
I hope so.
We got to get you on a good program. Um
I'll call Lane later, but
you have to do these things.
And you have to bring back into
perspective what is important and what
is valuable. I'm thinking about a
particular friend of mine who I was
describing there with the blow dry thing
and and the like spray tan and the blow
dry. They're they're you know,
approaching 40, they're looking for a
partner.
They
are spending any free time they have on
the on the spray tan and the blow dry.
Listen, I'm not not judging. I'm just
saying that as a case study.
and there's many people like that. And
they're spending zero time on physical
strength, don't go to a gym, don't go
near it, don't do any exercise.
And I'm just wondering, you know, how
you make a case to that individual that
actually to achieve the goal that they
want to achieve, which might be to find
a partner, actually it's the inverse.
It's they should be doubling down on the
internal versus the sort of surface. The
first thing that this person is
obviously driven by the external. Mhm.
And you have to recognize that you
cannot have
a strong physical body if you are
mentally weak.
Because you will never feel good about
what you are doing. You will be
distracted. You will live a life of
distraction that will then rob you of
your future. Mhm.
And the case I would make to your friend
is
these immediate distractions and being a
good friend would be telling them this
or allowing them
to come to that understanding. When you
say you can't have a strong body unless
you have a strong mind, how are you
defining and how do you define a strong
body?
You should be able to be physically
capable in whatever it is that you want.
Should you be able to do a pull-up?
Probably. Should you be able to do at
least 10 push-ups? Yes.
Is that number different for everybody?
Yes.
If I asked you to please run a mile,
could you do it and do it well?
I think being and having physical
sovereignty and being able to be in
control of your body and to be strong
and not require someone to help you with
things. I mean, granted you probably
couldn't lift a car by yourself or a
bed, but
But this
But this becomes extremely important for
our aging population and for where we
are now.
What do I mean by this? We are becoming
increasingly weak as a society.
The majority of individuals are moving
towards obesity.
Children are becoming more and more
obese.
Are they strong? Are they as strong as
they could be from a physical
perspective? I would say no.
And again, you can choose
a marker of goals to hit.
Which I recommend that everyone does,
whether it's squat,
deadlift, you name it, run. But you have
to be able to have accountability for
your physicality. If you were going to
be giving me goals to hit,
right? And I don't necessarily mean like
10 reps, whatever, but just
the types of goals that I should be
aiming at to have a strong body,
what what are those types of goals? So,
you mentioned squatting there, you
mentioned, you know, maybe being able to
pull myself to run. Are these the kind
of goals that you would give to me? So,
say a 30 40-year-old, what kind of goals
would you be aiming at? And are the
goals different if I'm 50 and 60? They
are.
You should
at a minimum
And I'll give you an example. Um you
should at a minimum be training 3 days a
week with with weights, doing resistance
training. You've had many uh you just
had my friend Mike Israetel on. I mean,
that guy, he is jacked. He could
probably lift you with one hand and me
with a pinky and he would be
going all over the place.
You should be training
your muscles from a strength and or
hypertrophy standpoint 3 days a week.
Okay, so is that everyone? Yes. Everyone
regardless of age?
Yes. Yes. So That part is regardless of
age three to
Listen, could you get it done in 2 days
a week, which is the recommendation?
The current recommendation for activity
is 150 minutes of moderate to vigorous
activity and 2 days a week of resistance
training. Is that going to be enough to
keep you walking around? Yes. Is that
going to be enough to evolve your body
to
manage and mitigate aging? No, it is
not.
We have to call ourselves to a higher
standard. Three to four days a week.
Four, you've added a day.
Okay, well, I was going to say three. I
was going easy on you. Three days a
week. You should be doing And I only
train I do resistance training 3 days a
week. I might throw a fourth day in
there. For anyone that doesn't know what
resistance training is? Moving um
your body or a load against
um
uh resistance. So, it would be for
example, taking a weight and moving that
through space, whether it is a squat or
a bench press. These are all resistance
training, moving against a resistance of
some load. It could be body weight, it
could be a band. Three days a week,
everybody I mean, I'm I'm okay with 2
days a week,
but in an ideal world, it should be 3
days a week.
My recommendation is you train for
muscle hypertrophy. Which is? Muscle
growth.
10 to 20
sets per muscle group a week. And how
many reps?
So, I would say
um you could do a
upper body, lower body split. You could
do
What's that? Um a push pull, like a
bench press or a a back row. So,
back and um chest. You could do full
body training, which is which I think is
the best for people. Compound movements
like a squat or a deadlift. This is full
body.
You should be doing some kind of
movement, but
Stephen, if someone said, like my dad,
before I came on this podcast, he
FaceTimed, he lives in Ecuador, and he
was doing resistance bands with bicep
curls. Mhm. I'm okay with that.
If you want to do that and that's how
you're going to do your upper body or
your arms,
fine.
So, it could be chest, back,
you know, glutes, legs.
Why should I be doing 3 days a week?
What what am I going to get out of that?
Make make the case to me.
Number one, you are never going to
regret being stronger.
Period, end of story.
You need to be physically strong.
Skeletal muscle is the organ of
longevity. It is not just about good
looking good
in a bathing suit. It helps, it's so
great. Um your friend who is getting her
hair blown out and doing all these other
things,
put her in some training and listen,
she's probably going to be a killer.
Skeletal muscle is your primary site for
glucose metabolism, fatty acid
metabolism, it's your glucose sink.
If you decide that you want to eat
carbohydrates and you care about
metabolic health, you have to have
skeletal muscle.
You're not convinced yet, are you? I'm
I'm listening. Okay, well, you're you're
kind of like
maybe convinced that you think skeletal
muscle is important, but if I told you
that this is your body armor,
that if you are in the top 1/3
of strength
compared to if you are in the lower 1/3
of strength,
those that are in the lower 1/3 for
strength
have a 50% greater risk
of dying from nearly anything.
If you are in the lower 1/3 of strength,
you have
a roughly 50% chance
of dying from all cause mortality.
But I'm getting old, Dr. Lyon. I I'm I'm
58.
Yeah. Um when people get old, they put
on weight, they they lose muscle, we get
weaker, we get frailer. This is what
this is just the nature of life. Don't
fight life. The first thing that I would
say is congratulations making it to 58.
Well done, sir. And then I would say
that is totally not true. That is not
what we see in the literature.
Anyone at any time can get stronger and
put on muscle.
Anyone at any time can get stronger and
put on muscle. Do you know what it is,
yeah? Part of the reason why I think
people don't believe that is because we
look at our parents
and our parents looked at our parents
and our parent their parents looked at
their parents and our parents are like a
case study of what we what we should
expect. They set the expectation. And
when a lot of us look up at our our
parents, we see people that are maybe
have had a little bit of weight added,
um maybe our dads have a bit of a pot
belly because of all the beer they've
been drinking or whatever. Yeah. Maybe
they walk a little bit slower, they
can't run, they're out of breath. So, we
kind of just assume that that is normal
and that's what we should expect of
ourselves.
And I think I I did that. I looked at my
dad who um he's on a bit of a health
journey at the moment, but before he was
on that health journey, I did kind of I
think at some point in my mind I
conceded maybe that's just what like
genetics do. They just give you a pot
belly, they slow you down, you lose your
muscle, you get weak. Yeah.
That funny thing about humans is when we
hear and see things over and over again,
we believe them to be true whether they
are or they're not.
Humans are funny creatures in that they
experience repetition as truth.
What do I mean by that? I say, "Steven,
this is stressful. This is stressful.
Our fight or flight is the only way."
And then you go, "You know what,
Gabrielle? Fight or flight is the only
way."
That's all I've ever heard.
We see our parents age
and we believe that that's just the way
that it is.
But I can show you
many
individuals that are aging well and
strong. Both of my parents are
incredibly fit.
Is that genetic? Maybe I picked my
parents well.
But what I will say is that the
traditional
framework of aging
is in part the way that it is because we
have divorced the idea of skeletal
muscle
from health.
The bros got it right.
You need to be jacked, you need to be
tan, and
if you're not jacked and tan or if you
are,
resistance training is only for
the bros.
Nothing could be further from the truth.
And because of that thought process, we
have divorced skeletal muscle health
from overall health and wellness and
longevity.
If I as a trained geriatrician were to
say,
and by the way, I did 7 years of
nutritional science training as well.
If I were to tell you what is the one
most important thing to take you through
life,
do you know what I would say? Probably
muscle. That's right.
Hands down, across the board,
the weaker you are, the less muscle mass
you have, the greater chances you will
die. So, in terms of cardio, is do you
think muscle mass is more important than
cardiovascular exercise as you age?
You're putting me in the hot seat, and I
would say both we know are important.
But
again, both are very important.
But there is no replacement for
resistance training
and muscle mass. There is none.
You will not get the same stimulus by
doing cardiovascular activity, and you
need You mentioned your parents or your
dad. You see and we see collectively
our aging population shrink,
right? They become thinner and and
scrawnier and
more sarcopenic. We see this happen.
There is a transition of fiber types.
There's different fiber types, and they
transition from type two fiber types to
type one. What is that? Type two are the
big, bulky fibers
that you train for hypertrophy, strength
and hypertrophy for.
There is a transition that happens if
you are not constantly fertilizing these
muscles through strength and hypertrophy
training, through resistance exercise.
If an individual is solely focused on
cardiovascular activity, this will not
maintain in a meaningful way
these type two or bigger, bulky muscle
fibers.
When you lose skeletal muscle mass,
you also see a change in metabolic
health.
Muscle is the primary site for glucose
disposal.
It is
primary site for fatty acid oxidation.
When you
lose skeletal muscle,
you see an increase in
blood sugar, insulin, type two diabetes.
Skeletal muscle is what allows us to
buffer
the foods that we eat. So, if I'm eating
lots of sugar and carbs, for example,
Yeah. and I've got lots of muscle,
then
the sh- the sugar and the carbs going to
be basically stored in my muscle. But if
I don't have any muscle, then where is
it going to go? Exactly.
Liver, fat. You are going to become
increasingly unhealthy unless you are
training.
So, if I if I have more muscle, does
that mean I can eat more carbs and there
be less of a consequence? Likely, yes.
Especially if you are training and you
have healthy skeletal muscle.
Um skeletal muscle can be marbled. A-
You can get an increase in myosteatosis,
which is fat infiltration in skeletal
muscle.
In order for skeletal muscle There is no
such thing as a healthy sedentary
person.
You will look in the literature and you
will see
people say, "Oh, healthy sedentary."
There is no such thing as a healthy
sedentary person.
What do I mean by that?
There was some wonderful work out of
Yale. They looked at 18-year-old
college students that were considered
lean and healthy,
put them in
a-
a time frame of inactivity, and they
become they became insulin resistant.
They had skeletal muscle insulin
resistance
even though there were no outward signs
of obesity or fat.
If you are not active,
you will not be turning over your
glycogen stores, which is the stored
form of carbohydrates.
You will begin to build up byproducts.
Your skeletal muscle will be
increasingly more unhealthy over time.
You cannot get out of doing resistance
type exercises. And to be clear,
you do not have to be doing a one rep
max.
You could simply start by body weight
resistance training.
It could be yoga, it could be bands. But
at some point, you will have to
stimulate that tissue in a meaningful
way
to age well. How many people are meeting
the activity guidelines at the moment,
and how many people aren't?
Roughly
6 to 8% are meeting the resistance
training guidelines.
6 to 8%?
Yes, sir.
Just if you were to look at resistance
training guidelines. Now,
50% of Americans don't even work out.
Over 70, roughly 75%
do not meet both recommendations.
The majority of individuals are
sedentary individuals.
It's interesting cuz people will then
say, "Well, you know, these stats are
all bad, but our life expectancy seems
to have gone up,
you know, year over year for Well, I
mean, I think it's had a little bit of a
blip recently because of COVID, but it's
typically going up into the right, our
life expectancy. So, we must be doing
something, right?" Is it about life
expectancy or is it about quality?
Could we keep someone alive on bed rest?
Probably.
Would one say that
that would be a good quality of life?
You cannot have a high-quality life
without high-quality muscle.
More specifically, people care about
autonomy.
Can you imagine if you couldn't
physically get your groceries?
You are young.
We are young. We take for granted the
physical capacity
that one has.
That is a gift. It is a skill that must
be
continuously
pushed,
or the trajectory of aging is exactly
what we see.
People get to a point where they can no
longer
lift their suitcase
on an airplane overhead. Do you see
that? Yeah. People struggle to get their
bag on the belt to go through security.
Is that normal? That is not normal.
How do we know this? Are there other
sort of societies where they just age
better than us? Um and they're, you
know, they've got 60-year-olds that are
being able to lift their bags above
their head.
I mean, I can tell you from
my father's community in Ecuador.
My dad is 74.
If something is a 3-hour
walk or less, he'll walk it.
I definitely don't like to go visit him,
as you can imagine. It's a lot of
walking.
They are extremely physically active.
They seem to age well, and I think that
you will find pockets of individuals
who
do things that are very physically
active throughout their life span,
which will allow them to maintain a
muscle span, which is the time in which
they have quality skeletal muscle.
I will also say we control our
environment.
Everything can be easy for us if we
choose.
You can take the escalator, you can take
the elevator, you can get in the car,
you can do all of these things.
Inoculating yourself against muscle
aging
takes effort, but it has to be done.
Each time someone has a choice to either
do it
physically themselves or to take the
easy way, each time an individual
continues to take the easy way,
the
predictable decline
will
conti- It's like putting another coin in
the bank, but maybe that bank is being
spent on something worthless. That's
exactly what happens.
What are the misconceptions people have
about um weight loss? You've touched on
it a little bit, but i- if I've come to
you and I say, "Listen, Dr. Lyon, I'm
going to be honest with you. I just want
to lose some of this belly fat.
I just want to be um lean, and I want to
be beautiful.
Um should I get liposuction?
Um what diet should I go on? What would
you say to me?
First thing that we have to figure out
is your muscle mass. I mean, this is a
little complicated because I would, of
course, ask them how we got to where we
were.
Right.
How do we get here?
Are you
emotionally eating? Are you,
I don't know, not sleeping? Or what are
the Are you drinking too much? What are
you doing? What are we up against? What
are the actual tactical behaviors that
we're up against? Mhm. And then, I would
say,
let's go.
We're going to build some muscle.
We have to work on some body
recomposition.
And really, the two ways that we're
going to start are the two
basic, and that is diet and exercise.
So, no lipo-suction? I mean, Stephen, if
you wanted to, I do know a great plastic
surgeon. Okay. But, no, unnecessary.
And again, this goes back to this
hyper-fixation on body fat.
When the conversation should not be
about
obesity drugs or body fat,
the conversation needs to swing back
to not about making people less obese,
but to making them have more healthy
skeletal muscle.
What's the link there? So, how is having
more skeletal muscle going to My gluco-
the
glucose is going to be stored in it, so
that means less glucose is going to be
stored in my belly fat.
My metabolism's going to be better, you
said as well, so
your ability to store glucose Yeah. will
be from,
you know, obviously stored in your
liver, but skeletal muscle is the
primary site for glucose disposal.
Am I going to be less hungry?
Now, that is a great question, and there
is observational data, and I say this
very hesitantly,
because it hasn't been published yet,
but
I believe that we are going to begin to
see that skeletal muscle
has a role in appetite regulation
because of receptors on skeletal muscle.
You will not find anything out there
yet,
but I do believe that there is
observational data from some of my
colleagues that are doing research,
that we will see that there is some
appetite connection
with skeletal muscle. Well, I burn more
calories when I'm working out if I have
more muscles.
You will.
What about Ozempic?
Should I Should I consider a little bit
of Ozempic on top? It depends on how
long you've been struggling.
Okay. I am
I do recognize that these are
very complex issues.
Whether it's Ozempic or Mounjaro,
GLP-1s, or GIP,
these drugs,
these
drugs are here to stay.
I do think they play a role. I know you
had Dr. Tina [ __ ] I am fully in
alignment with much of what she said.
There is an absolute role for this.
I will also say
that why is it
that
within that conversation of body
composition,
why is it that it is so much more
socially acceptable
to give someone a medication
to decrease obesity,
yet the idea of giving someone
a medication
or an anabolic like testosterone or a
testosterone derivative
would be shocking
to people.
I can administer a drug to make an
individual less obese,
but there is an incredible amount of
stigma
if I wanted to administer a drug to
allow someone to have stronger, bigger
muscles. What kind of drugs would you
administer to give them stronger, bigger
muscles? Testosterone would be my first
one.
How much testosterone though?
It depends.
Michael, he was uh on the podcast
previously, he told me that taking
testosterone and steroids made him angry
and gave him really vicious thoughts,
dark thoughts. But, Michael
is a professional bodybuilder.
And we know that there is health and
wellness,
and that those that operate at the
pinnacle of their sport,
that does not mean that those
individuals are
training in a healthy amount, right?
There is a cost of doing business
at the peak of anyone's career in
anything.
And from a physical standpoint,
certainly.
That utilization
would be different than someone coming
to say, "Hey, I need to work on my body
composition."
The big point here is the dichotomy in
conversation between the two.
It's fully skewed
in the way that it is much more
acceptable
to give a medication
to address obesity, and much less
acceptable to give a medication to
address skeletal muscle mass.
And I personally believe that that
conversation needs to shift. A lot of
people say that Ozempic causes muscle
loss as well. It doesn't. Really?
I have not seen a direct mechanism of
action
that Ozempic
affects skeletal muscle in a negative
way. In fact, I have seen the contrary.
There is evidence to suggest that
Ozempic and individuals like these drugs
in this class can actually support
skeletal muscle health.
The reason individuals are losing
muscle mass
on these drugs
are because they are not training
and managing their dietary protein.
There's only two ways to stimulate
skeletal muscle,
and that is through resistance training
and dietary protein.
You cannot out-medicate
poor behavior.
Oh, but but because they're on a
appetite suppressant like Ozempic, that
means that probably just not getting
their protein. We utilize these drugs in
my medical practice all the time.
We track body composition
all the time. It is routine.
We track muscle mass.
We do not see a decrease in skeletal
muscle mass when individuals are dosing
protein appropriately and training.
Does Ozempic and these that category of
drugs will people of a certain
psychological mindset benefit?
That's a wonderful question, and here is
what I would say as
a physician who is in practice.
Removing
physical obstacles are critical.
And individuals can spend time obsessing
about their body,
um
just really it can
infiltrate their thoughts.
It takes away from their capacity to
show up in life,
to be present, because they're worried
about their weight.
And can you imagine if
someone was struggling with that for a
decade or two or three?
Now, we have a new class of drugs
that will take away in part a desire to
binge eat, or take away in part a desire
to even potentially drink alcohol.
What it allows for is physical freedom.
Do I think that that comes with a cost
of not doing the hard thing and
and doing those
kinds of behaviors?
It does. It does make things easier.
However,
there is utility in that. Yeah, cuz if
someone suggested it to me, I'd say, the
first thing I'd say is, "Dr. Lion,
what's the cost?"
Cuz nothing's free in life, so and if I
don't know what the cost is, that's even
more scary.
I'd rather be able to balance the
trade-off, but not many people are
giving me many costs for Ozempic at the
moment.
Well, number one, you don't need it.
Yeah. You would not be someone who needs
Ozempic or Mounjaro or Zepbound. You You
just wouldn't be someone who needs that.
Um but, I do actually believe that this,
in combination with hormone replacement
therapy, is going to be the way of the
future for longevity. What's the cost?
I cannot tell you
what the cost is, and here's why.
Because people will say it slows down
gastric emptying.
Um yes, that's exactly what it is
supposed to do. Will that have a
meaningful outcome?
Not necessarily. These drugs are not new
drugs.
This class of drug is not a new drug. It
has been around for the last 20 years. I
know at least the last 10.
There must be a cost though.
The cost is when you go off of this,
Yeah. you likely have, and again, this
is just my perspective, is once you
titrate off, then normal hunger cues
should return.
And if you do not have appropriate
strategies in place,
an individual will then begin to
struggle,
potentially regain the weight. Have you
seen this? I haven't.
We take people off these medications all
the time.
And they don't rebound.
They do not rebound. They do not
rebound.
But again, we do very intensive
lifestyle interventions. We also
figure out why people got
into the place or the hole where they
are starting. Why?
Right? You say there's no free lunch,
and maybe the no free lunch is you have
to address old trauma.
Maybe one will really have to explore
the way in which they cope, right?
Cannot cope with emotional eat like they
You cannot do these things.
If you want to maintain
your body composition as you age,
you have to be accountable for these
things.
Do diets work?
Do you ever put someone on a diet?
If they're over consuming calories,
yeah. And what does that look like? For
us, I mean, we've been doing this for a
very long time.
We The first thing that we decide is
dietary protein.
Which is unfortunately seems to be the
most controversial macronutrient. Which
by the way, you looked at me crazy and
you're absolutely right. Why would any
macronutrient be controversial, but
dietary protein, again, it wasn't like
this until the influx of social media.
And what do I mean by that? Dietary
protein, it just seems as if there's
always a reason why people are trying to
remove it from the diet. Which seems
somewhat ridiculous and
counterintuitive.
The first thing that we do is we
recognize that dietary protein is what
the foundation of any solid nutrition
plan should be built on.
And that is 0.7 to 1 g per pound ideal
body weight.
If you eat high nutrient-dense foods
like animal products, you could probably
go to the lower end at 0.7. If you are
someone who does not eat any kind of
animal product, you're probably going to
be closer to 1 g per pound ideal body
weight of
um whatever that source of protein is.
But protein is what is going to maintain
hunger.
You know, uh dietary protein does cause
an increase in GLP. GLP-1 in the body.
And people will talk about that,
although it's only meal to meal. Which
is so you know, you have these GLP-1
agonists which improve satiation. So
like a a Zempic is a GLP-1 agonist which
makes you less hungry.
Yes. Dietary protein, in part, works on
that same kind of mechanism. Also
releases GLP.
Which makes me less hungry?
Yes. Okay. It will improve your improve
your satiation. Okay.
Dietary protein, we know, can help
regulate hunger.
Can also
maintain blood sugar, right? If you have
carbohydrates in in check. Not a very
efficient way, but your body can
generate glucose from dietary protein. A
lot of people associate protein with
like bodybuilders and stuff like that.
I know, it's such a mistake. It's a
mistake.
Because as individuals age, they need
double the the minimum recommendation to
prevent a deficiency.
The current recommendation is 0.8 g per
kilogram or 0.37 g per pound.
If someone was 115 lb, their dietary
protein recommendation would be 45 g.
That would be the minimum to prevent a
deficiency.
As individuals age, they require more
dietary protein
because skeletal muscle becomes what we
call anabolically resistant.
It means it becomes less efficient at
utilizing dietary protein. If you were
to eat the way you did maybe in your
teens and 20s.
Body at that time is extremely anabolic.
What's that mean? You look like you're
pretty fit. Have you always been pretty
fit? No.
Pretty fit in terms of what though? I've
not always had as as much muscle mass as
I have now, but I've always been
um fit as in playing sports and stuff my
whole life. And has it been easy to put
on muscle?
Generally, I'd say yes. When I was
younger, it was a it felt a bit more
difficult, but I just think I had had
things wrong. I don't think I was
consuming enough calories.
Mhm. But as of as I got to sort of 25,
26, 27, it became a little bit more
straightforward. Which is amazing. Your
body is highly anabolic. You are now
consuming calories,
protein, you're able to put on skeletal
muscle. Mhm. That tissue is very
anabolic. It's sensitive to the foods
that you're eating, to the stimulus
you're providing. As you age, that
tissue becomes more resistant.
I've got friends that tell me they can't
put on muscle easily.
How old are they? One of them's 27 and
the other one I think is about 29. Okay.
And they're men.
And they've told me that
no matter what they do, they just can't
put muscle on.
Well,
first things that I would do is ask them
what they're doing. Are they consuming
enough calories? Do they have enough
protein? Where do you think they're
going wrong when I said that?
The fir- You want me to be honest? The
first thing that I thought was
I am seeing a huge increase in low
testosterone levels in younger
individuals. Interesting.
And um I know it's just me and you and
not the millions of people that
watch your show, but um
the medical answer would be they should
look at their diet and training and
sleep. But what I am seeing clinically
is that young young men have
increasingly low levels of testosterone.
And how does that link to them not being
able to put on muscle? They are
um less anabolic than they should be.
What does anabolic mean? Building. They
are less capable of building. Okay. If
if I This is a
problematic question. Um
is there any way to tell if someone has
low testosterone just by kind of looking
at them?
Some of my colleagues might disagree
with this.
I would say you could potentially guess,
but do they have less um
hair on their legs? Do they have less
muscle mass? Do they have um
what would look like potentially more
estrogen in a male? You know, you're
putting me on the spot here, right?
Yeah, but all those things I was
thinking of my particular one particular
person. I think all those things are
true.
So maybe it is like low testosterone. So
my next question becomes is there a way
that they can stimulate their
testosterone without having needles
stuck into them? Absolutely. I mean, the
first thing is you have to look at
lifestyle. What is their diet? You do
need nutrients. If they are not sleeping
and they're um taking potentially
uh recreational drugs, this can all
affect
testosterone. It could be it can affect
sleep. It can affect a number of things.
The first thing that I would do is are
these guys sleeping?
Are they eating well?
Eating well being the protein we talked
about. Are they eating a diet that is
fully processed? Are they training?
Training in and of itself isn't going to
generate testosterone per se, but it
would increase the receptors.
Increase the skeletal muscle receptors.
Increase those androgen receptors.
Uh the other thing that I would say, and
this is what may be a little bit outside
the box, but what are they being exposed
to?
We do a lot of heavy metal testing. Uh
we see we do see a lot of exposures.
Those things can affect fertility.
Whether it's lead or mercury, those kind
of things, absolutely.
And where do these things come from,
these heavy metals?
I mean, we're drinking out of a metal
cup here.
I know. This is stainless steel. I don't
think that this gets into the water.
Um they could certainly get it from
aluminum cans.
They could get it from eating a lot of
seafood. They could have exposures.
Um maybe they're training on weapons.
Maybe not. Could be getting lead. You're
in great shape. Thank you. What do you
eat?
Diet high protein. And I eat a lot of
carbs. I train a lot.
So run me through your day. What time do
you wake up?
Between 5:30 and 6:00. My husband wakes
up at 4:00. Mhm.
So.
And then That's the problem. And then
what do you do?
I get up.
Um I see if the kids are asleep or
awake. Usually one is in the bed, two is
in bed. And then I get ready to go
train.
Get up. Three days a week, I
head over to meet my coach. Sh- shout
out to Carlos Mana. He's the man.
And we hit it hard. And I'm usually 5
minutes late every single time.
Because in the morning,
one or both children will will decide if
they're going to come with me or not. I
include my kids in my training.
How old are they? Three and five.
Oh, damn. You're getting them training
at three and five?
I am.
My 5-year-old is in jujitsu. They have
their own kettlebell sets.
Um
because
people and children,
they don't care what you say.
They care what you do.
So,
sometimes they decide to come with me,
sometimes they don't. Um and I train
fasted.
Wait. I didn't tell you I
caffeinate a lot.
A lot. I am drinking coffee now. I may
be someone who is tired or drinking
water or coffee. How long do you train
for? An hour. And you only do three
times a week?
I do three times a week of lifting.
Okay.
I try to train as hard as I possibly
can.
By that second day, I'm tired.
It would take a lot for me to do some
kind of major lifting. I'm in the middle
of rehab.
The next day, so I'll train Mondays, uh
Wednesdays, and Fridays.
Tuesdays, Thursdays will be
some kind of
light cardio. Maybe I'll do 20 minutes.
Maybe it'll be intense.
Whatever I'm feeling. I'm very active
during the day.
Sometimes I wear a weighted vest.
I take calls walking. I move a lot.
My friends joke that I am someone who
never sits still. Period. End of story.
You can see me now. I'm moving all over
the place.
I have high energy expenditure.
My first meal of the day will either be
a shake. It might be 30 to 50 g of a
whey protein shake. Uh typically, I
might even have collagen in my coffee.
Collagen um in coffee doesn't
necessarily
stimulate muscle, but I use it for hair,
skin, and nails. It's an incomplete
protein and has a protein score of zero.
I just wanted to clarify. So, am I
training fasted? Yes. Uh mostly fasted
might be shot of collagen.
30 to 50 g at that first meal.
I might have some kind of carbohydrate,
but usually
I'm running around. Got to get the kids
to school or whatever it is.
My my next meal might be some lean beef.
I'll definitely have carbs. I'll have
either rice or potato and some kind of
greens. And that will be another you
know, if I were to think about how much
protein, I'm tiny person. I'm maybe 110
lb. I might have 120
g of protein a day.
And then the last meal is also between
30 and 50 g of
protein and probably close to 50 g of
carbs. And what what time is that last
meal typically?
If you can help it. Around 7:00. I eat
with the family.
Nothing crazy. I'm very consistent.
I think it's important that one meal or
one workout doesn't take you off track.
I don't really think twice about it. I
know what I have to eat. Food is not um
complicated.
It's effective.
I don't drink alcohol. I don't like the
way it tastes. I don't really have a
sweet tooth. Is that the only reason you
don't drink alcohol? Because of the
taste? Did you Did you drink alcohol
before?
No. You've never drank alcohol?
No. Taste terrible. I'm sure you've had
it. Taste like rubbing I mean, taste
terrible. Maybe I'm lucky.
But uh also think that
you know, can be toxic for the brain,
but I choose not to have it because I do
think it tastes terrible.
Every single time you eat, you have an
opportunity to improve your health. And
that's why I love Zoe because Zoe helps
me to make the smartest food choices for
me and my body. And as you guys will
know by now, Zoe is a sponsor of this
podcast and I'm an investor in the
company. And if you haven't tried Zoe, I
highly recommend you do because Zoe
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and eat. Which means that I have more
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I'm less hungry. And the most important
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something called the method study, which
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research. I started Zoe just over a year
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checkout.
Are there small parts of your protocol
that people can implement? You talked
there about not sitting.
You know, you said weighted vest.
Yeah. Um are there anything else that we
can do that might help us build muscle
mass without having to go to the gym?
Yes. What are the key things you think
about that? If you can
take a call walking or rocking
you can load up weight. It is extremely
easy to do and you can do it slowly.
Whether you start with
you could start with 7 lb.
I have a 5-lb weight vest. I have a 7-lb
weight vest, 20, and then from there you
can load up weight. So you can build up
over time. Um people should be doing
that. It is effective and easy. Everyone
can do that. People are taking calls.
You don't have to do Zoom call.
Why not? Get on the phone, get moving.
Human body will like to sit, right? As
opposed to be forced to move, but you
become
It's almost like a wrote activity. If
you are someone who is sedentary
it becomes easier to become sedentary
and stay sedentary.
It requires friction to change.
You can mitigate some of that friction
by incorporating movement into your
life.
For example walking with a a weighted
vest, easy.
Training with your kids.
People will say, "I don't have time. I'm
so busy."
Pick up your kids after school. We
instead of go and play video games
we
do a push-up challenge or a dance party.
You know our Have you ever heard of
Texas Hold'em?
The poker game? No, the dance. Have you
ever seen this uh Beyoncé um
made an amazing song called Texas
Hold'em and
I thought she was talking about poker.
She might be, but there is a line dance
associated with that. There are a
million fun ways to do something.
We just have become accustomed to doing
less.
And we'll dance, we'll do whatever,
push-ups, physical challenges, playing
outside get the Nerf guns, whatever it
is.
Easy.
I mean, it couldn't get easier than
that.
What do you think a good goal is to
have? What kind of goal? Cuz I It was a
I've said this before, but there's a
time in my life where my goals are very
like superficial.
Um and they were like
anchored to a a date.
What are the best kind of goals that we
should set ourselves as it relates
relates to our health? I don't think we
should set goals. No goals? I think we
should set standards.
Okay.
When you set a goal, you can either
reach that goal or not. But if you set a
standard then you will always keep your
standard. And that standard will allow
you to reach a goal. But the standard
won't change. For example, the standard
is you wake up and you set whatever that
is, you train every day.
For me, I train 3 days a week.
Um depending on how intense that
training was.
On Saturday, I might do a fourth day of
training. And on Sunday, I forgot to
tell you this, we do a group workout.
My standard is physical activity
has defined moments and that is my
standard, even if I'm traveling.
I know exactly what that's going to be
before I get to the hotel.
That is a standard of physical activity.
I don't have to think about a goal. I
don't have to have a goal of
am I going to hit that or not because I
know that those are things that I won't
fall short of.
My standard is my nutrition plan. I have
between 110 to 120 g of protein. I have
between 110 to 120 g of carbs. I know
what that looks like. That is my
standard.
I don't deviate from that. And what are
you struggling with as it relates to
your own advice?
Um sleep. You're struggling with sleep?
Yeah.
Is that because of the two little kids
or It is. Because I have to make a
choice.
Am I going to spend time uninterrupted
and undivided with them
or am I going to do work?
And my choice is I spend time with them.
And then when they go to sleep, I work
another 2 to 3 hours.
And I should probably do
a better job and know that eventually
everything is going to get done, but I
set standards.
Do you find it difficult? You know, cuz
people always talk about um
not being able to have everything at
once. This is what a lot of women have
said to me. They said they were There
was a time where we were sold this dream
that you could have everything. You can.
You can? I think so. Do you you must see
a lot of excuses in people.
I do. Because it's hard to face the
truth.
And what's the truth?
What is the truth? The truth is
are you doing this
or are you not doing this
because of some kind of internal choice?
There has to be some truth-telling.
And sometimes that truth is
uncomfortable.
And you you can get the job done.
There might be things that um
you have to sacrifice.
But the job that the thing that you want
the outcome that you want, the standard
that you set, it can be done.
It can be done. It's you tell yourself
you can't do it. I mean, I have a three
and a five-year-old.
Do you know what kind of chaos ensues at
my house?
You should come over and I guarantee you
will hold off having any kind of
children for at least 5 years.
But nothing is perfect. It can't ever
Everything cannot be curated. Do I still
get my training in? Do I still get my
nutrition in? Am I anything special? I'm
not.
But my discipline is.
I am very disciplined. Have you always
been? Yes.
A lot of people aren't and they haven't
ever been. It's much more difficult to
not be disciplined.
The reason I am disciplined is to be
able to manage my life. How do I get
your discipline?
You execute. You don't overthink it.
There's nothing to think about. What do
you want?
I want to be like you. No, what do you
want? Where are you falling short?
to be like you.
You would not be nearly as successful if
you were undisciplined. You have to be
disciplined.
I'm just trying to embody the audience.
I'm just trying to trying to think
through all the [ __ ] that people
tell themselves. And we all tell
ourselves [ __ ] in various aspects of
our life. If we're not telling ourselves
[ __ ] as it relates to like exercise,
it's something else. It's our
relationships. It's playing.
Totally. And we all And there's so many
people struggle with personal
responsibility cuz if I was to post if
you were to post or I was to post
anything on my story that you just said
in the last sort of 5 minutes
They'd be very offended. Yeah, and
they'd be Well, not every bit There's a
small group of
So are they going to edit this out so
that I'll come Oh, no, don't Don't send
crazy people after me. No, we will. But
um it's like the what about tree gang.
And the what about tree gang, you could
say anything and they'd say, "Yeah, but
what about Yeah, but what about?" And I
understand some people have they have
legitimate Steven, the truth is
it is very difficult to do what I do. I
run three different businesses. I take
care of some of the most incredible
humans on the planet.
I have my own podcast. I'm writing two
more books. And I don't have full-time
help. I'm a mom.
The one thing I don't find
is I don't find excuses. I figure out
ways to get it done because if it
matters
you find ways to get it done.
You know
if I were to say
and this is an extreme example
but let's say
I said to someone who
I'll just make this up, loved cupcakes.
I said
if you eat another cupcake then
something catastrophic is going to
happen to your dog.
Do you think that they would ever touch
another cupcake? No. Not in a second.
Just like that.
So, the consequence is just not
meaningful enough.
When you find a meaningful consequence
and you understand the consequence of
your actions in that moment,
it becomes easy. And this goes toward
what you're saying about the discipline
and the why part of that equation. You
You refer to that as consequence. Like,
why does this matter to you is the
central part of the equation and deep in
your head somewhere
there's you're so clear on why this
matters. Yeah. Because you've you've
seen the research, you've studied it,
you've seen the the consequence of this.
I've seen the end result. Yeah. You see
people die. You see people
die.
At the end of the day, we are all
health and age and death, these things
nobody's getting out of them.
Like, nobody.
So, if I follow your protocols
for the next 30 years,
at Yeah, then I'll be 60 years old. I'll
be 61 years old.
Can you describe to me what you think my
life will look like as a 61-year-old?
Versus
if I just sit in this chair and eat
processed foods and do zero resistance
training for the next 30 years. Can you
describe the two different Steves? We'll
call it We'll call one sedentary Steve
and we'll call one um
Dr. Lyon Steve.
Okay.
Let's start with
sedentary Steve. Mhm.
I will say
you're 30. So, right now you're
sedentary.
Alzheimer's disease is likely beginning.
Cardiovascular disease is likely
beginning.
Right now at 30? That's right.
Remember, these diseases that we believe
are diseases of aging
are at their core and at their root, in
part,
due to the health of skeletal muscle.
The only organ system that you have
direct voluntary control over.
That's it.
I cannot say, Steven,
"I want your heart to beat at 45 beats
per minute. Go."
I cannot control. You might be able to
control your respiration, but you can't
physically
contract your diaphragm. Go ahead,
contract.
Okay.
Maybe.
It's a muscle.
Skeletal muscle is the only organ system
that you have voluntary control over.
That's it.
Now,
if you decide to not hear what I am
saying,
then
if you are someone
who
has a genetic propensity, maybe you have
I don't know. Uh when you overeat, you
get high triglycerides or you
um
choose not to exercise.
We will start to deteriorate your brain
because
contracting skeletal muscle is an
endocrine organ.
Not only does exercise increase blood
flow to your brain.
Um I just wrote a narrative review with
a colleague of mine, um Louisa Nicola,
amazing.
We looked at the influence of resistance
training and brain function.
I cannot restore your brain, but I'd
love to be able to prevent from the
uh connections
to become weaker and weaker and weaker.
So,
you decide not to exercise, I can do
nothing for your brain.
Eventually,
you might
forget
I don't know.
Your neighbor's name,
your kid's name,
your
um
anything, what you did, any meaningful
memory.
If we don't address
your brain now,
then
the potential outcome is clear.
Right? 2/3 of Alzheimer's,
um the majority of dementia is
Alzheimer's dementia, which plays a role
in
uh metabolic regulation.
Type 3 diabetes of the brain.
If your skeletal muscle is unhealthy,
you are likely having
not only skeletal muscle insulin
resistance, but brain insulin
resistance. No such thing. You cannot
be sedentary and be healthy. So, that
will begin now.
The other thing is your cardiovascular
activity, mhm.
Can't help. Can't help you there. Not
getting increase in blood flow, you're
not um moving
your cardiovascular health the way that
it should, your lung capacity, your
cardiovascular capacity. You're probably
going to be extremely winded walking
upstairs.
It might take so much effort for you to
get up, you might not even be able to
fully
stand up and sit down from your chair
multiple times. You might struggle with
that.
If I said, Steven, "I need you to go to
grab something out of the car for me."
You'd probably say, "Oh, man.
Hey, Doc. Um that's going to take a lot
of effort. I I
I'm not sure. I'm not sure I could even
grab that I don't know, 15-lb grocery
bag."
You um
likely have central obesity.
Probably have sleep apnea, which means
you're further deteriorating both your
brain and your metabolic health.
I would just throw in there you haven't
trained your entire life, your
testosterone is probably low and maybe
throughout your lifespan, who knows?
Maybe you have challenges with fertility
because your sperm quality isn't as good
as it could have been if you were
training and eating well.
Are you convinced yet? So, there's a
there's a link between my fertility, for
men and women, and my muscle mass. There
is um a link between
exercise, training,
metabolic health, and definitely
fertility.
I think we are going to see more and
more literature come out on this.
Muscle mass and fertility.
As um by the time you're 60, we'll
definitely have more.
Is there a link between polycystic ovary
syndrome and muscle mass? You talk about
that I think in chapter two. I think you
There is insulin insulin resistance.
When you think about skeletal muscle and
insulin resistance, skeletal muscle
makes up 40% of your body weight or so.
Depending, for me it might be less, for
you it might be more.
When skeletal muscle becomes insulin
resistant,
again, which means insulin is a
uh peptide hormone that is released from
the pancreas,
you require insulin
to move glucose out of the bloodstream
into cells.
When you exercise, you do not require
insulin to move blood glucose out
of the bloodstream into skeletal muscle
tissue.
It can be insulin independent.
Polycystic ovary syndrome is
multifactorial.
There is a component of polycystic ovary
syndrome that is related to skeletal
muscle insulin resistance.
Once an individual
manages their skeletal muscle mass,
again, there's a various number of
reasons as to why someone would have it,
but
in part, addressing skeletal muscle mass
and skeletal muscle insulin resistance
can help resolve polycystic ovary
syndrome in certain cases.
I was reading on the subject of sort of
um
PCOS and fertility. I was reading a
study by uh which was um done at Harvard
that found that men who reported to
frequently lift heavy weights and
objects at work had a 46% higher sperm
concentration
and a 44% higher total sperm count
compared to those with less physical
jobs. So, you're telling me if I want to
up my sperm count and have a baby,
And health. And sperm health. I should
start lifting some weights. Yes.
I was thinking about the 61-year-old guy
that listens to Dr. Lyon's protocols.
But also,
let's say you didn't We didn't talk
about what would happen if you listened.
Yeah, which is what I'm saying. So, the
guy that listened, so the 61-year-old
Steve Bartlett that listens to your
protocols.
Holy cow, that guy's a beast. He's now
taken over the world.
Because Does he have a six-pack? Of
course he does. Really? At 61? Yes. Is
it possible? Yes.
What's the healthiest
oldest person you've ever seen? My dad.
Really? Oh my gosh.
He's 74. He could put on a little more
muscle. Okay.
His testosterone was like 800. He's not
any hormone replacement.
He has been following what I've been
telling him, unfortunate for him because
I'm his daughter.
He's been listening to this message. I'm
just sitting here with you, but we are
talking about over 10 years
of talking about this,
of seeing this with patients and people.
He has amazing um hemoglobin A1C,
fasting blood sugar,
cholesterol is in check. I mean, he is
strong, he is capable.
He's 74.
What is the most important thing that we
haven't talked about, Dr. Lyon?
I would say that
nobody's getting out of this alive.
And it's all going to come down
to choices.
Choices for how
we execute.
Our present choices will determine our
outcomes.
And it is not difficult, it's not
complex.
You have to prioritize skeletal muscle.
This is the organ of longevity.
With this physical framework comes
mental strength.
And what's most important about this
isn't for us now.
Like, this is great, you can do it,
but it provides
hope and an example for our children.
That them, those people, the little
ones, that is who I am
truly worried about
because we have normalized supersizing
everything including ourselves.
We have more electronics than ever
before. We are more disconnected from
people.
People will say the internet has done a
great job at connecting. Face-to-face
conversations, connection is huge.
The most important is our youth and how
we raise them and the messages that we
give them
because they are our responsibility. And
if we cannot advocate for our own
health, whatever those limitations are
whether it's personal or worthy, it is
our responsibility to do a much better
job
so that we not tell them but we show
them the way forward.
And what's the most important subject in
your book that we haven't covered?
Forever Strong, a new science-based
strategy for aging well, how to reboot
your body to burn fat, fight heart
disease, reverse diabetes, stay sharp,
build muscle, and boost energy.
I mean, we talked about dietary protein.
We talked about how that potentially can
be controversial controversial for some
people.
Um
We discussed carbohydrates.
Carbohydrates are earned through
activity.
If someone is metabolically unhealthy,
they have to understand that potentially
starting with 100 g and titrating up or
down depending on their activity level
is important.
How quickly do I lose muscle?
Uh you if you are in the ICU, you could
lose 2% of your muscle mass in a day.
Ugh, god, what?
If you are in a highly catabolic state
on bed rest,
you will lose muscle
rapidly
depending on your age.
Um within 7 days, you could lose if
you're young and healthy 2 lb of
skeletal muscle mass.
Cuz I'm thinking if I go to the gym
today and I did my biceps and I really
smashed it,
how long before those gains were lost?
I would give you you'll lose strength
and then mass.
Um you will lose it rapidly. 7 days of
bed rest,
you will lose it.
And and But it will return if you've
been well trained.
And it will return faster the second
time than it did the first time, right?
People talk about muscle memory a lot.
That is a interesting
perspective. Yes, if you are well
trained, will it return? Yes.
It also depends on how long you've been
untrained for. It also will depend on
how highly catabolic you are.
For example, if someone had cancer,
they're in a highly catabolic state,
their body is breaking down, skeletal
muscle mass will improve their
survivability.
If someone goes on bed rest, you will
lose muscle mass and strength extremely
rapidly.
Now,
will you able to improve
re-return insulin sensitivity? Yes.
If you decided to just begin
basic activities of living and not
exercising, you will not be able to
recover that muscle. Getting out of the
hospital, just doing basic things will
not be enough.
And now as you can imagine, that happens
to people.
I can imagine. Yeah.
Yeah, I go through periods in my life
where for whatever reason I have to be a
bit more sedentary.
Um
things like filming TV shows. I filmed a
show called Dragon's Den where we
basically sit in a room for 10 hours a
day. It's like Shark Tank here.
And whenever I go through that season of
life, it's very difficult. I I I always
see this correlation between how much
activity I have I've been doing and how
much motivation I have.
Uh so if I've been sat down and not been
exercising for a while, I find it harder
to find the motivation to go again and
it's this kind of vicious downward
spiral.
One thing that we didn't talk about is
how skeletal muscle mass
functions as an endocrine organ.
What's an endocrine organ? An endocrine
organ is something that produces
hormones that act systemically, locally,
and um inter or there's an inter organ
connection. When you exercise based on
intensity and duration, you release
myokines. Myokines like interleukin-6 or
interleukin-15.
These are what people typically think as
cytokines that are released from
inflammatory cells or macrophages.
But when you contract skeletal muscle in
a meaningful way based on the intensity
and duration, you release myokines from
skeletal muscle that interface with your
brain. They affect mood. They affect
neurogenesis. It also affects your liver
and your kidney. There's this inter
organ cross talk. You know, we talked
about skeletal muscle about how
important it is from a metabolic
perspective, as a body armor
perspective, but also as this endocrine
organ that can affect mood because of
the components that it's releasing.
And that is fascinating. It can
counterbalance inflammation
based on the activity duration
and intensity. So that explains why if
I've not been moving, I don't feel as
good in terms of motivation and um
I feel more fatigued when I've done less
exercise over a long period of time. I
mean, yes. And it doesn't take much to
maintain what you have. For example, if
you could during those days,
do you have to be So you're shooting for
10 hours, you don't have breaks?
We have lunch break.
You should be training on that lunch
break. I don't care how tired you are.
I'm hungry.
Then
you should eat in 10 minutes and get to
training.
It's a good point and you're totally
right. Push-ups, have a weighted vest,
do whatever you have to.
You will feel exponentially better.
And also this is predictable. So here is
an example. You know it's coming, right?
You know that you'll be filming this for
10 hours a day. Yeah. What is your
strategy to execute in a way that is
effective and meaningful? And that's
really it, isn't it? It's about forward
planning. Yeah.
You know it's coming. It's predictable.
It's also predictable how you're going
to feel
afterwards. And then you are going to
have to account for how you feel and
then you are going to have to deal with
the repercussions of now not being
motivated, now having to address your
diet, and now probably feeling a little
bit more down than you would have. We
totally know it's coming. It's one of
the big things I've just real- realized
as you're talking is I don't schedule my
workouts.
So my workouts are kind of this residual
residual beneficiary. I either get
whatever time's left over in the day,
which might mean last night it was super
late. It was almost at midnight.
And then today I've got a flight off to
this. So it's a 10-hour flight. So it's
like
but I I could quite easily I have the
fortune and privilege of just being able
to ask my assistant to change something.
So I can say, "While you schedule
everything else, also schedule an hour
for me to train." But I think everyone
could probably do that. I would I wonder
how many people schedule their workouts.
Everybody who is
You show me your habits and I will tell
you how successful you will be able to
continue to be in the long run.
You could probably look at someone's
calendar and figure out what they're
going to look like in 10 years' time.
I definitely can.
But I will say that there's this
privilege of youth and then there
becomes a tipping point.
Yes, you should be scheduling those
things. You can And let's say you say to
me, "Gabrielle, I don't have time to do
it."
You are not You could schedule 3 days a
week. You know that we're filming all
day. You know that you're doing these
things.
That is a non-negotiable because you're
setting a standard. You set a standard
for everything in here and everything
else you do. Mhm. Nothing is going to be
more critical
for your impact than being able to
manage your health because again, there
comes a point in time where
um
it's a very predictable
turning point, inflection point.
If we get together again and I don't
know, say it was 30 years from now and
I say to you you know, how
and you've been successful over the next
30 years, however you define that. What
happened?
We've completely changed the
conversation.
We are no longer
at nauseam. I'm talking about obesity.
That is a side component.
We are focused
on physical and mental strength. We are
focused on understanding that it is a
muscle problem and a problem and a
solution that we can do something about.
Obesity is an afterthought.
And personally?
My kids have done amazing.
They're happy and adjusted and can
withstand whatever whatever comes their
way. And my husband will be picking up
his socks.
If he stopped taking care of himself,
You would never. He doesn't even He
would never. No, but just say play out
the scenario. Yeah.
Would you say something to him? Uh yes.
What would you say?
I don't want to put it on camera, but
it'd be something totally inappropriate
and somewhat aggressive, but yes, I
would say something to him.
But ultimately,
he has to be an example for our kids. It
is his responsibility. It's not about
him.
We have a closing tradition on this
podcast where the last guest leaves a
question for the next not knowing who
they're going to be leaving it for.
And the question that's been left for
you is
regret can occur
due to action taken or action not taken.
In light of that,
what is your biggest meaningful regret
and why?
My biggest meaningful regret and why?
I don't know if I have a regret.
I don't know if I have a regret that I
can think of
because I think that we are responsible
for our choices. What if I put the word
mistake in there?
I mean, the only thing that I could
think of is
I
Again, this isn't a mistake or I don't
even know if I consider this meaningful
is that
um
outcomes unfold
and instead of you know, I was so driven
and I've been so driven by
doing good. You know, thinking like
I have to contribute. I have a
responsibility to contribute to the
world.
I could have put a lot less pressure on
myself, but is that
is that meaningful? Is that a meaningful
regret or a mistake? I can't say that
that's true.
Would the outcome have been any
different?
Would I have worked any less more
diligently? I don't know.
Well, it's a good thing you have because
um you've really led the charge as it
relates to muscle and the conversation
around muscle and these subjects more
broadly. But when I think of someone
that is at the very forefront of
educating the world on muscle and its
importance and especially as we age that
we can be
forever strong um at least strong while
we're still alive, then that person is
you. And I can't imagine how many
millions of people are better for that.
I can't imagine. It'd be crazy if you
could put them all in like a stadium or
something and and get to meet them all
that just had their lives just subtly
altered. Even if it's just, you know,
one decision to go for a walk or to do a
little bit more resistance training once
a week. That matters, right?
And that's a really wonderful thing. And
that's I kind of guess what your your
all of your work is really aiming at is
to find, understand someone, but then
give them the the missing piece of
information or inspiration so that they
can pursue their very best self. And I
thank you for doing the work that you do
because
I I'm sure those millions of people
can't thank you themselves, but it's um
it's really altering not just their
lives, but also as you say the
generations that are set to come after
them and their children and so on. And
that's one of the things I'm actually
thinking much more about having spoken
to you is the I've never thought because
I don't have kids yet about the role
models that I that I am or aren't to
those kids that are watching me. And as
you said it, I had a little flashback of
my mom outside my house when I was like
a a four, five year old and just
watching her run up and down the street
um over and over again in this tiny
little sort of circle that she used to
do and how that stayed with me for
forever. That she cared about that. And
that what that meant for us is um how
children
And it's a really powerful thing. It's a
really wonderful thing cuz you know,
this isn't really about muscle at the
end of the day. This is
about much more It's not
medicine is the gateway to really be
able to provide freedom for people.
That's what I want. Mhm.
Muscle is the way in. Medicine is the
way in, but what I really want for
people
is I want them to have freedom.
And that freedom is happiness. It is.
Yeah, or whatever it is that they want
to do. Mhm. Thank you so much. It's such
an honor to meet you. Thank you for
having me.
[Music]
Isn't this cool? Every single
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[Music]
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Ask follow-up questions or revisit key timestamps.
This video features Dr. Gabrielle Lyon discussing the vital role of skeletal muscle as the 'organ of longevity.' She challenges the traditional focus on obesity, arguing instead that building muscle mass and physical strength are the true keys to long-term health, disease prevention, and performance. Dr. Lyon explains that resistance training and adequate dietary protein are essential for maintaining muscle health as we age, countering the common belief that frailty is an inevitable part of growing older. Beyond the physical, she emphasizes the importance of 'worthiness' and mindset in maintaining discipline, explaining how our daily choices and interpretations of stress directly dictate our health outcomes.
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