Dr Leo Happel Interview
616 segments
Cherie Young: Hello, my name is Cherie Young. Today is September
3rd, 2025 and I'm interviewing Dr Leo Happel on behalf of the
ASET Historical Advisory Committee. Thank you for being
with us today, Dr Happel.
Dr. Leo Happel: My pleasure.
Cherie Young: Great. So, Dr Happel, you are currently
retired, correct?
Dr. Leo Happel: Retired in quotes, as I was explaining a
little bit earlier, when you when you are in academic
medicine and you teach students, your students always feel like
they have the prerogative of calling you when it's necessary,
when they need something explained. And so I have a lot
of surgeons that I had no contact with previously who call
me and ask me questions and try to get me to explain what they
are seeing in the operating room. This is becoming much more
common now since my former head of neurosurgery, Dr David Klein,
passed away about six months ago, and so all the calls that
used to go to him now come to me, and sometimes it gets really
tough.
Cherie Young: Yep, so there's no such thing as retirement, right?
Dr. Leo Happel: Exactly, except that you don't get paid anymore.
Cherie Young: Right? Where did you receive your credentials for
intraoperative monitoring?
Dr. Leo Happel: I received my credentials when I was hired by
LSU medical school. I was hired by Dr Richard Patterson, who was
then the head of neurology, and he appointed me an Assistant
Professor of Neurology, even though I am a PhD, not an MD.
And so as a member of the faculty of the neurology
department that automatically gave me credentials at Charity
Hospital New Orleans. Charity Hospital, New Orleans was a
teaching hospital, and so the teaching faculty came from both
Tulane and LSU medical schools, the clinical departments. If you
had a clinical appointment, you automatically had the privilege
of seeing patients at Charity Hospital and performing testing
on them, and that was how my credentials got started. I had
to go through the process of acquiring other credentials. I
had to show proof of malpractice insurance, because you can't do
anything clinical at Charity Hospital unless you had
malpractice insurance. I had to go through training in basic
life support, because as a clinical faculty member, BLS
credentialing was required. So I had to show proof of training in
CPR. I had to be tuberculosis vaccinated. And with those
credentials, added to my academic credentials, I was
approved for seeing patients at Charity Hospital,
Cherie Young: Very good. And what drew you to evoked
potentials in intraoperative monitoring? How did you get into
that specific notch in diagnostic testing?
Dr. Leo Happel: I guess I have always been an electronics geek,
and as an electronics geek, when I was in graduate school, I
familiarized myself with a lot of electronic equipment and
basically did research in evoked potentials using the
instrumentation that I had familiarized myself with.
Cherie Young: Very good. So this wasn't very popular when you
started your career? You're one of the original pioneers,
correct?
Dr. Leo Happel: It was fundamentally nonexistent, and
the reason it didn't exist is there was no instrumentation
that was in one box. You couldn't go to the company
Nicolet because that didn't exist. You couldn't go to any of
the other vendors of evoked potential machines to buy a
machine, because they didn't exist. So what was necessary was
to assemble a cart with all of the appropriate equipment. I had
some GRASS amplifiers, and the GRASS amplifiers were
particularly good for two reasons. Number one, these
amplifiers had a very rapid recovery time, and so whenever
they whenever the instrumentation was smacked by a
large artifact like the electro surgical unit in the surgeon's
hand, these amplifiers would recover very quickly. And
another feature that these amplifiers had was they were
optically isolated, so there was no grounding associated with the
amplifier systems. And this was extremely important, especially
at Charity Hospital New Orleans, because Charity Hospital New
Orleans was a very old building, and all of the electrical wiring
in this building was not electrically isolated like it is
in all of the operating rooms today.
Cherie Young: Wow.
Dr. Leo Happel: So the optically isolated amplifiers helped a
lot. In addition, I had some GRASS stimulators, and the GRASS
stimulators were also optically isolated, and that precluded the
necessity for grounding. Grounding was a real problem in
the early days of neuromonitoring, because one of
the terrible things that would occur was the creation of a
ground loop. And in order to try to avoid ground loops, I
proposed something called Happel's law. And I don't know
if you remember Happel's Law. Happel's Law was "never, ever
attach more than one ground to a patient, it is never proper
technique". Anytime a patient has more than one ground on
their body, it is possible for their body to become involved in
an electrical current path that is part of a ground loop and
electrical burns from the operating room were relatively
common in the early 1970s.
Cherie Young: Wow. So we've overcome a lot of challenges
with our equipment these days. Wouldn't you say?
Dr. Leo Happel: Absolutely, the equipment manufacturers have
really done a great deal for technologists who actually do
the actual work. The inclusion of optical isolation in both
amplifier systems and stimulator systems really precludes the
possibility of ground loops. And so that is a huge help for us,
and takes away a lot of the risk associated with working in the
operating room. Operating rooms are intrinsically high risk
environments. They are very high electrical noise environments,
and they present us with lots and lots of problems. One of the
problems I had with working at Charity Hospital was the
operating rooms there were extraordinarily small. These
rooms were no more than 10 feet by 10 feet. And anytime you
start packing in a lot of equipment, the room just
disappears very quickly. I remember walking into another
hospital and walking into an operating room suite and looking
at the operating room and marveling at how big this
operating room was, and the operating room there got to be
very small by the time you put an EEG machine, stimulators, an
X-ray C arm, and all of the trays of instruments that the
surgeons needed by the time you put all that in the room, the
room got suddenly very, very small.
Cherie Young: Oh, my goodness. You've obviously created an
environment to test and record evoked potentials in the
operating room. Who would you say was the first manufacturer
of this equipment?
Dr. Leo Happel: The first manufacturer of the computer
that I use was a company called Fabritech, and Fabritech made a
computer of average transients, and that's what we needed to
have to do, the computer averaging that we do in
monitoring. Fabritech was a company that was later purchased
by Nicolet, and so it later bore the Nicolet name, but it was
nevertheless the same company.
Cherie Young: Okay, I remember back in the day a Tektronix. Was
that a computer you had built?
Dr. Leo Happel: Tektronix was a display. Tektronix is a
manufacturer of oscilloscopes. And so when I did surgical
monitoring, not just to do for spine surgery or brain surgery,
but for peripheral nerve surgery as well, the Tektronix became
the principal source of amplification and display.
Tektronix is a paragon name. Tektronix is a top of the line
oscilloscope and top of the line manufacturer, and this was
absolutely necessary to deal with all of the electronic
problems that we would encounter in the operating room. I have to
go back a few steps. I started working at Charity Hospital, not
in the operating room, but in a program of research that the
neurology department was conducting. The Department of
Neurology was trying to study the development of the human
brain, and the way they did that was recording evoked potentials
of neonates and then following those neonates over a period of
about eight years and watching the development of evoked
potentials as the brain developed.
Cherie Young: Wow. Very interesting.
Who would you say are some of your early mentors and earliest
influences in your career?
Dr. Leo Happel: This is kind of interesting. I'm glad you said
early influencers, because there were no real mentors. There was
nobody who had real expertise in operative monitoring. Some of
the people who were the early groundbreakers, there was a
fellow by the name of Augie Mohler. Augie Mohler, was
particularly good in the area of brain stem auditory evoked
potentials, and this is something that he performed
during the removal of acoustic neuromas, and he was able to
tell the surgeons what was happening to the point where he
dramatically improved the outcomes of brain stem auditory
evoked potential testing during acoustic neuroma removal. I
would like to mention as a learning issue here, to this
day, many people feel that if someone has an acoustic neuroma
in, let's say, their left ear, there is no reason to do
brainstem auditory evoked potential testing on their left
ear, and they just leave all that off, and they only do the
right ear to measure what's happening in the right
brainstem. And that's not really good technique. And the reason
for that is, when a person is deaf from an acoustic neuroma,
most of the time they still maintain a wave one of the
brainstem auditory evoked potential. Wave one of the
brainstem auditory evoked potential originates in the
distal eighth nerve. If that eighth nerve action potential is
still present, it indicates that the arterial blood supply to the
eighth nerve and to the cochlea is still intact. The blood
supply to the Cochlear artery comes through a blood vessel
that we call AICA, A, I, C, A, anterior, inferior cerebellar
artery. And this artery supplies several things in the brainstem
that are very much important. So it's still a good idea, even
though a patient is deaf in one ear due to an acoustic neuroma,
it's still a good idea to do the brainstem auditory evoked
potential testing on that ear, because it will still tell you
something about the blood supply to the brainstem.
Cherie Young: Right.
So really, when you started, there was no training program.
You did the training with physicians on personal nerve and
moved over into evoked potentials and intraoperative
monitoring. Where do you see us going in the future?
Dr. Leo Happel: Wow, that is a really tough question to answer.
Cherie Young: Certainly, we've come a long way from where you
started.
Dr. Leo Happel: One of the problems with neuromonitoring is
that it gets to be expensive. The equipment is expensive, the
personnel required to do it gets to be expensive. One would think
that it would be very easy for a single individual to bring the
equipment in the operating room and record evoked potentials
from a patient who is under anesthesia. It doesn't work out
to be quite that easy, and the reason for that is the surgeons
use some equipment that introduces vast amounts of
artifact in the records. And if there is one thing that a
computer system does not like, it's artifact. Transients that
are presented to the equipment doing evoked potentials creates
a noise problem that is so bad that it destroys the computer's
ability to demonstrate the evoked potential. So we usually
have to have two people in the operating room, one person
watching what the surgeon is doing. And I remember that the
early techs that worked with me would stand by me and stand up
tall enough that they could see over the drapes and see what the
surgeon was doing. And when the surgeon got ready to use the
bovy, the electro surgical machine, I'd get a tap on the
head, and I could quickly turn the inputs off, so that this did
not get into the computer and mess up the cumulative average
of what was going on. So all of this adds to the expense. And if
there's one thing that the medical insurance companies do
not like now, it's expenses, and so they try to cut back on
costs. And unfortunately, one of the things that's happening
right now is there are many insurers who designate that they
will not cover operative monitoring, even though
operative monitoring has clearly demonstrated that it improves
the outcome of particular surgeries. This happened first
with the brainstem auditory evoked potentials and acoustic
neuromas. When neuro monitoring was used in the case of removal
of an acoustic neuroma, the outcome statistics was so much
better than if monitoring was not used that some societies
like the American Academy of Neurology came out with a
position statement that said, if you'd removed an acoustic
neuroma without using auditory monitoring, you were practicing
substandard medicine. And got to be a very profound issue for a
long time, and to this day, most ENTs will use monitoring in the
case of acoustic neuroma removal.
Cherie Young: Scientific knowledge has certainly changed
in our field. What do you think were some of the big
breakthroughs, because you've seen it all starting from the
beginning. What do you think is one of our biggest
breakthroughs?
Dr. Leo Happel: One of our biggest improvements? The bottom
line and the bottom line is outcomes are better because of
neuromonitoring and it's hard to put a price on an improved
outcome, and that's why we have to argue with insurance
companies many times in order to get them to reimburse. We had an
issue once later on in my monitoring career, when there
was an insurance company that said, "Well, we're simply not
going to pay for it. If you want to do it, that's fine, but we're
simply not going to pay for it". And that put me in an awkward
position. I had to go to the surgeons and tell the surgeons,
look, I can't do this for free. This costs a considerable amount
of money, so I'm going to have to stop monitoring if insurance
is not going to reimburse for this. And so then the surgeons
said, "Well, I can't do the surgery without this". So he
would go to the administrator of the hospital, and he would tell
the administrator of the hospital, we're not going to be
able to do this kind of surgery. And the hospital would come back
and say, "Oh, well, but that's a very common procedure, and we
encounter this pathology often, and so we have to have you do
the procedure". And so we said, "Well, how can we arrange this"?
The hospital said, "Well, we will pay for the
neuralmonitoring by contract. We will contract with people who do
neuromonitoring and get them to perform the neuromonitoring, and
we will pay for that and the hospital at the end of the year
has a financial facility that they can turn to and things that
they are not reimbursed for they can charge off to various
governmental agencies. And so we're back in the situation
where we have the ability to finance neuromonitoring. And I
think most people would choose to use it because of the
statistically improved outcomes of surgeries that are monitored
compared to those that are not.
Cherie Young: That's correct. That's why we do what we do,
better patient outcomes, right?
Dr. Leo Happel: That's the bottom line.
Cherie Young: What would you say you're most proud of in your
professional life?
Dr. Leo Happel: The thing that I'm most proud of? I'm proud of
the teaching that the societies associated with neuromonitoring,
like ASNM, the teaching that those societies do. The
credentialing that the American Board of Neurophysiologic
Monitoring does, that basically indicates the person that's
doing this neuromonitoring is adequately trained. That's what
I'm most proud of, that we have created a plane of expertise,
and this plane of expertise can now be certified.
Cherie Young: Right, and you were a pioneer in the
development of some of these programs, like what we know as
ASNM today started out as...
Dr. Leo Happel: American Society of Evoked Potential Monitoring.
ASEPM. That's how it started out. That's the society that
first started off. And as the society evolved, they changed
its name to ASNM. And yes, I was a founding member of that
society. I was also a founding member of the American Board of
Neurophysiologic Monitoring, and I'm proud that I was able to do
that, and that we were able to examine people and certify that
indeed they had an adequate knowledge base to be doing
operative monitoring. Those were very good things to have done.
Cherie Young: Absolutely. What do you think was the best piece
of advice that you've ever received?
Dr. Leo Happel: Keep your eyes open and your ear to the ground.
Not the electrical ground, but... I had an unusual
opportunity in my career at LSU. When I was in the Department of
Neurology at LSU, there was research going on at the Delta
Regional Primate Center in Covington, Louisiana, and once a
week, I would go over there with either Dr Hector LeBlanc, Sonny
LeBlanc, or Roger Smith. And we had research going on primates
over there, and I had the opportunity to actually do some
of the surgery on the spinal cord of primates myself. This
gave me an opportunity to actually watch what was
happening to the blood vessels as I worked on the spinal cord,
and I gained a very healthy respect for the phenomenon of
vasospasm. When you mechanically stimulate blood vessels, you can
cause the smooth muscle of those blood vessels to constrict, and
that shuts down the blood vessels. And I was very much
sure that this same thing was happening when spine surgery was
being done on human subjects. As a consequence of that, I learned
my first principle of if the evoked potential monitoring
tells me something bad is happening, I will turn to the
anesthetist and ask them to raise the blood pressure. That
elevation of the blood pressure helps to prevent or reduce the
amount of vasospasm that occurs as a consequence of manipulation
of the blood vessels of the spinal cord. So that got to be a
very common thesis, and I think most people today will do the
exact same thing if they're in a surgical procedure, and during
that surgical procedure on the spine, the evoked potential
monitoring is changed. The first instinct that they have is to
raise the blood pressure and see if they can get the function to
return to what baseline was.
Cherie Young: If you were given the chance to interview anyone,
who would you choose in the field, to interview?
Dr. Leo Happel: One of the very authoritative people in
monitoring acoustic neuroma resection was Augie Mohler, and
unfortunately, Augie Mohler has passed away now, and he's not
available for an interview, but he was a very authoritative
figure, and his knowledge of neuroanatomy and neurophysiology
associated with the auditory system was very comprehensive,
so he would be a good person to learn from.
Cherie Young: Yes, and thank goodness we have his books with
all his stuff.
Dr. Leo Happel: Yes, we do have his book at least. And his book
is still very authoritative and still commonly used as a
referral point.
Cherie Young: So it's hard for me to believe, as you taught me
IOM, I was one of Happel's girls. I can't imagine you doing
anything else in your life, but if you wouldn't have gone into
evoked potential intraoperative monitoring, what profession
would you have chosen?
Dr. Leo Happel: Maybe I could have become an itinerant ukulele
stringer or something like that. I don't know what I would have
done. I had all of the background in electronics, in
physiology. My interest was in spinal cord function. And when I
was presented with the opportunity to join the faculty
at LSU and go into this area, with no reservations I jumped at
the chance.
Cherie Young: And you've done a wonderful job. You've taught so
many. What was your PhD in?
Dr. Leo Happel: My PhD was in neurophysiology. After I came to
LSU, I was only at LSU doing evoked potential recordings for
a period of about three months when the head of the
neurosurgery department, Dr David Klein, noticed what I was
doing and realized that I could help him out a lot. And so he
went to the head of the neurology department and told Dr
Patterson, "I want him in my department too. So I'm going to
make him 30% neurosurgery and 60% neurology". And so I got to
work with Dr David Klein, who was a world authority in
peripheral nerve surgery. I started doing a huge amount of
monitoring peripheral nerve function during neurosurgery for
peripheral nerve injury. Dr Klein passed away, I guess,
about eight months ago, and before he passed away, we tried
to put a comprehensive review of what we had done over the course
of 40 years monitoring peripheral nerve surgeries, and
the numbers that we came up with just blew me away. Over the
course of 40 years, we recorded data from 27,000 peripheral
nerve injuries. It made me realize why I got so tired. We
did it a lot, and some of these surgeries would last for long
periods of time. Dr Klein was particularly motivated in and
interested in surgery to the brachial plexus. Those surgery
procedures for brachial plexus injury would often last 18 to 20
hours, and we would be in the operating room for 18 to 20
hours recording peripheral nerve activity as he evaluated
different components of the brachial plexus. We had ample
pathologic material. The city of New Orleans had a very active
chapter of the Knife and Gun Club, and so as a consequence of
that, peripheral nerve injuries, especially to the brachial
plexus, were quite common and we did so many of those.
Cherie Young: I also want to ask you, how did that evolve into
spinal monitoring?
Dr. Leo Happel: I came to LSU in 1970 and so I got involved with
doing evoked potential recordings in the collaborative
Child Development Program and with teaching EEG techs. And I
did that for quite a few years, until finally, Dr Andrew King
asked me if I could do evoked potential recordings during
spine surgery. And I said, "Yeah, I think we can do that".
And we did one case at Charity Hospital, and the outcome from
this case was particularly good. This was a young man who had a
severe kyphosis, and during his correction of this kyphosis, we
lost all spinal cord function. When I told him that he was
really upset, and so the only thing he could think of to do
was to release the correction that he had placed on this young
man's spine. And when he released the correction,
instantly, spinal cord function returned. And so he put some
correction back, but not as much as he had originally, and the
spinal cord function was maintained. And the bottom line
of this case was, when the patient woke up, he was capable
of walking, using his legs, his spinal cord worked just fine. So
Dr King then asked me, "Well can we do this at Children's
Hospital?" And so I said, "Well, you know, I'm not credentialed
at Children's Hospital, but I have my credentials at Charity
Hospital, and we'll see what we can do." At that time, the
medical director of Children's Hospital was an
anesthesiologist, Dr John Heaton. Dr Heaton was a very
imaginative guy and a very forward looking guy, and he
said, "Yeah, let's see what we can do here". And so the only
way I could get on the staff of Children's Hospital was to be
hired by Children's Hospital as a contract employee under the
direct supervision of Dr Heaton, and this is how it came to pass.
So we started doing operative monitoring on the big spine
cases, on some of the brain stem cases, some of the neurosurgical
cases, and that's how neuromonitoring got started at
Children's Hospital. Over the course of many years, Dr King
and I have worked together, and we have many instances where we
have been able to identify an evolving problem that was highly
correctable, which we corrected with the outcome of a good
result from the surgery. And so I have to thank Dr King for his
efforts in getting me to work at Children's Hospital.
Cherie Young: So you were not only neurology, neurosurgery,
now you were orthopedics too.
Dr. Leo Happel: That's right, I actually got to do a lot of
orthopedic cases. And some of the orthopedic cases even
expanded beyond spine. During cases of hip replacement, it was
necessary to disarticulate the hip joint. And the orthopedists
who were doing that noticed that there was a lot of incidents of
peripheral nerve injury when the sciatic nerve was extracted and
pulled on to dislocate the hip joint, often it created an
injury to the sciatic nerve, and yes, we can monitor for that. So
that became one of the procedures that we would
frequently monitor. I would add not only orthopedics to what we
monitored, but the urologists got real interested in what we
were doing, and wanted to know, could we monitor from pelvic
floor nerves, because they had a lot of incidents of pelvic nerve
injury in the pelvic floor and so we started doing that. And as
we did that, the urologists actually got their own system
going, and they had their own people and their own equipment
to monitor urologic function during pelvic floor surgeries.
So it grew. It grew very, very rapidly, and I am grateful to
have participated in that.
Cherie Young: Through the years, when I started working in
intraoperative monitoring, in the beginning, we were only
doing somatosensory evoked potentials. Do you remember
that?
Dr. Leo Happel: Yes, I do.
Cherie Young: And we evolved together with your oversight.
Dr. Leo Happel: The spine surgeon said, it's nice to be
able to prevent problems to the sensory system, but what we
really want to do is we want to protect the voluntary motor
pathways. And so in the 1980s there were people who were
trying to develop a method to evaluate the motor pathways, and
they started off with trying to do transcranial stimulation of
the motor cortex to evoke movement that we could then
record an electrical event associated with and thus assess
the motor pathways. This was crude to start off with, and the
parameters of stimulation were a little bit scary. This motor
evoked potential process began at St Louis, in the hospitals at
St Louis, and they would stimulate transcranially using
electrical pulses of about 2000 volts. And I remember going to a
meeting once where somebody stood up and asked, "don't they
call that capital punishment"? Well, be that as it may, we got
better and better at it, and we got the techniques of
stimulation the motor cortex down a little bit better where
we could use much, much lower voltages, and that was much more
appealing. And now there is a fairly common use of motor
evoked potentials during spine surgery as well as somatosensory
evoked potentials. The more tracks that we can evaluate
during surgery, the more accurate we can be in stating
that things are working okay. The surgeons got to be pretty
demanding. And as surgical procedures were underway, they
would frequently ask, "How is everything"? And expecting an
instantaneous response, which we couldn't give. It took about
three minutes to perform the testing that would evaluate
these pathways, and we would have to say, "Well, you know,
give us a couple of minutes. We'll let you know in a couple
of minutes if everything is okay", which we had to then do
the testing, and then we could give them a response to say yes
or no, everything was okay or not okay.
Cherie Young: And to facilitate some of those requests, I recall
you being able to create instrumentation maybe, to help
us along the way.
Dr. Leo Happel: Yeah, we had several things that we could
use. I'm not really a surgical equipment manufacturer, but
there were pieces of surgical equipment that we could use that
would facilitate these recordings. But that was
something that really has not become very commonplace. Most
places still use transcortical stimulation and the recording
from muscle groups in the legs to see if there is conduction in
the motor pathways.
Cherie Young: And before that time, remember when we started
descending evoked potentials, before we had the motors, we
were doing descending evoke potential stimulation. And I
remember we had to apply the needles, but they had a Teflon
coating. So you would actually shave those needles for us to
remove some of the Teflon coating so we could stimulate.
Dr. Leo Happel: We could stimulate cervical spinal cord
and record motor events in the legs. That was a process that we
went through for a while, but then eventually the
transcortical stimulation took over from there, and it was a
little bit easier to place electrodes on the scalp.
Cherie Young: Right? No more shaving down electrodes.
Dr. Leo Happel: No more shaving down electrodes, no more
trying...
Cherie Young: And having them re-sterilized. And I remember,
in one of the cases they'd asked for the Happel adapter. Tell us
about that?
Dr. Leo Happel: Oh, uh.
Cherie Young: I remember all kinds of things.
Dr. Leo Happel: Yeah, you remember better than I do. I'm
trying to remember what that was. I remember we had an
adapter, but I don't really quite recall what that was.
Cherie Young: It was part of the stimulation process. Might have
to refer to Andy King on that one.
Dr. Leo Happel: Yeah, it can refresh my memory here. I hope
I'm not having the same problem that my wife has. My wife has
Alzheimer's, and so this really changed my course of action,
because my wife started to develop Alzheimer's about 2015
or so, and I was her primary caretaker. And I was her primary
caretaker until 2023 when I had an event myself. I had an
intestinal bleed, and in the middle of the night, one night,
I almost bled to death. And that changed the course of pretty
much everything for me. Following that bleed, I got to
be very weak, and in early 2024 I fell and broke my ankle. And
the orthopedist that I went to, x-rayed my leg, x-rayed my
ankle, and he told me, he says, "You know, I've seen this happen
time and time again. I can put plates and screws on the broken
bones, but I can tell you that if I do that, you're going to
have a lot worse arthritis than if I just leave it alone and let
it heal". And so I took his advice, and I let it alone, and
it has healed, but it still gives me problems. I still have
to walk with a cane, and so have not quite recovered from a
broken ankle.
Cherie Young: Goodness. Well, we're sorry to hear about Bonnie
and yeah, sometimes we have to make hard choices in life. It's
not easy.
Dr. Leo Happel: Yeah, it really isn't. It really is not.
Cherie Young: So I'd like to hear one more story from you. I
want to hear the story, since you've retired, the call that
you recently received. You said, people still call you.
Dr. Leo Happel: Yes, okay.
Cherie Young: Let's talk about that quick call. Well, it wasn't
a quick call. It was a quick call to you, but it was (laughs)
Dr. Leo Happel: Okay. Here's the story. There was a young man who
was born with a birth injury to his right brachial plexus. This
injury was so bad that he had a flail arm as a result. He had no
voluntary movement in his arm, and so it was not a good idea to
try to repair this injury right away. The surgeon chose to wait
and see what was going to happen, and he waited till the
child was six years old. When the child was six years old, the
neurosurgeon chose to do surgery on his right brachial plexus,
and he calls me on the telephone. He says, "I'm in the
operating room now", he says, "I've got his brachial plexus
exposed". He says "I'm stimulating elements in his
right brachial plexus, and I'm watching his right hand and the
fingers of his right hand move. How can that possibly be? This
child has no voluntary movement whatsoever. How can that be?
What does it mean?" And so I explained to him, over the
course of six years, this child has had a small number of axons
grow from his right brachial plexus all the way out to the
intrinsic muscles of his hand. These fibers are very few in
number, and they create very small motor units. What you are
doing when you stimulate is you are artificially synchronizing
what few motor units remain, going from his right brachial
plexus down to his hand, and those few motor units, when they
are synchronized together, can produce visible contraction of
his hand. However, those motor units are so small that they
cannot be incorporated into voluntary movements to create
voluntary movements of his right hand. So you have to treat this
as if this was a complete injury to his right brachial plexus,
and those elements in his right brachial plexus still have to be
repaired. That was a complicated picture, and it was a call that
I had to make that indeed, his injury was still complete. It
was not a case of his injuries had healed. It's just that the
case of those nerve fibers grew back, just a few of them over
the length of his arm, and they could now mediate movement if
they were synchronized by electrical stimulation.
Cherie Young: Very impressive. You never cease to amaze me Dr
Happel.
Dr. Leo Happel: Oh, well, this what I was meant to do. This was
my calling.
Cherie Young: I truly believe that.
Dr. Leo Happel: I had the electronics background, I had
the biology background, and the circumstances just came up where
I could pull all of that together, and it created a
wonderful career for me.
Cherie Young: Right? Well, I would like to say thank you very
much for taking the time to do the interview. From ASET
Historical Society, we truly appreciate the opportunity to
interview you today and hear all of your history and how evoked
potential and intraoperative monitoring have evolved today.
Dr. Leo Happel: Well, it means a lot to me that you were the
person on the other side of the screen here asking the
questions, because I have to tell you that I appreciate all
that you have done. You know you were a gifted person, and I
recognize that you were a gifted technologist, and I have had
ample opportunity to recommend you as someone who was
particularly capable. So it's been a pleasure working with
you.
Cherie Young: Thank you very much. That is very sweet. I
wouldn't be where I am without your help, and
Dr. Leo Happel: probably works both ways
Cherie Young: You were my mentor and I was excited when I was
asked to do this interview for you. So...
Dr. Leo Happel: Cool. Well, I'm glad to do it. Glad to do it for
the society. Glad to do it for you in particular.
Cherie Young: Dr Happel, you've done a significant amount of
research in our field, and I'm sure you have been awarded.
Dr. Leo Happel: I have been and it was indeed a great and
special honor that was conveyed on me at the ASNM meeting in
Orlando, Florida, I was designated as the recipient of
the Richard Brown Lifetime Achievement Award in operative
monitoring, and I still have that plaque, which has a special
place in my heart. Richard Brown is no longer with us, but he was
a very good friend during his lifetime, and he really meant a
lot to me.
Cherie Young: Well, we appreciate you being one of the
pioneers in our field and sharing your wealth of knowledge
with all of us.
Dr. Leo Happel: Thank you very much.
Ask follow-up questions or revisit key timestamps.
Dr. Leo Happel, a PhD neurophysiologist and a pioneer in intraoperative neuromonitoring (IONM), reflects on his career beginning in the early 1970s at LSU and Charity Hospital. He describes the transition from assembling DIY monitoring equipment to the development of standardized tools and professional certification boards like ASNM. The interview covers his work in peripheral nerve surgery with Dr. David Klein, the inception of spinal monitoring with Dr. Andrew King, and his contributions to patient safety through practices like 'Happel's Law' and blood pressure management during surgery. Dr. Happel emphasizes that despite the high costs and insurance hurdles, the improved patient outcomes justify the necessity of neuromonitoring in modern medicine.
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