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The Exercise Neuroscientist: NEW RESEARCH, The Shocking Link Between Exercise And Dementia!

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The Exercise Neuroscientist: NEW RESEARCH, The Shocking Link Between Exercise And Dementia!

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2525 segments

0:00

In this box is a real preserved human

0:03

brain named Betty. And I think you

0:05

should hold it.

0:07

Oh my god, it's wet.

0:09

And now we're going to go through all

0:11

the tools and tricks to make your brain

0:13

as healthy as it can be. Are you ready?

0:16

Wendy Suzuki, the neuroscientist and

0:18

professor at New York University.

0:20

Her first-hand research on the brain is

0:22

helping to improve memory, learning, and

0:24

higher cognitive abilities in humans.

0:27

Let me start with exercise.

0:28

All the research shows the more you

0:31

exercise, the more change in your brain

0:34

we notice. Every drop of sweat counted.

0:36

And the best kind of exercise that you

0:39

can do is

0:40

What about things that we consume? Food,

0:42

drink, and alcohol.

0:43

It's all the Mediterranean diet. Go

0:45

ahead.

0:45

Coffee.

0:49

And then my memory's not great.

0:50

Most people feel that. But there's four

0:52

things that you can do to make memories

0:54

stick. Number one is

0:56

Is it true that if we have less friends,

0:58

then our brain will shrink?

1:00

Yes, loneliness damages the brain.

1:02

Can you see if someone's in love in the

1:03

brain?

1:04

Yes, in the side here. A lot of the

1:06

reward areas are activated.

1:08

Doesn't that mean then that if we don't

1:09

fall in love, the love part of my brain

1:11

gets smaller? And would that make it

1:12

more difficult to love in the future?

1:14

That's a great question. So

1:16

Wendy, do you have any brain routines?

1:19

Absolutely. So every morning I like to

1:22

Oh, and then I do the most powerful tool

1:24

that you can do to protect your brain

1:26

from aging and neurodegenerative disease

1:28

states, which is

1:31

We've just hit 6 million subscribers on

1:33

the Diary of a CEO. Um, so me and my

1:35

team would like to do something we've

1:36

never done before as a little thank you.

1:38

And we're calling it the Diary of a CEO

1:39

subscriber raffle. And here is how it

1:41

works. Every episode this month, we're

1:43

going to pick three current subscribers

1:45

at random, and we'll send one of you a

1:47

£1,000 voucher, one of you tickets to

1:49

come and watch the Diary of a CEO behind

1:50

the scenes live with our team, and one

1:52

of you will have a 10-minute phone call

1:54

with me to discuss whatever you want to

1:55

talk about. If you're a subscriber,

1:58

you're in the raffle.

1:59

Thank you from the bottom of my heart

2:01

for allowing me to do something that me

2:03

and my team love doing so much. It is

2:05

the greatest honor of my lifetime, and I

2:06

hope that I hope it continues off into

2:09

the future. Let's get to the episode.

2:18

You just said to me that much of your

2:20

work is focused on making sure people

2:21

have big, fat, fluffy brains.

2:24

Yes.

2:25

Why does that matter?

2:26

It matters because a big, fat, fluffy

2:29

brain is a healthy brain, and

2:33

my whole first book, Healthy Brain,

2:35

Happy Life, was about how I learned to

2:37

use all the tools and tricks and magic

2:41

of neuroscience and psychology to make

2:44

my brain work better, and I so needed it

2:47

at that moment. My life got better. I

2:50

got happier. It is a pathway to a happy

2:53

life, I think.

2:54

Having a very healthy, big, fat, fluffy

2:57

brain.

2:58

Do you think people appreciate the

2:59

importance of their brain?

3:00

No. I think they ignore it all the time.

3:04

And I think that is part of my part of

3:07

my message to everybody that that the

3:10

human brain, that is the one in your

3:12

head right now, is the most complex

3:14

structure known to humankind. Not

3:16

Einstein's brain, not Marie Curie's

3:19

brain, but the one in your head. And

3:22

when you think about that, it gives you

3:25

more of a self-appreciation

3:27

of all of the computations that is

3:30

taking for me to see you and appreciate

3:33

your face and be able to remember your

3:35

face next time I see you when I go to my

3:38

Diary of a CEO podcast and and choose an

3:41

episode, all of that is is such a

3:45

complex structure. Um you start to

3:47

appreciate your own kind of brain

3:49

functioning more. I think that's a very

3:50

important thing to do.

3:52

Why don't we appreciate our brains? Cuz

3:54

we appreciate a lot of other things.

3:55

Yeah.

3:56

We spend a lot of time on our like our

3:57

muscles.

3:58

Yeah, our abs.

3:59

Yeah.

4:00

I think that that's a great analogy and

4:03

part of my goal is to kind of shift the

4:06

focus from focusing on certain body

4:09

parts to focusing on what our brain is

4:12

doing for us, what it can do for us, and

4:15

what we can do to change our

4:17

environments to get to that big fat

4:19

fluffy brain, to get it healthy, to get

4:21

it happy, to get it growing.

4:23

If I achieve a big fat fluffy brain,

4:27

how would my life be different? I'm

4:29

saying me, Steve Bartlett. I'm a

4:30

podcaster, I'm an I'm an entrepreneur,

4:32

I'm

4:32

relationships, I've got friends,

4:34

girlfriend, family. How would I show up

4:36

differently if I was able to make my

4:39

brain big, fat, fluffy?

4:40

Yeah. So, uh let me start with the two

4:42

areas that we know respond really,

4:45

really well to things like meditation

4:48

and exercise. Those two brain areas are

4:50

the hippocampus, critical for long-term

4:53

memory, your ability to form and retain

4:55

new long-term memories and for facts and

4:57

events. And the second brain area is

4:59

your prefrontal cortex, right behind

5:01

your forehead, critical for your ability

5:03

to shift and focus attention. Um it's

5:05

important for your personality, for

5:07

decision-making.

5:08

Can you show me on there? Is it you

5:09

brought

5:10

Absolutely. I brought a human brain.

5:11

You You have

5:12

that.

5:13

a model of a brain as well.

5:14

a model of the brain. Okay, let's start

5:15

with the model of the brain.

5:20

So, here is a model of the human brain.

5:23

So, there's a front part and a back

5:25

part. This front part is right behind

5:28

our forehead. That's the prefrontal

5:29

cortex, critical for the ability to

5:32

shift and focus attention. Also, a part

5:35

of the brain that is very responsive to

5:38

what you bring into your life. Exercise

5:41

actually really helps the prefrontal

5:42

cortex. Meditation

5:44

helps area 10 of the prefrontal cortex,

5:46

which is right in the very front, right

5:49

here. The second brain area that you

5:51

will benefit from when you make your

5:54

brain big and fat and fluffy is a

5:56

structure called the hippocampus, which

5:57

is which is very deep in this lobe,

6:01

deep in this lobe right here, which is

6:03

the temporal lobe. The hippocampus

6:07

Hippocampus means seahorse, and the

6:09

hippocampus is critical for your ability

6:12

to to form and retain new long-term

6:15

memories for facts and events. You have

6:16

one on the right and you have one on the

6:17

left. So, for you,

6:20

superstar podcaster, what do you need to

6:23

do? You need to remember all the details

6:25

of that guest that you're sitting in

6:27

front of. You need to be able to focus.

6:29

What did they say? What do I want to ask

6:31

next? And how do I want to come back to

6:33

those things? That is a combination of

6:35

what your prefrontal cortex is doing for

6:36

you and your hippocampus is doing for

6:39

you. So, I submit that you, when you do

6:43

these things that we know from

6:44

neuroscience, are going to make your

6:47

prefrontal cortex and your hippocampus

6:48

big and fat and fluffy, you will be

6:51

better at doing your job as a podcaster.

6:54

I am better as a dean and a professor of

6:57

neuroscience and and teaching in class,

7:00

for example, is where I'm using my

7:01

prefrontal cortex and my hippocampus the

7:03

most. Most of us would benefit from

7:06

these things that make our brains big

7:08

and fat and fluffy.

7:09

Was there a point in your life where you

7:11

had a personal epiphany or revelation

7:14

about the brain that made you so

7:16

passionate about the subject?

7:17

Absolutely. Absolutely. So, this story

7:21

starts when I was in the middle of

7:24

getting tenure um at New York

7:26

University. So, it takes six years. Uh

7:28

you have six years to prove yourself as

7:31

a scientist and do something

7:32

groundbreaking. And if you don't, you're

7:35

fired. So, no big deal. No pressure

7:37

there. And I decided to only just work.

7:41

Work, work, work. I didn't have a lot of

7:43

social interactions. I was just working

7:45

and I just just threw myself into work.

7:48

And I was getting burnt out. And

7:51

I decided to go on a river rafting trip

7:54

to Peru

7:55

by myself cuz I had no friends. So I go

7:57

on the river rafting trip and it's

7:59

great. It's beautiful. We're river

8:01

rafting. We're we're camping on Aztec

8:04

burial sites and it is just spectacular.

8:08

But I realized that I'm the weakest

8:10

person on this trip. And when I got back

8:13

after this wonderful, you know, two

8:15

weeks in Peru,

8:17

I said I never want to feel like the

8:18

weakest person on a trip like that

8:20

again. And it was so great to to be

8:23

moving and to be exercising. So I

8:25

decided I'm going to go to the gym and

8:27

I'm going to continue this

8:29

physical activity at the gym. And

8:31

somehow it stuck. I had I had let myself

8:34

go, not no exercise at all. And when I

8:38

started going to the gym regularly, I

8:40

noticed that that great mood that I

8:43

found in Peru every day during the river

8:45

rafting trip stayed with me. I think

8:48

everybody in my lab loved it when I was

8:50

going to the gym. And I started to

8:52

notice not only I got stronger, I was

8:54

feeling better,

8:56

that mood boost that I got from physical

8:58

activity was so powerful. But then one

9:02

day this you asked me about this

9:04

revelation I had. It was one day I was

9:06

sitting in my office

9:08

writing a grant,

9:09

which is usually something that I have

9:12

to do very regularly, but usually

9:13

something that I'm pulling my hair out.

9:15

It's so hard. It's very competitive. I'm

9:17

competing against Nobel laureates for

9:19

the same pot of money.

9:22

And I had this thought that went through

9:23

my mind, which was

9:25

gosh, writing

9:27

went well today. I I'd never had that

9:30

thought before ever in my I had been

9:32

there for five years at at NYU writing

9:34

grants. And so um, I um, I thought, "Oh,

9:39

maybe maybe I'm just having a good day.

9:41

I'm feeling good."

9:42

But I realized that the um,

9:45

the writing seemed to have been getting

9:47

a little bit better over time. I had

9:49

noticed it a little bit if I think about

9:50

it. And the only thing I had changed in

9:53

my life was regular physical activity

9:56

inspired by that trip to Peru.

9:59

And so, I'm a neuroscientist. I went to

10:02

the literature and I asked, "Well, what

10:03

do we know right now about what exactly

10:05

exercise is doing?"

10:07

And it showed at that moment in time,

10:09

about 10 15 years ago,

10:13

that exercise can improve your mood,

10:16

exercise actually makes your memory work

10:19

better, and exercise improves the

10:21

function of your prefrontal cortex. And

10:23

I thought, "Wow, that that is amazing."

10:27

But the last part of the story was that

10:30

when all of this was going on, this was

10:32

after this day of realizing, "Gosh,

10:34

something's you know, my writing is

10:36

better and um, maybe it's exercise." Um,

10:39

I got a call from my mom who said that

10:42

my father wasn't feeling well and that

10:45

he had gotten lost driving back from the

10:48

coffee shop that he drove to every day,

10:51

every afternoon for the last 20 years.

10:54

And the hippocampus, that structure

10:56

critical for memory, is particularly

10:58

important for spatial memory. And as an

11:02

expert in the hippocampus, as I am, I

11:04

knew that that was a telltale sign of

11:07

dementia and maybe Alzheimer's dementia.

11:11

But as I talked to my father and of

11:13

course we went and got him uh, neurology

11:15

appointment, I saw that everything that

11:18

seemed to be improving in me, that is

11:20

memory, focus,

11:23

completely and very very suddenly uh,

11:26

diminished in him. His memory was

11:28

terrible. He couldn't focus. He was also

11:31

very depressed because he could notice

11:33

how poor his memory was.

11:36

And I think those things together, what

11:39

I was noticing in myself about the

11:41

physical effects of the effects of

11:43

physical activity on my own brain

11:45

function, and seeing my father go

11:47

through which what was a really

11:50

precipitous loss of his cognitive

11:52

functions, that turned out to be

11:54

Alzheimer's dementia.

11:56

Made me think that the power of physical

12:01

activity needed to be explored more

12:03

deeply.

12:04

And by me. I I was waking up in the

12:07

morning thinking about what can we what

12:09

can I do to better understand how

12:11

physical activity could be used not just

12:13

for me, for my students? Can they study

12:15

better? Can they learn better? Can it

12:17

help maybe not my father, I wasn't sure

12:20

whether exercise could help my father at

12:21

that point, but as people age, that was

12:25

the revelation that I had that made me

12:28

actually switch my research focus from

12:31

memory function to understanding the

12:34

effects of physical activity on the

12:36

brain.

12:37

All of this is rooted in a

12:41

fact that was once not considered a

12:43

fact, which is the idea that our brains

12:45

can change shape.

12:46

Yes. Yeah.

12:47

Which is this idea of brain plasticity.

12:48

I mean, I really learned about this a

12:49

couple of years ago cuz I think I, like

12:51

many people, didn't realize that like

12:53

muscles, my brain changes shape based on

12:55

what I do.

12:56

Yes.

12:57

And also what I consume.

12:59

Yes.

12:59

I guess.

13:00

Yes.

13:00

What is the evidence for the studies

13:02

that we have that proves our brains do

13:03

change shape?

13:04

Yeah, that's such a great question and

13:06

uh it takes me back to the first day of

13:08

my freshman year at UC Berkeley. When I

13:11

walked into the classroom, I didn't know

13:13

at the time, but the classroom of the

13:15

professor that discovered brain

13:17

plasticity. Her name is Marian Diamond

13:20

and she was the very first female PhD in

13:23

neuroanatomy that UC Berkeley ever gave.

13:26

Um I walked into her classroom in the

13:29

'80s when I went to college, but she

13:31

discovered this in the late 1960s.

13:35

Um, when it was thought, as you said,

13:37

that the adult brain can't change at

13:39

all. There's absolutely no evidence for

13:41

it. And that was true at the time. She

13:43

thought, "Hmm, I don't think that's

13:45

true. Let's Let's do a simple

13:47

experiment. Let's try and um

13:50

uh look at the effects in two randomly

13:53

grouped set of rats. One that lives in

13:56

what they would consider an enriched

13:58

environment. What would be an enriched

14:00

environment? Well, for her, it was a rat

14:03

cage full of toys that got changed out

14:05

all the time, lots of other rats to play

14:07

with, and um lots of lots of activity. I

14:11

think of it as the Disney World of rat

14:13

cages. And she compared the brains of

14:16

those rats to rats that she raised in

14:18

kind of a shoebox, a smaller

14:20

environment. They got free food and

14:21

water, all the food and water they could

14:23

eat and drink, but maybe only one other

14:25

rat and no toys.

14:27

Now, if the adult brain They were all

14:28

the same age, they were adults. If the

14:31

If the adult brain didn't change, then

14:32

there should be absolutely no difference

14:34

between the brains raised in Disney

14:36

World and the brains raised in the

14:38

shoebox. But she found that the

14:41

the brains of those rats raised in the

14:43

Disney World of rat cages, the outer

14:46

covering of the brain, the outside of

14:48

the brain here, I'm pointing to the

14:50

outside of this brain model here, called

14:53

the cortex, it was actually thicker. She

14:56

was She was a neuroanatomist, and she

14:58

showed that the thickness of this outer

15:00

covering actually grew. What does that

15:02

mean? There were more synaptic

15:04

connections there. In Not in the whole

15:07

brain, in certain brain areas. That made

15:09

sense. The visual cortical area. There

15:12

was much more visual stimulation in the

15:14

Disney World of rat cages. The motor

15:16

areas were thicker. The somatosensory,

15:18

the touch areas were thicker because

15:20

they were interacting in a much more

15:21

complex way with their touch system.

15:26

And that was the first demonstration the

15:28

adult brain could change, and that it

15:31

would actually make the cortex of the

15:34

brain grow.

15:36

And now we know, what is it about the

15:38

Disney world of rat cages, you know? Um,

15:41

is it the toys? Should we all be playing

15:43

with toys? Later studies showed that you

15:46

get almost identical effects just by

15:49

giving rats a running wheel.

15:52

Physical activity is doing all of that,

15:55

has the potential to change all of that

15:58

in the rodent brain, and now in the

16:00

human brain.

16:01

Didn't they find something similar with

16:02

um, London taxi drivers? I always hear

16:05

this. I I thought it was like a wasn't

16:07

sure if it was true or like a rumor, but

16:09

no. It's absolutely true. That is a

16:11

different form of brain plasticity,

16:14

which is something that we all do, and

16:15

my students do hopefully very well,

16:17

which is learning.

16:18

So, can learning the streets of London,

16:22

which are I can't remember the the the

16:24

number of different streets that London

16:27

taxicab drivers have to learn to pass

16:30

the famous test called the knowledge,

16:33

but I do remember that it takes them 4

16:35

years to study for this test. It is

16:39

intense

16:40

uh knowledge. You have to learn all the

16:43

lawful ways to get from all the big

16:45

landmarks to be a certified London

16:48

taxicab driver. And what uh my colleague

16:51

Eleanor Maguire, uh professor of

16:53

neuroscience at University College

16:55

London, did is she followed wanna-be

16:59

London taxicab drivers during their 4

17:02

years of the knowledge, this test for

17:05

London taxicab drivers, knowing that

17:07

half of them were going to fail. They're

17:09

they're they were not going to make it.

17:11

And so, she tested them at the beginning

17:13

and asked, "How is your memory?" Uh, and

17:16

how big is your hippocampus?

17:18

Identical for all all of the wannabe

17:21

London taxi cab drivers before they

17:23

started.

17:23

She scanned their brains.

17:24

Yeah, she scanned their brains and she

17:26

tested their memory.

17:27

Okay.

17:28

Behaviorally.

17:29

Then they go through, half of them drop

17:31

out, they don't become London taxi cab

17:33

drivers and half of them become

17:35

certified London taxi cab drivers after

17:38

successfully learning all of this. Now

17:41

let's see, how big is your hippocampus

17:43

and how good is your memory? The people

17:45

that passed the test and became London

17:48

taxi cab drivers, the posterior part of

17:50

their hippocampus, which is the part we

17:52

know is important for it with posterior

17:54

is back towards the back of the head,

17:57

the posterior part of the hippocampus,

17:58

which is kind of a cigar-shaped

18:00

structure that goes from the front part

18:02

of the brain to the back part of the

18:03

brain, that back part of the brain was

18:06

significantly bigger in those London

18:10

successful London taxi cab drivers

18:12

compared to the failed London taxi cab

18:16

drivers. And the memory of the

18:19

successful London taxi cab drivers were

18:21

now superior to the memory of the

18:24

wannabe London taxi cab drivers that

18:27

failed. So that is an example of how

18:30

intense learning in a particular part of

18:33

the brain,

18:35

we know the posterior hippocampus is

18:36

absolutely involved in spatial learning,

18:39

that can change the actual structure and

18:42

the function.

18:43

How much of a difference can we make?

18:45

I'm 31 years old now.

18:47

Yeah.

18:47

So if I got serious about my brain

18:50

health,

18:50

Yeah.

18:51

how much of a difference can I

18:53

realistically see?

18:55

You know, I'm trying to figure out if

18:56

it's worth it.

18:57

Yeah.

18:57

If it's worth caring about my brain.

18:59

Mhm.

19:00

Is Is there any evidence within the

19:02

literature, within studies that have

19:03

been done that show if I start now, even

19:06

though I'm like 30 31 years old,

19:08

my life will be different in the future

19:10

in the areas that I care about

19:12

profoundly if I start caring about my

19:14

brain.

19:16

Let me be very very um

19:19

um concrete here. The answer is

19:21

absolutely yes. First, I'm going to give

19:23

you results of a study in people that

19:25

are 65 and older. So, study people that

19:28

are 65 and older

19:30

and asked, "What is the probability of

19:33

getting dementia in the next 6 years

19:36

depending on the level of activity that

19:38

you have just right now?"

19:40

Physical activity.

19:42

And they measured it in how many walks

19:43

you take per week.

19:45

And if you took three walks a week or

19:48

more,

19:50

you were 30% less likely to develop

19:53

dementia in the next 5 years.

19:57

So, ooh, 30%

19:59

uh less likely to develop dementia. My

20:02

father passed away of Alzheimer's

20:04

dementia. That makes me sit up and take

20:07

notice. But the But the thing that

20:09

should make you as a 31-year-old uh

20:12

really sit up and take notice is the

20:14

larger correlations that show that the

20:17

longer you have regular physical

20:19

activity in your life, the longer you're

20:22

able to stave off dementia. The more

20:25

active you are over your lifetime, um

20:29

that first study shows that it's never

20:30

too late to start. You can start walking

20:32

regularly, which is doable when you're

20:35

uh perhaps at that age. But the longer

20:38

you stay active, the bigger and fatter

20:41

and fluffier your brain will be. Why

20:44

does that make sense? So,

20:46

one key piece of information that I

20:47

haven't told you yet

20:49

is that we know that physical activity

20:53

is releasing a whole Every single time

20:55

you move your body, you're releasing a

20:57

whole bunch of neurochemicals in your

20:59

brain. Some of them make you just feel

21:01

good. Serotonin, dopamine,

21:04

noradrenaline, endorphins. Yeah, I feel

21:06

good. If I go out for a walk, I feel

21:07

better than if I had been sitting here

21:09

for 8 hours. But, the other thing that

21:11

gets released every single time is

21:13

growth factors. I like to call it a

21:15

bubble bath of neurochemicals that

21:17

happens every time you move your body.

21:21

What that

21:22

growth factor does is it goes directly

21:25

into your hippocampus, and it helps

21:27

brand new cells grow in your

21:29

hippocampus. The hippocampus is only one

21:31

of two total brain areas where new cells

21:35

can grow. That's not the same as

21:36

synapses, which are connections in the

21:38

cells that are already there. But, the

21:40

hippocampus can grow new cells, and this

21:43

is really important because many people

21:46

know that the hippocampus is attacked

21:48

first in Alzheimer's dementia.

21:51

And so, exercise is not going to

21:54

eliminate that disease state, but if you

21:57

start with a huge, fluffy hippocampus,

21:59

it's going to take that disease that

22:01

much longer to actually damage enough of

22:04

your hippocampus so that you start

22:06

seeing those telltale signs of memory

22:08

impairment that comes with Alzheimer's

22:11

disease and and dementia in general.

22:13

Same thing with the prefrontal cortex.

22:15

Your prefrontal cortex can grow with

22:18

physical activity. That's not neurons,

22:20

but new synapses can grow.

22:23

Age and neurodegenerative disease states

22:25

can damage cells, but also take away

22:27

synapses.

22:28

I got two questions on that. So, the

22:30

first is about dementia and Alzheimer's.

22:32

Do we know what's causing it?

22:33

No.

22:34

We still don't know.

22:35

No.

22:36

And there's not

22:38

good drugs, unfortunately, right now.

22:42

There's a lot of links to lifestyle

22:43

choices there, right?

22:44

Yes, absolutely.

22:46

And so, of course, from based on what I

22:48

just said, my number one most powerful

22:52

tool that you can do to protect your

22:54

brain from aging and neurodegenerative

22:57

disease states is start walking.

23:00

Why do I start with that? Because

23:01

everybody can walk. You don't need to

23:03

buy any new fitness outfits. Just go out

23:07

and walk more. And then they say, "Oh,

23:09

well, do I have to become a marathon

23:10

runner?" That could help, too.

23:12

But everybody can walk. And from that

23:15

study that I mentioned in the

23:16

65-year-old, si- 30% reduction in um the

23:21

probability of getting Alzheimer's with

23:23

just walking.

23:24

You said that if I go and start walking

23:27

and I do exercise, my prefrontal cortex

23:29

will grow.

23:30

Which is the decision-making center,

23:32

right?

23:32

Yes.

23:33

So, does that mean then that if I am

23:36

somebody who is very sedentary, I don't

23:38

do much physical activity,

23:39

Mhm.

23:40

that my decision-making will be worse

23:42

compared to what it could be with the

23:44

same person if they were active?

23:45

Yes. I mean, that there is that

23:48

potential. Brain plasticity and the

23:50

neuroscience of brain plasticity tells

23:52

us that absolutely with physical

23:54

activity, uh you have great potential to

23:57

improve the function of your prefrontal

23:59

cortex. And I must specify a little bit.

24:02

Uh the main function that is um that has

24:05

been shown to be particularly sensitive

24:07

to regular physical activity is um

24:10

shifting and focusing your attention.

24:12

So, being able to um listen to me while

24:15

you might be paying attention to uh the

24:17

AV guy that might be telling you

24:18

something right now. So, to be able to

24:20

do that effectively, uh that that is one

24:23

of the things that we know is helped

24:25

with regular physical activity.

24:26

Focus and attention, that kind of thing.

24:27

Okay. You talked about memory as well.

24:29

Does that Does that exist in the

24:30

prefrontal cortex as well?

24:31

Uh there's a form of memory, working

24:33

memory, uh which is kind of scratchpad

24:35

memory. It's a memory that um when we

24:37

used to have to remember telephone

24:39

numbers, that that the ability to

24:40

remember a seven-digit, at least in the

24:42

United States, telephone number. It's

24:45

different from long-term memory

24:46

formation, which is memory for facts and

24:49

events uh that is dependent on the

24:51

hippocampus.

24:53

I feel like my memory is not great.

24:55

Most people feel that.

24:57

Why is my memory not as good as other

25:00

people?

25:02

Because I I noticed this when I I was

25:04

with my friend in um Thailand many years

25:05

ago. I think I was 21 years old and we

25:08

could like leave the house and go on our

25:10

little mopeds for about an hour and he

25:13

could navigate us back home without

25:15

needing sat nav or Google Maps. And if I

25:17

go 3 minutes down the street, I'm lost.

25:20

Mhm.

25:20

And I always wondered why that was. Is

25:21

it because And then even with names and

25:23

stuff, I would always He's my best

25:24

friend. He's He's one of my best friends

25:26

for for 7 8 years. We ran a business

25:28

together and he would remember every

25:30

name of every person

25:32

and I couldn't. I wouldn't. And so I'd

25:34

always turn to him and say, "What was

25:35

that person's name again? What's that

25:36

you know?"

25:37

And I always wondered why my memory He

25:39

seemed to have this incredible memory

25:40

and mine seems to be pretty rudimentary.

25:43

I would argue that um yeah, everybody

25:46

has parts of their memory that aren't as

25:49

good as they want, but also other forms

25:52

of memory that they're very good at. So,

25:54

I would guess, I've only just met you

25:56

today, that your memory for stories and

26:00

storytelling and story progress is

26:03

excellent because it has to be for the

26:05

job that you do. I bet you it's much

26:07

better than your friend that can

26:09

navigate back. Not everybody has a

26:11

perfect memory in all the different

26:12

dimensions and and it's like our

26:14

personality. Some people have a

26:16

wonderful sense of humor and others

26:18

don't. Um It is about how our brains are

26:21

wired, which is defined both by nature

26:23

and nurture, our genes and you know, if

26:26

I if I went to uh stand-up comedy class,

26:29

I would probably get funnier, but um uh

26:32

but there's probably a limit to my

26:33

funniness compared to other people.

26:35

So, there's different types of memory.

26:37

Yes.

26:38

In your book, you talk about there being

26:40

I think it's like three different types

26:41

of memory in total.

26:43

That are formed in the hippocampus.

26:44

Uh there's lots of different names for

26:46

forms of memory in the hippocampus. Um

26:49

but I like to describe it as The

26:51

hippocampus is critical for our memory

26:53

for facts and and events. Um also called

26:56

declarative memory or cognitive memory.

26:59

Uh another form of memory that's

27:00

dependent on a completely different

27:02

structure is motor memory, like the

27:04

memory that you uh use to learn how to

27:07

play tennis or pickleball or whatever

27:09

you're playing. And it's not

27:10

declarative. I can't declare how I do a

27:13

backhand in in in tennis, but it is in

27:16

your motor functions. And and this is

27:18

dependent on the striatum and a a

27:20

motor-related structure. And then

27:21

there's the prefrontal cortex dependent

27:23

on that working memory or scratchpad

27:26

memory, keeping things in mind. So um

27:29

you and I are both trying to remember

27:31

what we've just said so we can we can

27:33

link it to things that we might say in

27:34

the future.

27:35

Uh uh one of the things I found really

27:36

interesting, both as a marketer but also

27:38

as a podcaster and as someone that's

27:40

making a lot of

27:41

content and trying to get people's

27:43

attention, was as I was reading through

27:45

your work it became quite clear to me

27:46

that there's an a bit of an overlap

27:49

between memory and attention in in many

27:51

respects because you were talking about

27:52

these four things that make facts or

27:53

events memorable. And many of those

27:53

things are things that I think about as

27:53

a marketer when I'm trying to get

27:53

someone

27:54

that make facts or events memorable.

27:56

Yes.

27:56

And many of those things

27:58

are things that I think about as a

27:59

marketer when I'm trying to get someone

28:01

to, you know, engage with something,

28:03

click on something, buy something. What

28:05

are those four things?

28:06

Okay.

28:06

Can we go through them?

28:07

Absolutely. So I like to say there are

28:10

four things that make memory stick.

28:14

And this is after 25 or 30 years

28:16

studying the hippocampus and and how

28:18

memories work. Number one is obvious

28:20

repetition.

28:21

Okay.

28:21

You you remember things with repetition.

28:23

Number two, not as obvious, association.

28:27

The hippocampus is an associative

28:30

structure. It associates one thing with

28:32

the other. Uh for example, your name and

28:34

your face. So I'm you know, I've just

28:36

met you and I mean I I I will remember

28:38

your name and your face now, but it also

28:41

helps you remember things like who's

28:43

married to each other, associating the

28:44

husband with the wife. Uh have you heard

28:47

of the memory palace?

28:49

Uh yes.

28:50

Yes. So, this is a technique that has

28:52

been used for many, many

28:54

ages uh to help remember things. And it

28:57

is a strategy where you picture a

29:01

special location

29:03

that's very familiar to you, like your

29:04

childhood home. And when you need to

29:07

remember a list of items, you take an

29:10

imaginative walk through that very

29:12

familiar environment and place those

29:14

items in particular locations in the

29:18

environment. That is associating

29:21

something really familiar, your

29:22

childhood home, you know every corner of

29:24

it, with the new thing you need to

29:26

remember. And that works uh and has

29:29

worked for memory champions for many

29:31

years because the hippocampus associates

29:34

things together.

29:36

That's number two, association. Number

29:37

three is novelty. We remember novel

29:41

things. I've never been to this

29:43

particular studio ever before in my 26

29:46

years in New York and Brooklyn. So, this

29:48

is a novel thing and I remember I will

29:50

remember coming here uh to do this

29:52

podcast with you. Our brains, and this

29:55

is where it interacts with the attention

29:57

system. Our attention system focuses on

30:01

things that are novel. Why? Because it

30:02

could be dangerous. If I've seen it

30:05

things over and over and over again, I

30:07

don't notice them. They go into the

30:09

background. It's not going to hurt me

30:11

any, you know, it's not it's not going

30:13

to cause me any danger.

30:15

Cliché. That's why cliché doesn't work

30:16

in marketing.

30:17

Exactly. Yeah. And so, but something

30:20

novel, ooh, that really uh perks people

30:23

up. I use that in my teaching all the

30:25

time. Surprise students uh with uh an

30:29

element of what you want them to learn,

30:31

and they will remember it better.

30:33

But the fourth one, which is so

30:35

powerful, and we know it intuitively, we

30:38

understand this intuitively, is

30:40

emotional resonance makes things more

30:44

memorable.

30:45

We remember the happiest and the saddest

30:48

things in our lives because that

30:51

emotional resonance is solidifies those

30:54

memories. Where does that come from? It

30:56

comes from a structure called the

30:57

amygdala that sits right in front of the

30:59

hippocampus, right in the front of the

31:01

temporal lobe, right here. And the

31:03

hippocampus is right behind it. Amygdala

31:05

means almond. It's an almond-shaped

31:08

structure and it sits right in front of

31:11

um the kind of tube-shaped structure

31:12

that is the hippocampus behind it. And

31:15

the amygdala is kind of infusing uh the

31:18

hippocampus and kind of getting a giving

31:20

it a little jolt when it's emotionally

31:23

resonant, either really happy or really

31:26

sad.

31:28

You brought with you what you've told me

31:31

is a real human brain.

31:33

Yes, I did.

31:34

Now, I'm not sure if you're just winding

31:35

me up, but we're talking here about

31:37

novelty and surprise and

31:39

That's right.

31:40

things you'll never forget and emotional

31:41

resonance.

31:42

Correct.

31:42

And while you're saying that, I was

31:43

conscious that over in the corner of the

31:44

room it appears that there's a human

31:46

brain in a box. So, Jack is just

31:48

bringing the human brain in.

31:50

Yes.

31:51

I've never seen a human brain before.

31:53

You've never seen That's why I brought

31:54

you gloves so that you can hold it if

31:56

you like.

31:57

If you like.

31:59

Do you have permission

32:00

to If there is a human brain in this box

32:02

and you're not winding me up, did you

32:04

have to get permission from the

32:06

owner of that brain?

32:07

So, um this was

32:10

purchased uh lawfully um by my

32:14

department, the Center for Neural

32:15

Science at New York University. So, it

32:17

is lawfully ours to use as a teaching

32:21

tool.

32:22

And it does bring enormous novelty to

32:25

any situation that I go into and makes

32:28

people really think about their brain in

32:30

a new way, which is why I bring it.

32:32

What is in that box?

32:34

In this box is a real preserved human

32:38

brain named Betty.

32:41

Was the person

32:43

who used to own that brain called Betty?

32:46

No, we don't know the name of the

32:48

person. I named this brain Betty, so

32:51

Can you Can you tell if it's a man or a

32:52

woman?

32:52

No, I can't.

32:54

Huh. Man Men and women brains not

32:55

different at all?

32:56

They are, but in very, very subtle ways

32:59

that we wouldn't be able to tell just

33:00

looking at the the outside of the brain

33:02

like this.

33:03

Okay, I'm ready.

33:04

Are you ready?

33:05

I think so.

33:07

Okay. So, I'm going to open

33:11

the hat box.

33:13

No way is that a real

33:15

out

33:16

Are you joking? Is that really a brain?

33:18

It is

33:19

a real preserved human brain.

33:23

There it is.

33:25

Frontal lobe.

33:27

Frontal lobe.

33:28

Occipital lobe for vision.

33:31

Occipital lobe back there.

33:33

And in this brain, I don't know if you

33:35

can see it from over there, if I pull

33:37

apart

33:39

the two hemispheres, you can see how

33:40

deep

33:42

the the folds of the brain

33:45

the surface is folded in that deep into

33:49

the brain, which expands the surface

33:52

area of the outside of the cortex. The

33:54

rat cortex is flat. There's no folds.

33:59

Humans and elephants and dolphins have

34:03

lots of folds. They have much higher

34:06

capacity for computation because of the

34:09

folds that you see in this brain.

34:12

It's smaller than I was expecting.

34:13

Really? Half the people say it's

34:15

smaller, half the people say, "Wow,

34:16

that's that's enormous."

34:17

Interesting. Is that the the color of a

34:20

brain?

34:21

The color of the brain is darker than

34:23

the real brain if we opened up my head

34:26

right now, um, because of the

34:28

formaldehyde, the the preservative

34:30

chemical that this has been sitting in

34:32

for at least 26 years. This brain has

34:34

been in my department for

34:37

ever since I got here 26 years ago.

34:40

I feel like I probably should hold it.

34:42

I think you should hold it.

34:49

Oh my god.

34:51

It's wet.

34:52

Yes.

34:55

So, I mean that that has that defined

34:59

this person's whole life.

35:02

How they saw, felt, smelled,

35:05

heard, and thought about the world.

35:09

Just right there in your one hand, in

35:11

your right hand.

35:12

It's crazy to think that this little

35:14

thing is Oh, it's different underneath.

35:16

Yes.

35:18

It's crazy to think that this little

35:19

thing this little

35:22

That's the start of the spinal cord

35:23

right there that you're pointing at.

35:25

And this stuff at the underneath at the

35:27

back this

35:28

That is the cerebellum.

35:30

A brain structure critical for fine

35:32

motor movement. Um so, we wouldn't be

35:35

able to walk smoothly if you have damage

35:37

in your cerebellum.

35:39

Isn't it interesting that like

35:41

everything, as you say, everything this

35:43

person worried about, every thought,

35:45

every memory, every relationship,

35:48

all of their education, the school they

35:50

went to, the university, everything they

35:52

saw and remembered, and all of their

35:55

trauma,

35:56

Yep.

35:57

and their

35:58

anxiety, and maybe their depression,

36:02

everything they went through, even their

36:04

last days before they died, is like

36:06

captured in this little ball of like

36:09

tofu

36:10

Yep.

36:10

that sits in my hand. An entire human

36:12

being's existence.

36:14

It's true.

36:15

What they watched on TV, their favorite

36:16

movie, their favorite number, color,

36:18

everything is in this tiny little ball

36:20

of tofu.

36:23

It's true.

36:27

Oh gosh.

36:28

It is amazing and actually in real life

36:31

firm tofu is the consistency of of the

36:35

brain. I often bring in a

36:38

you know a block of of firm tofu

36:41

when I demo this for students in

36:43

addition to Betty.

36:45

Do you remember the first time you saw a

36:47

human brain?

36:48

I do.

36:49

Did it change how you think about your

36:50

own brain?

36:52

It changed my life because I was like I

36:57

want to study that. That is the coolest

36:59

thing that I've ever seen in my whole

37:02

life and I want to study that and I want

37:05

to be just like her and um

37:08

and so it it really like okay now I I

37:11

decided this is what I want to do.

37:14

And it was it was

37:17

it was life-changing.

37:19

I say that because we you know at the

37:20

start of this conversation we said that

37:21

most of us don't appreciate our brain. A

37:23

lot of people don't even realize it's

37:24

there.

37:25

Yeah.

37:25

The minute I had a brain scan one day

37:27

and that brain scan

37:29

really changed my life because seeing my

37:31

own brain for the first time

37:32

Yeah.

37:33

it was the push that I needed to start

37:35

caring more about how my decisions and

37:37

behaviors are impacting it. So let's

37:39

talk about how I can make that ball of

37:40

tofu in my head super healthy

37:42

Yeah.

37:43

Right.

37:43

You talked about exercise earlier on but

37:45

we didn't really dig dig into exactly

37:47

what you mean by exercise cuz exercise I

37:50

think is multifaceted in its definition.

37:52

What kind of exercise should I be doing

37:55

to make my ball of tofu in my head

37:58

great

37:59

Yeah.

37:59

optimal.

38:00

Mhm. Well, all the research shows that

38:03

the best kind of exercise that you can

38:05

do is anything that gives you aerobic

38:09

activity that is getting your heart rate

38:11

up. So that that goes for you know power

38:14

walking will get your heart rate up

38:16

soccer so many different things name

38:19

your activity. So many people want to

38:21

say oh

38:22

my favorite activity, will that work?"

38:23

And I always just say, "Is it Is your

38:25

heart rate up when you're doing it?" If

38:27

the answer is yes, then yeah, that that

38:29

works great. We know that that level of

38:31

aerobic activity is critical cuz that's

38:34

going to release that growth factor

38:36

maximally to get into your hippocampus

38:39

that will grow those new brain cells.

38:41

How much?

38:42

So, um I have an answer to that. So, um

38:46

we did two different experiments in my

38:48

lab. One in um low-fit people, people

38:51

that are really not exercising very much

38:53

at all, less than 30 minutes um

38:56

um in the last three three weeks you

38:58

you've moved your body. And um we asked

39:02

what could we see any behavioral

39:05

improvement in your memory function from

39:07

your hippocampus or your uh ability to

39:09

shift and focus attention if we ask you

39:12

to move your body in aerobic way for two

39:15

to three times a week. And we

39:17

collaborated with a spin class, so

39:19

clearly very aerobic. And what we found

39:22

was

39:23

in those people that did successfully do

39:26

two to three times a week of 45-minute

39:28

aerobic activity,

39:30

their mood got significantly better,

39:33

their memory function got better, and

39:36

their ability to shift and focus

39:37

attention got significantly better. So,

39:40

that gives a little bit of a guideline

39:42

for low-fit people, two to three times a

39:44

week can start to give you some of those

39:47

some of those cognitive changes. But,

39:50

you don't look low-fit. So, let me let

39:52

me answer the question you're about to

39:53

ask me. You're like, "What about me? I I

39:55

exercise pretty regularly." And um how

39:58

much how much do I need? So, to answer

40:01

that question, we went to another spin

40:03

studio, and we said, "Look, we're going

40:04

to give you free classes. You could

40:07

exercise as much as you want in this in

40:09

this um

40:10

at this studio, and uh um go up to seven

40:14

times a week." And the control was just

40:17

stay the same. You know, you they were

40:18

they were working out twice a week at at

40:20

the studio.

40:21

Control was the other group that were

40:22

you testing them against?

40:23

Yes, exactly.

40:25

And so what we found was

40:28

basically every drop of sweat counted.

40:31

The more you exercise, the more change

40:34

in your brain we noted. Both your

40:36

hippocampal function, prefrontal cortex

40:37

function, and mood.

40:40

If you you you were already getting

40:41

benefit, you know, you're already going

40:43

twice a week. But the more you did, the

40:46

more brain changes you got. So, that

40:49

that doesn't give the formula that I

40:51

would like, but we were heading in that

40:53

direction, which is part of one of the

40:55

questions that I want to answer. But I

40:57

love to leave people with the idea that

41:00

every drop of sweat counts for building

41:03

your brain into the big fat fluffy brain

41:05

that you really want.

41:08

And then in the real world,

41:10

again making it super um

41:12

real for people.

41:13

Yeah.

41:14

How how does that change how I show up?

41:16

Yeah.

41:17

If you allow it to, should have a

41:20

beautiful effect on your mindset.

41:22

Um that your mindset around um

41:27

how often should I take wake up

41:30

30 minutes early and do that walk before

41:33

I start my day or accept the the

41:36

invitation to go walk the dog with with

41:39

a neighbor. It's not an obligation. It

41:42

is something that you're doing for

41:44

yourself. It is going to have direct

41:46

benefits on that ball of tofu as you

41:48

call it in your head. It's going to make

41:51

it work better. And and I mean, I think

41:54

the most immediate thing that I benefit

41:56

from every single day is the mood boost

41:59

that you get from that serotonin,

42:01

dopamine, norepinephrine that gets

42:02

released every time you move your body.

42:04

I always think that cuz obviously I do a

42:05

little podcasting and it's I'm super

42:07

reliant on my brain being attached to my

42:09

mouth and sometimes I notice that it's

42:11

not. You know what I mean? Like

42:12

sometimes I'm not articulate, I can't

42:13

get my thoughts together, whatever.

42:14

Yes. And I always try I've tried to

42:16

figure out the correlation between what

42:17

I did that day when I have a good day

42:19

versus a bad day. And I've from from

42:22

your And also I speak on stage

42:23

sometimes, so I've often asked myself

42:25

cuz I saw Tony Robbins, the speaker, one

42:28

day on a trampoline before he goes up on

42:30

stage. I asked myself, okay, should I be

42:33

doing a workout in my green room before

42:35

I go up on stage for a big talk or

42:37

presentation?

42:38

You think I should?

42:38

Oh yeah, absolutely.

42:40

What's the basis of that in science and

42:41

neuroscience?

42:42

Uh it's the basis is that immediate So

42:45

there's three key effects that we know

42:47

happen every time you move your body.

42:49

First one is mood, you're going to get

42:51

your dopamine, your serotonin up. Um

42:53

second is focus and attention. So So a

42:57

single workout isn't going to make more

42:59

synapses in your prefrontal cortex, but

43:01

the prefrontal cortex uses dopamine. And

43:04

so um it's clear that even a single

43:07

workout can make your prefrontal cortex

43:09

work better in terms of focus,

43:10

attention. Also very important anytime

43:12

you're speaking. And the third is

43:14

reaction time. Your reaction time it you

43:16

know, motor your your your working your

43:18

motor cortex when you move your body and

43:21

your response and reaction time is

43:24

significantly shorter after a even a

43:27

single workout compared to if you just

43:29

don't work out and sit sit um alone. So

43:33

great great things to do. A great thing

43:35

to do before you you stand up and speak.

43:37

What about

43:39

coffee?

43:42

I I I'm trying to figure out if coffee

43:44

is good for my brain, bad for my brain.

43:46

I've had a couple of mixed messages

43:48

around

43:49

the impact it might be having.

43:51

Yeah.

43:52

You know, caffeine is a stimulant and uh

43:55

people respond to that kind of stimulant

43:57

uh in different ways. Overstimulation

44:00

with caffeine is is not good for your

44:02

your ability to put words together. You

44:05

know, this is where I turn to uh

44:08

a main theme in in my book Healthy Brain

44:11

Happy Life with this which is

44:12

self-experimentation.

44:14

For you, how what can you titrate your

44:18

coffee to see what level of coffee is

44:21

best for whatever your podcast or you're

44:24

giving a talk. The other thing that can

44:26

work similarly to coffee that that I've

44:30

started and that I do every morning is

44:33

hot cold contrast showers because that

44:36

cold that you

44:38

shower on yourself after the heat

44:41

stimulates adrenaline in you. A natural

44:44

adrenaline.

44:45

It wakes you up and okay, it was painful

44:48

the first kind of few times I tried it,

44:51

but then you get addicted to it and I

44:53

have forgotten to do it and gotten back

44:56

in the shower just to douse myself with

44:59

cold water because I feel better when I

45:02

do that for for you know, first thing in

45:04

the morning. So, lots of different

45:06

things that one can explore with.

45:09

Okay, on the other side of the coin

45:10

then, what are some of the central

45:12

behaviors that people do that destroy

45:14

their brain?

45:17

Well, sedentary behavior is one of them.

45:21

Um, not getting enough sleep

45:23

is critical. We haven't talked about

45:25

sleep yet. Sleep is so important for

45:28

normal functioning of the brain. I like

45:31

to scare my students by saying that um,

45:34

you know, in torture situations, if you

45:36

deprive a person of sleep for too long,

45:39

they literally die. They they they die.

45:41

You cannot function if you are deprived

45:44

of sleep for too many hours in a row.

45:47

It's that critical. Yet, we don't we we

45:49

happily you know, watch too much Netflix

45:51

at night and and and and get only 5

45:53

hours of sleep when we could have had

45:55

eight. So, what's happening exactly? Why

45:58

is it so important? Well, there's

46:01

there's so many different things. I'm

46:02

going to I'm going to say two. One is

46:04

that we know that in regular

46:08

um healthy sleep there is activity in

46:11

the hippocampus that helps you

46:13

strengthen the memories that you have

46:15

formed in that previous day. It's called

46:17

consolidation and it's so important. If

46:20

you shorten that, if you don't get

46:21

enough, you are not consolidating your

46:24

normal everyday memories. And second, it

46:27

is the time during sleep when all the

46:31

metabolites, all that garbage that your

46:33

brain is producing because all

46:35

biological cells produce garbage, it

46:38

gets kind of cleaned up through the

46:41

cerebral spinal fluid that that is

46:42

flowing through your brain. And if you

46:45

do not get enough sleep, you build up

46:47

garbage metabolites in your brain. It's

46:49

like you have a gunky brain. And do you

46:51

feel like I feel like I have gunk in my

46:53

brain when I don't sleep enough. That is

46:55

exactly what is what is happening.

46:58

Well, when you think about things that

46:59

we consume, you know, like food and

47:02

drink and alcohol and all these kinds of

47:04

things. Is there is there anything that

47:06

if I'm trying to have an optimal brain,

47:07

I should be

47:08

Yeah.

47:08

having or not having?

47:10

Yeah. Well, so um

47:12

I think the most evidence is around the

47:16

benefit of the Mediterranean diet, which

47:20

is basically all healthy

47:23

kind of organ not organic, but

47:25

non-processed is the word I was trying

47:27

to think of things to eat that are very,

47:30

very colorful.

47:31

There is so much evidence about how good

47:34

that is generally for the brain. That

47:37

that is my go-to. Like what what should

47:40

I eat? Well, is it on the Mediterranean

47:42

diet? If it is, then go ahead. If it's

47:44

too processed,

47:45

only do it. Just a little bit.

47:48

Is it true that if we have less friends,

47:50

if we have less strong relationships, if

47:52

we're lonely, then our brain will shrink

47:55

and is more prone to dementia and

47:58

Alzheimer's and things like that.

47:59

Yes, we are social creatures and um

48:03

there are uh really powerful studies

48:06

that have shown the correlation between

48:08

the number of social connections that we

48:10

have, including just saying hello to the

48:12

barista at Starbucks. It's not a close

48:16

friendship that you develop over 30

48:18

years. It's It's just how many people

48:20

you interact with and greet and

48:22

longevity. The more people you are

48:25

regularly interacting with, the longer

48:28

you are living. Overall longevity. But

48:31

if you go into brain health, absolutely

48:33

it's also very very healthy for you. It

48:36

also brings happiness. So uh friend and

48:40

colleague of mine um Robert Waldinger uh

48:42

studied um what makes people happy. The

48:45

study started in the '20s, the 1920s at

48:48

in in Harvard. And after all of those

48:51

many many many decades, the answer is

48:55

what brings happiness is the strength of

48:57

your social connections. So, it makes

48:59

you happier, it makes you live longer,

49:01

and and uh yes, loneliness on the on the

49:04

um flip side

49:05

causes stress, uh long-term stress that

49:08

that damages the brain and uh yeah, in

49:11

the long term can can make it smaller

49:13

and uh less healthy.

49:15

Do you have any brain routines? Like any

49:17

like a morning routine for your brain?

49:19

Absolutely. So, every morning I like to

49:21

wake up and I do a um

49:24

tea meditation, which is a meditation

49:27

over the brewing and drinking of tea.

49:29

And this is after many years of yo-yo

49:31

meditating. I knew meditation was good,

49:34

but I just couldn't really get into it

49:36

and um

49:37

I was introduced to this form of

49:39

meditation um from uh by a monk who who

49:43

invited me to tea and and just did this

49:46

silent meditation outside in a beautiful

49:49

location. And the ritual and the um

49:53

um the sequence of brewing, drinking,

49:56

seeping,

49:58

re- starting over again kind of kept me

50:01

in kept me in the flow. And so I start

50:03

with about a 45-minute tea meditation.

50:06

Then I do about a 30-minute workout. I

50:08

try and do cardio strength. Sometimes I

50:10

do yoga. Sometimes I just do mobility.

50:13

And then I have breakfast and then I go

50:15

to work.

50:16

Oh, and then I I do that heart hot cold

50:18

contrast shower is also something very

50:21

helpful for my brain health because it

50:23

it really does in me that adrenaline

50:26

boost that I get just energizes me and I

50:28

love that feeling at the beginning of

50:30

the day.

50:31

Just going back to that question cuz I

50:31

want to close off on it as well. The the

50:33

idea of what would I have to do to

50:34

destroy my brain. So, no sleep.

50:37

Yeah.

50:37

I'm going to be sedentary.

50:39

Yeah.

50:39

I'm going to have no friends.

50:41

Yeah.

50:42

And smoking?

50:44

Smoking is very bad for your health and

50:46

and your brain.

50:47

Okay.

50:48

Alcohol?

50:50

Alcohol, I mean, yes, long-term alcohol

50:52

can cause significant and named brain

50:56

diseases.

50:58

Moderation even moderation now as

51:00

studies have shown it is not very good.

51:01

And the reason why it's not good is that

51:04

alcohol disrupts your sleep. Even though

51:07

people drink it to to go to sleep

51:09

faster, the sleep is much more

51:12

superficial and is not deep and it's not

51:14

the healthy sleep. So, that is not good

51:18

overall for your for the for sleep depth

51:21

and and health and therefore brain

51:24

health.

51:25

I'm going to eat a processed diet to

51:27

hurt my brain.

51:28

And I'm not going to have a lifestyle

51:30

that is

51:32

novel. Because we talked about learning.

51:34

Right.

51:34

Yes.

51:35

not going to learn anything new.

51:36

All of these things should shrink that

51:38

little

51:40

You're not going to be mindful also.

51:42

Does mind Is that Is that evidence that

51:44

being mindful, which is like meditation

51:46

and being in the moment helps the brain.

51:48

It does. There's beautiful studies

51:51

showing brain plasticity

51:54

in the areas that are important for

51:57

focused attention. Meditation, the

51:59

practice of meditation is basically a

52:01

practice of

52:02

enriching the function of your

52:04

prefrontal cortex. So you can focus on

52:06

that object, either the breath or or

52:10

loving kindness is is a form of

52:12

meditation. So yes, there there's been

52:14

studies that brain changes occur in

52:18

long-term meditators that are that are

52:20

absolutely beneficial.

52:21

What if I'm on social media all the

52:22

time?

52:23

Because isn't that good for me because

52:25

I'm going to be seeing lots of new

52:26

things all the time and I'll be learning

52:27

lots of new things. So isn't if I sat on

52:29

a on a screen for 7 hours a day

52:33

is that good for my brain, social media?

52:35

Does that take you away from real people

52:37

and interacting with real people?

52:39

Yes.

52:40

Okay. Then then it's modulated by that.

52:43

There

52:43

the same thing?

52:44

There's a difference and I think your

52:45

brain knows it and

52:48

look, there's there's enormous amounts

52:50

of evidence showing that the increase in

52:53

use of social media

52:56

especially in young kids correlate with

52:59

huge increases in depression and anxiety

53:02

levels particularly in young girls. So

53:04

when

53:06

when kids started getting the

53:07

smartphones and started to spend more

53:10

and more 7 hours a day on social media,

53:13

that's when the anxiety and depression

53:15

went up. That's for young kids. I use

53:18

social media as well as a tool for

53:20

business. That is a little bit

53:22

different. I'm not 13 years old and

53:24

you're not 13 years old. So so you know,

53:26

there there's some warnings I think that

53:28

need to go into into that. But but let

53:31

me let me be clear. No, it's not the

53:33

same. Social media is not the same as

53:36

social interaction face-to-face with

53:39

people.

53:39

Are Are are you concerned about what

53:41

social media is doing to our brains?

53:43

Yes.

53:43

Cuz you know we I hear we hear those

53:45

stats around, you know, young young

53:46

girls are struggling most with social

53:48

media and we think to ourselves, well,

53:49

that's because there's a lot of like

53:50

comparison and all these kinds of things

53:53

and there's a lot of like toxic

53:54

messaging and such, but

53:57

if we think about the physiological

53:58

consequences of social media, what it's

54:00

actually doing to our brains at a

54:02

chemical level.

54:03

Yeah.

54:04

What what would you as a neuroscientist

54:06

guess is like is the physiological harm

54:09

to the brain? Not the sort of psycholo-

54:10

I'm thinking about like not the

54:11

psychological like, okay, oh my god,

54:12

she's more this than me, but like the

54:15

physiological harm.

54:16

But the psychological harm causes

54:19

stress. Stress releases stress hormone

54:22

that goes into the brain that at too

54:24

high and too constant a level can start

54:27

to first damage connections and then

54:29

kill cells. So it's it's intertwined

54:33

um there and that that is part of of

54:35

what is happening. Um you can't, you

54:38

know, pull one

54:39

one away from the other.

54:41

Cuz you know, we're social media is

54:43

designed to kind of It's like pulling

54:44

the slot machine handle. I pull down on

54:46

the feed and I get ping, oh look,

54:47

there's a nice picture and oh ping,

54:49

there's notifications and comments, etc.

54:51

It's that con- You know, I think about

54:53

the constant

54:54

They they say there's constant dopamine

54:56

hit.

54:56

Yeah.

54:57

to it. Is it a dopamine hit? Is that's

54:58

what's happening when we're being

54:59

stimulated by social media or a slot

55:01

machine?

55:01

Yes.

55:02

And is there Is there any harm in just a

55:04

constant dopamine hit all day every day?

55:06

Well, I would not I'm going to answer

55:08

that question by saying I would not want

55:11

to be addicted to gambling.

55:14

That gambling is addictive. It It's hard

55:16

to get away. You You You lose all these

55:19

other things that we just decided were

55:20

all good for you, including sleep,

55:22

including social connections, um

55:25

including exercise, and I think that's

55:27

part of what social media is doing for

55:29

our young kids is not good that they're

55:30

not

55:32

joining teams outside to be social and

55:35

interactive in uh in that

55:38

kind of now it seems like an

55:40

old-fashioned way, but it's very very

55:42

powerful way for development um and

55:45

brain health.

55:46

I think I'm addicted to my phone.

55:47

Mhm.

55:48

And I I often ask myself, is that is

55:51

that a problem? And from what you've

55:52

said, it sounds like the problem is what

55:54

I sacrifice

55:55

Yeah.

55:56

through that like addiction to that

55:57

device.

55:58

Yes.

55:58

Is that that the issue? The issue is I

56:00

sacrifice social connections, maybe

56:02

movement.

56:03

Yeah.

56:04

You know. Although I do work out every

56:05

day.

56:06

But the brain is smart enough to know

56:08

that there's no substitute for real

56:10

human connections.

56:11

Absolutely.

56:13

Absolutely.

56:14

And that's going to make me what? I'm

56:16

trying to I I need you to help me

56:20

Yeah.

56:20

scare me out of this

56:22

phone addiction that I think I have, but

56:23

I know many other people have as well.

56:26

So, that is going to limit your

56:29

potential for brain growth for for brain

56:32

plasticity. It is going to limit your

56:36

possibility for for, you know,

56:40

not to be dramatic, but joy in in your

56:42

life. There's different kinds of joy

56:43

that you have in in real

56:46

person-to-person social interactions

56:49

that it feels pretty good on social

56:51

media if you get lots of likes and, you

56:53

know, um but it's not the same. And um

56:57

I would I would say that to scare

57:00

yourself out you're going to have to

57:03

bite the bullet and do a 2-week phone

57:07

detox.

57:08

What would that do to you? How would you

57:10

feel?

57:12

I just could never imagine such a thing.

57:14

Well.

57:15

Which is a real shame, isn't it, really?

57:16

Cuz I just think about like my ancestors

57:18

and my parents, they must

57:19

they must think I'm so strange, but it's

57:21

just the just the way that like when my

57:23

phone dies, I'm like there's like

57:26

I'm like nervously waiting for it to

57:27

come back on. I'm like staring at it

57:29

like, "Oh my god, like Like, am I going

57:30

to do with myself?" Like,

57:32

uh

57:33

and I remember those studies they did on

57:34

people where they gave them the choice

57:37

of either sitting alone with their own

57:39

thoughts or giving themselves an

57:40

electric shock, and a huge amount of

57:42

people in that study actually would

57:43

rather give themselves an electric shock

57:46

than just sit alone with their thoughts

57:47

because it's some kind of stimulation.

57:49

That's kind of how I think I am now.

57:51

Like, I don't know what I'd do without

57:52

my phone. It's really sad. I know

57:54

there's people listening to me now that

57:55

think I'm an absolute like I'm really

57:57

sad, but it's just the naked It's the

57:58

truth, you know? And

58:01

um I do wonder what it's doing to my

58:02

brain, but I think you're right. I think

58:03

it's actually what it's doing to my like

58:05

my life.

58:06

Yeah.

58:07

The joy, the connections, the

58:09

being being there to experience things,

58:11

and um

58:12

I mean, that point that you made is a

58:15

very profound one.

58:17

Um the the not wanting to be alone with

58:21

your thoughts

58:22

is the core of meditation. Can you be

58:26

alone with your thoughts and focus on

58:28

something

58:30

something organic, usually the breath,

58:32

but also a thought like loving kindness.

58:35

Um that is a very powerful practice to

58:38

do, and it and it's hard. I find it

58:39

hard, too. Um

58:41

and I actually I notice I find it harder

58:43

when I'm

58:45

when I'm using social media and when I'm

58:47

using my phone more. Um

58:50

but I feel most creative

58:52

and most imaginative when I do practice

58:56

that. That is, being alone with my

58:58

thoughts. What comes into mind? Um how

59:02

how does my own imagination work, which

59:05

is very much dependent on the

59:07

hippocampus as well. It's putting

59:08

together all these things in your memory

59:11

in new and interesting ways that are

59:13

unique for you or unique for me. And it

59:16

doesn't work the same if you are

59:18

stimulating your brain with social media

59:20

all the time.

59:21

You um I mean, you wrote a book that

59:23

kind of speaks to some what we're

59:23

talking about here. You wrote a book

59:24

about anxiety.

59:25

Yes, I did.

59:26

In 2021. Yeah, I think the the US

59:29

version's called Good Anxiety, isn't it?

59:31

Slightly different title in the US in

59:32

the UK.

59:33

Yeah.

59:34

Why did you write a book about anxiety?

59:36

I wrote a book about anxiety because I

59:38

started to notice my students

59:42

getting much more anxious than they ever

59:43

used to be.

59:44

And this was before the pandemic. I

59:47

mean, I I I had the idea to write this

59:49

book in

59:51

2018, 2019.

59:53

And

59:55

so first I noticed it in the students.

59:56

They were getting so stressed out before

59:58

finals. They never did that before. So

60:00

so many accommodations they were asking

60:02

for.

60:03

And I'm like, "What's going on here?"

60:05

But then I realized it wasn't just them.

60:07

Like I'm getting more anxious as well.

60:09

My friends are more anxious. And I

60:11

really wanted to dive into that. I

60:13

didn't want to be anxious in that way.

60:16

Uh cuz part of me was like, "Oh, I'm

60:18

just a New Yorker. I'm I'm just anxious

60:19

all the time, right?" Cuz that's what

60:20

New Yorkers are. No,

60:23

this has changed. And we forget that

60:25

before the pandemic, there was there was

60:27

still global warming warming. There was

60:29

still political issues that that lots of

60:30

people, including me and all of my

60:32

students, were worried about.

60:35

And that was the impetus for for trying

60:38

to dive in and ask, "Well,

60:40

I made my life happier with exercise.

60:43

What What is the approach when it's

60:45

anxiety? And not clinical anxiety. I did

60:48

not have clinical anxiety. And the vast

60:49

majority of my students didn't have

60:51

clinical anxiety. They had what I called

60:53

everyday anxiety. Just worried about the

60:56

things that are going on in the world.

60:58

And there were just more things to be

60:59

worried about."

61:00

Is that normal? Is that human?

61:02

That is human, absolutely.

61:03

But is it human in the

61:06

in is the quantity in which we

61:07

experience it human?

61:10

Uh I think it is. I mean

61:12

Cuz I think about my ancestors. I go,

61:13

they they probably I don't know. I

61:15

always imagine my ancestors kind of I

61:16

don't know, just chilling.

61:18

Do you know like I've got

61:18

But they didn't have they didn't have

61:20

global warming where the ocean is about

61:22

to, you know, get sucked up in plastic

61:25

and and the the ozone is going to come

61:27

come down. No worries like that at all.

61:30

But but the everyday anxiety for me is

61:32

like emails.

61:34

And WhatsApp.

61:35

Well, by everyday anxiety I mean the

61:38

anxiety that people are feeling today

61:41

that is not at the clinical level. So,

61:43

all the things that we just men-

61:45

mentioned, global warming and wars in

61:47

multiple places in the world, all of

61:49

that contributes to the higher level of

61:52

anxiety. And your ancestors and mine

61:55

went through two world wars.

61:57

But and that was anxiety provoking, no

61:59

question about it. But they weren't also

62:02

all the other things that were um

62:05

you know, contributing to it including

62:07

the higher than, you know, extremely

62:10

high anxiety and suicide levels of our

62:13

young people

62:14

that are, you know, that strongly linked

62:17

to social media. So, that's that's

62:19

another element.

62:20

What did you find then when you started

62:21

uncovering and trying to go on this

62:23

search of figuring out, you know, the

62:25

the nature of anxiety and what we can do

62:27

about it? Did you first find that your

62:29

writing your hypothesis that it is

62:31

increasing?

62:32

Yeah.

62:32

Yeah, that was

62:34

Do you know how much?

62:36

Um you know, it it shifted over the time

62:38

that I wrote and published the book

62:40

because I started in 2018 and then it

62:42

was published in the middle of the

62:44

pandemic in 2021 where anxiety levels

62:47

went up approximately 20%

62:50

worldwide.

62:51

So, um

62:53

but the social media anxiety, um that is

62:56

going up in girls even more than 20%. Um

62:59

that's kind of in parallel. So, I I I

63:01

actually don't know how to um integrate

63:03

those two levels, but they're both going

63:06

in the same direction.

63:06

Why are women, young women, becoming

63:11

more anxious and suicidality amongst

63:13

that age group is

63:15

rapidly increased.

63:17

You know, I think that um it's it's that

63:21

comparison that that is so easy to do

63:24

and I see it in my own work at the

63:27

university that

63:29

when I was going to college, I had no

63:30

idea what rank I was in in number in the

63:34

application, but they could see that

63:36

immediately. They know exactly what

63:38

number they are in each and every class

63:39

they take in their whole high school

63:41

class in the in their application to to

63:45

the five schools that they applied to or

63:47

10 or 15 now that they're applying to.

63:50

That gives a much higher level of stress

63:53

when you know those numbers immediately.

63:56

Um that we never had. So so there are

63:58

stresses like that that that um they're

64:01

they're experiencing.

64:02

More information.

64:03

Yeah.

64:03

More

64:05

It's funny cuz more social connection,

64:07

but it's I want to say social

64:08

connection, I don't mean real world

64:10

social connection. I mean more followers

64:11

and likes and

64:13

Yes.

64:13

that can message me and tell me

64:14

something and DM me or comment on my

64:16

thing.

64:17

Right.

64:17

More noise.

64:18

Yeah.

64:19

The volume has increased, which is seems

64:20

to be driving more anxiety. Where do we

64:22

experience anxiety? Where from a

64:24

physiological standpoint, where is

64:26

anxiety? Cuz it feels like it's in your

64:28

chest.

64:28

Yeah.

64:29

So anxiety is kind of a full body

64:32

experience and um anxiety is um

64:37

strongly linked with the stress

64:39

response. So um an anxiety-provoking

64:42

situation, you you um

64:45

meet somebody that you uh you know, had

64:47

a big fight with before. Oh, I'm

64:49

anxious. I might have to speak to that

64:51

person before. Uh that

64:54

launches that launches the stress

64:56

response

64:58

um that is um dependent on what's called

65:01

the sympathetic nervous system. And so

65:03

this is where it becomes full body. So

65:05

what happens when your fight or flight

65:08

system is activated? Your heart rate

65:09

goes up. Your respiration goes up. Your

65:12

um irises get get bigger so you can see

65:14

everything and look out for that that

65:16

annoying person that you're worried

65:17

about. And blood is shunted from your

65:20

digestion and reproduc- reproductive

65:22

organs towards your muscles so you can

65:24

fight or run away. That's what all of

65:26

our ancestors evolved to protect us from

65:30

not

65:31

not the social media post, but

65:34

the lion or the tiger that could come

65:36

and attack us. So it made sense for that

65:39

kind of stressor or that kind of threat.

65:42

Unfortunately, our bodies do the same

65:45

exact thing when the nasty DM comes in

65:49

from somebody I wasn't sure who it is,

65:50

but they're saying something really bad

65:52

about something I care about a lot. And

65:54

we get this stress response, we get

65:56

anxious because of that. And somebody

65:59

asked me, "Does that mean our brain is

66:00

not very smart?" And the answer is our

66:03

our our stress and our threat system is

66:05

not very smart. It isn't differentiating

66:07

between the lion that could physically

66:09

kill us and the DM that might wound our

66:13

pride,

66:14

but but will not kill us. But it causes

66:17

the same kind of

66:19

stress response and anxiety response.

66:22

What do I do about that?

66:23

You have to learn how to turn the volume

66:26

of your own anxiety down. And part of

66:29

that is I'm not saying you have to not

66:31

look at your DMs and not look at or not

66:33

look at social social media. There's

66:35

lots of ways to turn your anxiety down.

66:38

We've already talked about some of those

66:41

approaches. Exercise immediately

66:44

decreases anxiety and depression levels.

66:46

And there, you don't even have to get

66:48

aerobic. 10 minutes of walking can

66:51

significantly decrease your anxiety and

66:53

depression levels. That is a powerful

66:55

tool that everybody can use right right

66:58

here right now.

66:59

Breath meditation. Did you know that

67:02

breath meditation, that is deep

67:04

breathing,

67:05

um

67:06

is the oldest form of meditation. Why?

67:10

Because equal and opposite to that fight

67:12

or flight response that everybody seems

67:14

to know about is the rest and digest

67:17

part of your nervous system called the

67:19

parasympathetic nervous system that

67:21

calms you down. It slows your heart rate

67:24

down, slows your respiration rate down,

67:26

and shuts blood from your muscles

67:28

towards your digestion and reproductive

67:30

organs so that you can do those weekend

67:33

rest and digest kinds of things.

67:35

Well,

67:37

everybody should be asking, "Well, do I

67:39

have that system?" Yes, everybody has

67:41

that system. Everybody has a

67:42

parasympathetic nervous system. How do I

67:44

activate that? The best and most

67:46

effective way that you can activate that

67:48

right now is take three deep breaths

67:51

because that's the only thing you have

67:53

conscious control over that can launch

67:56

all the rest of that parasympathetic

67:58

activity slowing your heart rate. I

67:59

can't slow my heart rate by thinking

68:01

about it. Can I take three deep, slow

68:04

breaths right now? Absolutely. And monks

68:07

hundreds, if not thousands, of years ago

68:09

realized that. That is the thing that I

68:11

can do immediately to slow my slow my

68:15

stress response down. It's very, very

68:17

powerful.

68:18

Sadness.

68:19

Sadness.

68:21

Sadness is um

68:23

can be linked with anxiety and um

68:28

you know, sadness like anxiety is

68:30

something that people

68:31

I think would like to kick out of their

68:33

lives and just never have any more

68:37

at all. If I could get rid of sadness

68:39

and anxiety, I would be the happiest

68:40

person alive.

68:42

But would you?

68:44

Because my argument in good anxiety, my

68:46

book Good Anxiety, is that

68:49

these prickly emotions, these difficult

68:51

emotions, like anxiety, like sadness,

68:56

are really, really valuable because

68:57

they're they're focusing us on things

69:00

that we should be paying attention to.

69:02

Specifically, anxiety. It is a warning

69:04

system. Oh, there's that person. Oh, you

69:06

didn't have a good interaction. You you

69:08

need to pay attention. Now, should it

69:11

throw you into a an anxiety attack?

69:14

Perhaps not. Use some of these

69:15

techniques. Um like like deep breathing

69:18

and and going for a walk. But it is a

69:20

warning system. And

69:23

why is this valuable? Here's why it's

69:25

valuable. It's valuable because when you

69:28

know what

69:30

you are worried about, your fears that

69:33

your anxiety focuses you on, it actually

69:36

tells you about what you hold most dear

69:40

in your life. And that is something that

69:42

we should all

69:44

really want to know. So, if you're a

69:46

people pleaser,

69:47

um you are doing lots of things to maybe

69:50

too many things to please people, but

69:53

that means that you care about

69:57

personal interaction. And I start with

69:58

this one because I'm a people pleaser.

70:00

And I realized that people-pleasing

70:03

response and the anxiety that it does

70:06

evoke is reminding me that what's very

70:10

very valuable to me is that interaction

70:12

with people. I care about that. That's a

70:15

beautiful thing. I value that in my

70:18

life, in my personality.

70:21

I'm going to let you in on a little

70:22

secret. What is in The Diary of a CEO

70:25

cup? This cup that sits in front of me

70:27

when I interview these people, sometimes

70:29

for 3 hours, and sometimes three people

70:31

a day. And the answer is this, Huel. I

70:33

invested in the company on Dragon's Den,

70:36

and since then they've gone from an idea

70:38

to the fastest-growing energy drink in

70:41

the UK. It is a matcha energy drink, and

70:44

it is absolutely delicious. But that's

70:46

not why I choose to drink it on this

70:47

podcast. The reason I choose to drink it

70:49

is because it gives me what I call

70:51

all-day energy. I don't get the same

70:53

crashes that I used to get with other

70:54

energy drinks. If you're in the middle

70:56

of a conversation, or you're in the

70:57

middle of a talk on stage, or in the

70:58

board room, the last thing you want to

71:00

do is have a crash. You don't want

71:02

jitters, and you need focus. And that is

71:05

why they now sponsor this podcast. Not

71:07

only is it delicious, but it gives me a

71:09

significant competitive advantage. If

71:11

you haven't tried it, go down to a

71:12

Tesco, go to a Waitrose, or go online

71:15

and use the code diary10 at checkout,

71:18

and you'll get 10% off. And when you do

71:19

try it, let me know how you get on.

71:22

Do you think we could see love in the

71:24

brain? Can you see if someone's in love

71:25

in the brain?

71:26

If we scan the brain of someone that's

71:28

in love when they're interacting with

71:29

their partner, could we see that?

71:31

Um yes, in fact, they have scanned

71:33

people who are in the throws of of uh um

71:37

romantic love, and people that are in um

71:41

you know, many years into a loving

71:44

relationship.

71:45

And there are uh lots of reward areas

71:49

that get activated when you're scanning

71:50

the brain um of somebody that that, you

71:53

know, is in the throws of deep romantic

71:55

love, that is in the first few weeks.

71:57

You can't get enough of the person,

71:58

you're with them all the time, you can't

71:59

stop thinking about them. A lot of the

72:02

reward areas are are activated. Uh a lot

72:05

of the social interaction areas,

72:08

including the insula, uh a part of the

72:10

brain right in the side here, just just

72:13

uh

72:13

in the uh area near the ear, deep into

72:16

the cortex, get gets activated.

72:19

Doesn't that mean then that if we don't

72:21

fall in love, if we don't have those

72:22

feelings,

72:23

that that part of our brain might

72:24

shrink? Because if, you know, they say

72:26

often things like

72:28

you you use it or you lose it. They say

72:30

neurons that fire together, wire

72:32

together. If I'm not in love, if I'm not

72:33

if I don't have those social

72:34

connections, will the love part of my

72:36

brain get smaller?

72:37

And would that make it more difficult to

72:39

love in the future?

72:41

That's a great question. I think that um

72:44

that study has not been done, but

72:46

absolutely, if uh

72:48

uh if you don't use that part of the

72:50

brain, um you will not, you know, gain

72:53

the function. And so, yeah, not not

72:56

using your love part of your brain is is

72:58

not a nothing that I would ever

73:00

recommend.

73:01

Some people, I guess, don't have a

73:02

choice. Well,

73:04

I guess they have a

73:07

choice

73:08

in the sense that they can do things.

73:09

They have optionality, but

73:12

for whatever reason, some people don't

73:13

find love. It's just an interesting

73:14

observation because in all other parts

73:15

of the brain, you have to like

73:16

Do you mean romantic love?

73:18

Romantic love, yeah.

73:19

But but you know, there's all sorts of

73:21

different kinds of love. Deep

73:23

friendship, um, it's actually what I was

73:26

going to say is that, um,

73:28

they tried to look at the difference

73:30

between romantic love and maternal love

73:34

or paternal love. And it turns out that

73:37

long-term relationships, like

73:39

romantic relationships of marriages that

73:41

last for many years, start out, of

73:43

course, in this romantic phase. But it

73:46

turns into more of a maternal, paternal,

73:51

um, pattern

73:53

when you go farther and farther along.

73:56

That that is a win. That is not

73:58

something wrong with your brain. Um, I

74:00

think love does evolve over time, and

74:03

there's many different kinds of love

74:05

beyond the romantic Hollywood

74:09

you know, uh, and Disney kind of, uh,

74:11

uh, form of love.

74:13

So, you can see the honeymoon phase in

74:14

the brain.

74:15

Yes.

74:15

And then you can see the more

74:17

mature love, I guess.

74:18

Yes.

74:19

In the brain. Interesting.

74:21

Oh, the I guess the the opposite of love

74:25

I guess might be hate, but I think when

74:28

another sort of thing that people might

74:30

think of is

74:31

the opposite of love would be rejection

74:33

or heartbreak. And through all of our

74:35

lives, we encounter heartbreak in many

74:37

forms. We encounter romantic heartbreak,

74:39

but also other forms of heartbreak. As I

74:41

read through your story, I I I I could

74:43

see moments in your story where

74:45

you encountered various types of

74:46

heartbreak.

74:47

Yes. Grief.

74:48

Yeah.

74:48

You talked about your father passing

74:50

away from

74:51

Alzheimer's.

74:52

Yes. Well, he had a heart attack. He had

74:55

Alzheimer's dementia when he passed

74:57

away. He he died of a heart attack.

75:00

And just 3 months after your dad's

75:01

death, your younger brother died of an

75:03

unexpected heart attack age 50.

75:05

Yes.

75:06

And you say in your book Good Anxiety in

75:08

chapter 4, you say the death was

75:10

unfathomable.

75:11

Yeah.

75:13

As someone who studied the brain and

75:15

therefore has a really strong

75:17

understanding of the physiology

75:20

of the human mind and has also

75:23

written a book about anxiety, so you

75:25

have this sort of sort of two-pronged

75:26

approach towards understanding feelings

75:28

and emotions.

75:28

Yeah.

75:30

In those moments,

75:32

what did you come to understand about

75:34

the nature of emotion, the most intense

75:37

emotions, and how how they captivate us

75:39

and how we can find our path through the

75:41

jungle?

75:43

Yeah, I like that word that I used. It

75:45

was unfathomable.

75:48

Um um

75:51

both of those losses at at the same

75:53

time, it was hard to process. And I

75:56

remember the waves of grief that would

75:59

come over. It wasn't constant. It was

76:00

like it it would it would it would be

76:02

like waves. So I I have one and then it

76:04

would recede and I felt a little bit

76:06

better. But then unexpectedly it would

76:08

come come again.

76:09

And um

76:11

I'd never

76:12

thank goodness experienced that before.

76:16

And um it was in the middle of writing

76:18

the book Good Anxiety and I I put it

76:20

aside uh cuz I couldn't write when I was

76:24

going through this this terrible grief

76:26

and and I had to do something that I'd

76:28

never ever had to do and actually was my

76:31

biggest fear. Um unnamed biggest fear in

76:35

my life was um

76:37

to have to give a eulogy. I I

76:40

have a fear of

76:43

uncontrollable crying in public and I'd

76:45

always been afraid of of eulogies and

76:48

well, I never had to

76:49

give a eulogy and I had to give this

76:52

eulogy for my for my brother.

76:55

Um, another unfathomable how could that

76:57

be happening?

77:00

And um,

77:02

I I got I got through that and um,

77:07

I learned something in the process and I

77:09

remember

77:11

working out to try and make myself feel

77:13

feel better during this time and um, the

77:17

instructor said

77:19

about the workout with great pain

77:22

comes great wisdom.

77:25

And I just glommed on to that

77:28

that message

77:30

cuz I was feeling great pain. What was

77:32

the wisdom? Like, I need to find some

77:34

wisdom. What what is that wisdom?

77:37

And I realized

77:39

cuz I just say something at this eulogy

77:41

that the wisdom was that on the other

77:45

side of that unfathomable grief that I

77:48

was feeling the only reason why I was

77:51

feeling that unfathomable grief is

77:54

because of the deep love that I had that

77:56

it started with.

77:58

So, if I didn't love them as much, I

78:00

wouldn't have as deep a grief. So, in

78:02

fact

78:04

the grief and the the the depth of it

78:08

was a sign

78:10

of the love that I had for them.

78:14

And that

78:16

that was the wisdom that I found and

78:18

that was the solace that I found and

78:20

that was a message that I gave

78:22

in

78:23

that eulogy.

78:25

And um,

78:26

and then I became obsessed with

78:29

the flip side of these

78:31

awful emotions that we all go through.

78:33

Grief is this one.

78:36

Because I had to go back and finish this

78:37

book, Good Anxiety. I was like, "I'm

78:39

going to do that."

78:41

The book was transformed by that event

78:44

because I realized that if I could find

78:46

the wisdom and the

78:49

the power

78:51

um

78:52

of the most horrible emotion, I'm going

78:55

to say, grief.

78:57

What is the flip side of anxiety?

78:59

What is the gift? What is the superpower

79:01

that comes from anxiety? And I needed to

79:05

find gifts and superpowers.

79:07

And that's why the book got written in

79:09

that way. And I I name superpowers that

79:13

come from anxiety. That was That was

79:16

heightened after after this terrible

79:19

event.

79:20

But I found them and I use them all the

79:23

time. It was therapeutic, actually.

79:26

How did it change you, the loss of your

79:27

brother and your father in such a short

79:29

period of time? How are you a different

79:30

person because of

79:32

those two events?

79:34

You realize that

79:37

everybody's going to

79:38

feel these emotions sometime in their

79:42

life.

79:44

And

79:46

I can

79:48

bring more empathy and compassion

79:50

to those experience for others.

79:53

And I I remember I I never wanted to

79:56

talk to people

79:57

that had a loss. I never knew what to

79:59

say. I knew I was going to say something

80:01

wrong. I just had no idea. I felt lost.

80:06

And um

80:08

and it is I do feel wiser. I feel like I

80:11

have more

80:13

empathy. I have more knowledge.

80:17

Can I ask you a question? If If If there

80:19

was a pill

80:20

Yeah.

80:21

that you could take

80:23

to

80:24

not feel the grief.

80:27

In the moment when you were

80:29

in the throes of that grief, would you

80:31

have taken it? And

80:34

in hindsight now,

80:35

Mhm.

80:36

would you have taken it?

80:38

I look I I know.

80:39

I'm not a

80:41

pill taker. I

80:43

I wasn't clinically

80:45

I didn't feel like I'm oh, I can't, you

80:47

know,

80:48

go about my life. It it it it was

80:51

it was a terrible emotion, but I I

80:53

didn't feel completely debilitated with

80:56

it. Other other people do. Maybe they

80:58

would take the pill. I would not take

80:59

the pill. And after

81:03

the lessons that I learned from going

81:05

through those emotions, absolutely, I

81:07

would not take the pill. And and that

81:09

was part of the lesson of writing this

81:12

book, that anxiety

81:15

is critical for us, because anxiety and

81:19

sadness and and anger

81:22

are critical

81:24

to help us appreciate those joyous

81:28

moments if of our lives. If we had no

81:30

grief, no sadness, no anger ever,

81:35

then every day would, you know, it would

81:37

just be mundane. But it gives that

81:40

value. I mean, our highest highs are

81:43

extra high because we know those lows.

81:46

And and that also is probably how this

81:49

grief that I experienced affects me. I I

81:52

appreciate I appreciate that the good

81:54

times even more.

81:56

As a neuroscientist who understands the

81:58

brain and the systems and then sort of

82:00

neural pathways and all this stuff and

82:01

how we think and

82:04

does that leave much room for

82:05

spirituality

82:07

and

82:08

those kinds of things? Are you

82:10

spiritual?

82:11

I am.

82:12

And what does what You know, cuz when

82:13

some people think about spirituality,

82:15

they think

82:16

it they think it's the opposite of

82:19

neuroscience.

82:20

They think Yes. If I spoke to some

82:22

people, some people that I know, they

82:23

think of

82:24

that the decisions and the feelings and

82:27

the energies are outside of our body,

82:29

not going on in this ball of tofu.

82:30

Mhm.

82:31

And then some like hardcore

82:33

people, scientists, will ex- will

82:35

explain all of our experience through

82:37

this ball of tofu.

82:38

Yes.

82:39

Where do you sit?

82:40

So, um I've evolved over time. So, um

82:43

when I was a young scientist,

82:46

I no spirituality, no religion,

82:49

everything can be described by science.

82:52

Like I have to prove it. Prove it to me.

82:54

I want to, you know, see the data.

82:58

I happily went through um

83:00

that phase for many, many years of my

83:02

life until I realized or I didn't even

83:06

realize.

83:08

I think I needed something more in in my

83:11

life. And and then I realized

83:15

first it was a need. There was a Then

83:17

there was a realization, well,

83:19

can I really prove that

83:22

the only thing that is true is that what

83:26

I

83:27

what I can prove.

83:29

What if there are things beyond

83:31

um proving in the

83:33

in the scientific method.

83:36

And I think there are things that uh in

83:39

the spiritual realm, in the religious

83:41

realm, um

83:43

that

83:45

absolutely could be true.

83:46

Could be true.

83:47

Could be true. That

83:49

cannot be solved, cannot be proven with

83:52

the classic scientific method.

83:54

Things that you believe?

83:55

Yes.

83:58

What makes you believe them?

83:59

Cuz on one hand you said you kind of

84:01

want to.

84:02

Mhm.

84:03

Which is an element of that.

84:04

Yeah.

84:04

But as a I'm interested as a scientist,

84:06

as a neuroscientist,

84:07

Yeah.

84:07

you must have been trained to be able to

84:09

explain. That's how you pass the exams.

84:11

You get You must be able to explain why

84:13

you have these beliefs.

84:14

Do you In that part of your life, do you

84:15

just kind of say

84:17

I've ex- I felt it. Is that the

84:20

No. It's uh Oh, well, part of it, yes. I

84:23

I I do feel it. But it was the

84:26

realization that the scientific method

84:31

in my opinion is not the end-all and

84:33

be-all that I thought it was when I was

84:35

a young scientist. Can you prove that

84:38

these other realms don't exist?

84:42

And if they exist in ways that cannot be

84:44

proved in in a scientific method, well,

84:47

maybe your scientific method is wrong.

84:49

Is that Is that a possibility?

84:51

Have you had an experience that made you

84:52

believe in another realm?

84:54

Have I had an experience? Um

84:57

I have

84:59

in my academic way

85:02

I have studied

85:06

texts that are

85:09

the oldest texts that we know,

85:12

uh the Bible, and I was raised in a

85:16

actually was a half Christian, half

85:17

Buddhist um family. And uh

85:21

but

85:22

my my

85:24

my core belief was

85:26

Christianity. And so, yeah, I I I I go

85:31

to church. I I really appreciate the

85:35

power

85:36

um that

85:38

that religious beliefs bring

85:42

to my life. It actually really decreases

85:45

my anxiety.

85:46

And that's not the only reason why I did

85:48

I just I wasn't look searching for an

85:49

anti-anxiety kind of um

85:53

uh solution.

85:55

But I was

85:57

looking for

86:04

maybe something more than

86:06

the scientific method in my life.

86:10

We're going in one direction as a

86:12

society, like more Yeah, I told you I'm

86:14

basically addicted to my phone. Screens,

86:16

loneliness.

86:17

Yeah.

86:18

Um less connection, less friends, less

86:20

people we can turn to in a time of

86:21

crisis according to all the studies.

86:23

And as we go further and further down

86:25

that road, I think it's making it more

86:27

obvious of

86:28

what's at the end of the other end of

86:29

the street.

86:30

Yeah.

86:31

And it's robbing us of something at a

86:32

really deep level that I think I'm

86:34

noticing more and more as I grow older.

86:35

I think that's actually why I want to

86:36

have kids now because I think I'm in

86:38

search of that greater meaning or

86:40

purpose in my life beyond just like

86:42

making more money or just, you know,

86:45

all the superficial stuff.

86:46

Yeah.

86:46

You You said to me before we started

86:48

speaking that you're thinking a lot

86:49

about community.

86:50

I am.

86:50

Why?

86:51

Because I think it is a balm

86:54

to students and to everybody. And um I

86:58

think those those events that we can

87:00

create that bring people together and

87:02

talking to each other and learning about

87:04

each other are joyous events. And um I

87:07

see it in the in

87:09

in me and in uh the students that come

87:12

to these events. It is clear that that

87:15

is um something that that is a little

87:18

bit unfamiliar to students right now,

87:20

but um has immediate effect.

87:23

What is the one thing we haven't spoke

87:24

about regarding

87:26

Betty, the brain over there in the

87:27

corner, but the brain in front of you.

87:29

The most important thing about the brain

87:30

that we didn't discuss.

87:34

You know,

87:37

you only have one.

87:39

And um

87:40

we have an opportunity every single day

87:45

to make it

87:48

as healthy as it could be.

87:50

I my I watched my father pass away with

87:52

Alzheimer's dementia. And um um

87:56

we have elderly people in my family as

87:58

well. And

88:01

it motivates me even more to to keep my

88:06

brain healthy,

88:07

to make as many friends as I can, to

88:09

have as many connections as I can. Uh

88:13

cuz I want to be as happy as I can be

88:14

for the rest of my life and I want to

88:16

have

88:17

and I want to have a big fat fluffy

88:19

brain.

88:20

So you only have one and

88:23

there are things you can do right now

88:24

today

88:25

to make it stronger.

88:30

Wendy

88:31

Thank you so much. Thank you for

88:35

the way that you deliver I think is so

88:37

deep rooted in a really undeniable

88:39

passion and you you're on a real mission

88:41

to make other people live better lives

88:44

and I think that's something that

88:45

deserves to be

88:47

highly commended. It's it's so apparent

88:49

in everything you do that you're so

88:50

focused on helping others in a way that

88:53

I don't always see um

88:55

and that comes from like you know

88:56

reading through your story I can see the

88:57

pivotal moments throughout your story

88:59

that sent you on that mission and I do

89:00

describe it as a mission. These two

89:02

books are fantastic. You wrote the book

89:04

in 2000 that we published in 2015 called

89:06

Healthy Brain Happy Life and then your

89:08

second book which came out in America

89:10

called Good Anxiety which is a

89:11

phenomenal book that really helps to

89:13

refrain how we think about anxiety. I

89:16

think that reframing helps us experience

89:18

it differently but also shall I say dare

89:20

I say

89:21

be grateful for the signal the lessons

89:23

that it's there to teach us the wisdom

89:24

that it gives us.

89:26

We have a closing tradition on this

89:27

podcast where the last guest leaves a

89:28

question for the next guest not knowing

89:29

who they're leaving it for.

89:30

Mhm.

89:31

Question left for you is in this book.

89:33

Oh.

89:36

What do you think is the best quality of

89:38

humanity?

89:39

Ooh.

89:44

Compassion.

89:47

And what does that mean?

89:48

Compassion means

89:57

feeling

90:00

feeling for the

90:02

um

90:03

um the experience of others both good

90:06

and bad. so I can experience your joy

90:08

compassionately and I could experience

90:10

your grief compassionately. I think that

90:14

is because I've been thinking so much

90:16

about connection and community

90:19

that um

90:21

function of uh or emotion of compassion

90:24

is uh really top of mind for me.

90:28

Wendy, thank you.

90:29

Thank you.

Interactive Summary

In this episode, neuroscientist Wendy Suzuki explores the profound impact of our lifestyle choices on brain health. Emphasizing the concept of 'brain plasticity,' she explains that our brain is not fixed but changes shape based on our activities and habits. She outlines how regular aerobic exercise, healthy social interactions, and mindful practices like meditation can physically grow brain structures like the hippocampus and prefrontal cortex, which are essential for memory, focus, and emotional regulation. Wendy also discusses her research on anxiety, reframing it as a valuable warning system rather than just a negative emotion, and offers actionable strategies for maintaining a healthy, resilient brain.

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