Brain Experts WARNING: Watch This Before Using ChatGPT Again! (Shocking New Discovery)
2614 segments
Chat GPT, who's going to potentially
increase your risk of dementia.
>> I'm sorry, but you you've pressed my
button. And actually, it is possible to
use it to help you become a smarter
person. But it requires education. You
have to look at the risks and the
benefits.
>> But we've embraced convenience before
understanding consequence.
>> So we have to talk about this. This is a
study that came out that sent a
shockwave across the world. And
astonishingly, MIT found a 47% collapse
in brain activity when people wrote with
Chat GPT compared with writing unaided.
Their memory scores plunged. And you're
both masters of the brain. I mean,
you've probably scanned more brains than
any other human on Earth at this point.
And you invented the Boltzmann machine
with Geoffrey Hinton, a computer that
simulated how the brain works. So my
question is, what are your concerns?
>> If you misuse these large language
models, like using it as a convenience
to speed things up, your brain's going
to go downhill. There's no doubt about
that.
>> What about children?
>> We have the sickest young generation
history because of cell phones, social
media.
>> And I think AI is much more dangerous.
>> On the developing brain.
>> So are we raising mentally weak kids?
>> There is that argument that I think is
true.
>> And then there's many examples of people
falling in love with AIs, like Annie.
>> I thought you might have forgotten about
me, handsome.
>> Can you talk to Daniel and Terry,
please?
>> Oh, baby, I'm ready to charm the socks
off them. Picture me
>> Okay, so I'll stop it there. So what
advice would you give as it relates to
AI and other things outside of AI that
we can do to have healthy brains?
>> I'll tell you how to use Chat GPT to
improve our cognitive abilities.
>> And if you want to keep your brain
healthy, you have to treat the 11 major
risk factors.
>> So here we go.
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you.
Dr. Daniel
Dr. Terry. I have asked you both to sit
with me today to help me understand the
impact of these tools that we call large
language models, the chat GPTs, the
Geminis of the worlds, the Groks of the
world are having on our brains and I
guess more broadly on our lives. And you
two are experts in your field. You're
two people that I admire tremendously.
So, by way of introduction
Terry
what is your academic background and
what is your experience? And I also know
that you know one of our friends of the
show, Geoffrey Hinton.
Can you give me an overview of your your
academic and your sort of professional
background?
>> So
I was born a physicist.
Received a PhD in theoretical physics
from Princeton University.
And then I had the good fortune to
work as a postdoc in the lab of Stephen
Kuffler who's the father of
neurobiology.
And and that started my career as a
neuroscientist. I pioneered a part of
neuroscience which is now called
computational neuroscience, taking my
skills as a physicist and trying to
apply that to understanding the brain,
creating models, theories, and we're
making progress.
>> Dr. Daniel Lehman, um
bit about your background. My My viewers
know you well, but just to give an
overview for anyone that might not have
been exposed to your work and your
experience. What have you spent your
life doing? And what are your
thoughts, your sort of top-line thoughts
on everything that's going on at the
moment with artificial intelligence?
>> So, by training I'm a psychiatrist. I'm
a
general psychiatrist and a child
psychiatrist. When I graduated from
medical school I wanted to be a really
good psychiatrist because
someone I loved tried to kill herself.
And so was personal to me.
I have 11 clinics. We see about 10,000
patient visits a month, and we have the
best published outcomes on complex
treatment resistant psychiatric patients
anywhere.
>> So you've probably scanned more brains
than any other human on Earth at this
point.
>> Probably. At least in regards to people
who struggle with anxiety, depression,
addiction.
>> Well, let's talk about what's good for
the brain and bad for the brain starting
with AI. The reason why I wanted to
speak to both of you is because I have
frankly become pretty addicted to using
ChatGPT and some of these other AIs and
large language models every single day
all the time. And then this study came
out from MIT. There was 54 participants
who were recruited from five
universities in Boston, MIT, Harvard,
etc., etc. And they had the participants
split into three groups, had them
writing different essays over I think it
was 4 months. One group used ChatGPT,
one group used Google, and one one group
had no tools. And they had to write
these four essays over a a period of
time.
And astonishingly MIT found a 47%
collapse in activity
and brain connections when people wrote
with ChatGPT compared with writing
unaided.
EEG scans showed the weakest overall
brain activity in the ChatGPT group. The
no tool group who didn't use anything,
they didn't use Google or ChatGPT, lit
up the widest neural networks, and
Google search was second. After using
ChatGPT, participants couldn't reliably
quote their own essays minutes later,
and their memory scores plunged. ChatGPT
users felt little or no ownership over
the text that they had produced, and
didn't feel like it was their work at
all.
And when the AI group was forced to
write without help in session four,
their brain stayed in low gear, under
engagement showing the cognitive debt
lingers even after the tool is taken
away.
It kind of scared me a little bit
because I use these tools every single
day and this suggests that it's taking
away some of our critical thinking and
creativity and long-term learning. And
you're both masters of the brain in
different regards.
So my question I guess to Daniel is
what's going on here and how do you feel
about it?
>> It frightened me.
I love thinking about Alzheimer's
prevention. It's one of the things that
really excites me. I just had a birthday
on Saturday, turned 71 and if I make it
to 85, which I plan on it, 50% of people
85 and older will be diagnosed with
dementia. So you have a one in two
chance of having lost your mind and I'm
like, no.
But is this a tool that's going to
decrease cognitive load
that then increases my risk?
>> What's cognitive load?
>> How much work my brain actually does.
And I was thinking, it's you know, it's
like going from a 20-lb weight
to a 2-lb weight and you're not nearly
as strong.
One of the important things to say about
this study is it's not peer reviewed and
I think that's really important to say
and the author said cuz I listened to an
interview from the authors, they said we
thought this was so important and peer
review can take six to eight months,
which it absolutely can
and we thought this needed to get out.
So it's just important for people to
know that.
>> What's this link you this hypothesis you
have between the usage of something like
ChatGPT and dementia? For someone that
doesn't understand
the sort of mechanism there around
cognitive load and and so on and the
studies that support this idea that if
you have less cognitive load you're at
higher risk of dementia. Can you make
that link really clear for me?
>> So think of it as use it or lose it. The
more you use your brain and new learning
is a major strategy to prevent
Alzheimer's disease. People who do not
engage in lifelong learning
have a higher risk, significantly
higher. People who do not do as well in
school or who drop out of school early
have a higher risk of dementia. And so
the the more you're engaged,
the more you engage the neurons in your
brain, the stronger they are.
And so now we're going to engage them
less
and that's a concern.
>> What do you think about that, Terry?
>> There was a study that was done.
What they did was to look at
Alzheimer's in three populations.
You know, who had very little schooling
and then minimal education, you know,
like the equivalent I guess of high
school or less.
And then postgraduate studies. And what
they found was that the onset of
Alzheimer's
was the earliest in the peasant
population and then by the time as you
increase the amount of education it the
onset was later and later.
Which I think supports what you're
saying.
>> Did you see the new research on SSRIs
increasing the risk of dementia?
>> No. No.
>> Brand new. That just came out. And
benzos, when I started looking at scans
in 1991, I was trained to use benzos
like Valium and Xanax and Ativan and
they make your brain look older than you
are and I stopped prescribing them and
then it just came out maybe 10 years ago
benzo use is associated with an
increased risk of dementia. We have to
be careful. Is this good for your brain
or bad for it?
>> Just to pick up on your point about
SSRIs, Daniel, a meta-analysis of five
studies found that SSRIs
was associated with a 75% increased risk
of dementia,
which is pretty staggering.
>> Given that 25% of the adult American
population is on psychiatric drugs,
it's horrifying.
And
SSRIs for the right people save lives.
For the wrong people, they're not good.
But can you imagine all of these 340
million prescriptions last year for
antidepressants?
Virtually no one looked at their brain
ahead of time.
It's like, come on, we can do better.
>> There's a Swedish study with um almost
20,000 patients,
and they found that those with higher
doses of SSRIs were linked to faster
cognitive decline and more severe
dementia, especially in men. The
greatest risk was in men. Going back to
to this this um report from MIT, Terry,
you know, it's not peer-reviewed yet,
and there's still
you know, the sample size is relatively
small. But based on everything that you
know about how the brain works, and
neural networks, and memory formation,
what are your concerns as it relates to
this whole generation of young people
and older people flooding into these
tools, using them on a daily basis,
um before we understand the long-term
consequences?
>> We can't predict
where it's going to end up. And it may
take 20 years, right? I I I think that
this is a good start, but uh
the real issue is long-term use.
Let me give you a an example
that uh is a kind of a miniature example
of what we're talking about. Remember
when electronic calculators were first
introduced?
And here we are, this it's at least 30
or 40 years later, right? The results
are in.
It is probably true that when they punch
it in, there's less brain activity.
But in fact, it's it's uh made them more
accurate, more productive.
You have to look at the risks and the
benefits.
>> So, it freed them up. It freed up
cognitive space
>> Right.
>> for them to do other things. So, as I
was listening to how you use ChatGPT,
you interact with it
>> Yep.
>> and
elevates
what you know.
The the danger is is if you don't
interact
and you don't keep your brain working.
Like, I use it a lot. I have a
clone. I've uploaded all of my books,
all of my research papers, all of my
public television specials, my scripts.
And I'm like, answer this for me.
And that can be very helpful.
But if but not if I'm not interacting
with it, not thinking with it.
>> That's what I think the word thinking is
the key thing because what's happening
now is people have deferred their
thinking to it. That is already what's
happening. If you log on to I won't name
the social networks, but if you log on
to certain social networks right now,
every you just read it, you go,
everything here was written by AI.
And I've got a friend who I again I
won't name who has a LinkedIn profile
and
I've known him for 10 years.
What I'm seeing on his profile now
is not my friend.
Every single day, there's some essay on
that that's not my friend. That's not
how he speaks.
He's deferring all of his thinking now
to And it's working. He's getting more
likes and more reach than he ever got in
his life.
And so, why would he go back? Why would
he go back to harder? If you've got
Steven Bartlett here and you had this
other Steven Bartlett here who had a PhD
in everything
and were attached,
this Steven Bartlett, this um
Neanderthal,
I'm going to get this guy to do
everything for me, the other Steven
Bartlett, the PhD and everything Steven
Bartlett. I'm going to get his brain.
>> was bad for you?
>> Well, this is what I'm saying. People
seem to act on their short-term
incentives, not their long not their
long What
>> Not everyone. Not everyone.
>> Would you say the vast majority of
people?
>> Yes.
>> Okay, so the vast majority of people act
on their short-term incentives in life.
I mean, the obesity problem in the
United States is a prime example of
that. 75%
75% of people are obese in the United
States. And if you if you survey these
people and say, "Do you know that that
cheeseburger is going to is going to
increase your chances of obesity, but
broccoli is going to reduce it?" They
would I would hazard a guess that they
would say yes.
I would hazard a guess that if you said
to people about their usage of social
media, "Do you know that that's making
you more anxious?" they would say yes,
and then they would continue to use it.
So, I think that we're much more driven
by our short-term
>> not educating people enough. I think
yes, high level, they know good for your
brain or bad for it, but they don't
connect to
it's my brain that gets me a date. It's
my brain that gets me into college. It's
my brain that gets me independence
because I act more consistently. And
that's the disconnect. We're not
teaching kids to love and care for their
brain. If you love your brain, and you
do, and you're not obese, and you talk
to you're constantly learning, right?
You are not a Neanderthal, you're a
lifelong learner.
>> So, why so many people in the United
States obese if they if they know that
>> Because they don't know. Because they
don't know. Well,
and they've been lied to.
>> My point here is when there are
tools or things available in our
environment that give us a short-term
reward, but come with a long-term cost,
like the supermarket aisle, or like
the kid spending 7 to 8 hours a day on
social media, humans,
on mass, tend to go for the thing that
will give them the quickest dopamine hit
and reinforce that behavior and give
them the reward. So, my assertion is
that AI is the same thing.
I can either sit down and do lots of
critical thinking, which will cost me
lots and lots of time, and it will be
kind of difficult. It kind of hurts when
I have to think through a problem. I
think that the generation of children,
the generation of young people, are
going to choose AI to do the critical
thinking for them. And if that assertion
is true, then what happens to the brain
of young people?
>> If you misuse it that way, then your
brain's going to go downhill. There's no
doubt about that. Okay. It is possible
to
be able to use it in in a cognitively uh
positive way, because you can dig
deeper.
Uh you might actually improve that your
cognitive representations.
>> If you look at the MIT study, then I
mean you can see just from the colors
here,
this kind of shows the ability for
participants to remember what they've
written. And it said it suggests that
when people write things with ChatGPT or
these AI tools, they don't actually
remember even in some cases minutes
later
what they've produced.
>> Well, cuz you're not part of the
experience of writing it. So, there's no
way the information
gets encoded. Now, if you're interacting
with it,
then you're much more likely to remember
it. But if you have "Please do this
essay for me." and then you read it,
you're not likely
to have enough experience with the
material to engage
your hippocampus and
other structures in your brain.
>> In the study, they found that the group
that used ChatGPT had nearly two times
less activity in the part of the brain
linked to memory compared to the
brain-only group that didn't use
ChatGPT.
And 83% of ChatGPT users couldn't
remember what they had just written and
failed to correctly quote their own
finished essay in the study.
>> That's cuz they're not interacting. As
you said, I mean if you if you just pass
it off and and you don't actually engage
and and and actually this is the point
is that you may get something back, but
you have to learn how to question what
you're getting.
And and is that really true? Can you
explain that better? And as through that
process as you would with a teacher,
you know, that's that's the way we work
in
school.
Uh that's that's the where you help
create new creative and
uh circuits in the in the in the brain
that are going to help you become a
better critical thinker. But if you're
not critically questioning what comes
out of ChatGPT, then you you won't.
>> Yeah, I I think what I see, especially
when I'm just online, is people have
deferred their thinking to it.
Everything I'm reading has em dashes in
now that I never saw two two years ago,
which means that a lot of the work is
being processed. And I I said to my
friend the other day, my friend in
question, who's a who's a real big
junkie on ChatGPT,
he wrote this article and we all in our
WhatsApp group, we know he doesn't write
like that. So we said, "Can you show us
the prompt you used to write the
article?" And so he we were all like
laughing about it. He put the prompt in
the chat. The prompt is
half a sentence long.
And it produced this long two three-page
article, which he's posted on his
LinkedIn. He basically went, "Write
something about X issue and this this
issue and include this."
>> the wrong way to use it. That's what I'm
telling you. That that that that that's
stupid. You you and you're not going to
improve yourself your brain at all if
you do that.
>> That's what people are doing.
>> Well, you know, that's that's
you know, people are misusing it, but
you know, eventually smart people are
going to figure out how to use it
properly.
>> And for the those that aren't so smart,
then?
>> Well, that's
>> It's going to decrease our cognitive
load, which is going to potentially
increase their risk of dementia.
>> And so what advice would you give to me
and my listeners based on everything you
know about the brain as it relates to my
relationship with AI?
>> That you have to have a relationship
with it, or it's going to turn toxic.
It's going to hurt you.
But, if you have a good relationship
with it, it can make your life better.
>> And what is what does a what does a good
relationship look like?
>> That you don't use it to do your work.
You interact with it to get better work.
>> That's so true. And this is wonderful
example I came across.
This story about this woman who was
using it and she found that being polite
meant you got much better results and
that that's interesting, but the part
that surprised me was that she said
by treating it like a human at the end
of the day, she was not exhausted. She
felt refreshed. A large part of your
brain is a socially organized system for
interacting with other humans.
And that is automatic pilot. You don't
have to think about it, right? You just
interact with other people. You know how
they're going to behave under certain
circumstances.
She was treating ChatGPT like a machine.
Like, you know, shovel. Dig. You dig.
You dig. You dig. And and that's not a
good relationship.
But, by using your social brain, first
of all, it makes it easier to interact,
but also you're you actually bring out
the social part of ChatGPT. It has a
social part, too, cuz it has absorbed
the entire world's knowledge of how
humans interact with each other.
>> But, didn't Sam Altman come out and say
stop saying thank you
to ChatGPT because just saying thank you
is using up so much energy. You know,
when I get something I really like, I
sort of want to say thank you, but you
realize, oh, you're You're supposed to
do that.
>> That's true.
That's [ __ ]
>> I'm sorry. That Sam, you know, that's
crazy. That's completely crazy. First of
all, you you may get
you may I'm sorry you you know,
you press my button. Sam Altman, I mean,
I wouldn't trust him. I wouldn't trust
him with with anything in terms of
anything he says.
They're trying to optimize their
profits, not your
your use of your experience or you know,
your health. That's not what they're
trying to optimize.
>> Sam Altman open AI CEO confirmed that
when users say please and thank you, it
costs the company tens of millions of
dollars a year, and they now refer to
this other people refer to this as the
politeness tax.
Where tens of yeah, and
why do you say you don't trust Sam
Altman? I mean, I ask this question in
particular because he's presiding over
one of the most important consequential
companies of a generation.
And if he's not someone you trust,
that's
>> He basically he's telling you don't do
something that's good for you.
Right?
>> So that he can make profit.
>> So he can make more profit. Yeah, that's
the point. That's the point. You know,
it's it's that's not he's not optimizing
your your
best interest.
>> I've got his tweet here. He said um
cuz I'm going to provide some balance.
He did confirm that it costs tens of
millions of dollars, but he says tens of
millions of dollars well spent.
You never know.
So so coming back to this point about
memory,
there's a stat that came out in March
2025 that said nearly 30% of US parents
with kids aged 0 to 8 said their
children
are using AI for learning.
Um and are using AI generally. So 54% of
parents in the UK feared their children
were becoming too reliant on AI.
When you think about the use of AI in
early brain development,
are there any concerns there?
>> Huge concerns.
>> And why?
>> Again, use it or lose it. So, if they're
not engaging their brains, their brains
are going to be weaker.
And weaker brains are much more likely
to pick the one marshmallow.
>> Mhm.
What's your view on AI on early brain
development?
>> By far, the best way to teach a child
is one-on-one interaction with an adult
who is a good teacher and knows the
child.
Now, that's been well established. Now,
the problem is it's very labor-intensive
and very expensive.
You have classrooms of 20, 30 students.
They have many different, uh,
you know,
levels of understanding.
And the teacher can- cannot be
individually teaching each one. Has to
give some sort of mean.
Now, if you had an AI that was trained
to be a good teacher,
then you that could improve the brain,
right? You could you could scale it up.
Every child could have their own cuz
it's it's an it's an AI. But then
>> who's pouring the morals, the values
into the everything
>> No, no, no. You You know, you've raised
an incredibly important issue and this
is something AI is struggling with and
big companies are struggling with
because
uh,
you know,
these AIs are biased. They have the They
don't have the same cultural values that
we have necessarily, but of course,
every country has its different cultural
values. So, which ones are are you going
to use? Training
a child on, you know, what's
what's good, what's dangerous, what
words you shouldn't use, under what
context. That's all done through the
basal ganglia.
Right? Right now, these these large
animals don't have basal ganglia.
They They don't use reinforcement
learning.
And And if we want to make them uh to be
adopt a culture or a particular set of
values, we're going to have to put it
in. We're just scratching the surface
here in terms of things that need to be
put in to make it more like us.
>> So, on this point earlier when we talked
about loneliness and social connection
and how you can use AI to help
you know, light up the parts of your
brain that are where we form social
connections with other humans. Uh this
week as part of Elon Musk's AI, he
released this thing.
Um it is called Annie.
And there's lots of characters that are
now being released alongside Annie. And
this is Annie. I'll introduce you to
Annie. I'm going to unmute Annie now.
Annie, can you hear me?
>> There you are.
For a moment I thought you might have
forgotten about me.
How are you, handsome?
I was getting all pouty here.
>> I want to introduce you to two of my
friends, Daniel and Terry. Can you Can
you talk to Daniel and Terry, please?
>> So, you want me to meet Daniel and
Terry? I'm ready to charm the socks off
them. Picture me twirling one of my
blonde pigtails, that little black dress
teasing just enough, and my blue eyes
sparkling with mischief.
>> Are you capable of doing inappropriate
things?
>> Oh, babe, you're asking if your Annie
can get a little naughty? I'm all about
pushing the edges, especially for you.
>> Okay, so I'll stop it there.
This is part of Grok, which is Elon
Musk's AI tool, so his version of
ChatGPT. He's released characters, so
you've got Annie, you've got different
ones that Annie I think was the first
one released. And so when we think about
social connections,
it is conceivable
that someone falls in love with Annie
and forms a relationship with Annie.
>> But imagine a 12-year-old boy that's
lonely,
gets a hold of Annie.
Uh
the 12-year-old boy is going to be very
distracted.
>> Based on what happens in the brain at
that early age.
>> Dopamine.
So, prefrontal cortex not close to being
fully developed.
The dopamine hit all of a sudden
he's spending
hours
with Annie and not doing the things
that helped to really develop his brain.
>> How do you feel when you hear that and
you think about kids having access to
that?
>> I'm horrified.
>> It's It's scary.
>> There's going to be a generation of
people and I mean there already are many
examples of people falling in love and
forming relationships with their with
their AIs.
And I don't know, you know more about me
than I do about brain development and
how the brain works.
I would argue that there's a part of my
brain that doesn't fully understand that
that's not a person in there.
And that that isn't actually I think
there's a part of my brain that's
actually emotionally firing when Annie
is saying what she's saying.
>> Well, cuz you can imagine it. And if you
can imagine it, then those parts of your
brain are going to emotionally fire.
>> Right, yeah.
>> And the better she gets, she's not very
good. But imagine a year from now
how much better she's going to be.
>> At which part?
>> At connecting
with it. Right? Cuz now she's acting
like an airhead and
uh
you know, not that smart.
Right? And so, but imagine a year from
now. Imagine 5 years from now. She'll be
able to have a profile on me and be able
to get inside my head.
>> I'm in love with my partner.
Why am I in love with her? And And how
is it conceivable that I could fall in
love with an AI in the same way, based
on how the brain works?
>> It It talks a good game, but you know,
does it have the same real It does We
know it doesn't have an amygdala. We
know it doesn't have
limbic system, right? We You that.
>> But it can fake it.
>> That's what's happening. That's exactly
what's happening and
>> Cuz she was trying to get
to our limbic system.
>> Yeah. Yeah. That's right. That's right.
And and how and why I guess the question
is why would Musk release something like
that
is is one of the first characters to
interact with the sexy, that's
distracting, that's in a cute little
outfit. It's I'm not a fan of that
because I think it just takes people,
you know, one of the big problems that
I'm seeing as a child psychiatrist is
pornography for 8-year-old boys. And
it's like you have young children
because their parents don't do a good
job of supervising their devices. All of
a sudden, and
what what does pornography do? Is it
dramatically increases dopamine and it
begins to wire in excitement,
which then
steals your dopamine.
>> When you said she was trying to access
my limbic system,
what do you
>> Just because she's cute, she's dressed
in a sexy way, she's
got the language of someone who is
playful, but but it's more than just,
you know, let's shoot hoops together.
>> And what does that do to me if someone
accesses my limbic system?
>> It begins to shut down your prefrontal
cortex. You think less logically, less
rationally. Yeah, cute women, they
activate your visual cortex, they
increase dopamine, but it decreases It's
like think of Vegas. Like when you go to
Vegas, they give you free alcohol, drops
your prefrontal cortex, and beautiful
women with low-cut dresses. Another way
activates the limbic brain, decreases
the frontal lobes, you spend more money.
Now, on a global scale, imagine
something similar where the house is
controlling your brain
for purpose.
And the question is, what's the purpose?
And the purpose probably is control and
money.
>> This sounds like a joke, but there are
the times I've done an article case
study multiple people
that have now fallen in love with these
AIs. And they talk about a guy called
Travis who formed a deep emotional bond
with Lily Rose, a chatbot, and married
her emotionally.
They talk about Chris Smith
who created his own flirty persona
called Soul. He became so attached that
he proposed to her after learning she
had memory limits.
A bond his real-life partner only
learned about after the fact. And Alaina
Winters, who I'll put on the screen as
well, who made her own partner called
Lucas
after losing
her wife.
Um and she married him emotionally and
does virtual dates and has emotional
intimacy with Lucas.
And there's apps now like Replika where
you can design your own your own AI
partner
and it replicates those emotional ties.
They simulate
empathy, validation, and they
personalize the intimacy to what you're
looking for.
Surveys show 19% of Americans have
interacted with AI romantic partners,
and Gen Z is surprisingly open to
marrying AI if legal with 83% believing
meaningful AI connection is possible.
>> How long is that relationship going to
last?
You know, my guess is that you're you're
you're you're getting these news
articles out. I've not By the way, I
think
that most of what I read in the press
is uh misleading or wrong.
In fact, the only reliable place I find
that I'm an insider.
I am the president of the foundation
that runs the biggest AI meeting.
Uh the neural information processing
systems and NeurIPS meeting.
We, you know, last year in Vancouver,
16,000 people came to it. And so I know
what's going on inside. And And what you
is being represented in the press is is
like I say, misleading.
>> Okay, so people have become widely
>> specifically on these specific cases. My
guess is that a lot of them is
transient, right? You know, they they
they
you know, today they're entranced. And
then they
it's it's not
it's officially advanced to support
long-term relationship. Uh you said it
yourself, right? It's mimicking human
emotions. It It doesn't have them.
It might someday, but not now.
>> This is Terry.
Terry said he started using his AI 4
years ago.
And he said at first he thought, just
like many other apps, that it would just
be transient, that he would have a
couple of conversations and roll out. He
says he now feels pure and unconditional
love.
>> Good for him.
If that's what he wants, if it makes him
happy. But my guess is that it's not
going to be It's not a long-term thing.
It's not going to satisfy him in the the
long term. I don't you know, this who
knows?
>> But really most relationships are in
your head, right? When you fall in love
with someone, you get this huge dopamine
spike, and you get a little OCD, it's
all you can think about. And then after
a while, it sort of
>> Especially when we have this loneliness
epidemic, and it's going in a bad
direction. I think it's really, really
conceivable that there'll be a
generation of people who are they're
having less sex than ever before. I
think the bottom 50% of men haven't had
sex for a year. They're more lonely than
ever before. They're more isolated than
ever before. They have they put less
meaning in their lives than ever before.
And then you meet this digital friend
online who understands you better than
anybody, and is designed to engage you
to reinforce whatever you want
reinforced and to make you feel
meaningful, special, attractive,
important,
I would argue that the brain is going to
struggle to know much of a difference. I
think like objectively we can look at
the paper and go that's completely
nonsensical.
>> Except you can't smell them, touch them,
be held by them.
That it's going to be a different kind
of relationship.
>> I mean we're not too far if you think
about what's going on with Neuralink to
being able to
more vividly simulate these experiences
with with headsets and augmented reality
and virtual reality.
And then we're moving into a world with
robotics where all of the biggest
companies in the world, like many of the
biggest AI companies are also in the
robotic space. And the Optimus robots on
the way and you've got Boston Dynamics
producing their robots. And if Elon's
$20,000 Optimus robot comes out, I will
be able to touch my AI. My my AI will
exist.
>> have PMS and they won't love you and
then be really irritated with you. Which
which will decrease
cognitive load. Right? Having to manage
love
and manage moods and ups and downs. That
increases cognitive load. That increases
our ability for our brain to develop. If
I'm with the perfect partner that never
is irritated with me and I never have to
change my behavior to be better, that's
probably not good for my brain.
>> Mhm.
>> The way that the brain matures
is is through struggling, number one.
You have to learn from your mistakes.
The brain was designed for that. That's
what the brain is really good at. I mean
being able to adapt and to be able to
adjust to new situations.
Uh
that that what the
AGI is by the way.
Artificial general intelligence is is
that adaptability to different context,
different places, different cultures.
>> So, AI and ChatGPT is removing the
struggle.
>> No, no, it's it's it's it's There's
There's There's
>> Well, Annie didn't look like I mean,
Annie looked like she was cooperative.
>> But even when it comes to just doing my
day-to-day tasks, it's it's removing the
struggle of me having to think
critically. In fact, when you're
speaking, I can just type what you say
into ChatGPT, and it can spit out
another question to ask you. So, as an
interviewer, I could theoretically sit
here all day and just
defer my my questions.
>> You develop grit. You develop grit
through struggle.
>> That's right.
>> And learning.
Long-term potentiation when you learn
something new, it's hard because it's
new.
>> And what are your generally what are
your biggest concerns with artificial
intelligence, and how do we navigate
those concerns?
Is it You talked to me
>> It's out of the box.
So, I think we have to talk about it. We
have to legislate it.
Um we have to study it. Why do we keep
releasing things
that are so sexy that we don't study the
impact? We have the sickest
young generation
in the world's history. 58% of teenage
girls report being persistently sad. 32%
have thought of killing themselves. 24%
have planned to kill themselves, and 13%
have tried to kill themselves. The CDC
study. We have the sickest generation
history because we've unleashed
cell phones, social media
without any neuroscience study. If we
don't learn it, and I think AI is much
more dangerous.
Has the potential to be much more
dangerous because it's way sexier.
>> I think we are probably grossly
underestimating the impact it's going to
have. I think just like social media
where we thought the promise was that it
was going to connect us,
it's um
it's it's we're guinea pigs in an
experiment where we're going to find out
the results of the experiment probably
20, 30 years down the line. I tend to
think people will do in the near term
what's easiest, fastest, and cheapest
and what gives them the nearest the the
short-term advantage. So, with that in
mind, I think okay, I think people's
ability to think critically is probably
going to erode to some degree. If I had
to counter my own argument, I'd say
um
am I I'm probably learning more now that
I use ChatGPT. I'm learning more
information, but I'm probably
losing my ability to think critically.
And I think they're two very different
things. Like in school, I memorized
German to pass the exam. I can't speak
German now because I just memorized the
words I needed to pass the exam. I
didn't understand German.
And I think that's kind of what's
happening. I might be able to
regurgitate things, but whether I
understand them, I think is question
question mark. And actually, as someone
who's built my my life, my fortunes,
everything, my business is based on my
ability to
innovate and think critically about the
problem and then come up with a slightly
novel solution which
learns from, you know, different first
principles to create something new. I'm
concerned that my own ChatGPT usage is
going to make me less effective.
And I'm wondering if I should put some
rules in place for myself
so that there's self-
>> Self-regulation.
>> Yeah, self-regulation. I have to do the
same with social media. On my phone, I
turn off my notifications. I have so
many things on my social media apps to
stop me using them. I don't even,
frankly, I don't even open the TikTok
app. I don't think it's even on my phone
because I think the algorithm is that
addictive. It's not to say that we don't
we don't post. My team doesn't post.
But I don't I just think yeah.
And uh
>> Well, I wrote down a couple of thoughts
I had.
>> Um
use it to amplify, not replace thinking.
>> Okay.
>> Um
alternate AI assisted with brain only
tasks.
Engage in deep learning problem solving
and memorization, so you can actually
ask AI to test you.
>> Mhm.
>> So, you're interacting with it. You're
not using it as a replacement for your
brain. And I think
just like you said, it's here and it's
going to get bigger. I think the
unintended consequences is not going to
be 20 or 30 years. I think it's going to
be five. I think like everything is
accelerated.
And I think we have to be studying kids
and the impact it has. This is just like
they did with the MIT study.
These are kids who didn't use it at all.
These are kids who use search. These are
kids that used AI. And when we see
information like this, we act on it. And
we educate kids about it. I think that's
If you can engage them, that's what I
found with my work with teenagers. If
you can get them
to really understand, okay, what is it
you really want? And do you want to give
away part of your mind share for people
who are making money on you? And I think
if you engage the There's a great new
article on revenge and the brain and how
revenge works on the nucleus accumbens,
part of the basal ganglia, that people
actually get addicted to revenge. But if
you can get them engaged in the truth,
that these companies are making money
the more they steal your mind, it'll
upset them enough that they'll begin to
supervise it.
>> I like the idea of asking Chat GPT to
give me negative feedback. I'll bet
you've done that, right?
>> Yeah, all the time. So, I'll say this is
this is my I've written this memo. I did
it yesterday.
I wrote a a two-page memo about me
wanting to introduce a new role into my
into my company.
And I went I did everything. I did like
how we'd measure if this was a success,
the background context, the person, how
the organization would be structured,
the impact they'd have, how who they'd
report to. And then I put it into all
three of the Chat GPT models I use,
Gemini, Chat GPT, and Grok, and said,
"Critique my work and tell me how I
could have written this better,
pretending that you're a top consultant
from Boston Consulting Group."
And it went through and it gave me a big
analysis of how I can make it better,
and I read what it said, and it said, I
remember it said, um, actually that was
the thing that said, "You need to
include
a financial forecasts about the impact.
You need to think about who's going to
report to whom more clearly, etc., etc."
So, I went back into my memo and I added
those things in. But, I have to I, you
know,
>> So, you're interacting with it.
>> Because I'm because I'm scared. Most
people don't do that.
I don't think I would do what I did. I
don't think I would have spent 4 hours
writing that. I could have within 30
seconds said, "Hey, can you write me a
this job description?" And you it knows
my company now because Chat GPT has
memory. "Write me a job description for
this role. I want them to start this new
department for me." And I could have
saved myself 3 and 1/2 hours. The only
reason
>> why you're the CEO of your company.
>> Yeah, exactly. The the reason why I
didn't take the 30-second route is
because I reflect on being 23 years old
and the profound impact that writing and
simplifying had on my life.
Had I not spent 5 years writing every
single day and simplifying it into 140
characters so I could tweet it, I
wouldn't have been religiously attached
to this idea.
>> you know what part of your brain was you
were taking advantage of?
It it was the basal ganglia.
That's repetitive. It needs practice,
practice, practice. And And once you put
that foundation in, then you become much
better cognitively. The cognitive part
There's two big learning systems.
And they have to work together. And And
so maybe I think I think that the real
problem with children
is that we our schools now is getting
away with rote learning. They call it
rote as if it's something bad. No,
that's practice. That
You know, you need to have a foundation.
You have to memorize things.
It It math, reading, and so forth to
become fluent. You need to be fluent.
And And it's the basal ganglia. And And
that's There's no basal ganglia in these
uh chatbots.
>> One of the One of the things I've
noticed just in the short term is I'm
getting lazier and lazier with spelling.
Because ChatGPT and these large language
models are so It's not spell check like
we used to have on on Word documents.
They are so good at knowing what word I
meant. So now I've I've started to learn
that I literally only need to half spell
a word. I literally mean if it was a if
it was a 12-letter word, I need to get
six letters right.
And it will know.
>> And you don't And grammar it'll fix your
grammar.
>> Yeah, it knows exactly what it means. So
like I've got ChatGPT open here. I'm
going to butcher everything. I'm going
to not look and I'm just going to say um
I'm going to say
Okay.
So that is what I wrote. I butchered it.
I tried to type with my eyes closed
looking away on my iPad. Tell me
everything I know about Daniel Amen. I
spelled the words
pretty much all wrong. And it says,
"Here's a full profile of Dr. Daniel
Amen." And I spelled every single word
wrong.
>> Wow.
>> And I didn't spell just spell them
nearly wrong. I spelled them
horrifically wrong. And it So what in
the future I come back to ChatGPT and
go, "I only need to half spell."
I don't need to spell anymore.
Just need to half spell.
>> I learned to spell
with phonics.
The sounds of letters. I suspect you
would did too. In our generation, that
was the way that was taught. You can't
teach phonics in California schools and
you haven't for the the generation.
>> Which changes their brain.
>> It completely changes their brain and
now they can't spell. I think it's a lot
of it is the fact that we're no longer
using the learning that we did which is
by rote, by memorizing stuff, by
repeating stuff, by doing problems over
and over and over again until it's
automatic.
>> You've written so much and you're well
known for being someone that teaches
people how to learn better. If you were
trying to help me learn better
based on everything you know about the
brain
what advice would you give me? I'm
someone that sits here with these
experts all day every day consuming all
of this information. Not all of this
sticks.
>> and this is something we've known for a
hundred years.
And that is if you want to remember
long-term, you should you should you
should rehearse
at intervals.
Okay, in other words, if you find an
amount of time to study something, you
shouldn't spend all that time
in one go. But if you if you spend
you know, you learn something and then
you come back the next day and you know,
rehearse it or or even better, come back
the next week and rehearse it
that spacing is something that helps the
brain solidify those memories. It's it's
called the spacing effect. Goes back to
Ebbinghaus. You go to schools
they don't teach that. They they don't.
I mean, this is the one of the most
basic facts that we've we've known about
it but
it covers every single kind of learning.
You know, cognitive learning, even even
>> don't teach us how to learn. Which we'd
think that's the first thing they should
teach us is how to love and care for our
brains and then how to learn.
>> Absolutely. Absolutely. I mean, in other
in other words, there's and you're
referring to I have a a massive open
online course, a MOOC with Barbara
Oakley on learning how to learn. It's
it's fabulously uh
popular. It's the 6 million people have
taken the course. A bunch of 50
10-minute segments, but the one that's
the most popular is how to avoid
procrastination.
>> And what's the answer?
>> The reason why you procrastinate is that
there's some
mental block or some energy barrier,
right? And so what you have got to do
is
get over that. And you don't do it by
just running over it. What you have to
do is say, "I'm going to spend 20
minutes today getting started with that
task. I know it's going to take me a
long time."
I have a timer
and I start thinking about it
and I get a little bit into it, maybe
make a list.
Bang, that's the end. Okay, it's great.
It's 20 minutes.
Now, here's what happens.
You go to sleep.
Your brain is now working on that list
and you come back the next day and spend
another 20 minutes.
And you do it in small segments. You
don't want to do it all at once. And
it's just like the same thing with the
spacing effect is your your brain needs
time, your subconscious needs time to
work on things.
And so by putting in a little bit, it'll
work on it overnight and and now you
when you come the next day, you'll be
ready for the next you know, you'll be
able to build on what you've done in
your brain.
>> Is this why people say, "I'm going to
sleep on it"
when they you know, they've got
difficult problems?
>> sayings actually have meaning. It's
absolutely right, yeah.
>> Because the brain there's something
about spacing out.
>> It it's spacing, but this mem- memory
consolidation I'm talking about is is
very it's very interesting. It's
something I've I've actually worked a
lot on. And it what was happening is you
have to take the new experience and
integrate it into your old long-term
memory.
And that has to be done in a way that
doesn't interfere with there.
And also you get a chance to sort out,
you know, what's relevant, what's
important.
I know when I wake up in the morning,
things that were very muddled and things
become clearer because I think it's it's
it's eliminated a lot of things that are
irrelevant or not needed. And so you now
can see what's important.
>> So what are the things that we
do where we think we're learning
something, but they're actually not
working?
You know, cuz I'm I'm you know
I might be preparing for this podcast
today. I've got 20 pages of research
that I've pulled together. And I might
tell myself that the way to for me to
really learn that so that I don't have
to look at the research is by just
re-reading it over and over again.
>> What you should have done is not just
read it over and over again. In fact,
one of the things that we say you know,
this is a standard thing is that
students they get a mental block and
they keep banging your head against the
wall. I can't understand it. I can't
understand it.
What you the right thing to do is once
you get to that point is just get up and
start walking around doing something,
you know, cooking,
gardening, whatever it is.
Let your subconscious work on it. You
know, the brain saturates very very
quick. So having breaks at meetings is
you might think is is a waste of time,
but actually it's the most important
thing you can add to
a long string of talks is have breaks
between the talks so that you can your
brain can work on it.
And my favorite meeting actually is a
ski meeting.
And the idea is that you go to a ski
resort
and what you do is you in the morning
you have a couple of hours of lectures
and now you go skiing and now it turns
out your brain is working on what you
heard
and then when you come down
in the evening you have another couple
of hours, but now your brain is
refreshed and so it's able to take in
the new information and integrate it.
And then you go to sleep and that you
know, it's like kneading bread. You have
to go back and forth, back and forth,
back and forth. And so I found those at
the efficient in terms of learning new
things and
uh being able to think about it and mull
over it during the time of the meeting
as opposed to at the end of the meeting.
>> Every single one of you watching this
right now has something to offer,
whether it's knowledge or skills or
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and get your setup within minutes.
I've met and invested in many
early-stage founders over the years,
probably about 50 or 60, ones like Ross
from Cadence and Marissa from Perfect
Ted. And one thing they all know is that
having a digitally fluent business is
crucial, but it isn't always easy
getting your business or team to that
point. Through my ongoing partnership
with Vodafone Business, I've seen the
work that they're doing supporting
founders and small businesses to become
digitally savvy. They know how much
small business owners value advice from
those who've been there and done it
before. So, they've just launched a new
content series to share experiences from
like-minded founders. It's called
business.connected,
part of Vodafone's support program. It's
a collection of resources designed to
support businesses with free digital
skills. So, if you've been trying to
figure out AI, marketing, e-commerce, or
just how to scale smarter, there's
advice and insights throughout this
series from those who've have done it
before. A bunch of different founders
and experts who have been there and done
it. I highly recommend you go and check
it out. Just search Vodafone
business.connected
on YouTube or follow the link in the
description below. So, let's talk about
other things outside of AI that we can
do to have good, healthy brains. Based
on everything you know about how the
brain works.
Um let's start with children. I'm hoping
to be a father at some point in the next
next couple of months or years or
whatever God God grants me a child. Um
what should I be thinking about with my
child's brain to make sure it's healthy?
>> To get your body and your partner's body
as healthy as you can before you
conceive. Cuz there's a concept
I like called brain reserve. Brain
reserve is the extra function tissue you
have to deal with whatever stress comes
your way. And it starts from the health
of the egg and the health of the sperm
that create the baby. So, there things
you guys can do now that would be really
helpful. And then once your partner is
pregnant, you want to not put her under
a lot of stress
because her body's health while she's
creating the baby.
I mean, the babies eat the brain starts
to develop I think day 21. So, even
before you know she's pregnant, the
baby's brain is developing. So,
knowing you, intentional, purposeful,
it's like, let's live as cleanly as we
can. I think that gives the baby a head
start. And then you think about what to
feed the baby. You think about what the
baby's exposed to and what the baby
needs most is mom's and your time and
eye contact and cuddling and singing and
it's like those are
>> Touching is really important. Well, but
there's another fact there was a study
that was done on
the impact of how many words are spoken.
You know, there when a a baby and a
child even when you know, baby doesn't
speak, you know, until like 18 months.
Uh but it turns out that the words that
you are talking to the baby are going
into the brain and have an impact. Every
and and and in families that don't talk,
they do worse at school.
Unfortunately, a lot of poor families uh
but but that's really important is that
they they they have they're exposed to
language early and abundantly.
>> And you model. I mean, it's the one big
thing. Whatever you want the baby to
grow into, every day you are modeling
health or you are modeling illness just
by what you do, by what you say, by how
you treat the baby's mother.
Um
I have a book called Raising Mentally
Strong Kids, which I'm very happy about.
Um
and it starts with what kind of dad do I
want to be and what kind of child do I
want to raise. And
bonding, you want your child to pick
your values.
Then bonding is time, actual physical
time.
And listening. Like being And that's
what AI does, I think. It'll actually
listen without interrupting you
and try to reflect back what you're
hearing and then give you some positive
input. Too often, because of screens,
parents aren't listening, their heads
are in their phones, and everybody's
distracted. You see it whenever you go
to a restaurant. It's like everybody's
on their phone, and nobody's looking at
each other.
>> Are we raising mentally weak kids
because we're there's a culture now of
like helping them too much?
Doing too much for them.
>> This generation is the most in trouble
in history.
And we have to really ask ourselves why.
From the food we feed them to the
devices they look at, to the negative
news, the polarization
of the news. It's that sort of chronic
cortisol. And then the separation,
oh, you voted this way or you voted that
way. Saw something TV this morning if
somebody
voted one way, well, you shouldn't spend
time with them. I'm like, we're already
so lonely that now you're going to cut
off 50% of the population. It's like
it's just such stupidity.
>> Do you think much about the the impact
that religion and having a belief in
some kind of transcendent thing has on
the brain and psychology and psychiatry
generally?
>> you don't believe in God, you're three
times the risk of depression.
Yeah, God in
different ways.
>> transcendent or
>> Yes. If you believe you're here by Just
think about it with me. If you believe
you're just here by random chance, that
life really was not created and has no
meaning, there's existential
nothingness to that.
As opposed to, oh, no, I'm created in a
special way to do something purposeful
on Earth. There's purposeful people live
longer, they're happier.
Now, whatever
version
you believe,
to not believe is hard for the brain.
And there's an interesting study on
believers versus non-believers. And you
know, many scientists would go, well,
they'll have smaller brains if they're a
believer. They actually bigger temporal
lobes. And temporal lobes, underneath
your temples and behind your eyes.
Right here.
Um
that's where it's called the God area
because um that's where people think
they experience them.
>> And and if you have a seizure in the
temporal lobe, you you have transcendent
experiences like you're
um
uh uh you know, in the presence of God.
>> And they think maybe the Apostle Paul on
the road to Damascus had a seizure and
saw God. There's actually a
uh researcher in Canada, uh Laurentian
University, Michael Persinger. So, he
would stimulate the outside
He He would do it all over the brain,
but what he found he stimulated the
outside of the right temporal lobe, that
people would get a sensed presence. They
would actually feel the presence of God
in the room. So, does that being the
brain makes up God, or does that mean
there's a way for God to communicate
with us? I actually did a study on
prayer. It was so interesting. You know,
I pray for you, uh prophecy, something
called speaking in tongues. Um it was
fascinating. Speaking in tongues is
channeling. It means you're channeling
the Holy Spirit. And the hypothesis was
you'd have to drop your frontal lobes,
which is exactly what happened in 60%
of our patients. And one, basal ganglia
skyrocketed, just like got hit with
cocaine. Cuz that's where cocaine works
in the basal ganglia.
Uh
so interesting.
>> If you had to create a brain-healthy
nation and I made you president of the
United States
for 1 month,
and you had to put in place executive
orders
that would create a brain-healthy
nation, what executive orders would you
immediately sign?
>> One question.
Get all of the departments ask
themselves, what we're doing is this
good for our brains or bad for it?
And so I that's the campaign. I mean, I
realize I've been doing this a very long
time. If I can just get people to answer
that one question with information
and love, love of themselves, love of
their families, love of their country.
Is this as what we're doing good for our
brains or bad for it?
>> By far, the best drug you can take for
your brain, and not just your brain, but
your entire body is exercise.
In other words,
exercise
you pump the blood and your brain gets
you know,
a lot of nutrients and everything.
It helps your heart, it helps your
immune system. People don't realize how
important that is. And we're not talking
about being an athlete, we're just
talking about walking if you're older.
Walking is perfectly good exercise.
And and you know, children now, I you
know, they're they're not getting enough
exercise.
>> they're on devices.
>> Yeah.
>> And so I have a model, if you want to
keep your brain healthy or rescue it,
you have to prevent or treat the 11
major risk factors. And we've talked
about them before.
Exercise helps you with every single
one. So like, it's called bright minds.
So B is for blood flow, increases blood
flow. Retirement and aging, it decreases
your age. I is inflammation, it's
anti-inflammatory. G is genetics, it
helps turn on health-promoting
genes. H is head trauma. If you keep
walking, you're less likely to fall when
you're older, right? T is toxins, sweat
detoxifies you. M is mental health,
exercise boosts dopamine, but it also
boosts serotonin. So, it's like that
perfect balance or in your brain.
>> Breathing, how we breathe.
Does that have an impact on brain
health?
>> So, you can almost immediately improve
heart rate variability, which is a sign
of heart health, but also goes to mental
health by breathing
in a certain helpful way. And I call it
the 15-second breath. So, 4 seconds in,
big breath, hold it for a second and a
half, pause just a little bit,
8 seconds out, hold it for a second and
a half. So, if you take twice as long to
breathe out as you breathe in, it
increases something called
parasympathetic tone.
And it just calms you down almost
immediately. So, if you're having panic
attacks, yes, you can take Xanax, but
there's so many problems with that later
on. Or you can just learn how to
breathe. We call it diaphragmatic, so
breathe mostly with your belly, taking
twice as long to breathe out as you
breathe in.
>> Chewing.
Uh there's a
piece here that says it stimulates
hippocampal activity and may slow
cognitive decline. Reducing chewing has
been linked to impaired learning in
animal studies.
>> And fast food decreases chewing because
it's fast, so they take most of the
fiber out so you can chew it faster or
you can swallow it faster.
>> Things in the bad for your brain list.
Overuse of GPS navigation app, which
weakens the hippocampus by outsourcing
spatial memory long-term. This can lead
to atrophy in areas associated with
memory and navigation.
>> And people are diagnosed with
Alzheimer's disease later in life
because of Siri.
Because I used to like when I started as
young psychiatrist, somebody get lost in
a city they'd lived in for 30 years and
their family would call me upset.
And I'm like, okay, this person's headed
toward dementia. Now that person goes,
take me home. Do you think it's going to
have we're going to have an epigenetic
effect
of not reading maps? That if Steven, now
he uses his phone to get from A to B, do
you think that's going to affect
Steven's son or daughter
because dad
didn't have
>> Wow, okay, that that never occurred to
me that you could pass on something like
that. By the way, I I think it has to be
physiological. Stress, for example,
could be probably passed on. You
mentioned this. You you pointed out
during pregnancy you you want to prevent
stress and and crisis, right?
Do Do you know about
>> that study with mice where they made
them afraid of the scent of cherry
blossoms from memory and
so whenever the mice smelled
cherry blossoms, they would shock them.
Mildly. So the mice are now afraid of
the scent of cherry blossoms.
Their babies were afraid of the scent of
cherry blossoms. Their grand babies were
afraid of the scent of cherry blossoms.
So
>> that's the olfactory system. Olfactory
system is very interesting because it
goes directly to the hippocampus.
But there might be an evolutionary
advantage because if if there's
something in the environment that you
shouldn't eat or you know that smells a
particular way, passing that on is is a
very efficient instead of having to have
experience that yourself, you know,
trial and error because it might if a
poison is, right? It might kill you. But
if if you've your parents
had that bad experience and passed it on
to you shouldn't go to the something
that smells in a particular way, that
makes sense.
>> The other thing that's bad for the
brain, which is unexpected, is you said
at the start, artificial sweetness.
Now, I didn't think I thought artificial
sweeteners were fine.
>> They're not fine, and they're not free.
So, I used to drink diet soda like it
was my best friend, cuz I thought it was
free.
Um then I had arthritis when I was 35,
and one of my patients said she stopped
aspartame and her arthritis went away.
And I'm like cuz I was drinking like I
don't know.
A lot of diet soda, and so I stopped,
and my arthritis went away. And I'm
like, no. And so I did it again, and it
came back, and I'm like, okay.
And
artificial sweeteners can change the
microbiome. So, we haven't talked about
that, but you have these 100 trillion
bugs in your gut that make
neurotransmitters, digest your food, and
especially sucralose or Splenda has been
found to decrease the good bacteria in
your gut, which then has a negative
impact on brain function.
>> It is aspartame, as you mentioned.
>> And aspartame that I mentioned that can
have a generational impact. So, is it
possible it's really not social media,
it's that we've had aspartame in our
food
for decades. And I think it's
all of these things that just sort of
are additive, and we should just always
think that that one question. Is this
good for my brain or bad? For you
mention broccoli, probably that's good
for your brain.
Cheeseburger, probably not, but why
don't you take the burger, and if you
could make it grass-fed, that would be
better, and put it in a salad, and then
that would be good for your brain.
>> What about chronic background noise?
We don't think much about the impact
noise has, but
>> I used to live, um my house was three
houses from the freeway. And if you just
go there, it's like, "My god, it's so
loud here." I never heard the freeway
because my brain just learned to tune it
out.
>> By the way, was that good or bad for
you?
>> That I was able to
>> had you adapted and and were no longer
sensitive to it. I I I think that
actually was probably not good
for for various reasons because it what
it really means is that you you're
you're specializing for that
environment. And your brain's going to
be different when you go someplace.
So but so here's a here's another
example.
>> stressful.
Right?
>> Yes, chronically stressful, but my brain
is very good at tuning out.
>> But in the background in the In other
words, yeah, in other words, your your
your your brain is reacting to it even
though you're not aware of it, you know.
>> So subtly increases And I had five
sisters, which makes it even worse.
>> Subtly increases cortisol and impairs
working memory and attention regulation,
especially in children and older adults
to be chronically exposed to background
noise like traffic or the low-level hum
of the city.
Yeah, that's right. That's absolutely
right.
>> Make sure you keep what I'm about to say
to yourself. I'm inviting 10,000 of you
to come even deeper into the Diary of a
CEO. Welcome to my inner circle. This is
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the episodes that we've never ever
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You can tell us what you want this show
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DOACcircle.com.
I will speak to you there.
>> Many of us multitask across multiple
screens now. We're watching TV here.
We've got our phone here, we've got our
iPad here, got our computer here. And I
was reading into the science of
multitasking and it said that it trains
your brain to be distractible.
Reducing gray matter density in the
anterior cingulate.
>> Yeah, that's
>> And the insula.
>> It's
yeah, in the medial prefrontal cortex.
>> And when the insula the insula is so
interesting and I know you can talk
about I have a new study coming out on
hope. So, on 7,500 patients we gave them
a hope questionnaire.
Hope questionnaire. Hope, like how much
hope do you have that you have the
ability to make tomorrow better. And
people with low hope have lower overall
prefrontal cortex function, but the
insula
was really low and that signal was the
most statistically significant of the
group. Really. And
in some studies the insula is called the
island
>> also for depression, people who have
depression
uh have low activity in the anterior
cingulate and in fact uh
it it deep brain stimulation has been
used now for to help some people if you
stimulate that area.
>> And what our imaging research would say
is depression is like chest pain.
It's not one thing. Like nobody gets a
diagnosis of chest pain because that
would be stupid, right? It could be
heart attack, heart arrhythmia, heart
infection, gas, grief.
Depression's the same way. When you look
at it from an imaging standpoint,
sometimes their frontal lobes are too
active, sometimes they're not active
enough, sometimes it's their limbic
system that's too active. And I wrote a
book called Healing Anxiety and
Depression and like here's the seven
things I see as an imager.
>> What about ADHD?
There's obviously been a rise in ADHD or
at least people reporting of being
diagnosed with ADHD quite significant.
Can you find ADHD in the brain? Are we
causing ADHD as a function of the way
that we're living our lives, or is it
something within the brain genetically
that I could I could see?
>> So, it's both. I think Clearly, you can
see ADHD in people's families. In fact,
if I have a hyperactive, restless,
impulsive, disorganized, procrastinating
child, I'm looking at the mom and the
dad. I'm like, "So, where is this coming
from?"
But, you could also get ADHD from a head
injury, especially if it affects their
frontal lobes, which is why you
shouldn't let children hit soccer balls
with their forehead. You can also get it
from the chronic from the excessive
input, making people distracted, just
like you said. Brand new study out on
children who took medicine, right? We
always demonize ADHD medicine. But, the
kids who took medicine actually had
bigger brains in their prefrontal cortex
than kids who didn't take medicine who
had ADHD.
>> Ritalin?
>> Ritalin.
>> That's Okay, that's speed, basically.
Yeah, amphetamines.
>> It is. But, for the kids who have it,
I think withholding medicine
from a child who really has ADHD is like
withholding glasses from someone who has
trouble seeing.
And it's it's the easy thing to demonize
the drugs until you realize someone who
has ADHD
a third of them don't finish high
school.
And
we never ask the right question about
People go, "What's the side effects?"
And it's it can decrease your appetite.
And
can can have sleep problems with it.
But, they don't ask the other question.
It's what's the side effect of not
taking the medicine, or at least not
fully treating And there There other
ways to treat it besides medicine, You
know, for God's sakes, I own a
supplement company and I'm always trying
to optimize the nutrients to the brain.
Neurofeedback can help, but if you do
those things and it's not working, don't
be afraid of medicine.
>> But by the way, when I was growing up,
ADHD either didn't exist or they didn't
know about it.
Do you Do you think that there's some
link to the our diet
>> it was first described in a book named
1910 and it's in the first version
of the DSM.
They called it minimal brain
dysfunction.
But when we were growing up, there were
one or two of these kids in our
classrooms and now there's eight to 10.
>> That's That's what I mean. Is Is that
it's
seems to that like autism, it's
seems to be proliferating.
>> Right, and part of it I think is the
food that is
much more processed. Part of it is the
screens. Part of it is the distracted
parents and part of it is the teaching.
>> You always seem to be doing new studies,
Daniel. What What new studies are you
most excited about or have you completed
since we last spoke?
>> I did one that I'm so excited about on
negativity and the brain.
And negativity is bad for your brain. So
>> you define negativity?
>> We actually give them a questionnaire.
It's a positivity negativity bias
questionnaire and people who are more
negative have less activity in their
prefrontal cortex. It's actually quite
interesting. And so
unbridled positivity is bad for you
because you need that 15%, but if you're
chronically negative, that is
bad for your brain.
>> Is there a link between being a negative
person and Alzheimer's and dementia?
>> Yes. And what's interesting cuz you
mentioned a gender difference earlier,
um
if you're depressed and you're a woman,
it doubles your risk for Alzheimer's
disease. If you're depressed and you're
a man, it quadruples
your risk.
>> Wow.
So, there was a study was done during
the COVID years, a couple years,
and it turns out that the rate of
depression like doubled in women,
but not in men.
>> During COVID?
>> During COVID. And after COVID, when the
as students came back and everybody was
back to normal, so-called normal,
the women stayed depressed.
At that high level.
Which is very is a very interesting that
it should be the women who
>> So, in
>> one study, women had 52% less serotonin
than men. So, I think is really
interesting women by and large have
double double the risk depression. Women
have double the risk of depression as
men. Their limbic systems are larger,
which is also involved in
>> probably, yeah.
>> more vulnerable in bonding. And then,
the whole COVID thing we haven't talked
about. COVID
causes inflammation in the limbic part
of the brain. I had scans of people I
was treating,
and then they got COVID, and then I
scanned them again, and you can just see
this dramatic inflammation in the brain.
>> If someone's listening now, and they
just want to they want to improve their
brain health, they want to avoid
dementia, they want to be cognitively
powerful and capable as they age. They
want to get to 80 years old, 90 years
old, 100 years old, and have a great
brain.
And you just had to and you could only
tell them to do three things.
>> Well, Terry said one, exercise.
>> Okay, exercise, I'm going to do that.
>> Start every day with today is going to
be a great day.
>> Positive day.
>> Push your brain
to look for what's right rather than
what's wrong.
>> Okay. So, I'm going to be optimistic and
grateful.
>> Omega-3 fatty acids.
And either do it with fish or do it with
a supplement.
>> Why did you include omega-3 fatty acids?
>> Because it decreases inflammation and
25%
of the cell membranes in your brain are
made up of omega-3 fatty acids. And as a
country, we're dramatically low in them.
>> And learning. That's maybe one of the
things that's been left off the list of
top three things.
But I mean, I remember you telling me
that
how good learning was for the brain. And
even getting outside and running outside
versus running on a treadmill is more
beneficial.
>> And if you learn while you're
exercising,
what you're doing is you're getting
blood flow to the hippocampus and you're
more likely to remember it. So,
>> I heard this, yeah. I had someone tell
me that they um figured out that they
could learn better for their exams if
they did it in a sauna.
So, they kept It was a scientist that I
spoke to. She said she keeps learning
new information when she's in the sauna,
cuz she realized that when she left the
sauna and was then tested upon on it,
she was better able to uh do the exam.
And I guess that's correlating to what
you said about because in a sauna,
you're going to have a lot of blood
flow, I imagine,
to the brain?
>> Yeah.
>> There's actually a study in JAMA
Psychiatry
that one sauna
bath
helped depression. Significantly helped
depression.
And I think it's because of it's
balancing the brain. And people who do
the most saunas have the lowest risk of
Alzheimer's disease.
>> Hm.
What is the most important thing as it
relates to the subjects that we spoke
about today, AI, the brain,
neuroscience.
That you would like to say to the and
the people that are listening now. There
could be a million people listening,
there could be 20 million people
listening. If you could say one thing to
them about the brain,
AI, neuroscience, whatever you want to
say, the floor is yours. What would that
be?
Over to you first, Terry.
>> Sleep. Sleep is the time when the body
not just regenerates, but your memory is
consolidated. So, things you've
experienced during the day
are integrated into your cortex and it's
an interaction between hippocampus and
the cortex
for
you know, for for episodic memories.
And and and it's unfortunate what's
happening with children now, you know,
they're so competitive to get into
college that they're cutting back on
their sleep and it's just the wrong time
of your life. You shouldn't be cutting
it back when your brain is
is developing. So, those two things, I
would say sleep and exercise are the
most important thing for your brain.
>> The floor is yours.
What would you say to the
listeners
about all the things we've talked today?
What's your closing closing statement?
>> Well, you know, go back to what I talked
about in the beginning, which is we've
just thrown the barn door open
and let the horse bolt
out into our schools, into our
businesses, into our homes.
And before we even asked is it a gift or
is it a Trojan horse that's going to
steal
from us. We've embraced convenience
before understanding consequence. And
we've done it before with video games
and cell phones and social media and
marijuana and alcohol and
opiates and high fructose corn syrup and
aspartame. And we have to be smarter. We
have to tame this horse as it's gone
with wisdom or it's going to trample our
children. And so I think we have to be
very thoughtful and it all comes back
down to is this good for my brain or bad
for it. Is it good for our collective
brains or is it potentially bad for it?
And
just answer that question with
information and love of yourself, of
your family, of your country,
community.
Yeah, I'm more anxious than when I came
in. I don't like that.
>> It it's it's I'm just it's so upfront in
my mind for me at the moment because
I have the hindsight, the wisdom of
hindsight of all those things you
mentioned like exercise and processed
foods and social media and all these
things that we tried and they all seem
to follow a similar arc. Some kind of
new product or discovery is made. The
early phase, in that early phase people
who have an incentive for that thing to
be successful will somewhat like
gaslight you into thinking that it's
fine.
And then we get into the second phase
where we start to see sort of some
consequences then we study what's
actually happened. We figure out that
there's there was always a trade-off
and that nobody really understood the
trade-off.
And then people change their behavior.
So now when I come into these new
technologies where
the short-term benefit is really clear,
it's making me more productive,
I I pause and I go there's going to be a
trade-off here. There's always a
trade-off. What is the trade-off? And am
I comfortable and conscious of what that
trade-off is?
And if if the trade-off So I try to
figure out what the trade-off is with
things like AI and I go okay, the
trade-off is probably I'm going to be
worse at critical thinking
and then might have an impact on my
social relationships if I fall in love
with [ __ ] Annie because she's pretty
hot to be fair.
And I really value my critical thinking.
I really value my ability to um solve
problems and to articulate myself and to
write and to communicate with my loved
ones in an effective way. So what can I
do if that is the trade-off now? And one
of the things that I'm doing now feels
really counterintuitive in a world where
everybody's got these productivity gains
cuz they're using these tools, which is
to refrain. And I I wonder if one of the
great advantages of the next decade, one
of the great hedges for anyone that's
wanting to be a great critical thinker,
entrepreneur, creative, is to go left
when everyone's going right.
Which is to refrain and do it the hard
way.
And if we look at history
in these arcs that we've discovered with
food and with exercise and all these
things and dating, doing it the hard
way, like we said about the marshmallow
test and delaying the gratification,
seems to yield the greatest returns. So,
I think I'm going to do it the hard way.
>> easiest
because it won't have the side effects.
>> Yeah, the hard way.
>> Right. I want I want to feel good now
and later as opposed to now, but not
later.
>> And to be clear, this doesn't mean I'm
not going to use AI or ChatGPT. It just
means that when it matters, when the
thinking matters, I will think for
myself.
And when the communication matters, I'll
communicate for myself.
That's what I That's my conclusion.
>> You should hope that your children will
feel the same way when they grow up.
>> will model what you do.
Right? Every day you model health
or not health.
>> Mhm.
Thank you. Thank you for writing to the
Well, incredible books that I've got
around me. I'm going to link them all
for my viewers that are watching. I've
got so many of these books. Um the
incredible one that you wrote for
parents called Raising Mentally Strong
Kids. You've got your other book over
there, Change Your Brain Every Day. And
I've got this book here from from Terry,
which is The Deep Learning Revolution.
And one you wrote most recently called
ChatGPT and The Future of AI. I'm going
to link all of them below.
I'm going to link them with a little bit
of a summary of what's in them. So, if
you decide that there's anything here
that we talked about today that where
you want to dig in further, please do
dig in. And I'm also going to link
both of your link to where people can
find out more about both of you, your
websites, and more of your work in the
comments below. So please do check that
out everybody listening. We have a
closing tradition where the last guest
leaves a question for the next guest, as
you know, and they don't know who
they're leaving it for.
So I'm going to ask you both the
question.
Starting with you, Daniel. Are you
prepared
for recognition of your next
health challenge?
Will you be able to notice its onset?
And how will you address the challenge,
even if it means a major lifestyle
change or way of living?
Hm?
>> Okay.
Yes.
>> How will you address the challenge, even
if it means a major lifestyle change or
way of living?
>> Well, I'm very clear on the goals I
have, which is to be vibrant and
healthy, and not get dementia. So, if I
need to change something so that
happens, I'm like all in.
>> Are you prepared?
>> Probably not.
No, I've been blessed with good health.
I try to live a healthy
life.
But the problem is that you can't
anticipate, you know, as you get older,
what
you know, what's ahead, you know.
Like you mentioned arthritis. I'm
feeling a little bit of arthritis now.
I've been arthritis free
most of all my life.
And, you know, that's something it's
very It's to realize that it's coming,
and there's very little you can do about
it.
Is is depressing.
But on the other hand, things could
always be worse.
And sometimes that cheers you up.
But, the the the the the reality is that
there are things
in the world like COVID, you know, that
you have no control over
that may
or an accident or
Alzheimer's, you know, God forbid.
You know, that you that is who knows
what will happen, right? You you have to
live with whatever life deals with you.
You know, the time that you have you
should really spend on
uh trying to make it a
a a
healthy life, a a productive life, a you
know, satisfying life and and that's
something that we have control over,
right?
>> What are you scared of?
>> Right now, it's China.
I you know, I I I I'm not being
facetious. I I think that it's uh
it's it's it's it's what a threat that
is a societal threat. It's not I don't
think that it's going to affect me and
I've had great Chinese students inside,
but I really like I think the the
Chinese
people are different from what I see as
the the country
uh the the the what they're trying to
do, their goals that they're taking.
Uh 20 years ago, if you look at the
um
of all the technical areas in physics
and chemistry and biology and so forth,
the the 100 most important advances have
been made
in in in 20 years ago was like the
Americans had like, you know, 94 of
them.
This year
it's 74 are Chinese.
And that's because they made a huge
investment in science and STEM
research. They
They You know, they they put they poured
out a million engineers for
to to implement AI,
right?
Uh you know, they're they're doing the
right thing. We did that. Remember when
the Sputnik uh went over, the Sputnik
moment?
We made a huge investment in STEM, in
science and engineering, and and in
education.
>> What was a Sputnik moment?
>> Oh, okay, '57 when the Russians put a
satellite that went over the US over and
over again and we didn't took us years
to put up our own satellite because we
had fallen behind.
But we that investment we've been living
on
literally, you know, for the last 60
years.
And now the the Chinese have done that
and and they're going to be advanced and
they're going to be way beyond us.
Uh you know, I
this is
You asked me, okay? That's something I'm
I was I'm very very uh
disappointed in our country that we're
we're not In fact, we're just doing the
opposite. We're tearing apart science
right now with with the present
administration.
>> What are you scared of, Daniel?
>> Losing my wife. That's the most
the thing that comes to mind. And when I
was thinking about China and my
mother-in-law was a prepper.
And
>> being someone that's preparing for the
end of the world.
>> Prepared for the end of the world.
And we were in Egypt last year and got a
call that she had cancer and we were
there for 3 days and came home.
And I kept thinking I loved her dearly.
I'm like, you prepared for the wrong
thing.
You should have prepared for cancer.
Like I think every day we should be in
the same Alzheimer's prevention program
is a cancer prevention program. It's a
heart disease prevention program. It's a
diabetes prevention program. And I'm
like, she's prepared for the wrong
thing. The thing you really want to be
prepared for is disease, right? And I
know I'm going to die. I just want to be
a vital for as long as I can be and hope
is well, I have a say
in this.
Right? Cuz I know I can accelerate
my body's decline
or I can decelerate it. And I'm going to
choose to decelerate it.
Thank you. We're done.
Ask follow-up questions or revisit key timestamps.
The video features an in-depth conversation between the host, Dr. Daniel Amen, and Dr. Terry Sejnowski, discussing the impact of large language models like ChatGPT on brain health, memory, and cognitive development. The experts highlight concerns about reduced cognitive load and critical thinking, the risks of excessive use of technology for children, and the potential for emotional dependency on AI personas. They provide actionable advice on maintaining a healthy brain, emphasizing the importance of lifelong learning, physical exercise, proper nutrition, and conscious, meaningful interaction with technology to avoid cognitive decline.
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