This is not what they're telling us. We

can start to heal some of these chronic

lifestyle conditions that are so rampant

with tiny doses of this. It's like

opening a window of opportunity for

somebody to completely change their

life. Dr. Tina Moore is a distinguished

naturopathic physician

whose groundbreaking work is leading the

way in combating some of the biggest

diseases and medical conditions that our

modern world currently faces. Everyone's

saying that Ozempic is evil, this is the

worst thing ever, but a lot of people

are being overdosed for weight loss and

this leads to a very high risk for side

effects. But Ozempic done correctly has

all these other benefits that have

nothing to do with weight loss and they

are just mind-blowing. Healing and

reversing type 1 diabetes, Parkinson's

and Alzheimer's. We've got studies

showing really positive impacts on

depression and anxiety and potentially

reducing cancer risk. It shifts your gut

microbiome to a more favorable

microbiome and then my daughter's PCOS

symptoms reversed which is probably one

of the number one drivers of infertility

in young women. I mean, holy sh

and I've seen it with my patients and

I've seen it with myself cuz I lived

with chronic pain my whole life.

And I remember by the end of 2021

thinking, if this doesn't get better,

I think I'm going to kill myself.

But I started myself at a tiny little

dose and the destruction fell away.

Dr. Tina Moore, what would you scream to

the world right now? We are eating a

chemical storm of a food supply. Young

women are bathing in toxic chemicals

through their beauty habits. Microbiome

disruption from all the antibiotics. I

joke that humans are going extinct, but

I think it's really happening if we

don't right this ship. But there's

things we can do that are non-negotiable

that have nothing to do with drugs.

Your six pillars for a pain-free life.

Yes. First of all, I would

Congratulations Diary of a CEO gang,

we've made some progress. 63% of you

that listen to this podcast regularly

don't subscribe which is down from 69%.

Our goal is 50%. So if you've ever liked

any of the videos we've posted, if you

like this channel, can you do me a quick

favor and hit the subscribe button. It

helps this channel more than you know

and the bigger the channel gets, as

you've seen, the bigger the guest get.

Thank you and enjoy this episode.

Dr. Tina Moore.

Who are you by profession

and

what is the mission that you're on?

So I'm a naturopathic physician and a

chiropractor. I don't know if you have

naturopathic physicians here in the UK.

We are trained formally in a four-year

medical program and we take national

board exams, North American, I should

say.

And we are taught root cause medicine.

So the functional medicine community

basically appropriated our medicine many

years ago. If you've heard of functional

I'm you've had doctors on their

functional medicine practitioners.

And it's the idea that the body can heal

itself. We are looking to restore

homeostasis in the individual. So why

are things awry? I'm less interested in

someone's diagnosis as much as I am why

are they presenting with that symptom

picture? What's going on?

And I was mentored up by one of the

finest naturopathic physicians in our

profession over the past many decades

and he died of cancer in 2013 and I took

over his practice.

He was a force to be reckoned with. So I

carry that flag with me and he was a

truth teller and he was

often ostracized by our profession for

being ahead of the game and, you know,

being ahead of the story usually and I

learned so much from him about metabolic

health and how metabolic health was

really the root cause driver of so many

diseases, lifestyle induced diseases

that we're seeing in and on a worldwide

level. Can you give me just a bit of a

glimpse in it for someone that's never

heard the term naturopathic physician

before? Which which I guess means

naturopathic doctor. Mhm. Right.

What is the difference between like a

normal doctor and a naturopathic doctor?

So a traditional allopathic physician is

what you're going to be familiar with

with an MD. They're trained in a system

where algorithmically they are taught to

find disease processes and then they

have a standard care that they follow

which is to prescribe X, Y and Z Yeah.

for the standard of care and that's not

how they always were.

Naturopathic medicine was born out of

old-timey European MDs. So back in

Germany and, you know, long time ago

when we didn't have all the fancy lab

tests and we didn't have all the fancy

pharmaceuticals, we were treating people

to bolster their health, really. You

know, it's taking you as an individual,

finding out what makes you tick and then

how can we optimize your health overall?

Symptoms and illness falls away when you

treat the body, when you treat the

individual in front of you. So I don't

treat diseases, I treat people. That's

the difference. Whereas in allopathic

medicine, they are very obsessed with

the

diagnosis and then what pills do we

apply to that diagnosis?

Which is different than why is this

person presenting this way and what can

we do to help them along

the journey of

optimizing their health so the symptoms

fall away.

And you you said you took over a clinic

there. Yeah. What kind of patients do

you see in that practice? Did you see in

that practice and what was the sort of

variety of illness or disorder or

disease that you came across?

So his practice was predominantly

musculoskeletal medicine. So it was

chronic joint dysfunction and he did a

specialized type of medicine called

prolotherapy and regenerative injection

therapies. The modern version of that is

stem cells. You've probably heard of

stem cell injections. I'm sure everyone

has by this point. Platelet-rich plasma

is another one. And that's what he

specialized in, but it's not just about

shooting fancy substances into people's

joints. You have to get the person into

a healing state first. So you need them

optimized so that they want to heal. So

that means hormones, that means

nutrition, that means lifestyle. Those

things are far more critical to get

lined up than it is to start shooting

fancy substances into their joints. Even

if those substances come from their own

body. Even if we're sucking out their

own stem cells and we're sucking out

their own blood and we're using those.

It's far more important that you get the

person in an optimized state so that

they

want to heal. So I would I you know, I'd

ask patients, if you cut your fingertip

off or just sliced yourself terribly, do

you heal well? And if they said yes,

they were a wonderful candidate for

those types of injections. If they did

not, then they weren't because they

weren't in a good healing state at that

point. So my job was to get them in a

healing state and then to apply the

treatments. What is a healing state?

It's when you fall down and you don't

fall apart. It's when you get sick with

something and you get over it. It's when

you cut yourself and you heal readily

and you don't, you know, succumb to

terrible infections. And I think we've

ended up as a society

where the norm has become to be somewhat

immunocompromised. I think a lot of

people are walking around, not not you

younger folks, but at least in the US, a

lot of people are walking around in this

sort of semi-immunocompromised state.

Much of it is due to metabolic

dysfunction which is something he was

always drilling into me. What is

metabolic dysfunction? It is when your

metabolic health at its core is the

ability to take in the foods that you

eat and assimilate them properly. So if

you were to eat proteins and fats and

carbohydrates,

you would turn them into the fuel that

they need to be. You would turn them

into the proteins in your body that they

need to be.

When

that goes awry which is

almost 100% of US adults at this point

from what the data is showing,

things don't go so well and so what that

leads to, this metabolic dysfunctional

pattern leads to insulin resistance

which is essentially prediabetes

which is the long game into type 2

diabetes. And we've completely

normalized that process at least during

my lifetime. I've watched that happen.

I'm 50 years old so I've watched this

happen especially since I got into

medicine working for my mentor Dr. Rick

watching folks go down this pathway of

normalization into type 2 diabetes and

it's not until they get there that the

doctor says, "Oop, you have type 2

diabetes, we got to do something about

it. Here's your pills."

And there's

15 to 20 years of legwork that can be

done before that happens and that's

where I think naturopathic medicine

really shines and where preventative

functional medicine, all of us are in

the same camp. We're all doing the same

thing. We're really trying to just help

the patient in front of us, not so much

the disease process. We're trying to

make sure that the person's optimized so

that they can

become more resilient, so that their

immune system works properly, so that

the foods that they eat are assimilated

properly and they don't end up in a

cellular milieu of disaster. Is is there

like a fundamental belief that you have

about human beings, how we heal, how to

be healthy

um

and the body, I guess, that you think is

in contrast or conflict with the current

system? Like a set of fundamental

underlying beliefs cuz we all have like

a set of sunglasses on, our lens of how

we see the world.

Yes. And what I've obviously learned

from doing this podcast is everyone

seems to be wearing slightly different

lenses. Mhm. You know, as to their view

on health, the the health care system,

humans healing, society.

What are those sort of fundamental

underlying beliefs that you have? It's a

great question.

I think that in

traditional naturopathic medicine, the

purest would tell you that there's no

room for pharmaceuticals and that you

must only go with nature, the healing

power of nature, stoke the individual's

vitality. That's very important in

naturopathic medicine. We're looking at

the vitality of an individual. Some

would call that an aura. I think that's

a little too esoteric. It is

when you look at someone, are they

are they glowing vitality? Do they look

healthy? You can see it. I know you can

everyone can see it when you actually

point it out to people. Do they look

healthy or are they sort of walking

around in gray scale? Right?

And I think a lot of people these days

are unfortunately walking around in gray

scale cuz they've sort of

you know, we've all been listening to

the mainstream narrative and the food

supply is busted. This has been going on

for decades.

My mentor was talking about this decades

ago and nobody was listening and now

people I think are starting to get hip

to it because we've got the internet,

we've got podcasts like yours and mine

and where we're trying to get the, you

know, the information out. And it's the

inherent ability of the body to heal.

However, I do think there's a place for

pharmaceuticals and I have a license to

prescribe in the state of Oregon and I'm

not afraid to use it because in my mind

and the way that my mentor taught me is

somebody comes in and they're on this

many pharmaceuticals. I mean, I'm 50,

the average person my age is on five

different pharmaceuticals at this point

which is crazy to me and I don't know

what the stats are in the UK, but I

can't imagine they're tremendously

better. So, they come in on all these

drugs and their lifestyle is in somewhat

of shambles. And so my job is to

optimize lifestyle so that I can get

these down to the lowest or to nil.

Ideally, we could get them off, but if

they need a little something then great.

I was also taught by him to implement

longevity medicine which is hormones and

making sure that people are able to

maintain physiological levels of optimal

hormone function as we age which is

really important to aging well. And so

it's just kind of a mix of using the

best of nature and that science has to

offer and treating the person in front

of you. Of all the case studies that you

have in your mind, experience and in

your past, is there one that you are

most proud of? It was 2019.

My career was really taking off and my

mom kept telling me that she didn't feel

good.

And I was like, my mom is a rock. My

mom's My mom's like comes up to here on

me. I call her my little mama and she

just chugs along and I was like, oh,

she'll be fine. She's like, no, I really

don't feel good and I kept blowing her

off because I was too busy and I was on

planes all the time and traveling all

the time and I was never home. And my

mom came to visit me at my house and

she came out of the bathroom and she

said

she's like, I

like I can't hold my bowels. Like I I

can't. I'm so sick.

And so I immediately started testing her

and she had Crohn's disease and my

grandmother had died of Crohn's disease

and several people in her side of the

family had died of Crohn's disease

and I just hadn't put two and two

together that my mom may have had, but

she had all the symptoms. Like growing

up, she had all the symptoms and I just

never put it together.

And it was hitting her. It It rears its

ugly head when folks hit their elder

years, like in their 70s. They call it

you know, colitis of the elderly and

people basically get it and die. They

just [ __ ] themselves to death.

And so my mom was in it and I was like,

oh, no.

And I pulled out everything I had and I

have access to some incredible

regenerative

substances that, you know, most people

don't and I can use them off-label in

ways that

you know, in most people don't even

think to do and I threw everything I had

at her

because I knew if I had sent her into

the allopathic system, they were going

to do a colonoscopy on her and what that

does is they flush you out

before they do the colonoscopy and if I

if her flora were to get flushed out of

her gut at that point, I don't think she

would have come out of the hospital

because they end up getting secondary

infections. And so I I pulled her out of

it. I got her out of the really acute

phase and then I immediately referred

her to my colleague who is a brilliant

physician, naturopathic physician and I

was like, take over. I'm not I don't

want to manage my mom.

But I needed to get her I I I knew that

it was the skill set that I had in

particular that was going to pull her

out of that and so we did it and

she came to me one day after she was

better and she was stabilized and she

said, you saved my life. And at the time

I was

really bitching about my

half a million dollars of student loan

debt that was just compounding and

compounding and compounding and

I was really frustrated by the fact that

I couldn't get on top of it and I had at

that point spent like a hundred thousand

dollars paying off my loans and they

were still at the same level. I mean,

it's just criminal that system. And she

said, you saved my life. It was worth

every penny, you know. And then my

daughter turned around who had just gone

through a very difficult time herself

and she said, you saved my life too,

Mom, this year and I was like

well, if that was what it cost to gain

the knowledge that I gained to save my

daughter and my mother and then my dad

was like, you saved my life you bailed

me out many times and I was like, okay,

that's So, it was kind of um

it was just kind of ironic that was the

end of my big

clinical career, you know, when I had my

big brick and mortar with the high

volume patient base and all of that. I

still see patients, but not at that

level and so that was really

I was like, thank God I had the

knowledge and the tools and the know-how

to and the fearlessness to apply some of

the therapies that I applied the way I

did to In terms of before and after

what sort of picture of health would I

observe if I saw her on that day when

she walked out of the toilet versus you

know, after the

the variety of different therapies that

you applied?

Well, this is a good story because she

was super gray and super thin. My mom

has always been kind of, you know,

hippie and curvy and I mean, she's we're

built different. She's she's the more,

you know,

she's the curvy one and she was just

rail thin and gray and all of her hair

was falling out. I mean, she just I

can't believe I missed it. I can't

believe it went on that long that I

didn't see it and I I still carry guilt

to this day and I always apologize to

her for being too busy to

I can't believe I let my stress level

get so high that I didn't see it, you

know.

And then she ended up on a slew of

pharmaceuticals that were too expensive

to get in the United States, so she had

to get them from Canada. So, her

naturopathic physician is managing her.

So, she's getting medication, very

expensive medication from Canada

and she's doing okay.

And then in the last nine months, I put

her on the tiniest droplet of

semaglutide which is Ozempic.

And she is phenomenal. All of her joint

pain's gone. Her gut's completely

regulated and normalized. She is down on

a minimal dose of this medication that

she's getting from Canada. She's still

taking it, but it's a tiny dose. Her

cognition has improved significantly

because through this process she was

starting to get low-grade dementia

whether she realizes it or not. My

daughter and I were noticing it. We were

like, is Grandma okay?

And so

when people come at me for talking about

microdosing Ozempic, I will not back

down because my mom is solid and it's

the tiniest amount and she even said to

me just the other day before I was

coming on the show. I was telling her I

was stressed. I was trying to get ready

for the trip, you know, overseas and she

said, you know, I was so stressed out

before you put me on semaglutide because

my dad's health is very poor and she

said I was so stressed that I

really felt like it was going to do me

in. Like I was at capacity and you put

me on the semaglutide and all of the

anxiety and stress just dropped away.

And I was like that's cuz it's

calming to neuroinflammation which is

secondary to chronic gastrointestinal

diseases. When the gut is inflamed, the

brain's inflamed. So, she was dealing

with all this chronic brain

inflammation, all this gut inflammation

and she's on this tiny little dose of

Ozempic and she's

very solid and she's her color's back.

She's filled in again. She's curvy

again. She's eating normally. She

doesn't I mean, she couldn't eat hardly

anything ever for years and so now she's

back to eating very normally. She's

still got to watch what she eats, but

you know, it's not a free-for-all, but

she is she's back. The other I guess

glaringly obvious case study for your

work, but also I think many of the

things we're going to talk about like

microdosing Ozempic is you.

Yeah. Because as I read through your

story from your childhood years through

your teenage years and even in

university um and then even later into

your career and I guess also now cuz you

mentioned that you you still deal with

chronic pain

you are your own case study. I am.

Can you give me a view of of the

struggles you've been through in terms

of your health um and really where that

started. What was the sort of first

first instance where you experienced the

pain, the trauma, etc., etc.?

So, I always had stomach aches.

Always. Since I was a child, always and

was hit with really pretty severe

anxiety. I didn't know what it was at

the time, but it was anxiety and I

started getting chronic pain in my

teenage years and I out of nowhere when

I was about 15, the lights went out on

me. I just became extremely suicidal and

depressed out of nowhere. I mean, it was

like somebody just switched a lever. I

had moved to Oregon from Southern

California. I do believe that the lack

of light

was massive. I think that people really

I'm really starting to appreciate it's

taken me all these decades, but light

deficiency is a huge issue that we're

not no one's talking about. A few people

are, but You're talking about like

vitamin D production as well right there

cuz there's

Oh, that was huge. So, that took years.

You know, nobody was talking about that.

It was not until decades later I was

sitting in naturopathic medicine school.

I was in college and

um I think I was in year three of that

program and this doctor, Dr. Alex

Vasquez came to lecture at grand rounds

and he started talking about vitamin D

and sunlight deficiency and I had been

kind of low-grade looking into sunlight

deficiency because it turns out the

hospitals of yore really would optimize

sunlight and they would have sun

porches. I don't know if you've seen the

photos. They would roll all the kids out

and all of the convalescing ill people

out. I mean, that's how people survived

the 1918 flu was the ones who got

sunlight and the ones who were able to

go to these hospitals and they would

build the hospitals to optimize light

exposure inside the ward cuz they knew

it kept the bacteria counts down and I

mean, even if they didn't know what

bacteria was or what was happening, they

knew that when sunlight penetrated,

people were you know, healthier and

things were cleaner and infections

didn't seem to spread and so I hit my

20s and long story short, I was rocking

psoriatic arthritis for decades before I

ever figured it out and it really

culminated for me

I went through a lot of chronic pain. I

went through a lot of misery. I went

through a lot of autoimmune issues and

then I got everything dialed in. I

thought I had it handled. Interestingly,

autoimmune disease will flare and will

recede and flare and recede and it's

kind of on cue. Like you'll see it

around 10 to 11 years old, especially

with things like Crohn's disease, you'll

see these little glimmers pop up for

kids and then it goes away.

And then you'll see them present in

their teenage years and often they'll

present with you know, mental emotional

issues and not so much the

gastrointestinal issues, but it's the

same process going on in the body. And

then it'll go away and then it might

flare again postpartum because of that

big hormone surge that happens with

childbirth and then it'll go away and

then it'll come back with a vengeance in

menopause as the hormones again shift

majorly and that's what was happening

for me and then all of the stress of

pushing back against the narrative

really caught up with me and I was I

nothing that I knew to do was working.

So the whole protocol I put my mother

through was not working for me. Nothing

was touching it and that is how I came

to start studying GLP-1 agonists. I

started I was researching anything that

would calm neural inflammation because

at the end of the day

diseases down here are coming from here.

And when the brain's on fire and the

brain's inflamed the immune system gets

sent completely sideways and the

downstream processes culminate in

autoimmune disease, pain, hormonal

disruption, you name it. And so

I

that's how I ended up I literally put

into Google GLP-1 and neural

inflammation and

all these studies showed up and that's

what got me going. Two questions there.

So GLP-1 is Ozempic? So it's yes, it's

the peptide that the body makes

naturally.

We make it in the brain and we make it

in the gut. But if somebody's had a life

of chronic gut inflammation, I don't

think they're making it so well in the

gut. And

Ozempic is just a

it's several versions down in the

generational line of these

peptides called incretins. They're um

they're a whole family that started way

back 20 some years ago and they've just

gotten a little bit nicer with less side

effects and longer half-life as we go

along the journey. So the last decent

one was liraglutide, although compliance

was low because it made people feel

really terrible and they had to inject

it too frequently. I think it was daily

or I think that's how it is still. And

then semaglutide is a newer generation,

tirzepatide is a newer generation and so

they're they're just getting a little

more potent and I don't mean potent in a

pharmaceutical way. I mean they're

starting to realize how these work and

they're they're getting craftier with

not only keeping them in the body for

the time that they need. So the

half-life gets longer, but they're

finding in the suite of signaling

peptide hormones that are involved with

appetite and with metabolic health and

insulin secretion and insulin

sensitivity, they're finding better and

better ways to combine these to get

optimal function with the least amount

of side effects. Okay. And at that

moment in your life where you started

Googling GLP-1 and inflammation etc.

If I was a fly on the wall

in your life at that moment

what would I've what would I've seen?

What was the sort of picture

of

desperation or

you know? So 2021 I spent most of that

year on my back cuz I was in so much

pain. It was crazy. And my husband when

he met me, he met me in 2019 and we got

married in 2020.

And I told him I had chronic pain and I

told him I had a funny immune system,

but he had never seen it. Like he'd

never seen it full force and he got to

see it that year. He was like, wow, so

this is what chronic pain looks like. I

mean it's it was devastating and my

spine was fusing and I'm active. Like I

do Pilates and I dance a lot and I hula

hoop and I roller skate and I lift

weights and I'm you know, I'm moving and

shaking. I was not moving and shaking in

2021. I was 2021 I was flat on my back

on the couch and I remember by the end

of 2021 thinking

if this doesn't get better

I think I'm going to kill myself. Like I

couldn't do it anymore. Like I just

couldn't live with that level of pain

and my spine was fusing and I could feel

it and I kept trying to tell everyone

something is wrong.

And my chiropractor friends were great,

but they knew musculoskeletal medicine

and my naturopathic friends were great,

but they knew systemic medicine and I I

needed me. I needed my brain on the

case. Like someone who had both, right?

And I just couldn't get on top of it and

then finally I I don't know how or why I

I went kind of into the story. Oh, I

know what it was. I broke out with

psoriasis. I broke out with psoriasis

all over my scalp. And I was like, oh,

this is what this is. This is psoriatic

arthritis, which turns out to be one of

the most painful musculoskeletal

autoimmune conditions you can have. It

it's worse than rheumatoid arthritis on

the pain scale from what the studies

show. So I was like, okay, now that I

know what I'm dealing with, what can I

do? So I started pulling out all the

stops and all the things I knew to do,

low-dose naltrexone, exosomes, you name

it. I was doing everything.

It really wasn't bringing it down or it

would work for a minute and it would it

would it would wear off. And so I was

getting desperate and my pod I have a

podcast and my podcast producer said,

you got to do an episode on Ozempic. And

I was like, I don't I don't like talking

about weight loss. I really don't like

talking about weight loss. It people get

so emotionally triggered and it's a big

topic and it's nuanced and

it's not as simple as people want to

make it be. And in my functional

medicine world, people want to make it

so simplistic, just exercise more and

eat less and take these supplements and

it'll go carnivore and it'll all go

away. It's not that simple. There's

genetic components, there's brain

components, there's epigenetic

components and

it was like the Pandora's Box I didn't

want to open.

And so finally I was like, okay, fine.

I'm going to start researching these and

I was sitting I was laying on the couch

on my back.

And it's 2023 at this point, but I'm

still having to take frequent breaks,

right? On my back. So I'd go exercise

and I'd have to lay down for 3 hours. So

I'm Googling and I look up GLP-1 and

neural inflammation cuz I always start

there. I always start with pain,

neuroinflammation

and immune activation. I always want to

know what any substance does in those

cuz that's my world, right? Cuz that's

what I did in clinical practice. And I

Googled that and my husband's in the

kitchen and I was like

holy [ __ ] And I turned the phone around

and I was like, look at this. And he's

like, I don't know what that means,

babe. And I was like this is not what

they're telling us. Like this is not

what cuz that was at the height of

mainstream media and all the clickbait

headlines and you know, mom is

overdosing on Ozempic and people's

stomachs are paralyzed forever and I was

like so then I started of course looking

at all that. Like is that for real? Like

are they really getting gastroparesis

forever? No. So I start going into all

the data and I just that was it. It was

like the rabbit hole and it that was May

of 2023 and I've been knee-deep in it

ever since just consumed by any and all

informa and then of course everybody

start I started doing podcast about it

on my show and everyone's sending me all

the information and hundreds of people

are reaching out to me telling me these

really profound stories and changes in

their health that have nothing to do

with weight loss or diabetes and so

that was it. I was like, I got I got bit

by some kind of um well, you know, I

don't like propaganda.

I don't like when I hear everybody

saying the same thing. It makes me

suspicious, you know, when everyone's

running in one direction screaming this

is evil. This is this is this is you

know, the worst thing ever. I was like I

don't know this has been around for 20

some years, not semaglutide, but this

version of medication, this family of

medication and so I don't know. I was

like, I'm not buying this. I'm going to

find out what the truth is. And so I

called every doctor I knew that might

use it. I called every pharmacist I knew

that might use it.

Nobody was seeing any of these horrific

side effects. Like the stories you were

seeing on the media currently, what was

that? Summer That was really it it came

to like full height summer of 2023. I

think that was when everybody was losing

their minds about it. The minute they

started talking about weight loss

people started losing their minds about

it, which I find very interesting. And

what I was finding in the literature was

not at all adding up to what

I was hearing. And then there were all

of these other benefits that

were just mind-blowing. You know,

benefits on healing and reversing type 1

diabetes. Healing and reversing

neurocognitive conditions like

Parkinson's and Alzheimer's.

Efficacy with alcohol cessation. People

who were you know, alcohol abuse

syndrome, using it for that.

People who also had the this type of

it's HLA-B27. It's a genetic propensity

towards these

um

spondyloarthritises like psoriatic

arthritis, rheumatoid arthritis, those

kinds of things. Having showing efficacy

for that. And as I started speaking out

about it, I was getting messages back

from people

telling me their stories. Hundreds and

hundreds of people telling me their

stories and I and then seeing what was

happening with my patients. So I started

applying it to everyone I was treating

for different reasons. At different

doses. Very tiny doses though, very

little bits. And just seeing really

profound changes in people.

And I

it's not what we're hearing. And I don't

think that the way also that it's being

done in the standard model is

ideal for everyone. I think a lot of

people are being dosed too high, too

fast and I think a lot of people are

being overdosed cuz at the end of the

day it's a hormone. It's a peptide

signaling hormone and so people are

being cranked up on doses very quickly.

There's a 16-week escalation and they go

from this amount to this amount very

quickly and in the journey, many people

are reporting horrific gastrointestinal

side effects, which are real. But it's

not the peptide's fault. It's the it's a

peptide at the end of the day as well,

which is I can explain what that is.

Yeah, if you had to explain what Ozempic

is or what go over your, you know, this

this compound is just to a 10-year-old.

Yeah, okay. How would you explain it?

So, you eat amino acids, you eat protein

and it breaks down into amino acids.

Yeah. And amino acids link up with

peptide bonds into chains called

peptides. And then peptides What's a

peptide bond? Uh, it's just a simplistic

bond that binds two amino acids

together. So, it can be broken pretty

readily with different enzymes. And

that's in my body, the peptide bond is

in my body. Yeah, so your body has all

these enzymes present and the amino

acids link up very simplistically into

different chains. And then those chains

of amino acids are called peptides. And

peptides link up to form proteins and

your body is made of proteins, your

whole body. All of your tissue is made

out of proteins. And your cellular

receptors are made out of proteins,

everything's made out of proteins. So,

if you go backwards, those smaller

versions are the amino acids, I'm sorry,

or peptides and the smaller versions of

that yet are the amino acids.

Mhm. So, we eat protein, we break it

down into amino acids and we reconstruct

it into more protein. Mhm.

And so, peptides are these chains of

amino acids that we've got all different

types of therapeutic peptides and they

insert themselves where they need to go

to do what they need to do. Mhm.

So, that's it at the end of the day. And

what so, what's a Zempic in that? Is is

Zempic is a peptide?

It's a peptide. And it's made in our L

cells of our gut, which line from the

most proximal to the distal small

intestine and it

secrete these cells secrete GLP-1 in the

presence of glucose, which is sugar when

we eat sugary foods or

food well, all carbohydrates break down

into glucose. So, whenever we eat

glucose and they respond actually when a

bolus of food so, the mechanism of a

blob of food going through our guts

actually gets these cells to trigger.

Mhm.

However, I have tested thousands of

people's guts in my clinical practice in

my clinical lifetime and people's guts

are a mess. Most people have compromised

digestion. So, I don't think their L

cells are working optimally in many

cases.

And we also have literature, good solid

science to show that those who are

suffering with obesity, type 2 diabetes

and fatty liver and that whole metabolic

syndrome,

you know, groupage, those folks are

GLP-1 deficient. So, when I take a

Zempic, it's causing my

gut, basically, my body to release

GLP-1. No, it is the GLP-1. Oh, it is

the GLP-1. Yep, so we're not causing the

gut to do anything, we are mimicking the

actual peptide. Ah, okay, so it's got

the same sort of

atomic structure. Is it GLP-1? So, my

body thinks it's GLP-1. I guess it is

GLP-1 as far as things are concerned.

And then the GLP-1 is doing what to me?

Well, so it's semaglutide, for instance,

is bioidentical to the GLP-1 that our

body secretes. So, it's the same except

it's been tweaked with a little bit,

they've added some lipids to it to make

the half-life longer. So, it lasts

longer. So, normally GLP-1 would be

secreted from our cells, it's also

secreted from our brain, which we got to

get into cuz that's where I got really

excited. It's secreted from our body and

it's broken down very quickly. And so,

these

newer versions of these incretin

hormones or incretin peptides are broken

down at a slower pace. Okay, and then

what does GLP-1 do?

It does all kinds of cool things.

So, it most notably what it's known for

is to decrease appetite. Mhm. And that

happens centrally in the brain. Yeah. It

slows gastric motility, so it slows

things down so you feel fuller for

longer. That's at higher doses, that

doesn't always need to happen. And

that is what it is known for and it also

has induction of it it plays with the

cells of your pancreas and it gets them

to secrete insulin at the right time.

And so,

most folks are walking around in some

degree of insulin resistance as they age

and that is the beginning glimmers of

type 2 diabetes. And so, GLP-1's help

that process, it helps sensitize the

cells to the insulin and it helps

secrete the insulin when needed.

And when you were struggling

in 2023, Yeah.

you started taking a Zempic,

semaglutide,

one of these brands. Yeah.

What impact did it have on you?

So, I got a compounded version because I

thought that the starting dose let's

back up. The brand name, the

prescription that most people are

familiar with are these little

pre-filled pens. Yeah. And the pens only

come in certain doses. You can't control

the dosage. You start at the lowest dose

that they offer and then you have to

escalate from there. Or if your doctor's

cool, they won't make you escalate too

much, but either way, you don't get to

go lower than the dose that it starts

and it starts at 0.25 mg.

I thought that that was way too high,

especially for someone like myself. I'm

very metabolically optimized. I have

good muscle mass, I have very good bone

density, I have my labs look beautiful,

I'm hormonally optimized, I'm on

bioidentical hormone replacement, I'm

very active, I exercise often, my sleep

is good. And I thought my thinking was,

I wonder if

some of us are actually a little GLP-1

deficient from whether a life of

not because we have obesity, diabetes

and fatty liver,

there's different reasons why those

folks would be deficient. Insulin at

high levels itself will actually induce

some GLP-1 deficiency, it'll it'll

decrease in GLP-1 signaling. My thinking

was, I wonder if folks are just

genetically or maybe we got ourselves

there through chronic illness, whatever

it may be, I wonder if there's a little

bit of a deficiency. What if I

supplement this peptide like I would a

hormone, which the way I do that is I

give people the lowest dose necessary to

achieve a physiologic impact that's

favorable and then I cap it. So, if you

need a little bit of thyroid, the

standard model would have you take,

well, you know, the algorithm says you

have hypothyroidism, so we're going to

give you this much and we're going to

give you this exact drug. In my world,

we compound what we need, maybe you need

a little more T3 than T4, maybe you need

a tiny dose, maybe we titrate you up

until you start getting a little

symptomatic and we're like, oh, let's

back it down a little. So, my thinking

was to use it that way. So, I asked

everyone I knew, are you using this for

anything other than appetite suppression

or weight loss or diabetes? And they all

said no, nobody really was. None of my

colleagues were anyway.

And they were all starting at a dose

that I still thought was too high. So, I

started myself at a tiny little dose

and my first impact was brain clarity.

Within days, my brain cleared. I can't

even explain it. Um,

brain fog was definitely starting to

happen. I think it was the psoriatic

arthritis and I think it was the I think

it was post-COVID, you know, I think our

brains all got hit pretty hard by that

and I think it was chronic stress and I

think it was menopause and I was sort of

in this

I'm a high-functioning kind of boss babe

and I couldn't get my work done and my

team was going crazy cuz I couldn't

remember what I told them and you know,

they're calling me and they're like, we

already did this, we already had this

conversation, what is wrong with you?

So, I was like, damn it, this isn't

going to work for me. I can't be rolling

the way I'm rolling and trying to run

all my businesses and have brain fog

like this. So, that was the first thing

I noticed was clarity of thought, brain

fog went away, anxiety immediately

dropped, which I didn't even realize I

had. It's just a calmness took over me,

which was so amazing. And within

two weeks, my pain was down

significantly, significantly. And what I

noticed was everything was starting to

move and pop again. So, I was getting

mobility back. And by week two, I wanted

to move again. So, this version of me

that just wanted to like go do my

workout, go to my work and then lay down

on my back,

I wasn't that doing that anymore and I

immediately like signed back up for

Pilates and I found myself dancing and

hula hooping around the house again and

I found myself just being much more

active. And slowly but surely,

the destruction sort of fell away cuz I

had been in a pretty destructive immune

process for a couple years there and it

just has it's taken me I think it's been

almost a year now

and it's just slowly but surely dropped

away. I also noticed a little bit of

weight loss, which I had gained some

weight over the past couple years. I

think it was chronic stress was doing a

number on my metabolism. And you know,

you hit that 50-year-old mark and things

get tough. So, I had some weight loss

fall away. I got right back down to my

fighting weight. I'm like literally the

size I was in 2019 going into all of

this.

And so, I quickly started putting people

on it and very similar

responses.

Um, all of them had a little bit of

fluff, but nobody was on it for weight

loss. Everyone had a little bit of

weight,

fell right off, got back down to a good

weight. My mom, I was particularly

concerned about cuz I didn't want her to

waste away again. I didn't want her

vomiting. I didn't want her having any

gastrointestinal symptoms. I wanted all

of those to resolve. It shifts your gut

microbiome to a more favorable

microbiome if you do it right. And so,

and we have the data on that. So, I was

very slow and cautious with her. I don't

want her losing any muscle mass and

everybody just had these profound

impacts. My daughter's

skin cystic acne. I mean,

a decade of severe cystic acne to the

point where she did not enjoy her

teenage years and she was suicidal from

it. I mean, just hiding behind her hair

for for years.

Her skin I remember seeing her after

three weeks on it and I was like, your

skin is porcelain, what happened? All of

her PCOS symptoms reversed.

Um, my husband didn't want to drink

anymore. The guy is a known alcoholic.

He was like, not interested in alcohol.

His blood pressure regulated out. I

mean, just all of these little things

started happening and I started seeing

similar

effects in my patients.

And then I

at the same time I was posting about it

and talking about it on my podcast and

people were messaging me telling me

these profound stories. They were like,

I went on it for weight loss or I went

on it for metabolic dysfunction or our 2

diabetes, but here's all the other

things that started happening. And then

people started telling me they were

getting pregnant on it. And you know,

when they had been infertile and gone

through rounds of IVF that were not

working and just all of these amazing

stories. And so of course I keep I have

to research that and do more information

on that. And it's just been

I've just been unwinding. I I feel like

I'm unwinding a story that isn't being

told.

So, what is that story?

To summarize, what is that story that's

not being told that you've come to

believe?

These peptides are healing. They are

anti-inflammatory and they are

regenerative. And they have a profound

impact on our immune system in a

positive way.

And they don't just cover up and mask

the insulin resistance and the metabolic

dysfunction that leads to type 2

diabetes. They actually heal it.

How do you know that?

Well, interestingly, as this year has

gone on, more and more studies have come

out and we're starting to see it. So

many of the hypotheses I had about it

are starting to show themselves in good

clinical data, in good studies. And I've

seen it with my patients and I've seen

it with myself. So I am now able to go

off of it. At first I could only go off

of it for a short amount of time and my

psoriasis would come back. That was the

first symptoms. I would start getting

skin issues and I usually get it around

my scalp line.

Little itchies. That

would come back within 7 to 10 days. I

am now able to go a month without it and

absolutely no symptoms. And the second I

start to get brain fog or a little bit

of pain,

I go back on. I cycle it like I would

any other hormone. I don't know if

you've had any guests on talking about

hormones, but they're done best when you

cycle them because receptors get

saturated. And when you saturate a

receptor with a hormone or after a while

the cell will stop listening.

And so you don't want to just keep

flooding a cell or a body with a

hormone. You want to take it away and

let those receptors pop back up. And so

I think done correctly and done in an

elegant way that's just reasonable,

clinically reasonable,

I think that we can actually start to

heal some of these chronic lifestyle

diseases that are so rampant.

And it makes me wonder if we would need

less and less and less of the common

pharmaceuticals that are being handed

out like candy. The lifelong

pharmaceuticals. People go on statin

drugs or they go on blood pressure

medications and no one says boo. They're

on it for life. Oh, here's your

metformin for your type 2 diabetes.

You're on it for life.

I think done correctly and also the

neuroregenerative process that these

induce in the brain. They actually

regenerate neurons.

Neuroplasticity is this concept where

when the brain when you do something

enough, your brain will hardwire into

that. And so any habit, good or bad,

that you consistently do or any thought

process you consistently have, if you're

chronically depressed or you're

chronically negative or you're you know,

I mean you know this. You're you you're

self-optimizing yourself all the time

and growing and trying to grow and be

better, you're plasticizing your brain

and hardwiring that circuitry. So it's

getting easier for you and you continue

to seek knowledge.

These peptides offer people a window of

opportunity of not only giving them the

onus of control back cuz there are some

mechanisms in the brain and the

dopaminergic pathways that are giving

people the

they're back in the driver's seat.

They're back in control of what they're

doing, but it's also inducing this

neuroplasticity. So if they are to

implement really positive lifestyle

habits during the period of time that

they're on it,

they

will hardwire that into their brain. So

it's like opening a window of

opportunity for somebody to completely

change their life.

You mentioned some studies though that

have really supported your thesis that a

Zempic is more than just a weight loss

drug and that it has these other sort of

regenerative properties and these

healing properties. What are some of the

studies? You've got some something in

front of you there that you brought with

you. What are some of these studies that

highlight this in your view?

Well, so there's one study in particular

that I don't have the title of it

written down where they looked at all of

the data on all of the GLP-1 agonists

that are out there, the different

versions that I mentioned. And they went

back through all of the studies and they

looked at it system by system by system.

And I gave your team a link to that. And

what they found is, I mean going from

tip to toe, neuroregeneration and

anti-inflammation in the brain.

They showed

improvements in cardiovascular tissue.

We just had a study come out at the end

of 2023 called the select trial. It was

a big one. Yes, it was sponsored by Novo

Nordisk who's the manufacturer of

semaglutide of of I should say of a

Zempic. And so people say, oh, don't

believe those studies. It was a

well-done study. It looked at

individuals in their 40s who were

overweight but did not have type 2

diabetes and it showed a 20% reduction

in severe cardiovascular events. So

stroke and heart attack and

and others. And so then people argued

once that came out and said, oh, well,

that poof, you know, Novo Nordisk did it

and that would happen if people lost

weight anyway, right? You'd you'd have

improvements in cardiovascular disease.

Well, they just looked at the data again

and realized that those benefits were

independent of weight loss. Whether

people lost weight or not, they still

had significant improvement in

cardiovascular outcomes, which there's

just nothing we don't have anything out

there that does that. I found data

showing regeneration of pancreatic

tissue, beta cells in type 1 diabetics

if given early enough. So if a person is

the

type 1 diabetes is an autoimmune

condition where the pancreas becomes

destroyed by the immune system. It's

different than type 2.

We don't have anything to help those

people. It used to be called juvenile

diabetes and then type 2 was adult

onset, but now kids, many many children

are dealing with type 2. So it's a big

mishmash, but they're very two different

processes. They shouldn't even have the

same name.

Anyway, done early um

reversal of that pancreatic damage to

the point where people didn't need to go

on insulin and were able to have

pancreatic healing. We don't have

anything that does that except stem

cells.

They

at the end of 2023 they had to stop the

flow trial because this was a chronic

kidney disease trial. Um

They had to stop it because the control

group they needed to be able to

ethically give the control group the

substance because it was so effective.

It was so effective at reversing chronic

kidney disease and kidney failure that

they needed to be able to offer it to

the control group ethically and not let

them continue on their journey of kidney

damage. So we've got this mishmash of

studies and then they've done little

studies here and there looking at muscle

for instance. It's regenerative to

muscle. It's regenerative to bone. It's

regenerative to our joints. Some of this

is in mice, some of it's in humans.

It's regenerative to the

testes and to sperm production and

motility. When you say regenerative to

say muscle, when people talk about a

Zempic, one of the big concerns is that

you lose a lot of muscle.

Right.

It's not true. I mean, it is true. I

should let me let me Okay. Let me

rephrase that.

Any

dietary intervention or bariatric

surgery that induces a severe caloric

restriction will lead to about 20 to 35%

muscle mass or I should say lean mass

loss. So this is a little bit of a

nuanced conversation. If you basically

put somebody into a self-starvation

mode, they will lose 20 to 35% of their

lean mass.

Lean mass is all the soft tissue in your

body. So that could be your tendons and

your ligaments and your brain and they

they clump it all into one and they're

looking at that and saying it's all

muscle. Muscle is a percentage of that.

Muscle isn't all

of your lean mass, right? And so that

kind of makes the thing this the studies

look bad there, I think. The other thing

that they don't consider in that is

pathologic muscle due to metabolic

dysfunction will be

marbled with fat. What does that mean,

sorry?

Well, it's like uh foie gras. When you

induce metabolic dysfunction in an

animal, which is what they do in

feedlots for cows often and they do it

to geese to get their liver fatty, you

will end up with this fatty infiltrate

in the muscle. So the muscle goes from

being this lovely striated linear

beautiful pattern to marbled with with

fat.

Mhm.

And that fatty infiltrate becomes very

pathologic to the muscle and it puts the

muscle itself into an insulin resistant

state. So once the marbling occurs in

the muscle, it's sort of a chicken and

egg downhill situation for the muscle.

And I do believe very strongly, and I've

been preaching this for decades, that

once that process starts, and it most

often starts in the thighs. You've

probably seen the pictures of the

cross-section of like this is an

80-year-old triathlete and his muscle

looks really beautiful and linear.

And then here's, you know, the average

80-year-old and it's really marbled and

the bone loss is significant and the

fatty layer on the outside is thicker.

But what's most important in that photo

is the marbling of the muscle. We don't

want marbled muscle. That's the

beginning of the end. You also end up

with fatty liver and you end up with

fatty pancreas when you're in this

metabolic dysfunction state, this

downhill journey that culminates in type

2 diabetes.

And so one of the first things that

happens when metabolic health improves,

whether this is through dietary

interventions, lifestyle, strength

training, you name it, is that fatty

infiltrate starts to dissolve.

These GLP-1 agonists

induce that process of the fat

dissolving. And so I think that's part

of the lean mass loss that they're

measuring. They're just measuring it as

lean mass loss, but we're also

decreasing muscle size

because we're having the fatty

infiltrate start to burn itself up.

GLP-1s have also been shown to perfuse

the muscle with angiogenesis so we get a

vascular supply so that more amino acids

are available to the muscle. So when

they looked at aging muscle in a human

and they gave them GLP-1 agonists, their

muscle became healthier and less

pathological because it started to

actually get better blood supply and be

infused with the amino acids they were

eating in the form of protein. So, it's

And then there's pathways that are

impacted as well that are inducing

muscle protein synthesis. So, GLP-1s

actually induce muscle protein

synthesis. They don't cause muscle

wasting. It's the caloric restriction

that's causing the wasting.

And they're measuring it somewhat

aberrantly. Does that make sense? That's

That's the story I'm trying to weave

here. Yeah, so but how how do I how can

I avoid the caloric restriction if I'm

taking the GLP-1 agonist like

semaglutide or Ozempic? You don't dose

it too high. So, you don't crush the

appetite. So, the whole goal is to keep

people at a dose where they still have

an appetite. You don't have to crush

their appetite with it. The way it's

being dosed traditionally is they're

ramping it up really fast and they're

just devastating people's appetite with

it. And so, people go from hungry and

starving to I don't want to eat anything

and so, they don't and then they often

will eat less healthy version I'm sorry,

they'll eat less volume of a poor of a

poor diet. So, they will continue to eat

junk food only less of it. They will

continue to eat the crappy foods they're

used to eating only less of it. And I've

heard Johann Hari on your show talk

about this and he beautiful book that he

wrote, his magic pill book. He talks

about that. He found himself about 5 or

6 months in and he was still just eating

the same crap. He was just eating less

of it. And what needs to happen when

anybody's on this at any dose is they

need to be protecting their muscle with

all their might. They need to be

strength training and they need to be

prioritizing their protein macros. Like

those are the two non-negotiables. I

don't think doctors are always talking

about that and I don't think patients

are compliant with that. If I start

microdosing there, what you know, won't

I see less of the reward? I see less of

the cost, but I won't I won't I not also

get less of the reward, the the positive

upsides that you've described? Not if

you're doing all the other lifestyle

things. So, like I said, it opens this

window of opportunity where people feel

much more in control because there's

impacts on the brain that allow people

to be much more in control of their

choices and of their thought processes

and of their even of their obsessions.

It's very interesting how it works. And

so, people are able to make better

choices and I think given

that window of opportunity and

introducing these lifestyle

interventions, they're going to be much

more open to it. So, we get them

exercising. We get them eating better.

We get them doing all the things you

know, we get them optimizing their

sleep. We get them going on walks and

meditating and

mitigating their stress. All of those

things are going to improve their

metabolic health. So, it's a two-pronged

approach and we don't have to crank the

dose. We can do this slow and low and

some people may need more and some

people may need less, but the point is

is the way it's being done traditionally

where it's like you get your scripts and

you walk out of your office and you

don't get any counseling, you don't get

any support. This is where people are

falling into, I believe, the terrible

pits of despair. So, this is where the

we're seeing the problems and it can be

done differently where we're doing a

holistic comprehensive approach with the

patient.

I was reading a 2024 study by Lindsey

Wang that found diabetic patients taking

Ozempic with 50% less likely to develop

bowel cancer compared to those on

insulin.

What does this say and highlight about

Ozempic's role in staving off cancer?

Well, that's an interesting study

because insulin is pro-grow.

So, insulin is also a signaling peptide

hormone very much like GLP-1 and it is

pro-grow when you give it to someone.

So, someone being on insulin, I believe,

will inherently

potentially make them more vulnerable to

cancer. I don't want to say certainly

because I don't want to scare everybody

because there's a lot of people out

there on insulin, but it is a pro-grow

hormone. Now, it's pro-grow in that we

get surges of it after we work out,

which is awesome. We want that, right?

We want that anabolic response, but in

your average person who's not working

out and who's not really using their

insulin the way they need to, they're

already swimming in it due to insulin

resistance and now they're taking

insulin cuz their pancreas is pooped

out. That's a mess. That's a soup of of

things we don't necessarily want

happening growing in the body. And so,

that study looked at insulin versus

GLP-1s. It's not entirely fair cuz it's

not a it's not a true control group, but

they there are other

data sets coming out that haven't been

published yet showing really good

really hopeful and positive impacts on

potentially reducing cancer risk. And

they're correlative, not causative, so

we can't put our finger on it and say

these these these reduce cancer, but

they looked at a you know, over a

million people that were type 2

diabetics that were on semaglutide and

they found a significant reduction in

different types of cancer that are

obesity related in comparison to the

folks who were not taking GLP-1s. And

those were the

cancers you don't want, the ovarian, the

pancreatic, the colon, the types of

cancers that are you know, you don't

come back from readily. And so,

that's very exciting. It's not getting a

lot of play and it's really really new

information, so I'm excited just to

watch it, but it makes sense to me

because these sit on your immune cells

as well. There's GLP-1 receptors

throughout our entire body. That's why

we're getting the impacts throughout the

entire body and I think that the impact

that it's having on the

overall immunologic milieu of an

individual

is potentially very anti-cancer.

I mean, that study that you cited there,

I know nothing about um Ozempic and

GLP-1s really, but in my even in my sort

of, you know,

chimp brain, I go, yeah, cuz if they

lose weight, they're less likely to get

cancer. Right. No, that's totally fair

and I think it's both because the way

that these are working mechanistically

in the body and many of the studies that

I've looked at are showing results

independent of weight loss. Even if they

don't lose weight, then their cancer

risk reduces. Well, they're the healing

and regenerative and anti-inflammatory

impacts are there regardless of weight

loss or not. And then you add in weight

loss and you add in insulin sensitivity,

you add in this this healing of the

metabolic dysfunction and you're going

to significantly reduce risk for

everything as well. I mean, that's a

really good point actually cuz

if has that has anyone done a study

where they give someone Ozempic and even

if they don't lose weight, inflammation

goes down? Well, that's what the SELECT

study this trial showed. That that

cardiovascular trial I just shared with

you, they just re-looked at that

information and realized that even

independent of weight cuz that was the

big argument everyone had is, well, of

course the cardiovascular benefits will

stay or will improve because they're

losing weight, but they found that even

in those who didn't lose weight, they

still had really good cardiovascular

outcomes. So, yes, it that's what that's

what we're starting to see and so, I

think they need to start looking at

these things more readily, but they

weren't, right? They were just looking

at like, here's morbidly obese people

and here's type 2 diabetics and we're

going to crank up the doses and we're

going to see what we see, but we're

starting to get longitudinal data now.

So, that

cancer one for instance was looking at

patient records going way back. And so,

they had over a million

you know, people in there that they're

Again, it's correlative, it's not

causative, but it's showing trends. It's

starting to show positive trends and so,

I think that's what we have to look at

and we have to start to

flesh that out. What about mental

health, things like depression?

Um and sort of anxiety and these kinds

of things.

You maybe have heard that these are

inducing suicidal ideation and people

are,

you know, getting severely depressed on

them and the EU opened a whole

research into it and

people are very concerned about this and

yet we've got studies showing

really positive impacts on depression

and anxiety.

And the thing I will say about that is

I'm not saying that people on Ozempic

are not having suicidal ideation, but

that is a little more nuanced of a

conversation because

number one, when you lose a significant

amount of weight very quickly,

all kinds of things can go wrong.

You can end up with pancreatitis. You

can end up with gallstones. You can end

up with

severe depression. Your fat stores your

hormones. And so, you lose your hormones

very quickly. I've had patients who got

tummy tucks and came in a few months

later and were losing their minds cuz

they literally just had all of their

hormonal depots sucked out of their

stomach. And so, there's concern there

that this rapid weight loss, which

again, I am not a fan of. I'm not a fan

of doing it that way, but if you drop

somebody's weight significantly, you may

end up with a very depressed mood state.

We've also got a bit

further to go with that in that many

people are using food as their dopamine

source and as their crutch or as their

coping mechanism. And I'm not judging. I

just understand that to be true. You

know, we all have our vice and if you

take that away from someone because they

suddenly don't want to eat

cuz we crushed their appetite with too

high a dose, then I think that we could

end up with a very depressed person in

front of us. However,

done correctly and what I'm seeing

clinically is people are having really

profound benefits in their anxiety and

their depression and their moods and

their cognition. Um I'm seeing

neurodivergent folks taking it who are

becoming much more functional in the in

their everyday day-to-day.

I'm seeing people who are

more of a hermit who don't want to go

out in the world suddenly venturing out,

being more social. So, there is an

impact on the brain and I think it's the

anti-inflammatory mechanism. I think

it's the dopaminergic system, the

dopamine pathways being impacted.

And again, if we're not cranking the

dose up, I think that we can use these

effectively to bolster mood, to improve

cognition, to improve brain clarity and

all of that leads, you know, an inflamed

brain is a depressed brain. At the end

of the day, we have to get that point

really clear.

Depression is a brain inflammation

issue.

You've mentioned sort of sexual health a

few times and fertility in passing

talking about Ozempic.

Women's sexual health, male fertility,

what is the the impact in your view of

an an Ozempic intervention on these

kinds of things?

Well, the fertility conversation is

really daunting and it's kind of a long

one, but

we are looking we are a few generations

into a major fertility crisis.

And they say, what is it by 2100? 2100.

By 2000 by 2100 97% of countries in the

world will not be reproducing at a rate

to repopulate themselves. We are looking

at a population crisis. By 20 by the

mid-2040s, they say sperm rates are

going to be at zero.

And

again, that's multifactorial, but

my firm belief at the root of this is

metabolic dysfunction. I I I firmly

believe that metabolic dysfunction is

probably the biggest driver. If I could

press a button and fix it, I would put

my finger on the metabolic dysfunction

button.

And GLP-1s heal metabolic dysfunction.

And so we're seeing reversal in PCOS,

which is probably one of the number one

drivers of

infertility in young women, period,

which is really at the end of the day

just metabolic dysfunction. It's just

presenting in women with high androgens.

The The clinical picture PCOS isn't

doesn't always involve um cysts on the

ovaries. It's just this

I don't even know why it's called that

anymore. It's a clinical picture where

they have metabolic dysfunction, they

have high testosterone, they have low

progesterone, their estrogen gets

converted readily into testosterone.

They end up with hair growth, they end

up infertile. It's a disaster. Many,

many young women. Many women in your age

cohort have this condition. Many women

in your Many couples in your age cohort

are not able to get pregnant without IVF

at this point. People are not getting

pregnant. I don't know How old are you?

31. Yes. People in their 30s are not

getting pregnant. And when I ask my

friends in their 30s all over the world,

I say, "What's Like how's How's the

pregnancy going with Like how how's it

going with your friends?" And they're

like, "Everybody's on IVF."

It's I don't know what you're hearing,

but it like that's crazy to me that

30-year-olds are having to do IVF.

Healthy-looking

30-year-olds are having to do IVF. So

we've got sperm issues and we've got egg

issues. It's both. It's not just the

female's fault, it's not just the male's

issue. Um we've got sperm health, we've

got sperm volume, we've got sperm

motility issues, we've got metabolic

dysfunction in both groups. And what

happens when

we do have a successful pregnancy is

that that offspring is being

epigenetically flagged

if the mother is obese and dealing with

metabolic dysfunction, and even if the

father is,

that fetus ends up bathed in insulin in

utero. And they come out epigenetically

marked for much more severe risk of

metabolic dysfunction and obesity in

their own lives.

And that cycle just goes into

perpetuity. That's where we're at. We're

several generations into this as a as a

species. And so I'm worried. Like I'm

legitimately I I joke that humans are

going extinct. It's not funny. And it I

think it's really happening and I I do

believe it will happen in the next few

generations if we don't right this ship.

And at the root of it is this

overarching metabolic dysfunction. 2018

data

out of the US

that was published in 2021 showed that

only 6.8%

of US adults are metabolically healthy.

6.8. That So that's

93 94% of US adults are

cardiometabolically busted.

That's And that was pre-lockdowns.

Why?

That's a great question.

You know, you talked about PCOS and this

sort of infertility crisis, and then you

talked about it being about metabolic

dysfunction. Yeah.

Where is the metabolic dysfunction

coming from? What is the thing furthest

upstream if we were to attack it at its

source?

Yeah. The food supply was significantly

adulterated in the past few generations.

So it's starting with my parents, the

boomers. You know, they got their

convenient food. Their everything was

about convenience. That's when we got

you know, disposable diapers and

fancy microwaves and dishwashers and all

that jazz. Well, food became very

convenient as well. In the '90s, I

watched this happen in my lifetime. In

the '90s,

the food supply was significantly

adulterated and terrifyingly so. And

they found the bliss point, right? The

perfect emulsion of sugar, fat, and salt

to hit those

neurotransmitters in the brain to make

you want to come back for more.

Toxicity is a huge issue. I believe

toxicity in general, not just

environmental toxicity, but it's the

chemicals in our food, um what we're

doing to ourselves. So many young women

today are bathing themselves in toxic

chemicals through their beauty habits. I

mean, the nails and the hair and the

skin care and

it's it's really, really severe. So it's

this sort of multifactorial thing.

Humans are actually eating the same

amount or less calories than they were

30 years ago. It's not the caloric

intake. It's not that people are sloths

and they're lazy and they need to do

better. It's that we are swimming in a

toxic soup. We are eating a very

adulterated, mineral-deficient,

protein-deficient,

chemical shitstorm of a food supply. And

then you throw in the mass I mean, to be

totally honest with you, the massive

uptick in vaccines in

infants when they come out, I mean,

that's a whole different ballgame than

it was even when my daughter was an

infant. It's significantly different

than when I was an infant.

So we've just We've got a lot of things

coming at these young people. And it

culminates, you know, and it adds up.

And I think people don't realize we have

a toxic bucket. We all have an

individual toxic bucket. And that bucket

will become full for whatever reason.

Maybe we've got mold exposure. Maybe

we've got too much stress. It's It's

multifactorial, but that bucket will

fill up and overflow. And

metabolic dysfunction is a result of

that and also a driver of that.

So it's it's very hard to put my finger

on why or the chicken and egg, what's

what's leading to what. I know that

there's things we can do that are

non-negotiable to help right the ship as

best we can that have nothing to do with

drugs and have nothing to do with

peptides. And I've been talking about

this for decades. We must be strength

training and optimizing our muscle.

We must be

walking every day like human beings do.

Humans were made to walk and lift heavy

[ __ ] right? We are meant to be in

community. We're not meant to be

isolated. We're meant to be around

others. We are meant to share our

microbiomes. We are meant to have

healthy microbiomes, not these super

sterilized microbiomes. The abundance of

microbiome disruption from all the

antibiotics. I mean, that alone causes

lifelong issues for people. And so

it You stack all this up and people are