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The Truth About Creatine & Exercise! 30% Of People Will Die From This! The Healthy Ageing Doctor

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The Truth About Creatine & Exercise! 30% Of People Will Die From This! The Healthy Ageing Doctor

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2585 segments

0:00

Runners who only run are hurt a lot and

0:02

it's usually due to emotion imbalance so

0:05

I always do this test to show them

0:06

whether your butt muscles are strong

0:08

enough to keep your pelvis straight and

0:10

whether you're strong enough to keep

0:11

your knee from falling into this

0:13

position I look like I'm drunk or

0:14

something how are you doing this with

0:16

your heels on Dr vond Wright is a

0:18

leading orthopedic surgeon and Longevity

0:20

expert leveraging her expertise with

0:22

Elite athletes to revolutionize the way

0:23

we move eat and train to live longer

0:26

stronger and better I'm on a rampage to

0:28

make bones sexy again because in the

0:31

United States at least 50% of women will

0:34

get osteoporosis along with 2 million

0:35

men now osteoporosis is low bone density

0:38

and studies show that people with low

0:40

bone density have higher cognitive

0:42

decline it increases your risk of

0:44

fracture if you break your hip 50% of

0:46

the time whether you're a man or a woman

0:48

you will not return to preall function

0:50

and 30% of the time you will die and

0:52

there's a lot that causes bone fragility

0:54

such as aging not building enough bone

0:56

in our youth it's our sedentary

0:57

Lifestyles the myth that women have to

0:59

be teeny tiny and it's even things like

1:01

a woman breastfeeding will lose 20% of

1:03

her bone density in the first 6 months

1:05

but it's not inevitable and I will lay

1:06

out a lifestyle that I call unbreakable

1:08

it's about muscle bone nutrition but the

1:10

most important part is mindset I'm very

1:13

very excited uh just to pause that is

1:16

there a link between menopause and brain

1:18

density yes and it's because of the

1:20

plummeting of estrogen which is critical

1:22

for muscle bone tendon ligament fat and

1:25

without it it can have dire effects so

1:27

you need to know the following

1:32

this has always blown my mind a little

1:33

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1:36

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2:00

[Music]

2:03

Dr vonder Wright yes for anyone that's

2:08

unaware of what you do and who you do it

2:10

for what do you do and who do you do it

2:12

for so you know in as a sports doctor

2:15

over the years we've learned how to take

2:17

really high- performing athletes you

2:19

know those are who are winning all the

2:22

time who need to continually get better

2:24

and better and better at their craft and

2:26

over the 30 years of my career we've

2:29

gone from really focusing on how they

2:32

train the periodization of their

2:34

training to the last time I uh was at

2:39

the University of Pittsburgh I was the

2:40

medical director of the UPMC Lemieux

2:43

sports complex which is where the

2:45

Pittsburgh Penguins are housed and it

2:47

had gotten so uh scientific they had a

2:50

full-time Chef every meal from breakfast

2:53

lunch dinner every meal on the planes

2:55

were prepared because when it comes down

2:58

to split-second agility

3:00

top of brain thinking every little bit

3:03

counts and so in the 30 years of my of

3:06

my medical career it's gone from just

3:08

learning more about performance science

3:10

of how to train to how to feed people to

3:15

how to recover people so instead of

3:18

doing for instance I think Dara Torres

3:21

was talking about her uh Olympic runs in

3:24

her 40s right she trained much

3:25

differently when she was 24 and in her

3:28

40s after she had had a child it was

3:31

much more about recovery not as much

3:32

hours in a pool so I take all those

3:36

things that we've learned over this

3:37

course of my career and now apply them

3:40

not only to athletes but to people like

3:42

you and me who were in high performance

3:44

jobs I need to be tip toop in every

3:46

sphere of my life as you do and how do

3:49

we eat better recover better take the

3:51

principles of performance that we've

3:53

learned from athletes into high

3:56

performers and even mere mortal athletes

3:58

like me I love of my work involves like

4:00

cognitive performance making sure my

4:02

brain is sharp when it needs to be yes

4:04

how much of your work crosses over into

4:06

the cognitive realm you know I am not a

4:09

brain scientist myself but I am

4:11

fortunate to be surrounded by people who

4:14

are expert in that so from my own

4:17

perspective I've come to appreciate at a

4:20

much deeper level personally um as well

4:23

as professionally the role of sleep in

4:26

fact we've talked about my previous

4:28

books from the early 2000s before and

4:31

when I wrote those books Mobility was

4:33

King I wrote only about mobility and

4:36

then as I progressed in my career I got

4:38

deeper deeper deeper into nutrition and

4:41

then I would say okay nutrition is

4:42

number one and Mobility is second but at

4:44

this phase of evolution of sleep science

4:48

and knowing how restoring the brain and

4:50

providing adequate time and nutrients I

4:54

put sleep first sleep and Recovery first

4:56

because you can't do any of these other

4:58

things without a r well recovered brain

5:01

in fact somebody asked me the other day

5:04

about timing of working out and is it

5:06

always necessary to do it in the morning

5:08

like that's the Mantra get up go do your

5:10

workout and my answer to that was you

5:14

have to know how your brain works for

5:16

instance my brain is best between 5:00

5:19

a.m. and 2: p.m. that is when I'm going

5:21

to get all my deep work done I'm going

5:23

to be creative I'm going to think after

5:26

2 p.m. I could build you a house I can

5:28

continue operating but if I'm going to

5:30

write a book it's going to be early so I

5:33

do not work out in the morning because

5:35

I'm not going to waste that brain

5:37

energy on physical activity when I need

5:41

it for this deep work so that's the way

5:44

I apply brain science but I I'm so lucky

5:47

to be surrounded in in the place I am

5:49

now with people who put eegs on your

5:52

head and map your brain and tell you

5:54

which brain Pathways you're too

5:56

stressful on and and which brain

5:58

Pathways we can train and you can train

6:00

the physical brain like a muscle you can

6:03

train the physical brain like a muscle

6:05

yeah so there's this company called

6:07

nestry that I just happen to have access

6:09

to and they put EEG helmets on my

6:12

Precision longevity clients and we map

6:15

their brains and look at for instance

6:18

here's an example things that are

6:20

habitual take very little brain injury

6:23

uh energy even if we need a lot of brain

6:25

energy they become so habitual our brain

6:28

turns away uh energy from them versus

6:31

things we're learning or things we're

6:33

stressed about we devote so much energy

6:35

to that so once they this company Maps

6:39

our brains then they have this training

6:43

program where it's almost like getting

6:46

your your cognitive brain out of the way

6:49

and let your subconscious brain reapply

6:52

energy to the pathways that you actually

6:54

need that you you've begun to to ignore

6:57

and it makes you more efficient and I'm

6:59

being an adequate in explaining it but

7:02

brain scientists believe that you can

7:04

retrain the brain like a muscle and

7:06

devote energy to neurop Pathways so I

7:10

know we do this to athletes to try to

7:12

squeeze performance out of them when you

7:14

use that term Precision longevity what

7:17

does that mean so you know after the

7:20

understanding of human DNA knowing what

7:23

we're truly made

7:25

of it pushed us out of a time in

7:28

medicine

7:30

where we've been for the last 150 years

7:33

which is

7:34

Observe and one size fits nobody now

7:39

that we've sequenced the human genome we

7:41

can develop Health Plans your health

7:45

plan my health plan it's not generic

7:48

here's an example when I have people who

7:51

want to talk to me about living

7:53

healthier longer and we and we draw a

7:56

set of biomarkers it's not 6,000

7:58

biomarkers it's just a set of about 23

8:00

that are Beyond regular labs and I see

8:03

that for instance maybe stevenh you have

8:05

a high load of senescent cells well I'm

8:08

going to specifically design your Gap

8:10

nutrition according to what you need you

8:12

might not need anything for inflammation

8:15

because maybe your inflammation labs are

8:17

good but historically what we would have

8:19

done is say okay let's just give

8:21

everybody the same formula but now we

8:23

are able to devise what your body needs

8:26

at your time I do the same thing with

8:27

exercise I never say let's have you do

8:30

150 minutes of moderate exercise because

8:34

I have access to lactate threshold

8:37

testing where you're walking on a

8:39

treadmill running on a treadmill or on a

8:41

bike every four minutes we're pricking

8:43

your finger and I can tell exactly what

8:46

when your mitochondria the little energy

8:49

storehouses in your cells go from

8:51

burning fat to burning Caro

8:54

carbohydrates and that place is called

8:57

the fat Max and that is when your

8:59

mitochondria your energy organel are

9:03

most efficient and that's where we want

9:05

to work out 80% of the time so that's

9:09

just an example of how I'm going to tell

9:12

you what heart rate you need to work out

9:14

in I'm going to tell you how to get fill

9:16

the gaps in your nutrition instead of

9:18

just doing broad guidelines because

9:21

that's the state-of-the-art right

9:23

now when you think about personalization

9:26

I was thinking also not just about the

9:28

individual but different phases of life

9:30

and how maybe in my my 20s there's a

9:33

certain set of things I need to be

9:34

thinking about more so than in my 30s my

9:36

40s and my 50s and my 60s is that a

9:38

useful way to think about it are there

9:40

different things we need to be thinking

9:41

about in different seasons of our life

9:43

or is it the same things in every

9:46

season well I love that question and the

9:50

one one word answer is yes every season

9:54

of our life is different let's take

9:56

bones for

9:57

instance we build build build build

10:00

bones yeah until in women we're about 28

10:03

and uh men 30 we reach Peak bone mass we

10:08

then reach a plateau where we keep our

10:09

bone density and then in women it begins

10:12

to plummet due to hormonal influences

10:15

for men men usually maintain their bone

10:19

density until their 70s when they

10:21

plummet unless they have a metabolic

10:23

problem an autoimmune disease or having

10:26

had the need to take a lot of steroids

10:27

and then you see a big difference at 50

10:30

so in Bones that's a good example how

10:33

every few decades our bones are reacting

10:36

differently muscle is the same way we

10:39

know that we can gain muscle at any time

10:42

in our lives but we do it most easily

10:46

until we're about 30

10:48

right we also know of uh changes in the

10:53

way our gut functions as we age having

10:56

to do with absorption and the uh the

10:58

ability of the microvilli in our gut to

11:01

absorb nutrients and different kinds of

11:03

nutrients women in midlife for instance

11:06

need vitamins that are something called

11:08

methylated which means broken down a

11:09

little more because our gut function is

11:12

less efficient so every phase of our

11:14

aging were different well on that point

11:17

of bones that that sounded like you were

11:19

saying men's bones maintain their

11:21

density longer and women don't why why

11:24

is that and is that linked to menopause

11:26

well men uh because of the influence of

11:29

testosterone and the genetics of having

11:32

um XY chromosomes build more bone

11:35

initially thicker cortices more more

11:38

absolute poundage of Bones and so um and

11:41

then because of the plummeting of

11:43

estrogen which is critical for bone

11:45

health women lose bone faster than men

11:48

such that after about age of 40 when we

11:51

get to that Plateau women start to lose

11:54

bone density about 20% by the time they

11:58

get to their menop pause and um that can

12:01

have dire effects for women but that is

12:03

all due to the role of estrogen on

12:06

controlling bone density so is this

12:09

inevitable is the loss of bone density

12:11

inevitable for women it is not in um in

12:15

2004 we studied a very large group of

12:18

Masters athletes meaning athletes uh 40

12:21

and older in the National senior games

12:24

which is Olympics for uh people of that

12:27

age demographic and the National games

12:30

you have to have won your State Games to

12:32

qualify so these were pretty highlevel

12:34

recreational athletes so we did a study

12:37

looking at their bone density across

12:39

time and the first thing the first study

12:41

we found was that with chronic exercise

12:45

such as these people did you can

12:47

maintain your bone density at a very

12:49

high proportion into your 80s the second

12:51

question we asked was okay if we know we

12:55

can do that what exercise is really

12:57

important for that and so we divided

12:59

Sports up into uh bounding Sports where

13:02

the bones were being impacted like like

13:05

basketball running um volleyball

13:08

anything when you come down hard on your

13:10

bones versus swimming bowling the less

13:13

biking and we found that bashing your

13:17

bones impact was as important in

13:20

maintaining bone density as things you

13:22

can't control like your age whether

13:25

you're born with XX chromosomes or XY

13:28

chromosomes family history so impacting

13:32

bones causing them to build up over time

13:35

is critically important for maintaining

13:37

bone density so to answer your question

13:40

is loss of bone density inevitable loss

13:42

of estrogen is inevitable loss of bone

13:45

density doesn't have to result in

13:48

osteoporosis fracture and

13:50

Frailty so I want to get into why that's

13:52

happening but just to pause there

13:54

because a lot of people don't think

13:55

bones are that important oh like I think

13:57

a lot of people see our bones as just

13:58

some thing that yeah we can't influence

14:01

you don't think of them like muscles

14:02

muscles I go to the gym I can expand my

14:03

muscles I can get strong but with bones

14:06

it feels like they're static you know so

14:09

how how would you refute that so that I

14:12

start caring about my bones and what is

14:14

the cost if I don't care about my bones

14:17

well you know what I'm on a rampage for

14:19

this year that to bring to make bones

14:22

sexy again CU here from a very

14:24

superficial level is why we should care

14:26

and then I'll tell you from a more

14:27

scientific level

14:29

you know we only think of our bones

14:31

usually in a couple times like you look

14:34

in the mirror and somebody tells you oh

14:36

your bone structure is magnificent look

14:38

at this model's bones and or uh and

14:41

we're all touching our cheekbones or we

14:43

think about them when we hear about a

14:45

great archaeologist who's just

14:48

discovered a new people group and we can

14:50

tell from our bones how they lived how

14:53

they died how healthy they were in fact

14:56

in that setting bone is the last remnant

14:59

of your whole life it endures the

15:01

longest I mean the hisory the history

15:04

you talk about in your bones outlives

15:07

anything muscle goes away skin goes away

15:10

everything except your bones which

15:12

remain that's fascinating right

15:17

but the other reason we even think about

15:19

our bones is when they break right when

15:22

they bones people think bones are silent

15:25

like a strong silent type just hanging

15:27

back

15:29

until they break and then they're

15:31

screaming at you right and and causing

15:34

Frailty and here's some bone stats

15:36

because the real answer to the question

15:38

is coming one in two women will have an

15:41

osteoporotic fracture in her lifetime so

15:43

it's either me or your partner or me or

15:46

your assistant right one in two will

15:49

have an osteoporotic fracture women have

15:52

70% of all hip fractures hip fractures

15:55

are one of the main contributors to

15:57

ending up in a nursing home because you

15:59

can no long walk and take care of

16:00

yourself right 70% are women if you

16:04

break your hip 50% of the time whether

16:07

you're a man or a woman you will not

16:09

return to preall function you cannot go

16:11

live in that house where you raised your

16:13

children you may not be able to drive

16:16

and go be totally independent right and

16:17

30% of the time it's a huge number 30%

16:21

of the time you will die either from the

16:25

complications of the fracture from the

16:27

bed rest from the in infections you get

16:29

the bladder infections just the sequele

16:32

of being that sedentary so those are

16:36

those are not meant to scare people that

16:38

is the reality that I see every day as

16:40

an orthopedic surgeon on

16:42

call but there are other reasons to

16:44

carry about the bones because fracture

16:46

is a big one

16:48

bones and it makes sense nature is so

16:50

conservative bones are in our body from

16:54

the top of our head to our pinky toe

16:56

right bones are master

16:59

communicators we think of muscle which

17:02

we're all talking about now and Bone and

17:06

adapost and everything as as siloed

17:10

organs that don't have much to do with

17:12

each other except they live next to each

17:14

other the fact of the matter is for

17:17

instance when we're talking about the

17:19

musculoskeletal system bone tendon

17:23

ligament muscle fat cartilage muscle

17:26

stem cells there are all all derived

17:29

from the same stem cell the mesenchimal

17:31

stem cell so they're not distant

17:35

neighbors they're

17:37

cousins and they all speak in the same

17:39

language they may have different

17:41

dialects I was thinking about an example

17:43

of of this you know how in the UK

17:46

English is the language but depending on

17:48

what parish you live in or which country

17:50

within the UK English sounds very

17:53

different but it's the same language So

17:56

within musculoskeletal tissue isue

17:59

muscle and bone are not separate they

18:02

are one ecosystem such

18:05

that when muscle releases a protein

18:10

called irisin it talks to the Bone when

18:13

bone releases a protein called

18:15

osteocalcin it talks to the muscle but

18:18

in the case of

18:19

bone osteocal if we just stick with that

18:23

protein it talks to the whole body when

18:27

your osteoblast s the bone building

18:30

cells in your bones released osteocalcin

18:33

it goes to your brain and has a

18:35

neuroprotective effect by decreasing

18:37

inflammation it goes to your brain and

18:40

causes the synthesis of neurons in the

18:44

hippocampus it goes to the pancreas and

18:47

helps with insulin insensitivity it goes

18:50

to the muscle and helps the muscles

18:53

scoop up glucose out of the blood right

18:56

if you're a man osteocal can travel to

18:59

the testes and that organ the litig

19:02

cells under stimulation of osteocalcin

19:05

will produce testosterone so it's like a

19:08

miracle and a wonder that we just think

19:11

of Bones as the strong silent type that

19:14

hold up our

19:16

muscle because actually bone and and the

19:19

proteins that it produces are Master

19:22

communicators and it makes so much sense

19:25

because we have bone everywhere in our

19:27

bodies why wouldn't our body bodies use

19:29

it like that I thought it was just a

19:30

frame well and it is a frame right

19:33

what's Muscle without bone just a heap a

19:35

metabolic tissue right it makes us gives

19:38

us our statue but it's a master

19:41

Communicator the framework is almost a

19:44

secondary job in my opinion the bone is

19:47

releasing stuff I got this

19:50

um

19:52

this little analogy I'm going to put on

19:54

the table in one of the one of the tubs

19:57

I've got some mineral some and then this

20:00

is the body yeah so could you explain to

20:02

me how the the bone is releasing

20:06

something into the body so we've talked

20:08

about the bone being structural right it

20:10

holds you up it gives you your stature

20:13

we've talked about bone being a master

20:15

Communicator another job of the bone is

20:19

as your body's

20:20

Storehouse to really really important

20:23

maybe if we just talk about one of them

20:25

calcium calcium is is a critical mineral

20:28

in our body we need it for muscle

20:31

contraction for pushing um molecules

20:34

across cell

20:35

membranes but we've got to store it

20:37

somewhere so when we eat food our body

20:41

pull our intestines pull it out of the

20:43

food we eat and stores it in our bones

20:48

and so our body is always sensing how

20:50

much calcium how much phosphorus do we

20:52

have what do we need when our body

20:53

senses that we need more it goes to the

20:56

Bone it tickles the osteoclastic and say

20:59

osteoclast we need some more calcium the

21:02

osteoclast breaks down some bone

21:04

releases calcium and it goes into the

21:07

body for

21:09

use and then the body has enough to use

21:12

the body does not just keep piling it in

21:14

because

21:15

hypercalcemia causes heart arhythmia

21:17

it's bad right the body is perfectly in

21:20

homeostasis in Balance so when the bone

21:23

has released enough it sits back and

21:26

keeps storing it right

21:29

the calcium your body doesn't need if

21:31

the bone is

21:33

full it's excreted through the kidneys

21:36

and this is a really fine balance

21:38

between building bone releasing the

21:41

storehouse of minerals into the

21:44

bloodstream or saying oh we've got

21:46

enough let's send it out in our urine

21:49

the body is such a miracle like that so

21:52

if I don't have enough calcium or some

21:54

of these other minerals does that mean

21:56

that my bones are going to become

21:58

fragile

21:59

so you know there are lots of things

22:01

that go into bone fragility or

22:03

osteopenia and one of them is not laying

22:07

down enough bone in our youth if we T

22:09

you asked me earlier about changes

22:11

across a lifespan when it comes to Bone

22:15

what's interesting is that I get very

22:17

very young women in my clinic for 25 28

22:22

whom for various reasons I do a bone

22:24

density test on and they are already

22:27

have brittle bone

22:29

I know it's it's it's shocking well I

22:32

think that happens for a number of

22:33

reasons number one we didn't build

22:35

enough bone there is still a myth in

22:37

this country that women have to be teeny

22:39

tiny that we have to starve ourselves

22:41

and when that happens many women do not

22:43

have consistent menstrual cycles and

22:47

estrogen which then helps us lay down

22:49

bone so that's number one we don't

22:52

estrogen plays a role in laying down but

22:54

yes it does critical role so we're not

22:55

laying down enough or maybe

22:58

we're athletes we're in we Title 9 which

23:02

is the law that um equalize sport for

23:05

women in college is 53 years old so

23:09

maybe young women are not laying down

23:11

enough bone because they're expending so

23:13

much energy 10,000 calories a day and

23:16

then they're not refeeding in the way so

23:18

they're always living in a state of

23:20

energy

23:21

deficit and not laying down enough bone

23:24

or maybe young women are coming to my

23:26

office with not enough bone because we

23:29

are raising an entire generation of

23:30

sedentary children who are sitting

23:33

around in their basements on playing

23:35

games building brains but not building

23:40

bodies that is borne out by looking out

23:44

of the University of Wisconsin

23:46

Orthopedic researchers there studied

23:48

which women's

23:50

sports build the best bone and it's

23:53

gymnastics it is the pounding and the

23:56

feeding of those athletes that builds

23:58

the best best bone so we have trouble

24:00

with not enough brittle bones in

24:03

adolescence because we're not building

24:05

it the second place in the lifespan that

24:08

we may become low in bone density and

24:11

hear me people I am not saying not to

24:15

breastfeed I mean I in my children I my

24:18

child I breastfed for a year it's really

24:20

great for

24:21

babies

24:23

but a woman breastfeeding will lose 20%

24:26

of her bone density in the first 6

24:28

months of breastfeeding and if she's not

24:29

really careful to get 500 milligrams of

24:32

calcium a day in her food or through

24:37

supplementation she will not build it

24:39

back and then if you have children in

24:42

ear in succession because many women are

24:44

waiting until 30s to have their first

24:46

child and then have less time we may

24:48

never build backbone so that's another

24:51

key point that people don't realize

24:53

could be dangerous to the bones and then

24:56

finally yes is this period about around

24:59

per menopause starting around 45 when

25:03

estrogen levels become very chaotic and

25:06

then ultimately zero that can cause the

25:09

rapid decline in bone density and Bone

25:13

weakness that you're actually asking me

25:16

about and that's because estrogen is

25:18

critical for controlling the absorption

25:22

this part the

25:24

absorption of bone and without estrogen

25:27

controlling the absorption it just keeps

25:29

breaking down bone faster than the

25:32

osteoblast the building cells can build

25:35

it so there's an an unbalance a

25:38

disregulation so I want to go into all

25:40

of that starting with the point you made

25:41

about um having doing Impact Sports when

25:44

we're younger yeah because like people

25:46

often say if you do Impact Sports when

25:47

you're younger especially some of them

25:49

there's other consequences like injury

25:51

or hitting your head so you're saying

25:53

that we should be running or jumping

25:56

when we're younger to build our our bone

25:58

strength absolutely to build everything

26:01

oh it's you know we we uh make

26:04

mitochondria most the energy of

26:06

ourselves we make a lot of mitochondria

26:08

in our youth if we're not active in our

26:10

youth we don't have the anabolic

26:12

stimulus as much to make as much

26:14

mitochondria if we are sedentary

26:17

children we will make bone but we will

26:19

not build bone to the extent we do if

26:21

we're bashing it every day and I and I

26:24

think the data out of Wisconsin is a

26:26

good illustration of that and is in all

26:28

seasons of life if I'm 60 years old

26:30

should I still be bashing that bone

26:32

playing basketball abs and that's what

26:34

my study from the national senior game

26:36

shows that by impacting your bones

26:38

across your lifespan you can change your

26:41

bone density so on that point of

26:42

pregnancy which was your second point

26:45

there during my pregnancy after my

26:47

pregnancy what do I need to be doing is

26:49

it drinking milk yeah so if and this is

26:52

the data I gave you was specifically for

26:54

breastfeeding okay so for breastfeeding

26:56

mothers uh you will lose about 500

26:59

milligrams of calcium a day as you're

27:02

making milk for your child you must

27:04

replace that I like people to replace

27:07

their calcium with whole food right with

27:10

prunes and dates and and high calcium um

27:14

Dairy if you will if you simply cannot

27:16

do that okay take a supplement but if

27:19

you forget to do that I mean I get it I

27:21

was a young mother I'm exhausted I

27:22

wasn't a young mother I was a

27:23

40-year-old mother

27:25

exhausted you have to be so mindful as

27:28

your the baby's latching on to eat some

27:30

calcium eat your yogurt eat your calcium

27:33

chew from Whole Foods if you will so

27:36

that you rebuild your bone which you're

27:38

completely capable of doing studies show

27:40

you will rebuild your bone but not if

27:42

you're not aware not if you're in the

27:45

I've got to lose the baby fat starving

27:46

phase let's not do that you talked to

27:50

about how bone has an impact on various

27:52

parts of the body and I've had you talk

27:54

about this phrase the bone brain axis

27:56

yeah what is the bone brain AIS well if

27:59

we just talk about um just choose one of

28:04

the the proteins that bone makes

28:07

osteocalcin so as that's released into

28:10

the bloodstream one of the places it

28:12

goes is into it through into the brain

28:15

and it can cause it can Aid in the

28:19

neuroprotective effects so what is that

28:22

mean under normal metabolism we um

28:27

develop free radical

28:29

through du due to normal metabolism cell

28:32

work um we develop oxidative stress and

28:37

osteocalcin works to decrease that

28:40

oxidative damage to repair cells in the

28:42

brain so that's number one number two it

28:46

stimulates the release of something

28:48

called brain derived neurotropic protein

28:51

bdnf factor which stimulates the growth

28:55

of neurons in a part of the brain called

28:57

the hippocampus which is involved in

28:59

memory and here's here's the opposite

29:02

side of it we know in people that have

29:05

low bone density they also have higher

29:09

brain cognitive dysfunction with age and

29:12

vice versa there's an association in the

29:14

literature with osteoprosis and

29:17

cognitive decline and vice versa I heard

29:20

you in the The Business Insider

29:22

interview do describe there being a

29:23

critical decade yes for bone health mhm

29:28

what is the critical decade I think the

29:30

critical decade for most of our health

29:31

Stephen is no later than 35 to 45 for

29:34

men and women that's because um we know

29:39

for

29:40

women that's when estrogen starts to

29:43

decline or become chaotic so when we're

29:46

in our 30s to 40s that is the time to

29:49

get all of our health habits together

29:51

it's time to get a physical to see what

29:53

your Baseline labs are I think it would

29:55

be critical for men and women

29:57

particularly men to get a baseline

29:59

testosterone so that in the future when

30:01

we're thinking about supplementing

30:03

testosterone we're supplementing back to

30:05

your particular level because in the

30:08

future let's say when you're 50 a man's

30:10

testosterone could be 600 which Falls

30:13

within the normal range but if he's

30:15

still feeling low energy not himself a

30:18

lot of tendon and ligus injuries well

30:21

his young testosterone might have been

30:23

800 or a th000 so I like people to get

30:27

baseline lab if they've never been to

30:29

the doctor before uh around 35 all

30:32

things so that we know what we're

30:34

returning you to number one number two

30:38

if you have been so busy with your

30:40

career and stepped away from any

30:42

semblance of mobility and resistance

30:44

training now is the time because had I

30:48

known then what I know now when I was 40

30:52

I was training for triathlons I was an

30:54

aerobic athlete right I ran I biked but

30:58

what I would have done then if with what

31:00

I know now is I would have been lifting

31:02

a lot of weight to build maximum muscle

31:06

while I still had the most hormones to

31:08

start at a better place because you can

31:10

build muscle but it's better to start

31:12

from a higher average so get some Labs

31:15

make a relationship with the

31:17

doctor get all your preventive screening

31:20

do not uh blow that off um develop the

31:24

habits that are going to carry you

31:25

through a lifetime whether it's smart

31:27

anti- inflammatory nutrition whether

31:30

it's getting into a resistance training

31:32

program building up your cardiac

31:35

machine I saw that you were running a

31:37

lot now and we want the highest possible

31:40

V2 Max that we can as we enter into

31:44

midlife because we never want as we age

31:48

to cross something called the fragility

31:50

line so V2

31:53

Max is the measure of it's the ultimate

31:57

measure of fit

31:58

how much oxygen you are capable of

32:01

pulling out of the air and diffusing

32:03

across your lungs into your

32:04

blood world class athletes I was just at

32:07

the US uh Olympic Center in Park City

32:10

Utah those athletes have a V2 Max of 75

32:13

80 sometimes 90 right mere mortals are

32:18

considered excellent when they have a V2

32:20

Max uh of around 50 for women around

32:24

50 so you can build V2 to Max and should

32:29

in the critical decade because once we

32:31

hit midlife we will decline 10% a decade

32:37

if we don't consistently build it up so

32:39

what does that look like so if I started

32:42

at 50 50 years old my last V2 Max was

32:45

when I was at when I was 50 and it was

32:48

50 it was pretty good because I was an

32:50

endurance person right just in whole

32:53

numbers by the time I turn 60 it's going

32:55

to be 45 70 40 80 35 I never ever ever

33:02

want to hit 18 if I'm a man or 16 if I'm

33:07

a woman because that is the level of V2

33:11

Max when we can't get up from a chair by

33:13

ourselves we when we can't walk across

33:15

the room because that takes cardiac

33:17

function and so the higher we get our V2

33:21

Max in our youth the more Runway we have

33:23

even if we don't continue to build it up

33:26

yeah I've got a family member that can't

33:27

walk upstairs without being out of

33:29

breath and it's so debilitating because

33:31

when you have grandkids and the

33:33

grandkids start running around and you

33:34

want to play with them it's so sad

33:36

watching this particular family

33:38

member see the grandkids come the

33:40

grandkids say let's play the grandkids

33:42

run off and this person can't go after

33:44

them so they just have to watch they

33:46

literally watch the the grandkids

33:48

playing in the garden because they can't

33:49

play with them and I think it's s such a

33:51

sad thing it's one of my big motivators

33:53

to try try and stay healthy is just to

33:55

be able to extend my health span that's

33:58

right so that I can be healthier

34:00

hopefully until the day that I die thatd

34:01

be great but would I want to talk about

34:04

running I want to talk about V2 Max to

34:06

close off on the subject of Bones

34:08

there's two terms that I that I want to

34:10

hear one is this term osteoporosis yes

34:13

now I have no idea what osteoporosis is

34:15

I've heard it a couple of times in my

34:16

life but I don't know if it's something

34:18

I should be thinking about worried about

34:20

um or what it means yes osteoporosis is

34:23

the word we use to describe low bone

34:25

density Okay so so the way we measure

34:29

osteoporosis is uh using an x-ray called

34:32

a DEA scan a dual X-ray and it just

34:35

measures it Compares your bone density

34:39

to that of a 30-year-old healthy person

34:42

and it gives us something called a

34:43

t-core so it's it's like when you're in

34:46

school and you're graded on a bell curve

34:48

and the center of the curve is average

34:50

and that's the average for a

34:53

30-year-old when you get a dexa scan

34:55

score and it's positive fan fantastic

34:58

you have bones of a

35:00

30-year-old if you get a t-core on a

35:03

dexas scan that's from 0 to

35:05

minus1 it's okay minus one is the

35:09

definition of osteopenia meaning watch

35:12

out your bones are getting weak the

35:15

definition of osteoporosis is minus a

35:18

t-core of minus

35:20

2.5 increases your risk of fracture by

35:23

40% or more all the bad statistics that

35:26

I talked to you about come with

35:30

osteoporosis and how many people have

35:32

osteopenia osteoporosis in over the age

35:35

of 50 in America well two million men

35:37

have osteoporosis interestingly isn't

35:39

that interesting you don't think about

35:40

it as a men's disease and uh one in two

35:44

women will have an osteoporotic fracture

35:46

so at least 50% of women but it's not

35:48

inevitable that's why I'm so interested

35:51

in in Catching people early in the

35:54

critical decade it's not inevitable but

35:56

it will be inevitable if we don't catch

35:58

it but here's the thing that's

36:01

bothersome in the United States and in

36:03

many other countries uh with people I

36:06

deal with you cannot get a dexa scan

36:08

paid for until you're

36:09

65 by 65 the damage is done why are we

36:13

waiting even with people who have had a

36:16

fracture there's a gap in followup such

36:19

that they should all have a dexa scan

36:22

because the number one thing that

36:24

predicts future fracture is past

36:26

fracture

36:28

so Public Service Announcement if you've

36:30

had a fracture get a dexa scan even if

36:33

it was a traumatic one like you had b a

36:34

car accident but definitely if you have

36:37

fallen if your dog pulled you down if it

36:39

was a low trauma fracture get a dexa

36:43

scan because then at least you'll know

36:44

where you are and can then plan a course

36:47

for building your bone are there any

36:49

early warning signs that I might be

36:51

suffering from osteoporosis or on my way

36:53

to

36:54

osteoporosis you know I think you can

36:56

get Clues from your own family okay if

36:59

your mother

37:00

shrank if you if you used to be able to

37:03

look your mother in the eye like me my

37:04

mother looked me in the i54 and now

37:07

she's way down here we lose height in

37:10

both men and women due to uh compression

37:12

of her spine vertebrae we lose height so

37:16

if your dad shrank if your mother shrank

37:18

that's a good indication that you have a

37:20

family history where osteoporosis can

37:23

exist or if your mother had a hip

37:26

fracture or or if for some reason maybe

37:30

asthma you've had to be on uh high dose

37:33

steroids your whole life or an

37:35

autoimmune that's very bad for bones so

37:38

from a medical standpoint from a family

37:40

history standpoint from a personal

37:42

standpoint usually fracture what about

37:44

if I'm a smoker does that have an impact

37:46

on my bone health and chances yeah I'm

37:49

really glad you asked that smoking is a

37:50

poison to Bone healing whether it is

37:53

fracture will heal more slowly in fact

37:56

we have a very a much higher rate of

37:58

non-union which is where we fix a

37:59

fracture and it still doesn't heal in

38:02

smokers we know that uh there is a big

38:05

body of data within the orthopedic

38:06

literature for people who have spine

38:08

surgery who are smokers they are not

38:11

only less healing but they're more

38:12

infected so the the noxious chemicals in

38:15

smoking are very bad for

38:18

bone good thing I don't smoke is that

38:21

smoking vaping or is it it's all vaping

38:24

might be more dangerous we just don't

38:25

have as much literature

38:28

okay and the the last thing before we

38:29

talk about running in fe2 Max and

38:31

endurance and sports and all those

38:33

things is the link between Alzheimer's

38:36

in bone health is there a link that goes

38:40

back to what we were talking about

38:41

before and there's a

38:44

correlation we I don't believe we worked

38:46

out the causation but there's a

38:48

correlation we see people with

38:52

Alzheimer and people with uh dangerous

38:55

osteoporosis are sometimes the same same

38:57

group 30% of the time people with brain

39:00

disease also of osteoporosis and it may

39:03

do be due to this uh connection that

39:05

we've talked about uh between the two

39:07

organ systems you had an aunt that

39:10

passed away from Alzheimer's I do my

39:12

aunt Ida she was brilliant she was a

39:14

teacher and she stopped remembering she

39:16

didn't remember herself she didn't

39:18

remember the farm that we were all

39:20

raised on that's a really hard thing to

39:23

witness um sometimes people with

39:26

Alzheimer's

39:28

lose the inhibition and they become

39:30

angry and enraged and afraid she never

39:32

did that but um but that's a hard thing

39:35

to witness how how did that experience

39:39

change you or change your focus or add

39:41

to the sort of what reservoir of

39:45

thoughts concerns reference points in

39:47

your life well you know what it has done

39:49

it has put an urgency and even it still

39:52

is a day-to-day battle I don't want I

39:55

think sometimes think people think for

39:57

me personally that because I talk about

39:59

these things all the time and I do lift

40:01

heavy and I do the thing I live the life

40:03

I prescribe for people that it's easy

40:05

and it's not easy you know I just I told

40:07

you IID finished this book I was writing

40:09

and there was a big gap in the

40:11

consistency of this lifestyle but what

40:14

motivates me to get back is the question

40:18

of what would it be like to live without

40:21

a brain that's

40:23

preserved I mean I don't know sometimes

40:25

I think about if I was aging and I had

40:28

to choose one would I choose an able

40:31

body or an able brain isn't that hard I

40:34

don't know that you do have to choose

40:36

but I can't fathom what life would be

40:39

like without an able brain and so for me

40:41

that motivates me to lift to make my

40:44

skeletal muscle secrete the uh proteins

40:47

that go to the brain and build better

40:49

brain to eat the foods that are not

40:51

going to clog my arteries it's just as a

40:53

motivator because I want to be this way

40:56

until I die

40:57

mhm what would you choose if you had to

41:00

an able body or an able brain my it was

41:03

super clear for me I'd rather have the

41:04

able brain me too me too relationships

41:08

that is that is the fullness of

41:11

Life protect but these things are also

41:14

fundamentally interconnected aren't they

41:15

that's why when I look at the alimer

41:16

stats around bone health I think well if

41:18

you were had osteoporosis or something

41:20

and you weren't moving as much maybe

41:22

yeah maybe you know what a huge

41:24

motivator for my patience is now that

41:26

you've brought this up

41:29

is Alzheimer's disease is thought of as

41:32

the third phase of diabetes right and so

41:35

everybody is aware of diabetes and it

41:37

means you don't process sugar and you

41:40

have glucose intolerance and your

41:41

pancreas is no longer functioning and

41:44

and the bad sequella that can come with

41:46

that what people are not aware of as

41:48

much at least as a people who come to my

41:51

clinic is pre-diabetes and if you don't

41:54

mind me diverging a little bit because

41:56

it's so important to disc question you

41:57

just asked me and can we prevent it and

42:00

and if we got to choose what would we

42:02

choose but I have people coming into my

42:04

office all the time and I look at their

42:06

labs and they have a fasting glucose

42:09

they've had their Labs drawn they've

42:10

done what we've said get in front of

42:11

your critical decade they've had their

42:14

fasting glucose drawn and it's

42:16

110 which is I'm going to tell you and

42:19

and their hemoglobin A1c is nearing six

42:23

so fasting glucose is the glucose that

42:26

remains in your blood after you haven't

42:27

eaten for 12 hours in a normally

42:30

functioning pancreas metabolic system we

42:34

want our fasting glucose to be around

42:37

85 right that's normal means we eat

42:41

something insulin comes out of our

42:43

pancreas the sugar is put into our

42:45

muscle and then the blood sugar is

42:47

around 85 if it's staying up 110

42:52

consistantly we know from the

42:55

literature that you have a 70 to 100%

42:58

chance of developing full-blown diabetes

43:00

within 10 years but what I see in people

43:04

coming into my office is I'll say did

43:06

anybody ever tell you you were

43:08

pre-diabetic and either the answer is no

43:11

or the answer is oh yeah somebody told

43:13

me they said just make a few you know

43:16

focus more on your exercise and and what

43:19

I think the reaction to pre the

43:22

diagnosis of pre-diabetes should be is

43:25

running and screaming to get healthy

43:27

because if we know that with a

43:29

consistent blood sugar in the

43:31

pre-diabetic range and we're casually

43:33

told by our healthare provider oh just

43:36

go try to exercise more you know just

43:39

casually approach this don't eat so many

43:41

carbs that is not serious enough because

43:44

we know from a preventative standpoint

43:46

from a Precision longevity standpoint

43:49

which is all about prevention we can

43:51

prevent you from getting to diabetes in

43:53

the next 10 years if we're really really

43:55

serious about lifting weights about

43:59

cardio Health about anti-inflammatory

44:01

nutrition following so I don't view

44:04

pre-diabetes as a casual thing at all

44:08

because if in a 10 years you're going to

44:10

get diabetes and in 10 more years you're

44:12

going to have Alzheimer's disease and I

44:15

could have prevented that by paying

44:16

attention when I was

44:18

40 it's almost inexcusable that we're

44:20

not paying more attention to it 96

44:23

million people in the United States have

44:26

pre-diabetes

44:27

96 million 96 million according to the

44:29

American Diabetes Association I just

44:31

gave a talk at their annual

44:33

convention 96 million have a

44:36

preventable

44:38

characteristic that we can prevent them

44:40

from becoming diabetic and getting

44:42

Alzheimer disease and yet it is too

44:44

casually spoken

44:46

of that's like almost one in three that

44:48

means that there's three of us in this

44:50

room so Jack's

44:51

got pre pre-diabetes perhaps potentially

44:55

you're an you an an urance athlete

44:57

wouldn't you say I was an endurance

44:59

athlete and I'm I've been I don't have

45:00

it today it ran out but I'm a little

45:02

obsessed with continuous glucose

45:04

monitoring so I've been wearing it for

45:06

about 18 months and and uh it's so

45:10

interesting I told you that you know I

45:12

just finished this book and I've gotten

45:14

a little bit off my regular intensity

45:16

and it changes my blood sugar so I run a

45:20

little I because I haven't been lifting

45:22

four times a week only twice a week

45:24

because I haven't been sprinting twice a

45:27

week like I Norm my normal regimen is I

45:29

lift heavy four times a week I on the

45:32

other days I do about four days of Bas

45:35

training Zone too two of those days I

45:37

Sprint I always eat a lot of protein

45:39

that is my

45:41

lifestyle and my blood sugar is 85 when

45:44

I do that and I'm a midlife woman and

45:47

you know the metabolic things that

45:48

happen to midlife women even backing off

45:51

a little bit starts to creep up my blood

45:53

sugar so this is a constant daily

45:55

habitual lifestyle that we all need to

45:58

lead and so when I see that and someone

46:01

as healthy as me when my patients show

46:03

up and they casually been told that they

46:07

have something that's going to kill them

46:09

I don't think that's enough attention

46:12

that's what I've been thinking a lot

46:13

about recently is what diet is going to

46:15

lead me to better cognitive performance

46:17

to someone that spends a lot of my time

46:18

talking yes but then also I'm on stage

46:20

I'm in boardrooms and in meetings and in

46:22

negotiations I'm reading emails and

46:23

writing books Etc so I'm always thinking

46:26

if I can just get 5% Edge well I can

46:28

tell you for instance the the dietitians

46:31

and chefs that make the food for the pro

46:33

athletes that I've taken care of across

46:35

my life they're not only eating meat

46:39

they have a very well-balanced diet that

46:41

includes lots of vegetables lots of high

46:44

protein they they take amino acid

46:46

supplements if they need to fill in the

46:49

gaps right if they're not getting enough

46:50

Lucine or something but they just don't

46:52

go down one one pathway I haven't seen

46:56

that in the Pros that I take care of he

46:59

to has given me a very sharp mind has it

47:01

an extremely sharp mind it's so

47:03

interesting as a podcast when you sit

47:04

here and you have all these

47:05

conversations because some days you show

47:07

up and sometimes these conversations

47:09

last for four hours and your brain and

47:11

mouth just don't feel like they're

47:12

connected yeah and then on other days I

47:14

come here like boom boom and it's

47:16

automatic yeah it's like I don't have to

47:18

think and it's just flowing off off my

47:20

mouth and the variance the big I said so

47:22

the causal factors are obviously sleep

47:24

is one of them the other one is how many

47:27

carbohydrates I've had in recent yes

47:30

hours so if I've had a lot of carboh

47:33

hydrates something you know like if I've

47:35

had bread my mouth and my brain have no

47:38

connection if I've had lots of sugar my

47:40

mouth in my brain are completely done

47:42

agreed agreed you know because of this

47:44

CGM thing I found that if I only eat

47:47

protein for breakfast which uh egg white

47:50

omelette or you know whatever just

47:52

protein that I needed a little complex

47:56

carbs in order

47:57

for about 10:00 in the morning to be

47:59

able to function at a high level with my

48:01

patients so now I've added 50 gr of

48:03

carbs in the morning but that's not a

48:05

lot of carbs not very much I just needed

48:07

that little complex but uh interesting

48:10

right and what do you eat I eat 130

48:14

grams of protein a day there's no upper

48:16

limit on how much protein you can eat in

48:18

a single setting I try to get at least

48:20

30 because there is a lower thresholds

48:22

for 30 and so if I do that uh it takes

48:25

three meals and a couple SN a day I

48:28

that's a lot of volume of food so I try

48:30

to eat really dense so uh a cup of Greek

48:34

yogurt is like 18 grams and a really

48:37

pure beef stick is another 16 so at this

48:40

time I at this point I've

48:42

memorized the most dense foods that I

48:44

can to get that much protein it's a lot

48:46

of protein it's a gram per pound it's a

48:50

gram per pound and that's what I need to

48:52

build muscle Studies have shown that uh

48:55

eating high protein Al without lifting

48:57

as much as I want myself and others to

48:59

do will help maintain muscle and then I

49:02

eat a lot of vegetables I don't now I

49:06

hope people are not going to throw them

49:07

at me but I don't eat fruit except

49:09

blueberries fruit is Nature's dessert so

49:12

if we're going to eat fruit eat it as

49:13

dessert I eat I eat blueberries with my

49:16

yogurt but um and then carbs I only eat

49:19

complex carbs if I eat them at

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off you're um a very big advocate of

50:26

muscle you know when we talk about

50:27

longevity something that you continually

50:29

come back to as the most important thing

50:31

for people's longevity I think I would

50:34

put muscle and bone near the same

50:37

category because you can have all the

50:38

muscle you want but if you break your

50:40

hip you still have the downstream

50:42

effects now you're much Les less likely

50:43

to break your hip if you're strong but I

50:46

think muscle or bone are really

50:47

important what if

50:50

you 65 years old 70 years old and you

50:53

haven't got MH strong muscles right now

50:56

now your muscles have um declined let's

51:00

say over the last couple of decades is

51:02

it too late never it's never too late it

51:05

is never too late your body will always

51:07

rise to the Strategic stress you place

51:10

on it so there are a lot of and growing

51:13

number of what used to be anomalies all

51:16

over the Internet of people in their 60s

51:18

7s 80s and Beyond in a gym powerlifting

51:22

becoming uh competitive bodybuilders so

51:25

even if you're starting

51:27

not being able to get up out of a chair

51:29

over a very short amount of time 6

51:31

months a year you can reverse the

51:34

trajectory of your Frailty but it takes

51:37

consistency right I do wonder that I

51:39

think about think about my father and

51:41

he's approaching his 70s now and I don't

51:45

think he's done weight training for the

51:46

last 15 15 years yeah and there is a

51:49

part of me that did wonder is it too

51:51

late now to to start doing weight

51:53

training because it's almost like a a

51:56

two-sided problem in the fact that you

51:58

haven't done it yes so you find it

52:00

harder so you don't do it so you find it

52:02

harder and then you sort of spiral down

52:04

to this sedentary State well and you

52:07

know what you do for that is nobody

52:09

expects you to start with powerlifting

52:13

squats deadlifts nobody expects that

52:16

moving our body through a range of

52:18

motion doing body weight progressing to

52:21

free weights progressing to like kettle

52:23

bells progressing to bands when once you

52:26

see that your body is capable of

52:28

adapting and

52:30

progressing you will get there pretty

52:33

rapidly I used to do this program called

52:35

a start where I would take people fresh

52:39

off the couch and over three months we

52:41

would get them to a 5K race because 5K

52:44

is a meaningful distance for people who

52:46

are sedentary and over that course of 3

52:49

months we did a series of um body weight

52:53

and kettle bell type exercises in a Circ

52:57

followed by walking and people started

53:00

with 51% body fat not being able to get

53:03

through the warmup not be able to hold

53:05

himself up in a plank and in three

53:07

months they could plank for 2 minutes

53:10

they could walk for three miles they

53:11

could keep going for the entire

53:14

10-minute circuit without having to stop

53:17

so there is never an age or skill level

53:19

when our body will not respond to the

53:22

Strategic stress you put on it so uh get

53:25

a trainer for your dad if he'd accept it

53:29

if he would accept it I'll call him

53:30

after this if I am trying to build

53:32

muscle are there a certain amount

53:35

of days of the week or repetitions I

53:37

need to do to build the muscle I think

53:39

about this a lot when I'm out here in La

53:41

I'm I'm I'm trying to make sure that I

53:43

don't lose my muscle but I spend a lot

53:44

of time sat down in here recording

53:46

podcasts so is there a certain amount of

53:49

times I need to work out that muscle

53:50

before I lose it you know I was just

53:52

reading this morning actually that um

53:55

even with a 10 week Hiatus from let's

53:57

say you're lifting consistently even

53:59

with a 10we Hiatus uh you will retain

54:02

muscle memory so that you don't make

54:04

serious declines which is little relief

54:06

to me because it's been a little while

54:08

with this book so you retain muscle

54:10

memory and you can quickly once you get

54:13

started again get back up to the place

54:15

you were um so all is not lost if you

54:19

take a few days off

54:22

but the minimum if we're really working

54:25

at it is a couple days a week

54:27

progressively lifting harder for men in

54:29

midlife it's about eight reps four sets

54:32

for women once we've trained to the

54:35

place we can lifting heavy four reps

54:37

four sets and when I say that out loud I

54:40

get a lot of comments about somebody's

54:42

going to get hurt well it's true but you

54:44

have to work your way up to that like

54:46

any sport you have to work your way

54:48

towards that level because what we're

54:50

trying to do by lifting heavier

54:52

especially for women is replace the

54:54

anabolic stimulus that estrogen

54:57

was you must work hard enough estrogen

55:00

creates growth we must signal our body

55:03

by the intensity of our work to build

55:06

muscle and lifting heavy does that so if

55:09

you're starting on the

55:10

couch uh start with bands start with

55:15

light weights start with the Mambi pami

55:16

pink weights that I rail against but

55:18

don't stay there continue to work your

55:20

way up in a progressive way to heavy

55:23

lifting total body at least twice a week

55:25

to maintain

55:26

do I need to increase the weight load to

55:29

build muscle because I wonder when I go

55:31

to the gym sometimes you know I might be

55:34

using smaller dumbbells but I'm doing

55:35

more repetitions yeah is that still

55:37

going to build muscle well it depends

55:39

what you want so so lighter weights

55:41

higher reps is uh

55:44

will will uh function for hypertrophy

55:47

for big bigger total muscle but not

55:50

necessarily power and strength in Lo in

55:53

midlife and Beyond I am Lifting for

55:55

longevity EMP power so I'm not as

55:58

interested as I once was in the bigness

56:00

of my muscle I'm interested in can it

56:04

move powerfully over times can I get up

56:08

off the floor can I lift my suitcase

56:09

above my head so Lifting for power is

56:13

lower reps higher weights so it just

56:15

depends what our goal is you may be

56:16

focused on hypertrophy right now which

56:18

is fine because you've not reach the

56:20

critical decade so if I'm looking for

56:22

hypertrophy yeah higher reps lower

56:24

weights so 12 12 15 reps low weight and

56:30

then if I was looking for power then

56:31

maybe 6 eight 6 eight that's right how

56:33

many do you do I do four you do four mhm

56:36

so big weight four big weights four reps

56:39

four sets interesting I didn't know that

56:42

M interesting

56:45

and just to give some sort of

56:47

foundational knowledge as to why muscle

56:49

is so important because some people

56:50

still might not um be aware of the link

56:52

between longevity and muscle a lot of

56:55

this is to do with from what I

56:58

understand glucose so it has to do with

57:02

muscle as the snc for

57:04

glucose uh it is a key factor in

57:08

preventing insulin resistance not to

57:10

mention strength staying upright not

57:13

falling down causing a fracture right so

57:16

muscle is a metabolic endrocrine organ

57:18

it releases when it

57:21

releases um you know one of the things

57:23

that releases is skeletal muscle

57:25

contraction by curls causes the

57:27

transcription of a protein called clo

57:29

which is the longevity protein about 30

57:31

years ago it was described in nature it

57:34

is the protein when muscle contracts

57:37

that's transcribed it works on every

57:39

organ we know that it's critical for the

57:42

longevity and repair of organs because

57:44

mice who are born without the ability to

57:47

make

57:48

clo die

57:51

old very young chronologically they're

57:53

very young mice but they die very old

57:56

mice because they have not enjoyed this

57:58

protein clo we make clo by the

58:02

contraction of skeletal muscle here's a

58:04

study I did uh years ago that showed

58:08

that I measured clo level circulating in

58:10

the blood of older Masters athletes

58:14

people 60 70 80 younger Master's

58:17

athletes 40 and sedentary people and

58:20

what I found that the highest levels of

58:22

circulating cloo the longevity pro

58:25

protein

58:26

we're in young athletes not surprising

58:31

the second highest level of longevity

58:34

protein clo were in Old Masters athletes

58:39

70 80 the lowest level of longevity

58:42

protein were in young sedentary people

58:45

so even old athletes had more

58:48

circulating

58:49

cloo than young sedentary people so just

58:52

the contraction of skeletal muscle can

58:54

add to your longevity through this

58:56

protein another Protein that's released

58:59

with skeletal muscle contraction called

59:02

ginin it is transcribed goes to the

59:06

brain works at a place called the

59:08

nucleus culus which is critical for

59:11

resilience it makes you more resilient

59:14

it helps you able to problem solve and

59:17

then you know a very popular uh protein

59:20

that is transcribed with skeletal muscle

59:22

contraction is called irisin it's the

59:24

exercise protein which you know it works

59:27

on bone it works on fat to Brown fat

59:30

from white fat to Brown fat which is has

59:34

higher thermogenesis it has higher

59:36

mitochondrial load it so muscle just in

59:40

doing its thing not just looking pretty

59:42

in a gym mirror does all these metabolic

59:44

functions and so that's why we think it

59:47

has such a key role in longevity so if

59:51

I'm trying to protect my muscle as I age

59:53

are there any supplements that I should

59:55

be taking

59:56

I mean do they sell cloo supplements

59:59

they don't you have to make it oh F

60:02

contract your own muscles well uh you

60:05

need to feed your

60:07

muscles I always quote people one gram

60:09

per ideal pound because listen I I I'm

60:12

an actual practicing person doctor and

60:16

here's what I know people need really

60:18

Specific Instructions and they can't be

60:20

confusing

60:21

so is there a range of protein people

60:24

need yes there is but people can

60:26

remember one gram per ideal pound so you

60:28

got to feed your muscle with protein

60:30

high quality protein the highest quality

60:33

protein has the greatest percentage of

60:36

an an essential amino acid called Lucine

60:39

Lucine is not made by the body it has to

60:41

be taken in from the outside it's a

60:43

branch train amino acid and you get it

60:45

from whey protein the best source in the

60:49

universe of Lucine and whey protein is

60:51

mother's milk but most of us don't drink

60:53

that as adults so we get it from dairy

60:55

products

60:56

you can get it from plants for everybody

60:58

that is a plant lover you just have a

61:00

much lower percentage you have to eat a

61:01

lot more of it so high quality protein

61:04

number one number two there's a lot of

61:06

research uh for uh creatine

61:09

supplementation for both men and women

61:12

when I first started being aware of

61:14

creatine in 1992 it was during the

61:17

Olympics I was working with a bunch of

61:18

wrestlers at that time um we would give

61:21

very very high doses we would cycle the

61:23

creatine we would come on and off now

61:26

steadily five uh grams a day will help

61:29

build muscle it will help build brain

61:31

it's really interesting a couple of uh

61:33

months ago I asked the people in my

61:36

office if they used creatine yeah and a

61:39

couple of the guys put their hands up

61:41

none of the women put their hands up huh

61:43

and I asked them why I said why didn't

61:44

use creatine they said that they thought

61:46

it was for

61:47

bodybuilders well it started out for

61:50

bodybuilders but it's for everyone

61:52

actually it's very well studied so I

61:55

actually had this um debate with my

61:56

girlfriend last year at Christmas time

61:58

um because I was taking creatine and

62:00

asked if she wanted some and she made

62:01

the same comment to me that it was for

62:02

bodybuilders and I she put on weight if

62:04

she had it and then I said no that's not

62:06

true so she Googled it and she saw that

62:07

it's good for like cognitive performance

62:09

skin hair muscle bone etc etc and now

62:13

she takes it every day perfect I think

62:15

there's a big um re-education piece to

62:17

be done there because we us we almost

62:18

used to think of it like uh a steroid or

62:22

something and it's not at

62:24

all you know what despite podcasts like

62:27

this and despite me screaming from every

62:31

Mountaintop I find that there still is a

62:34

an incredible knowledge deficit in the

62:36

general public about the principles of

62:38

how to be the healthiest we can be and

62:41

an even bigger Gap in the ability to

62:45

take action for ourselves I mean and

62:47

it's not a judgment it's simply an

62:49

observation that we know what to do but

62:51

we don't do it and we know what to do

62:53

and we don't do it even if we see in our

62:56

family someone who's going through the

62:58

throws of diabetes or even on the

63:00

Alzheimer's it's still not enough

63:03

motivation and I think that's the real

63:05

problem to solve motivation how'd you

63:07

solve

63:09

that sometimes sometimes we solve it by

63:11

scarce right you know someone has a

63:13

tremendous health problem but sometimes

63:15

that's not even

63:17

enough I have found that it is never

63:20

going to be motivating enough to try to

63:22

say okay if you do this today in 20

63:24

years you're going to be much better

63:26

there's this temporal disconnect people

63:28

just don't get it what they're going to

63:29

be like at 70 I think we have to make

63:31

you feel good every single day it's like

63:34

when we were talking about your brain

63:36

when you're doing heavy work and

63:38

cognitive work if you can feel better

63:41

every single day you'll continue the

63:42

behavior not for a promise so I think

63:45

that is the that is the

63:47

way to talk to anybody way I talked to

63:50

my patients can I make you feel better

63:51

tomorrow can I make you feel like a

63:54

badass cuz you lifted heavy weights

63:56

today um it's hard though with things

63:58

like bone you're telling someone that

64:00

they need to be getting I don't know

64:02

their calcium and stuff like that they

64:03

think well I can't see my bones and

64:05

osteoporosis is so far away that yeah

64:07

it's hard until you see someone fracture

64:09

or you fracture yourself I agree with

64:11

you vitamin D as well as crucial isn't

64:13

it for bone health I was reading that

64:14

there it is it is magnesium vitamin D

64:19

magnesium uh lesser known things

64:21

strontium zinc Boron and micronutrients

64:24

but big thing

64:26

vitamin D magnesium sleep sleep talked

64:30

about that a little bit as well how

64:32

important that was um you mentioned that

64:33

I'm running now yes you are thank you

64:36

for noticing you'd never mention it and

64:38

a million others are supposed to join

64:40

you I noticed yes we're going to try and

64:41

get a million people running that's

64:43

great you're going to save a lot of

64:44

lives oh thank you um but much of it

64:46

because of the work that people like you

64:47

do and that come on my show and inspire

64:49

me to think about things like my va2 Max

64:52

and I'd definitely been just weight

64:53

training for the last couple of years

64:54

not really thinking about my bones or my

64:57

V2 Max so this has been quite a big

64:59

shift for me yeah but when I think about

65:02

running I definitely hated it I still

65:04

hate it a little bit but I I hate and

65:06

love it now which is

65:08

progress what are the things I should be

65:11

thinking about CU people talk to me

65:13

about Runners knees and stuff like that

65:15

and I don't want to get injured right

65:17

but I'm running quite a lot so I hear uh

65:19

from a lot of

65:21

Runners that oh okay I'm going to lift

65:23

with my arms because I'm running so that

65:25

means my legs are going to get stronger

65:29

well what I know from 30 years in

65:32

practice is that Runners who only run

65:34

are hurt a

65:36

lot and here's why running builds a big

65:40

cardiovascular

65:42

engine but it does not build muscle mass

65:45

below your belly generally unless you're

65:47

running uphill all the time and you're

65:49

building glutes

65:51

but so what happens running is a single

65:54

leg sport if you if you look at a gate

65:56

analysis you're on one

65:59

leg at a time you're never on two legs

66:02

and walking you're in two legs on

66:03

running you're in one leg so if this is

66:07

if my hands are on someone's pelvis when

66:09

we're running we can't be going like

66:12

this every single stride sort of

66:14

oscillating oscillating like we're

66:16

walking on a catwalk in Fashion Week we

66:18

want to be running like this straight

66:22

well that takes tremendous glute

66:25

strength butt string because it's the

66:27

glutes that balance the pelvis if we

66:29

were in my office and you came in with

66:32

pain as a runner I would stand you on

66:34

one leg to see even if in a controlled

66:37

POS uh environment you could do a single

66:40

leg Squat and keep your pelvis stable

66:43

without your knee falling in and if you

66:45

can't it just tells me that we have a

66:46

lot of butt core and hip strength to do

66:50

and my lower back something I think

66:52

about because when I train especially

66:55

I'm training for a football match at the

66:57

moment oh um in the UK and I always seem

67:01

to get a glute injury so I and it's all

67:05

it's almost like 100% predictable that

67:07

if I don't stretch properly even even if

67:10

I stretch a little bit but don't stretch

67:11

fully yeah when I run on that football

67:13

pitch within five minutes I feel like a

67:15

little it's almost like a little tear in

67:17

my glute yeah almost yeah what am I

67:19

doing what do you think is happening it

67:21

might be useful to you as you're

67:22

training to have a motion analysis to

67:24

have someone stand you on one leg and

67:27

look at the way that that one motion

67:29

pattern is different from the other

67:31

because if it's predictable like that M

67:33

there's an imbalance in you and so it

67:36

can likely be trained I mean I can give

67:39

you an example in my life if you want to

67:41

see how that works so when I run and

67:44

when I increase my my speed and

67:47

distances I predictably predictably get

67:51

left Achilles

67:53

tendinitis and I get right hip flexor

67:55

sharp stabbing

67:57

pain predictably that is

68:00

because my left big toe from wearing

68:04

high heels all my life has arthritis so

68:08

when I run I don't run through the

68:09

center of my foot I run through the side

68:12

of my foot where your pinky is where my

68:13

pinky is so instead of running through

68:15

like this I run through like this puts

68:18

extra stress on my achilles tendon

68:20

changes my gate enough that it's tight

68:23

all up through the left side of my body

68:26

and my right um hip flexor is taking the

68:29

brunt of that that is a motion pattern

68:32

deficit that I know I have so if you

68:34

were predictably getting the same injury

68:36

all the single time it's probably due to

68:39

Something's too tight on one side

68:41

something's too weak on the other side

68:43

and if you get it evaluated you could

68:45

probably train it out of you you have

68:48

athletes and people that come you stand

68:50

on one leg to test something yeah what

68:52

is that do you want to see it yes yeah

68:54

let's do it

68:56

so to test whether we have muscle

68:58

imbalances that could cause injuries

69:00

when we run because I had said Runners

69:02

are very hurt athletes that I take care

69:04

of this is called the Trendelenburg sign

69:07

and it tells us whether your glute your

69:09

butt muscles are strong enough to keep

69:11

your pelvis straight and whether you're

69:13

strong enough to keep your knee from

69:15

falling into this position okay which is

69:17

called vagus so collect yourself we're

69:20

going to stand all stacked up on our

69:23

left knee my left knee yeah oh gosh yep

69:27

and then we're going to do some single

69:28

leg squats without falling

69:30

over so what happens is people drop

69:33

their hip and their knee Falls like this

69:37

it goes blop yeah a thousand steps a

69:41

mile so you can imagine if your knee's

69:43

like this a thousand steps a mile your

69:45

little kneecaps getting pulled off and

69:47

we can't balance we're getting our

69:49

balance a thousand steps of Mile so we

69:51

can train this let's do the other leg

69:54

engage sit single leg squat you look

69:56

like I'm drunk or something yep there

69:59

you go now you're

70:01

compensating but the goal in the mirror

70:03

is not to have the hip drop and not to

70:05

have the knee fall in I feel like this

70:07

one's way stronger and that's why it was

70:08

easier it it looks that way so that

70:10

means this glute this rear end glute is

70:13

stronger than that one that's the one

70:15

that always gets injured my left one yep

70:17

because it's not functioning as well and

70:19

it leaves this side unprotected so what

70:21

have I got to do so uh double leg squats

70:25

are good but single leg step UPS single

70:27

leg lunges as in like so if we had a

70:31

step we would be holding a we could

70:33

start with no weights like

70:37

this and you're tall you could start low

70:40

you could go up here I usually usually

70:41

use an 18 and then when you feel

70:44

comfortable and your hips not bouncing

70:47

up and down take your your we weight

70:49

your barbell and step up and step down

70:54

okay yep y right cuz it's Single Leg so

70:57

I'd have my weight and I'd be going like

71:00

this MH and then I step down step down

71:03

with the same

71:04

foot and what am I what am I doing here

71:06

I'm I I'm just you're strengthening one

71:09

side at a time okay because if you step

71:11

up if it and you're wobbly M then that's

71:14

what's happening when you're running

71:16

okay and so you can do step Downs too I

71:18

mean you can come this way and then come

71:22

like this okay yeah and then we do uh

71:26

there are lots of things like this a

71:28

good physio but if we're up here we can

71:30

do things like um hip hitches where you

71:33

put your leg down I am in heels today

71:36

but we go down like

71:37

this without going down like this yep

71:42

okay thank you so much let's get the

71:43

table back

71:44

in your gut and my gut is the home of

71:47

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71:49

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Amazon on the subject of OB it and

73:55

weight we talked last time really

73:57

fascinating thing that you said to me

73:58

which stayed with me is that the more

74:00

weight we're carrying the more harm it's

74:02

doing to our bones in a really

74:04

disproportionate way could you clarify

74:06

that again but also talk to me about

74:08

give me the case for keeping my body fat

74:11

down as I age so what we were talking

74:14

about is uh joint health yeah and the

74:18

fact that every bone if in your knee for

74:20

instance if your Fe if this is your

74:22

femur the end of every bone has a bumper

74:25

of cartilage cartilage is a matrix of

74:27

collagen fibers that has cells in it and

74:30

its entire job is to shock absorb so the

74:33

bones don't do so much of this bones are

74:35

pretty fragile but they Glide cartilage

74:39

has a in physics a coefficient of

74:42

friction that is less than ice so it's

74:44

smoother than ice it Glides right if

74:47

it's

74:48

perfect cartilage is very subject to the

74:52

forces of weight such that in our

74:54

Laboratories when we were doing

74:55

cartilage research and wanted to damage

74:57

cartilage all we had to do is drop a

74:59

marble on it so it doesn't take much so

75:02

if we're carrying around a lot of heavy

75:04

extra weight and we don't have the

75:06

muscles to support that instead of

75:08

muscles actually like a shock absorber

75:10

and protecting our cartilage we're

75:12

banging more now remember banging is

75:14

good for bones it's not good for

75:16

cartilage so we want to make sure that

75:19

we have a healthy weight so that we're

75:21

not exerting so much load because it's 7

75:24

to n we talked about last time 7 to n

75:27

times uh body weight pressure across the

75:30

joints and so that's why we want to

75:33

compose our body and have a body

75:36

composition not a weight a body

75:38

composition of of more muscle than at

75:42

aost tissue yeah this kind of goes back

75:44

to what we were saying earlier because

75:46

you can say these things but still

75:48

changes still far away from many many

75:50

people and I was just wondering in the

75:52

people that you've seen make radical

75:53

changes that you've worked with are

75:57

there key things that happen we talked a

75:58

little bit about someone hits Rock

76:00

Bottom they get a bad diagnosis they're

76:02

forced but is there is there anything

76:04

else that one can do to will themselves

76:07

to change to keeping a journal some kind

76:10

of exercise I think it's really helpful

76:12

to know as much about yourself as

76:14

possible so if I'm intaking someone into

76:17

a program we're going to build I don't I

76:20

weigh them but what's most important is

76:23

I do a body composition so that we can

76:25

go through step by step and say in your

76:27

current body you have I'm making these

76:30

numbers up 32% body fat you have very

76:34

little lean muscle so even though you

76:35

may be okay with the way you look in a

76:37

mirror you're skinny fat meaning you

76:40

have two little muscle and too much

76:42

adapost tissue and and we just and we

76:44

talk about all the things we've talked

76:46

about about why we need to build more

76:48

muscle but when you see those numbers

76:50

numbers don't lie nor are they judgments

76:53

but if you're just looking in the mirror

76:55

you may say oh that's okay or you may

76:57

hate the little belly roll but it's not

76:59

you don't hate it enough but when you

77:01

see that you have very little muscle

77:02

mass and a very high percentage of fat

77:06

those data alone are sometimes a

77:08

motivation and then if we know that

77:12

we're going to redo that test in three

77:15

months or six months and track changes

77:17

over time that can be an added motivator

77:20

besides tragedy data can be a motivator

77:24

wanting to feel like yourself again in

77:27

in women in midlife someone sometimes

77:29

just say I just want to feel like myself

77:31

again well we're different people after

77:34

our estrogen goes away and so it takes a

77:36

different kind of work to feel like

77:37

ourselves again but at the end of the

77:40

day so tools wise I think journals are

77:42

are helpful tracking uh keeping a record

77:45

of how you felt on a day what you did

77:47

that day cgms and stuff as well anything

77:50

that turns the lights on has been really

77:52

that's right data cgms are you you know

77:55

I learned what I was going to learn at 3

77:56

months but I've had it on for 18 months

77:58

just cuz that data Spurs me on like oh I

78:02

that was a really stressful o day my

78:04

sugar spiked up even though I wasn't

78:05

eating I must have been very high

78:07

cortisol I'm releasing so much from my

78:09

liver it's just informs me about the

78:11

inner workings of my body but also at

78:14

the end of the day you have to love

78:16

yourself enough Stephen and I can't make

78:19

you love yourself and I can't a number

78:21

of harassments in my office cannot make

78:24

make you value yourself enough to invest

78:27

in yourself daily and at the end of the

78:29

day that's what it's going to

78:31

take I've talked quite extensively on

78:33

this podcast about menopause it's really

78:36

fascinating to me I think in part

78:37

because I didn't even know what it was

78:39

yes even it a couple of years ago

78:41

probably a year and a half ago I had no

78:42

idea what it was what are some of the

78:45

pervasive myths about menopause that

78:47

people still need to sort of get

78:50

past despite everyone talking about it

78:52

despite you having lots of ation about

78:55

it I still find a lot of people who have

78:58

never heard of Perry

79:00

menopause which is the decade leading up

79:03

to the day of menopause which is 365

79:07

days after your last men menstrual cycle

79:09

on average in this country it's about

79:13

51 people have not heard of per

79:15

menopause they've never heard of hormone

79:18

replacement therapy and they don't know

79:20

what to do about it and they're ashamed

79:23

to talk about it because

79:25

somehow needing things in this country

79:28

if you're a

79:30

woman have gone unnoticed for instance

79:33

like oh I'm just going to suffer through

79:35

my mom never talked about it so I think

79:38

the myth that you have to suffer is a

79:40

myth there is more known now than

79:43

there's ever been about how using

79:45

lifestyle to feel better I always

79:48

encourage women to make their hormone

79:50

replacement decision based on science

79:51

and not fear and to make it early

79:55

how I I encourage my patients even in

79:58

the mid 40s to read the books watch the

80:02

podcasts identify a clinician so when

80:05

it's time for them to make their

80:07

decision they've got

80:08

everything um lined

80:11

up and you can take hormones while

80:13

you're still menstruating and there's no

80:15

reason not to in fact that's what birth

80:17

control is birth control is is 10 times

80:21

the dose of hormone replacement therapy

80:24

so

80:25

under careful supervision you can make

80:27

your decision very early what I want

80:30

people to do uh is educate themselves I

80:34

call it menopause literacy because we

80:36

have a very low level of menopause

80:38

literacy in this

80:40

country I want them to make their

80:42

hormone replacement decision

80:45

meaning am I going to go on them where

80:47

am I going to get them can I find a

80:50

clinician to help me number three I

80:52

would like them to as we talk talked

80:54

about

80:55

earlier build their unbreakable

80:58

lifestyle develop the habits early not

81:00

when they're in the throws of menopause

81:02

and feeling desperate but early of

81:04

lifting weights of cardio that includes

81:08

base training and Sprint intervals

81:11

anti-inflammatory nutrition early so

81:13

that it's just the way you live so that

81:17

when you're feeling so bad you're not

81:19

trying to learn all these things at

81:21

once and there is a significant link

81:23

between menopause and bone density

81:27

because you lose some of those critical

81:30

hormones like testosterone like estrogen

81:32

and testosterone so estrogen on

81:35

Bones acts to control the cell that

81:38

breaks down bones we talked about in

81:40

bone health there's a cell that breaks

81:42

down Bones called the osteoclast with a

81:44

c and a cell that builds bones with

81:47

called an

81:48

osteoblast estrogen helps control the

81:50

osteoclast so even in menopause when

81:55

there is no estrogen we're still

81:56

building bone but breaking down bone out

81:59

strips building bone so replacing

82:02

hormones helps rebalance bone breakdown

82:06

and Bone

82:09

rebuilding and if we lose our estrogen

82:13

around the time of this per menopause

82:16

menopause we can lose

82:17

15% of our bone density and if we don't

82:20

catch it because insurance only pays for

82:23

dexas scans when we're 6 5 Which is far

82:25

too late in my opinion we're behind the

82:27

eightball so I encourage everyone once

82:30

they start going through par menopause

82:31

to get a dexa scan whether they have to

82:33

pay for it at their gym save up their

82:35

coffee money it's worth knowing your

82:38

bone status what are some of the most um

82:42

obvious but pertinent muscular skeletal

82:46

syndromes of menopause I'm glad you

82:48

asked that in July my group and I

82:50

created a

82:51

nomenclature called the muscular

82:53

skeletal syndrome of menopause because

82:56

women were showing up in my

82:58

office saying things without prompting

83:02

because I I'm a doctor who listens I sit

83:04

down on a stool we have a conversation I

83:06

do not chart in front of you so

83:09

people talk to me and out of nowhere

83:12

women would say to me Doc I feel like

83:15

I'm falling

83:17

apart and I don't know what's going on

83:19

but I feel like I'm going crazy because

83:21

I've been told nothing's wrong with me

83:24

and I started noticing that more and

83:26

more as women started coming

83:28

in with their shoulders not moving which

83:31

is an entity called frozen shoulder and

83:34

so as I

83:35

started looking at this pattern and

83:38

reading the very few studies that were

83:40

done we've known for 30 years that the

83:43

incidence of arthritis inflammatory

83:46

arthritis in women after 50 is much

83:49

higher than inflammatory arthritis in

83:50

men we've known it for 30 years and as I

83:54

started researching remember how I said

83:56

earlier that every muscular skeletal

83:58

tissue is derived out of the same type

84:00

of stem cell the mesenchimal stem

84:03

cell all of those tissues muscle bone

84:07

tendon ligament

84:09

fat muscle Drive stem cells are all

84:13

sensitive to estrogen and without it

84:15

several things happen there's something

84:17

called arthralgia which is total body

84:20

pain meaning your body hurts so much

84:24

that you can't even get out of bed that

84:25

was one of the biggest things I had I'm

84:27

an athlete and I could barely get out of

84:29

bed because I was so

84:31

inflamed due to the lack of estrogen

84:33

estrogen is a huge anti-inflammatory

84:36

agent so I was totally inflamed my body

84:39

hurt that's called arthralgia women come

84:42

in and I'm not kidding they come in they

84:44

say my arm won't move literally it won't

84:47

move or I can't hook my bra that is due

84:50

to the inflammation of losing estrogen

84:53

in Asian cultures it's called the

84:54

50-year-old woman's shoulder because it

84:56

happens to 50-year old women it is a

84:58

sign of the inflammation of losing

85:01

estrogen we know about sarcopenia the

85:03

loss of lean muscle mass about 20% when

85:06

you lose your estrogen we've talked

85:08

about loss of bone density we have

85:10

increased incidence of tendon and

85:12

ligament problems Achilles tendon tennis

85:15

elbow patellar tendon because the

85:18

collagen fibers of Tenon and ligament

85:21

have estrogen receptors on them and so

85:23

everything starts to work less well

85:27

without the presence of estrogen so I

85:29

saw all of those things and we gathered

85:32

the world's data which isn't a lot a lot

85:35

more research needs to be done and we

85:37

gave it a nomenclature we called it and

85:39

published it as the muscul skeletal

85:42

syndrome of menac cause because I tell

85:44

you for sure Stephen if someone goes

85:46

into their doctor's office which in this

85:48

country is so restricted in the time

85:51

that we can spend and says I have this

85:54

and this and this and this and this six

85:55

things in 15 minutes it is difficult to

85:59

get through that but if someone comes

86:02

with a nomenclature of I think I have

86:05

the musculoskeletal syndrome of

86:07

menopause my arm doesn't move blah blah

86:10

blah immediately you don't have to go

86:13

through a differential diagnosis of 600

86:15

things you're like oh as a

86:17

doctor this paper on the

86:20

musculoskeletal syndrome of menopause

86:22

has currently been downloaded almost

86:24

300,000 times and to put that in

86:28

context some of the biggest journals in

86:30

the world medical journals in the world

86:32

documented they did a a survey of how

86:34

many times their best articles had been

86:36

downloaded the best scientific journals

86:40

their articles are downloaded about

86:41

10,000 times this muscular scal syndrome

86:45

of menopause has been downloaded nearly

86:47

300,000 and it's not because yes it's a

86:51

good paper the need is so great Stephen

86:54

to communicate what the heck is going on

86:57

with people that I made it open access

87:00

meaning you don't have to pay to get

87:01

this article and I encourage people to

87:05

Google it it'll come up number one to

87:07

print it to read it to give it to your

87:10

doctors so that they can understand that

87:12

you're highly inflamed that's why your

87:14

total body hurts that your shoulder

87:16

doesn't move because you're inflamed

87:19

that your knee hurts because you have

87:21

the arthritis of menopause and just to

87:24

build the understanding of what is

87:26

actually going on with people

87:29

fascinating I didn't mean 300,000

87:31

downloads I know it's amazing it's like

87:33

a New York Times bestseller bestseller

87:37

research paper 30,000 p over or

87:39

something crazy crazy yeah

87:41

congratulations well you know what

87:43

research is a team effort and and we all

87:46

work together but thank you it's needed

87:48

used a word there arthritis which we've

87:51

not talked about yet but but used it to

87:53

describe your big toe as well yes I did

87:55

what is causing arthritis I don't want

87:57

to get arthritis oh who does there are

87:59

there are two kinds of arthritis there's

88:00

an autoimmune meaning your body is

88:03

identifying yourself as not yourself and

88:06

that's called rheumatoid arthritis that

88:07

is very different than the way I used it

88:10

today which is osteoarthritis which is

88:13

wear and tear arthritis okay so wear and

88:16

te arthritis can happen through

88:18

thousands and thousands of repetition uh

88:21

on a joint uh we were talking earlier

88:23

about running it's a thousand steps a

88:25

mile it can happen due to trauma I have

88:28

a lot of I used to take care of the

88:30

University of Pittsburgh football team

88:32

and I had a lot of 20-year-olds with

88:33

knee arthritis because the impact was so

88:36

great as linemen hit each other that

88:39

they would wear out their cartilage so

88:42

wear in ter arthritis

88:44

osteoarthritis is loss of the cartilage

88:47

layer on the end of bone it causes

88:51

aching pain it causes swelling it causes

88:56

stiffness uh and then to the degree that

88:59

you have it we can treat you

89:02

conservatively through a variety of

89:05

ways or at the end of the road we can

89:07

replace your joints I want to just

89:09

circle back on we were talking there

89:11

about the collection of symptoms that

89:12

are associated with menopause and you

89:14

were talking about how arthritis is a is

89:16

a factor are you telling me that to

89:19

avoid the muscular skeletal symptoms of

89:22

menopause

89:24

I should be taking hormone replacement

89:26

therapy here's what I'm telling you I'm

89:29

telling you that

89:31

every musculoskeletal tissue has Alpha

89:35

and beta estrogen receptors we know that

89:38

when those sit empty you will manifest

89:41

some of the muscular skeletal syndrome

89:42

of menopause 80% of us

89:45

do what I'm telling you is

89:48

that estrogen sitting in those receptors

89:51

can prevent bone loss can prevent muscle

89:54

loss can decrease the inflammation of

89:56

arthralgia and frozen shoulder so

89:58

everyone gets to make their own

90:02

decision people are thinking beings they

90:05

have agency they get to make that

90:07

decision to get out of pain and to

90:10

prevent the musculoskeletal syndrome of

90:12

menopause based on science and not

90:17

fear one of the um one of the things I'm

90:20

a little bit concerned about these days

90:22

is back pain yeah lower back pain in

90:25

particular um I read that lower back

90:26

pain is the single leading cause of

90:28

disability globally significantly

90:29

affecting individual's quality of life

90:31

and productivity which was published on

90:33

the World Health Organization yeah

90:36

article in 2020 lower back pain affected

90:40

69 million people globally and its

90:44

prevalence is increasing due to a number

90:46

of different factors one being aging but

90:48

also I just think generally how we're

90:50

living more sedentary lives and sitting

90:52

on these chairs and stuff like that mhm

90:54

back pain yeah common thing only seems

90:56

to exist in the Western World I had

90:58

someone come here from the who studied

90:59

the hadza tribe in Africa and they don't

91:02

have back pain there yeah how do they

91:04

live not like this right they squat yes

91:06

they don't have chairs

91:08

yes well back pain is endemic in our

91:12

population due to our lifestyle we're

91:13

sitting here for several hours I'm

91:15

probably sitting like this all hunched

91:17

over at some points our our cores are

91:20

relaxed we're not our our front cores

91:23

are relaxed relaxed our our lower back

91:26

is relaxed there's no stimulus to keep

91:29

our core strong sitting in a chair and

91:31

we do this 10 hours a day at least

91:34

right that's number one number two then

91:38

70% of people do no meaningful exercise

91:40

any time of the week so we never rebuild

91:43

it so we get low back pain due to muscle

91:47

weakness and another reason we get low

91:50

back pain particularly in women or very

91:53

elderly men is compression of our

91:54

vertebrae compression fractures of our

91:57

spine that can be very painful it

91:59

presents as low back pain I want to

92:02

differentiate for people listening the

92:03

difference between low back pain and and

92:06

nerve impingement that needs surgery low

92:09

back pain is that aching in your low

92:11

back the

92:13

stiffness when you go to a doctor with

92:15

low back pain there should be telling

92:18

you how to get stronger sending you for

92:21

physical therapy to stop smoking if

92:23

you're smoking CU that poisons bones

92:25

right all the lifestyle

92:27

things if you have pain starting in your

92:30

back but shooting down your leg like

92:33

electricity down the back of your leg

92:36

like literally think about how lightning

92:38

would feel that is because a nerve is

92:40

being impinged as it comes out of your

92:42

spinal cord that is something that needs

92:46

to be examined and looked at but I just

92:48

want to differentiate that because a lot

92:50

of people um mistake the tube to and a

92:55

lot I think it was 80% of westerners

92:57

will experience lower back pain and it

92:59

got me thinking about standing desks and

93:02

things like that do you advise people to

93:03

use standing desks I do and walking

93:05

treadmills um because there's so much

93:08

work that we do during the days that

93:09

isn't deep work we're emptying out our

93:11

email we're returning some phone calls

93:13

we're doing the less heavy brain heavy

93:17

parts of our job all can be done

93:19

standing or I've encouraged uh groups of

93:23

people that I work with to hold their

93:24

meetings doing wall squats just don't

93:27

sit at the board table pull up a wall

93:29

everybody's squat better be a pretty

93:31

quick meeting because that that takes a

93:33

lot of strength but to build in that

93:36

kind of Mobility the only time we really

93:38

need to sit is when we're solving World

93:41

Peace yeah the rest of it we can stand

93:44

and in fact Studies have shown that if

93:46

we're trying to learn something it's

93:48

better to be moving as we learn because

93:51

the kinetic energy of learning is better

93:53

for our brain

93:54

for instance I used an

93:56

example uh yesterday actually when I I

93:59

was teaching people how to time manage

94:02

and I said when I'm listening to long

94:04

form podcasts like this I can't sit for

94:07

three hours but I can walk and listen

94:10

and I retain more for instance

94:14

so that that been proven that if we're

94:16

in exercise we retain more in terms of

94:19

studying oh okay you've done a lot of

94:21

studies they're so fascinating H have

94:24

you got a favorite the very first one we

94:27

did on Master's athletes answering the

94:30

question at what age do we really slow

94:33

down because if you believe

94:36

Hallmark and all the uh rest in peace

94:39

balloons that go around on your 40th or

94:41

50 birthday slowing down is an

94:44

inevitable part of aging but the fact of

94:47

the matter is and our study showed

94:50

that when I looked at track and field

94:53

ath in every race from 100 m to 10,000 M

94:57

and I looked at the top eight finishes

94:59

in every age group in every race that we

95:03

do not significantly slow down until

95:07

we're past

95:08

70 so between 50 and

95:11

70 the guy who won the one mile race

95:16

finished it in four minutes and 34

95:18

seconds the same year of the study the

95:21

kid that won the high school mile race

95:23

did it in four minutes and 17 seconds

95:26

the 70 70-year-old who won the one mile

95:28

race did it in a little less than 7

95:31

minutes it just shows you that if we're

95:34

slowing down dramatically before our 70s

95:37

we've either decided not to train so

95:39

hard we're just not trying anymore we've

95:41

been terribly injured right and we can't

95:45

but it's not because of biology because

95:47

of psychology exactly no light bulb goes

95:50

off we think though we think that when

95:53

we experience that first twinge that

95:54

first pain we start to get a little bit

95:56

tied we think it's natural so we kind of

95:58

relent to it we just give in and then

96:00

that's that slow spiral downwards into a

96:02

lifestyle which becomes self-fulfilling

96:04

I guess we stop trying hard we stop

96:06

playing hard because we stop trying hard

96:08

because we think it's inevitable we

96:10

think no aging is inevitable how we age

96:13

is is up to us you're working on a book

96:16

aren't you you've just handed in the

96:17

manuscript for we're very very excited

96:19

about this book unbreakable unbreakable

96:22

go strong live long age with power and

96:26

it really picks up the conversation of

96:28

aging and Longevity that I've been

96:30

talking about for a long time but really

96:33

focuses on the longevity of

96:36

women so the book is framed around the

96:40

pillars of Aging which I call time bombs

96:44

the time bomb of metabolic dysfunction

96:47

uh the time bomb that we think means our

96:49

DNA as our destiny which it is not we

96:51

can modify ourselves and several others

96:55

and really explain the science of what's

96:57

going on and that aging is not an

96:58

inevitable decline from Vitality to

97:00

Frailty unless we cop to that attitude

97:03

right and then the second part of the

97:05

book lays out a lifestyle that I call

97:08

unbreakable it's about muscle it's a

97:10

bone it's about nutrition but the most a

97:12

very important part is what you just

97:14

said it's about attitude and mindset and

97:18

so I help

97:20

people set standards and goals for for

97:23

what they want based on their values if

97:25

I didn't Value Independence if I didn't

97:28

value having my brain till the very end

97:31

and all the other things that I

97:34

value then my goals would be uninformed

97:37

I could say oh I want to run a marathon

97:38

at 80 but that's not enough unless it's

97:41

connected to my values and then further

97:44

along we talk about building resilience

97:47

because brain resilience can be built in

97:49

the same way that skeletal resilience

97:51

can and I believe it takes both both of

97:53

those things to progress and to age with

97:57

power and then the final sections of

98:00

this book really take us to the next

98:02

level how do we now that we've optimized

98:04

our health and decided that we are not

98:09

the

98:10

victims of time I don't believe that I

98:13

believe we

98:15

can shape our future how what do we do

98:18

for Peak Performance how do we continue

98:20

to squeeze performance out and what are

98:22

the cool techniqu technologies that can

98:24

help us I'm very very excited yay can we

98:27

pre-order it yet uh not yet but you can

98:29

get on my wait list on my website okay

98:32

I'll link that below for anyone that's

98:33

Keen to get that book I I'll be on that

98:35

list as well I'll give you one is there

98:38

anything else that we should have talked

98:39

about that we haven't Dr

98:41

vunda last week I was uh speaking at the

98:45

American Diabetes Association and

98:48

talking about midlife and menopause

98:50

which you and I have talked about and

98:51

all the metabolic changes that go on

98:53

when estrogen walks out the door and

98:55

we've already talked today about

98:58

pre-diabetes and how we need to put on a

99:00

big alarm because of all the metabolic

99:02

changes that will lead to diabetes and

99:04

Alzheimer's but when I look at those two

99:06

things separately per menopause and all

99:08

the metabolic changes and the lipid

99:10

changes and the fat distribution and the

99:12

insulin insensitivity and pre-diabetes

99:15

they are nearly identical and what we

99:18

know is that this is another alarm to

99:22

sound if we have not paid attention in

99:24

the critical decade of our lives and

99:27

become pre-diabetic and then are a woman

99:29

and lose our estrogen it compounds the

99:32

normal metabolic changes that happen

99:34

with insulin resistance to the loss of

99:37

estrogen and after menopause women have

99:40

more diabetes and therefore more

99:42

Alzheimer's and so if I can back all

99:45

this up and start people thinking about

99:47

it when we're 35 that is work worth

99:49

doing that's exactly what you're doing

99:52

it's exactly what you're doing I think

99:54

you know the reason I'm so compelled by

99:55

menopause as well a secondary reason is

99:57

because I have so many wonderful women

99:58

in my life incl including my partner who

100:00

yeah might not be as fortunate to be

100:01

exposed to all the information that I

100:03

get exposed to by doing this so many of

100:05

the questions I'm asking you almost pre-

100:08

preparing me to be a supporting act in

100:12

her in her life she's what 32 now so you

100:15

know critical critical years you know

100:17

what Stephen if I could get more men to

100:19

take the attitude that you've just

100:21

expressed to have the Curiosity it to

100:23

learn about the changes in midlife women

100:26

and not only bodily changes but but

100:30

attitudinal and the sexuality changes I

100:33

think we could save a lot of marriages

100:34

but I find that there is for the lack of

100:38

knowledge there is amongst the women

100:39

there is even less knowledge among the

100:41

men but if it's a partnership so I think

100:45

your attitude and curiosity is is

100:47

laudable because I think we could save a

100:49

lot of relationships if everyone felt

100:51

that way yeah cuz if for me it has

100:54

created a ton of empathy MH and with

100:56

empathy you approach challenges

100:59

differently with a different perspective

101:00

yeah and there's less blame and there's

101:02

more yeah I think supporting um

101:05

encouragement so that's really why I

101:07

think it's important as well for men to

101:08

understand these things

101:10

because when you start noticing

101:13

differences maybe in someone in way she

101:15

she's feeling or your mother or yeah

101:17

grandmother or even your

101:19

daughters you might not be some of those

101:22

you know naive doctors who think

101:24

someone's losing their mind or that

101:25

they're just being different or it's

101:27

their personality and you might

101:28

understand that there's something deeper

101:29

going on um and also something that's at

101:32

least in part you can do something about

101:35

absolutely which I think is the most

101:37

important conclusive point we have a

101:39

closing tradition on this podcast where

101:40

the last guest leaves a question for the

101:42

next guest with not knowing who they're

101:43

leaving it for and the question left for

101:45

you is how do you know when is

101:48

enough I think how you know when it's

101:51

enough when it becomes if it pertains to

101:54

work or striving for something or is

101:59

when you don't love it anymore when it

102:01

becomes a grind and you don't love

102:04

it that's when it's enough because it's

102:06

not feeding

102:08

you

102:12

amen Dr Vite thank you so much for the

102:15

work that you do um you're such a star

102:18

and I think everybody should go follow

102:19

you on Instagram because you built an

102:21

incredible community over on Instagram

102:22

where you give away so much of this

102:24

knowledge absolutely free of charge but

102:26

I also think everybody should go to your

102:28

website thank you they should buy this

102:30

book I know this book is um maybe they

102:32

should just get on the wait list for the

102:33

upcoming book as well unbreakable

102:35

unbreakable um and they can get on that

102:36

weight list on your website right now

102:38

yes they can join your Instagram

102:39

Community which I think is phenomenal

102:41

it's so wonderful to see yeah um how

102:44

because you know usually people have a

102:45

following but I really feel like you

102:47

have a community yes I see it in the

102:49

comment sections I see that people are

102:50

really really engaged and there as you

102:52

saw from the amount of people that

102:54

downloaded that paper that you published

102:56

there's a real thirst and hunger for

102:59

this information and I get so many

103:01

messages when from the last conversation

103:03

we had yeah but from these conversations

103:05

generally about from women from their

103:09

husbands who are so thankful for you oh

103:12

like so thankful it's you know because I

103:13

have lots of conversations about lots of

103:15

things but this particular conversation

103:18

provokes a certain type of energy that

103:19

is very atypical oh you know what I mean

103:22

you understand it because you feel it

103:23

every day but I really feel it as well

103:25

so thank you for doing the work that you

103:26

do and for turning the lights on for so

103:28

many people that are living in the

103:30

darkness as it relates to information

103:33

and that information is no doubt

103:35

undoubtedly saving many millions of

103:36

people's lives I hope so and that's work

103:39

worth we're doing so thank you so much

103:40

Dr vond thank you this has always blown

103:43

my mind a little bit 53% of you that

103:45

listen to the show regularly haven't yet

103:47

subscribed to the show so could I ask

103:49

you for a favor if you like the show and

103:51

you like what we do here and you want to

103:52

support us the free simple way that you

103:54

can do just that is by hitting the

103:55

Subscribe button and my commitment to

103:57

you is if you do that then I'll do

103:59

everything in my power me and my team to

104:01

make sure that this show is better for

104:02

you every single week we'll listen to

104:04

your feedback we'll find the guests that

104:06

you want me to speak to and we'll

104:07

continue to do what we do thank you so

104:09

much some of the most successful

104:11

fascinating and insightful people in the

104:12

world have sat across from me at this

104:14

table and at the end of every

104:15

conversation I asked them to leave a

104:17

question behind in the famous Diary of a

104:20

CEO and it's a question designed to

104:21

spark the kind of ation that matter most

104:24

the kind of conversations that can

104:25

change your life we then take those

104:27

questions and we put them on these cards

104:30

on every single card you can see the

104:33

person who left the question the

104:36

question they asked and on the other

104:37

side if you scan that barcode you can

104:39

see who answered it next something I

104:41

know a lot of you have wanted to know

104:43

and the only way to find out is by

104:45

getting yourself some conversation cards

104:47

which you can play at home with friends

104:48

and family at work with colleagues and

104:50

also with total strangers on holiday

104:52

I'll put link to the conversation cards

104:54

in the description below and you can get

104:55

yours at the diary.com

104:59

[Music]

Interactive Summary

In this video, Dr. Vonda Wright, a renowned orthopedic surgeon and longevity expert, explains the critical importance of maintaining bone and muscle health throughout life. She emphasizes that aging is not an inevitable decline into frailty but a process that can be managed through a lifestyle she calls 'unbreakable,' which focuses on nutrition, resistance training, and mindset. Dr. Wright discusses the specific challenges faced by women during menopause, such as the loss of estrogen affecting bone density and musculoskeletal tissues, and provides actionable advice on how to build resilience and vitality regardless of age.

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